Overview
- Threshold analysis run on four HIV vaccine trials: HVTN705, HVTN702,
HVTN505, and RV144, as well as HVTN 705 + RV144 combined.
- Analyses run on vaccine participants only. (Marker variable values
were missing or 0 for most placebo participants in each study.)
- Thresholds were selected over a grid of increments of 0.1, from the
lowest marker value to the highest value of the marker such that there
are at least 3 endpoints with a marker at least that value
- Reference timepoint was chosen as the timepoint of the latest
endpoint
- For VE graphs, placebo risk was determined by using all data from
the placebo arm, regardless of whether the marker was sampled. Note: For
HVTN705, there are 210 placebo participants missing their
event/censoring time variable. These are excluded when calculating the
placebo risk.
- Vaccine efficacy confidence intervals cutoffs between -1 and 1.
HVTN 705
- Adjustment covariates: Age, RSA, BMI,
Riskscore
- Event time variable: Ttilde.D210
- Event type variable: Delta.D210
- Weight variable: wt.D210
- Reference timepoint: 552 days
- Filter: !is.na(Ttilde.D210)
- All learners: GLM
IgG V1V2 B.CaseA-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.0515 |
0.00678 |
0.03820 |
0.0648 |
| 0.1 |
0.9030 |
1.26 |
0.0496 |
0.00777 |
0.03440 |
0.0648 |
| 0.2 |
0.9030 |
1.58 |
0.0496 |
0.00777 |
0.03440 |
0.0648 |
| 0.3 |
0.9030 |
2.00 |
0.0496 |
0.00777 |
0.03440 |
0.0648 |
| 0.4 |
0.9030 |
2.51 |
0.0496 |
0.00777 |
0.03440 |
0.0648 |
| 0.5 |
0.9030 |
3.16 |
0.0496 |
0.00777 |
0.03440 |
0.0648 |
| 0.6 |
0.9030 |
3.98 |
0.0496 |
0.00777 |
0.03440 |
0.0648 |
| 0.7 |
0.9030 |
5.01 |
0.0496 |
0.00777 |
0.03440 |
0.0648 |
| 0.8 |
0.9030 |
6.31 |
0.0496 |
0.00777 |
0.03440 |
0.0648 |
| 0.9 |
0.9030 |
7.94 |
0.0496 |
0.00777 |
0.03440 |
0.0648 |
| 1.0 |
0.9030 |
10.00 |
0.0496 |
0.00777 |
0.03440 |
0.0648 |
| 1.1 |
0.8980 |
12.60 |
0.0496 |
0.00782 |
0.03430 |
0.0649 |
| 1.2 |
0.8810 |
15.80 |
0.0496 |
0.00794 |
0.03400 |
0.0652 |
| 1.3 |
0.8810 |
20.00 |
0.0496 |
0.00794 |
0.03400 |
0.0652 |
| 1.4 |
0.8810 |
25.10 |
0.0496 |
0.00794 |
0.03400 |
0.0652 |
| 1.5 |
0.8700 |
31.60 |
0.0496 |
0.00803 |
0.03390 |
0.0653 |
| 1.6 |
0.8550 |
39.80 |
0.0496 |
0.00814 |
0.03360 |
0.0656 |
| 1.7 |
0.8280 |
50.10 |
0.0496 |
0.00815 |
0.03360 |
0.0656 |
| 1.8 |
0.8080 |
63.10 |
0.0496 |
0.00818 |
0.03360 |
0.0656 |
| 1.9 |
0.8040 |
79.40 |
0.0496 |
0.00813 |
0.03370 |
0.0655 |
| 2.0 |
0.7830 |
100.00 |
0.0496 |
0.00825 |
0.03340 |
0.0658 |
| 2.1 |
0.7690 |
126.00 |
0.0496 |
0.00825 |
0.03340 |
0.0658 |
| 2.2 |
0.7570 |
158.00 |
0.0496 |
0.00837 |
0.03320 |
0.0660 |
| 2.3 |
0.7350 |
200.00 |
0.0496 |
0.00853 |
0.03290 |
0.0663 |
| 2.4 |
0.7010 |
251.00 |
0.0496 |
0.00875 |
0.03240 |
0.0668 |
| 2.5 |
0.6830 |
316.00 |
0.0496 |
0.00879 |
0.03240 |
0.0668 |
| 2.6 |
0.6420 |
398.00 |
0.0496 |
0.00929 |
0.03140 |
0.0678 |
| 2.7 |
0.5890 |
501.00 |
0.0496 |
0.01020 |
0.02970 |
0.0695 |
| 2.8 |
0.5410 |
631.00 |
0.0496 |
0.01080 |
0.02840 |
0.0708 |
| 2.9 |
0.5110 |
794.00 |
0.0496 |
0.01090 |
0.02830 |
0.0709 |
| 3.0 |
0.4690 |
1000.00 |
0.0496 |
0.01110 |
0.02790 |
0.0713 |
| 3.1 |
0.4250 |
1260.00 |
0.0433 |
0.01090 |
0.02200 |
0.0646 |
| 3.2 |
0.4020 |
1580.00 |
0.0424 |
0.01050 |
0.02180 |
0.0631 |
| 3.3 |
0.3520 |
2000.00 |
0.0424 |
0.01170 |
0.01940 |
0.0655 |
| 3.4 |
0.3250 |
2510.00 |
0.0424 |
0.01130 |
0.02020 |
0.0647 |
| 3.5 |
0.2940 |
3160.00 |
0.0424 |
0.01280 |
0.01730 |
0.0676 |
| 3.6 |
0.2680 |
3980.00 |
0.0424 |
0.01440 |
0.01420 |
0.0707 |
| 3.7 |
0.2340 |
5010.00 |
0.0424 |
0.01500 |
0.01300 |
0.0719 |
| 3.8 |
0.2060 |
6310.00 |
0.0424 |
0.01580 |
0.01140 |
0.0735 |
| 3.9 |
0.1750 |
7940.00 |
0.0424 |
0.01510 |
0.01290 |
0.0720 |
| 4.0 |
0.1360 |
10000.00 |
0.0424 |
0.02220 |
-0.00115 |
0.0860 |
| 4.1 |
0.1190 |
12600.00 |
0.0424 |
0.02860 |
-0.01360 |
0.0985 |
| 4.2 |
0.0917 |
15800.00 |
0.0424 |
0.03270 |
-0.02160 |
0.1060 |
| 4.3 |
0.0722 |
20000.00 |
0.0348 |
0.02780 |
-0.01970 |
0.0892 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.0515 |
0.00678 |
0.03570 |
0.0650 |
| 0.1 |
1.26 |
0.9030 |
0.0490 |
0.00777 |
0.03380 |
0.0643 |
| 0.2 |
1.58 |
0.9030 |
0.0490 |
0.00777 |
0.03380 |
0.0643 |
| 0.3 |
2.00 |
0.9030 |
0.0490 |
0.00777 |
0.03380 |
0.0643 |
| 0.4 |
2.51 |
0.9030 |
0.0490 |
0.00777 |
0.03380 |
0.0643 |
| 0.5 |
3.16 |
0.9030 |
0.0490 |
0.00777 |
0.03380 |
0.0643 |
| 0.6 |
3.98 |
0.9030 |
0.0490 |
0.00777 |
0.03380 |
0.0643 |
| 0.7 |
5.01 |
0.9030 |
0.0490 |
0.00777 |
0.03380 |
0.0643 |
| 0.8 |
6.31 |
0.9030 |
0.0490 |
0.00777 |
0.03380 |
0.0643 |
| 0.9 |
7.94 |
0.9030 |
0.0490 |
0.00777 |
0.03380 |
0.0643 |
| 1.0 |
10.00 |
0.9030 |
0.0490 |
0.00777 |
0.03380 |
0.0643 |
| 1.1 |
12.60 |
0.8980 |
0.0493 |
0.00782 |
0.03400 |
0.0646 |
| 1.2 |
15.80 |
0.8810 |
0.0501 |
0.00794 |
0.03450 |
0.0656 |
| 1.3 |
20.00 |
0.8810 |
0.0501 |
0.00794 |
0.03450 |
0.0656 |
| 1.4 |
25.10 |
0.8810 |
0.0501 |
0.00794 |
0.03450 |
0.0656 |
| 1.5 |
31.60 |
0.8700 |
0.0506 |
0.00803 |
0.03480 |
0.0663 |
| 1.6 |
39.80 |
0.8550 |
0.0508 |
0.00814 |
0.03490 |
0.0668 |
| 1.7 |
50.10 |
0.8280 |
0.0499 |
0.00815 |
0.03390 |
0.0659 |
| 1.8 |
63.10 |
0.8080 |
0.0490 |
0.00818 |
0.03300 |
0.0651 |
| 1.9 |
79.40 |
0.8040 |
0.0482 |
0.00813 |
0.03220 |
0.0641 |
| 2.0 |
100.00 |
0.7830 |
0.0484 |
0.00825 |
0.03220 |
0.0646 |
| 2.1 |
126.00 |
0.7690 |
0.0477 |
0.00825 |
0.03150 |
0.0639 |
| 2.2 |
158.00 |
0.7570 |
0.0484 |
0.00837 |
0.03200 |
0.0648 |
| 2.3 |
200.00 |
0.7350 |
0.0486 |
0.00853 |
0.03180 |
0.0653 |
| 2.4 |
251.00 |
0.7010 |
0.0483 |
0.00875 |
0.03110 |
0.0654 |
| 2.5 |
316.00 |
0.6830 |
0.0478 |
0.00879 |
0.03060 |
0.0650 |
| 2.6 |
398.00 |
0.6420 |
0.0495 |
0.00929 |
0.03130 |
0.0677 |
| 2.7 |
501.00 |
0.5890 |
0.0535 |
0.01020 |
0.03360 |
0.0734 |
| 2.8 |
631.00 |
0.5410 |
0.0562 |
0.01080 |
0.03500 |
0.0775 |
| 2.9 |
794.00 |
0.5110 |
0.0533 |
0.01090 |
0.03200 |
0.0746 |
| 3.0 |
1000.00 |
0.4690 |
0.0501 |
0.01110 |
0.02840 |
0.0718 |
| 3.1 |
1260.00 |
0.4250 |
0.0433 |
0.01090 |
0.02200 |
0.0646 |
| 3.2 |
1580.00 |
0.4020 |
0.0410 |
0.01050 |
0.02040 |
0.0616 |
| 3.3 |
2000.00 |
0.3520 |
0.0425 |
0.01170 |
0.01950 |
0.0655 |
| 3.4 |
2510.00 |
0.3250 |
0.0381 |
0.01130 |
0.01580 |
0.0603 |
| 3.5 |
3160.00 |
0.2940 |
0.0429 |
0.01280 |
0.01780 |
0.0680 |
| 3.6 |
3980.00 |
0.2680 |
0.0461 |
0.01440 |
0.01780 |
0.0744 |
| 3.7 |
5010.00 |
0.2340 |
0.0450 |
0.01500 |
0.01550 |
0.0744 |
| 3.8 |
6310.00 |
0.2060 |
0.0427 |
0.01580 |
0.01170 |
0.0738 |
| 3.9 |
7940.00 |
0.1750 |
0.0325 |
0.01510 |
0.00291 |
0.0620 |
| 4.0 |
10000.00 |
0.1360 |
0.0451 |
0.02220 |
0.00149 |
0.0887 |
| 4.1 |
12600.00 |
0.1190 |
0.0511 |
0.02860 |
-0.00500 |
0.1070 |
| 4.2 |
15800.00 |
0.0917 |
0.0514 |
0.03270 |
-0.01260 |
0.1150 |
| 4.3 |
20000.00 |
0.0722 |
0.0348 |
0.02780 |
-0.01970 |
0.0892 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.122 |
0.157 |
-0.186 |
0.430 |
| 0.1 |
0.9030 |
1.26 |
0.155 |
0.168 |
-0.174 |
0.483 |
| 0.2 |
0.9030 |
1.58 |
0.155 |
0.168 |
-0.174 |
0.483 |
| 0.3 |
0.9030 |
2.00 |
0.155 |
0.168 |
-0.174 |
0.483 |
| 0.4 |
0.9030 |
2.51 |
0.155 |
0.168 |
-0.174 |
0.483 |
| 0.5 |
0.9030 |
3.16 |
0.155 |
0.168 |
-0.174 |
0.483 |
| 0.6 |
0.9030 |
3.98 |
0.155 |
0.168 |
-0.174 |
0.483 |
| 0.7 |
0.9030 |
5.01 |
0.155 |
0.168 |
-0.174 |
0.483 |
| 0.8 |
0.9030 |
6.31 |
0.155 |
0.168 |
-0.174 |
0.483 |
| 0.9 |
0.9030 |
7.94 |
0.155 |
0.168 |
-0.174 |
0.483 |
| 1.0 |
0.9030 |
10.00 |
0.155 |
0.168 |
-0.174 |
0.483 |
| 1.1 |
0.8980 |
12.60 |
0.155 |
0.168 |
-0.175 |
0.484 |
| 1.2 |
0.8810 |
15.80 |
0.155 |
0.170 |
-0.178 |
0.488 |
| 1.3 |
0.8810 |
20.00 |
0.155 |
0.170 |
-0.178 |
0.488 |
| 1.4 |
0.8810 |
25.10 |
0.155 |
0.170 |
-0.178 |
0.488 |
| 1.5 |
0.8700 |
31.60 |
0.155 |
0.171 |
-0.181 |
0.490 |
| 1.6 |
0.8550 |
39.80 |
0.155 |
0.173 |
-0.183 |
0.493 |
| 1.7 |
0.8280 |
50.10 |
0.155 |
0.173 |
-0.184 |
0.493 |
| 1.8 |
0.8080 |
63.10 |
0.155 |
0.173 |
-0.185 |
0.494 |
| 1.9 |
0.8040 |
79.40 |
0.155 |
0.172 |
-0.183 |
0.493 |
| 2.0 |
0.7830 |
100.00 |
0.155 |
0.174 |
-0.186 |
0.496 |
| 2.1 |
0.7690 |
126.00 |
0.155 |
0.174 |
-0.186 |
0.496 |
| 2.2 |
0.7570 |
158.00 |
0.155 |
0.176 |
-0.190 |
0.499 |
| 2.3 |
0.7350 |
200.00 |
0.155 |
0.178 |
-0.194 |
0.504 |
| 2.4 |
0.7010 |
251.00 |
0.155 |
0.181 |
-0.200 |
0.510 |
| 2.5 |
0.6830 |
316.00 |
0.155 |
0.182 |
-0.201 |
0.511 |
| 2.6 |
0.6420 |
398.00 |
0.155 |
0.189 |
-0.215 |
0.525 |
| 2.7 |
0.5890 |
501.00 |
0.155 |
0.201 |
-0.240 |
0.549 |
| 2.8 |
0.5410 |
631.00 |
0.155 |
0.211 |
-0.259 |
0.569 |
| 2.9 |
0.5110 |
794.00 |
0.155 |
0.212 |
-0.260 |
0.570 |
| 3.0 |
0.4690 |
1000.00 |
0.155 |
0.215 |
-0.266 |
0.575 |
| 3.1 |
0.4250 |
1260.00 |
0.262 |
0.206 |
-0.141 |
0.665 |
| 3.2 |
0.4020 |
1580.00 |
0.277 |
0.200 |
-0.115 |
0.668 |
| 3.3 |
0.3520 |
2000.00 |
0.277 |
0.219 |
-0.152 |
0.705 |
| 3.4 |
0.3250 |
2510.00 |
0.277 |
0.212 |
-0.140 |
0.693 |
| 3.5 |
0.2940 |
3160.00 |
0.277 |
0.236 |
-0.185 |
0.738 |
| 3.6 |
0.2680 |
3980.00 |
0.277 |
0.261 |
-0.235 |
0.788 |
| 3.7 |
0.2340 |
5010.00 |
0.277 |
0.271 |
-0.253 |
0.807 |
| 3.8 |
0.2060 |
6310.00 |
0.277 |
0.284 |
-0.280 |
0.833 |
| 3.9 |
0.1750 |
7940.00 |
0.277 |
0.272 |
-0.256 |
0.809 |
| 4.0 |
0.1360 |
10000.00 |
0.277 |
0.389 |
-0.486 |
1.040 |
| 4.1 |
0.1190 |
12600.00 |
0.277 |
0.495 |
-0.694 |
1.250 |
| 4.2 |
0.0917 |
15800.00 |
0.277 |
0.563 |
-0.827 |
1.380 |
| 4.3 |
0.0722 |
20000.00 |
0.408 |
0.479 |
-0.531 |
1.350 |
IgG V1V2 C.1086-gp70
Monotone

| 0.0 |
1.000 |
1.00 |
0.0515 |
0.00678 |
0.03820 |
0.0648 |
| 0.1 |
0.974 |
1.26 |
0.0514 |
0.00761 |
0.03650 |
0.0663 |
| 0.2 |
0.974 |
1.58 |
0.0514 |
0.00761 |
0.03650 |
0.0663 |
| 0.3 |
0.974 |
2.00 |
0.0514 |
0.00761 |
0.03650 |
0.0663 |
| 0.4 |
0.974 |
2.51 |
0.0514 |
0.00761 |
0.03650 |
0.0663 |
| 0.5 |
0.974 |
3.16 |
0.0514 |
0.00761 |
0.03650 |
0.0663 |
| 0.6 |
0.974 |
3.98 |
0.0514 |
0.00761 |
0.03650 |
0.0663 |
| 0.7 |
0.974 |
5.01 |
0.0514 |
0.00761 |
0.03650 |
0.0663 |
| 0.8 |
0.974 |
6.31 |
0.0514 |
0.00761 |
0.03650 |
0.0663 |
| 0.9 |
0.974 |
7.94 |
0.0514 |
0.00761 |
0.03650 |
0.0663 |
| 1.0 |
0.974 |
10.00 |
0.0514 |
0.00761 |
0.03650 |
0.0663 |
| 1.1 |
0.973 |
12.60 |
0.0514 |
0.00752 |
0.03670 |
0.0661 |
| 1.2 |
0.973 |
15.80 |
0.0514 |
0.00752 |
0.03670 |
0.0661 |
| 1.3 |
0.973 |
20.00 |
0.0514 |
0.00752 |
0.03670 |
0.0661 |
| 1.4 |
0.970 |
25.10 |
0.0514 |
0.00754 |
0.03660 |
0.0662 |
| 1.5 |
0.970 |
31.60 |
0.0514 |
0.00754 |
0.03660 |
0.0662 |
| 1.6 |
0.970 |
39.80 |
0.0514 |
0.00754 |
0.03660 |
0.0662 |
| 1.7 |
0.964 |
50.10 |
0.0514 |
0.00749 |
0.03670 |
0.0661 |
| 1.8 |
0.961 |
63.10 |
0.0514 |
0.00753 |
0.03660 |
0.0662 |
| 1.9 |
0.961 |
79.40 |
0.0514 |
0.00753 |
0.03660 |
0.0662 |
| 2.0 |
0.958 |
100.00 |
0.0514 |
0.00756 |
0.03660 |
0.0662 |
| 2.1 |
0.952 |
126.00 |
0.0514 |
0.00761 |
0.03650 |
0.0663 |
| 2.2 |
0.949 |
158.00 |
0.0514 |
0.00764 |
0.03640 |
0.0664 |
| 2.3 |
0.944 |
200.00 |
0.0514 |
0.00769 |
0.03630 |
0.0665 |
| 2.4 |
0.941 |
251.00 |
0.0514 |
0.00772 |
0.03630 |
0.0665 |
| 2.5 |
0.920 |
316.00 |
0.0514 |
0.00778 |
0.03620 |
0.0666 |
| 2.6 |
0.909 |
398.00 |
0.0514 |
0.00792 |
0.03590 |
0.0669 |
| 2.7 |
0.894 |
501.00 |
0.0514 |
0.00799 |
0.03570 |
0.0671 |
| 2.8 |
0.859 |
631.00 |
0.0514 |
0.00843 |
0.03490 |
0.0679 |
| 2.9 |
0.818 |
794.00 |
0.0514 |
0.00861 |
0.03450 |
0.0683 |
| 3.0 |
0.787 |
1000.00 |
0.0514 |
0.00872 |
0.03430 |
0.0685 |
| 3.1 |
0.756 |
1260.00 |
0.0514 |
0.00898 |
0.03380 |
0.0690 |
| 3.2 |
0.725 |
1580.00 |
0.0514 |
0.00907 |
0.03360 |
0.0692 |
| 3.3 |
0.675 |
2000.00 |
0.0514 |
0.00947 |
0.03280 |
0.0700 |
| 3.4 |
0.621 |
2510.00 |
0.0514 |
0.00993 |
0.03190 |
0.0709 |
| 3.5 |
0.566 |
3160.00 |
0.0514 |
0.01040 |
0.03100 |
0.0718 |
| 3.6 |
0.490 |
3980.00 |
0.0514 |
0.01160 |
0.02870 |
0.0741 |
| 3.7 |
0.436 |
5010.00 |
0.0514 |
0.01160 |
0.02870 |
0.0741 |
| 3.8 |
0.390 |
6310.00 |
0.0514 |
0.01180 |
0.02820 |
0.0746 |
| 3.9 |
0.330 |
7940.00 |
0.0514 |
0.01320 |
0.02550 |
0.0773 |
| 4.0 |
0.286 |
10000.00 |
0.0514 |
0.01610 |
0.01980 |
0.0830 |
| 4.1 |
0.235 |
12600.00 |
0.0514 |
0.01650 |
0.01900 |
0.0838 |
| 4.2 |
0.191 |
15800.00 |
0.0467 |
0.01760 |
0.01220 |
0.0812 |
| 4.3 |
0.150 |
20000.00 |
0.0467 |
0.02020 |
0.00711 |
0.0863 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.0515 |
0.00678 |
0.03570 |
0.0650 |
| 0.1 |
1.26 |
0.974 |
0.0509 |
0.00761 |
0.03600 |
0.0658 |
| 0.2 |
1.58 |
0.974 |
0.0509 |
0.00761 |
0.03600 |
0.0658 |
| 0.3 |
2.00 |
0.974 |
0.0509 |
0.00761 |
0.03600 |
0.0658 |
| 0.4 |
2.51 |
0.974 |
0.0509 |
0.00761 |
0.03600 |
0.0658 |
| 0.5 |
3.16 |
0.974 |
0.0509 |
0.00761 |
0.03600 |
0.0658 |
| 0.6 |
3.98 |
0.974 |
0.0509 |
0.00761 |
0.03600 |
0.0658 |
| 0.7 |
5.01 |
0.974 |
0.0509 |
0.00761 |
0.03600 |
0.0658 |
| 0.8 |
6.31 |
0.974 |
0.0509 |
0.00761 |
0.03600 |
0.0658 |
| 0.9 |
7.94 |
0.974 |
0.0509 |
0.00761 |
0.03600 |
0.0658 |
| 1.0 |
10.00 |
0.974 |
0.0509 |
0.00761 |
0.03600 |
0.0658 |
| 1.1 |
12.60 |
0.973 |
0.0498 |
0.00752 |
0.03510 |
0.0646 |
| 1.2 |
15.80 |
0.973 |
0.0498 |
0.00752 |
0.03510 |
0.0646 |
| 1.3 |
20.00 |
0.973 |
0.0498 |
0.00752 |
0.03510 |
0.0646 |
| 1.4 |
25.10 |
0.970 |
0.0500 |
0.00754 |
0.03520 |
0.0648 |
| 1.5 |
31.60 |
0.970 |
0.0500 |
0.00754 |
0.03520 |
0.0648 |
| 1.6 |
39.80 |
0.970 |
0.0500 |
0.00754 |
0.03520 |
0.0648 |
| 1.7 |
50.10 |
0.964 |
0.0493 |
0.00749 |
0.03460 |
0.0639 |
| 1.8 |
63.10 |
0.961 |
0.0495 |
0.00753 |
0.03480 |
0.0643 |
| 1.9 |
79.40 |
0.961 |
0.0495 |
0.00753 |
0.03480 |
0.0643 |
| 2.0 |
100.00 |
0.958 |
0.0497 |
0.00756 |
0.03490 |
0.0645 |
| 2.1 |
126.00 |
0.952 |
0.0501 |
0.00761 |
0.03520 |
0.0650 |
| 2.2 |
158.00 |
0.949 |
0.0503 |
0.00764 |
0.03530 |
0.0653 |
| 2.3 |
200.00 |
0.944 |
0.0506 |
0.00769 |
0.03550 |
0.0657 |
| 2.4 |
251.00 |
0.941 |
0.0508 |
0.00772 |
0.03560 |
0.0659 |
| 2.5 |
316.00 |
0.920 |
0.0506 |
0.00778 |
0.03530 |
0.0658 |
| 2.6 |
398.00 |
0.909 |
0.0515 |
0.00792 |
0.03600 |
0.0670 |
| 2.7 |
501.00 |
0.894 |
0.0514 |
0.00799 |
0.03570 |
0.0670 |
| 2.8 |
631.00 |
0.859 |
0.0542 |
0.00843 |
0.03770 |
0.0707 |
| 2.9 |
794.00 |
0.818 |
0.0541 |
0.00861 |
0.03720 |
0.0710 |
| 3.0 |
1000.00 |
0.787 |
0.0529 |
0.00872 |
0.03580 |
0.0700 |
| 3.1 |
1260.00 |
0.756 |
0.0539 |
0.00898 |
0.03630 |
0.0715 |
| 3.2 |
1580.00 |
0.725 |
0.0524 |
0.00907 |
0.03460 |
0.0702 |
| 3.3 |
2000.00 |
0.675 |
0.0532 |
0.00947 |
0.03460 |
0.0717 |
| 3.4 |
2510.00 |
0.621 |
0.0529 |
0.00993 |
0.03340 |
0.0723 |
| 3.5 |
3160.00 |
0.566 |
0.0542 |
0.01040 |
0.03380 |
0.0746 |
| 3.6 |
3980.00 |
0.490 |
0.0581 |
0.01160 |
0.03540 |
0.0808 |
| 3.7 |
5010.00 |
0.436 |
0.0537 |
0.01160 |
0.03100 |
0.0764 |
| 3.8 |
6310.00 |
0.390 |
0.0501 |
0.01180 |
0.02690 |
0.0732 |
| 3.9 |
7940.00 |
0.330 |
0.0518 |
0.01320 |
0.02590 |
0.0777 |
| 4.0 |
10000.00 |
0.286 |
0.0612 |
0.01610 |
0.02970 |
0.0928 |
| 4.1 |
12600.00 |
0.235 |
0.0515 |
0.01650 |
0.01910 |
0.0839 |
| 4.2 |
15800.00 |
0.191 |
0.0443 |
0.01760 |
0.00982 |
0.0788 |
| 4.3 |
20000.00 |
0.150 |
0.0491 |
0.02020 |
0.00953 |
0.0888 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.122 |
0.157 |
-0.186 |
0.430 |
| 0.1 |
0.974 |
1.26 |
0.124 |
0.168 |
-0.205 |
0.453 |
| 0.2 |
0.974 |
1.58 |
0.124 |
0.168 |
-0.205 |
0.453 |
| 0.3 |
0.974 |
2.00 |
0.124 |
0.168 |
-0.205 |
0.453 |
| 0.4 |
0.974 |
2.51 |
0.124 |
0.168 |
-0.205 |
0.453 |
| 0.5 |
0.974 |
3.16 |
0.124 |
0.168 |
-0.205 |
0.453 |
| 0.6 |
0.974 |
3.98 |
0.124 |
0.168 |
-0.205 |
0.453 |
| 0.7 |
0.974 |
5.01 |
0.124 |
0.168 |
-0.205 |
0.453 |
| 0.8 |
0.974 |
6.31 |
0.124 |
0.168 |
-0.205 |
0.453 |
| 0.9 |
0.974 |
7.94 |
0.124 |
0.168 |
-0.205 |
0.453 |
| 1.0 |
0.974 |
10.00 |
0.124 |
0.168 |
-0.205 |
0.453 |
| 1.1 |
0.973 |
12.60 |
0.124 |
0.166 |
-0.202 |
0.450 |
| 1.2 |
0.973 |
15.80 |
0.124 |
0.166 |
-0.202 |
0.450 |
| 1.3 |
0.973 |
20.00 |
0.124 |
0.166 |
-0.202 |
0.450 |
| 1.4 |
0.970 |
25.10 |
0.124 |
0.167 |
-0.203 |
0.451 |
| 1.5 |
0.970 |
31.60 |
0.124 |
0.167 |
-0.203 |
0.451 |
| 1.6 |
0.970 |
39.80 |
0.124 |
0.167 |
-0.203 |
0.451 |
| 1.7 |
0.964 |
50.10 |
0.124 |
0.166 |
-0.201 |
0.450 |
| 1.8 |
0.961 |
63.10 |
0.124 |
0.167 |
-0.203 |
0.451 |
| 1.9 |
0.961 |
79.40 |
0.124 |
0.167 |
-0.203 |
0.451 |
| 2.0 |
0.958 |
100.00 |
0.124 |
0.167 |
-0.203 |
0.452 |
| 2.1 |
0.952 |
126.00 |
0.124 |
0.168 |
-0.205 |
0.453 |
| 2.2 |
0.949 |
158.00 |
0.124 |
0.168 |
-0.205 |
0.454 |
| 2.3 |
0.944 |
200.00 |
0.124 |
0.169 |
-0.207 |
0.455 |
| 2.4 |
0.941 |
251.00 |
0.124 |
0.169 |
-0.207 |
0.456 |
| 2.5 |
0.920 |
316.00 |
0.124 |
0.170 |
-0.209 |
0.457 |
| 2.6 |
0.909 |
398.00 |
0.124 |
0.172 |
-0.213 |
0.461 |
| 2.7 |
0.894 |
501.00 |
0.124 |
0.173 |
-0.214 |
0.463 |
| 2.8 |
0.859 |
631.00 |
0.124 |
0.179 |
-0.226 |
0.474 |
| 2.9 |
0.818 |
794.00 |
0.124 |
0.181 |
-0.231 |
0.479 |
| 3.0 |
0.787 |
1000.00 |
0.124 |
0.183 |
-0.234 |
0.482 |
| 3.1 |
0.756 |
1260.00 |
0.124 |
0.186 |
-0.241 |
0.489 |
| 3.2 |
0.725 |
1580.00 |
0.124 |
0.188 |
-0.244 |
0.492 |
| 3.3 |
0.675 |
2000.00 |
0.124 |
0.193 |
-0.255 |
0.503 |
| 3.4 |
0.621 |
2510.00 |
0.124 |
0.200 |
-0.268 |
0.516 |
| 3.5 |
0.566 |
3160.00 |
0.124 |
0.207 |
-0.281 |
0.529 |
| 3.6 |
0.490 |
3980.00 |
0.124 |
0.224 |
-0.316 |
0.564 |
| 3.7 |
0.436 |
5010.00 |
0.124 |
0.224 |
-0.315 |
0.563 |
| 3.8 |
0.390 |
6310.00 |
0.124 |
0.228 |
-0.322 |
0.571 |
| 3.9 |
0.330 |
7940.00 |
0.124 |
0.249 |
-0.364 |
0.612 |
| 4.0 |
0.286 |
10000.00 |
0.124 |
0.294 |
-0.453 |
0.701 |
| 4.1 |
0.235 |
12600.00 |
0.124 |
0.301 |
-0.466 |
0.715 |
| 4.2 |
0.191 |
15800.00 |
0.204 |
0.315 |
-0.414 |
0.821 |
| 4.3 |
0.150 |
20000.00 |
0.204 |
0.358 |
-0.497 |
0.905 |
IgG3 V1V2 B.CaseA-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.0515 |
0.00678 |
0.03820 |
0.0648 |
| 0.1 |
0.5320 |
1.26 |
0.0496 |
0.01020 |
0.02960 |
0.0697 |
| 0.2 |
0.5230 |
1.58 |
0.0493 |
0.01020 |
0.02940 |
0.0692 |
| 0.3 |
0.5060 |
2.00 |
0.0493 |
0.01050 |
0.02870 |
0.0700 |
| 0.4 |
0.4910 |
2.51 |
0.0487 |
0.01040 |
0.02830 |
0.0691 |
| 0.5 |
0.4840 |
3.16 |
0.0469 |
0.01000 |
0.02730 |
0.0665 |
| 0.6 |
0.4610 |
3.98 |
0.0469 |
0.01040 |
0.02650 |
0.0673 |
| 0.7 |
0.4510 |
5.01 |
0.0455 |
0.01030 |
0.02530 |
0.0656 |
| 0.8 |
0.4420 |
6.31 |
0.0451 |
0.01030 |
0.02490 |
0.0652 |
| 0.9 |
0.4330 |
7.94 |
0.0451 |
0.01060 |
0.02440 |
0.0658 |
| 1.0 |
0.4270 |
10.00 |
0.0451 |
0.01040 |
0.02480 |
0.0654 |
| 1.1 |
0.3980 |
12.60 |
0.0451 |
0.01120 |
0.02310 |
0.0671 |
| 1.2 |
0.3890 |
15.80 |
0.0451 |
0.01100 |
0.02350 |
0.0666 |
| 1.3 |
0.3670 |
20.00 |
0.0451 |
0.01140 |
0.02280 |
0.0674 |
| 1.4 |
0.3420 |
25.10 |
0.0451 |
0.01260 |
0.02040 |
0.0697 |
| 1.5 |
0.3350 |
31.60 |
0.0436 |
0.01200 |
0.02010 |
0.0671 |
| 1.6 |
0.3190 |
39.80 |
0.0436 |
0.01220 |
0.01980 |
0.0675 |
| 1.7 |
0.3050 |
50.10 |
0.0436 |
0.01330 |
0.01750 |
0.0698 |
| 1.8 |
0.2740 |
63.10 |
0.0436 |
0.01400 |
0.01620 |
0.0710 |
| 1.9 |
0.2430 |
79.40 |
0.0436 |
0.01580 |
0.01270 |
0.0746 |
| 2.0 |
0.2340 |
100.00 |
0.0436 |
0.01610 |
0.01200 |
0.0752 |
| 2.1 |
0.2190 |
126.00 |
0.0436 |
0.01770 |
0.00890 |
0.0783 |
| 2.2 |
0.1910 |
158.00 |
0.0436 |
0.01550 |
0.01330 |
0.0739 |
| 2.3 |
0.1680 |
200.00 |
0.0436 |
0.01760 |
0.00908 |
0.0782 |
| 2.4 |
0.1510 |
251.00 |
0.0436 |
0.01870 |
0.00696 |
0.0803 |
| 2.5 |
0.1140 |
316.00 |
0.0436 |
0.02450 |
-0.00447 |
0.0917 |
| 2.6 |
0.1060 |
398.00 |
0.0436 |
0.02840 |
-0.01200 |
0.0992 |
| 2.7 |
0.0932 |
501.00 |
0.0436 |
0.06170 |
-0.07730 |
0.1650 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.0515 |
0.00678 |
3.57e-02 |
0.0650 |
| 0.1 |
1.26 |
0.5320 |
0.0496 |
0.01020 |
2.96e-02 |
0.0697 |
| 0.2 |
1.58 |
0.5230 |
0.0485 |
0.01020 |
2.86e-02 |
0.0684 |
| 0.3 |
2.00 |
0.5060 |
0.0501 |
0.01050 |
2.95e-02 |
0.0708 |
| 0.4 |
2.51 |
0.4910 |
0.0487 |
0.01040 |
2.83e-02 |
0.0691 |
| 0.5 |
3.16 |
0.4840 |
0.0460 |
0.01000 |
2.64e-02 |
0.0656 |
| 0.6 |
3.98 |
0.4610 |
0.0478 |
0.01040 |
2.75e-02 |
0.0682 |
| 0.7 |
5.01 |
0.4510 |
0.0455 |
0.01030 |
2.53e-02 |
0.0656 |
| 0.8 |
6.31 |
0.4420 |
0.0445 |
0.01030 |
2.43e-02 |
0.0646 |
| 0.9 |
7.94 |
0.4330 |
0.0457 |
0.01060 |
2.50e-02 |
0.0664 |
| 1.0 |
10.00 |
0.4270 |
0.0437 |
0.01040 |
2.34e-02 |
0.0641 |
| 1.1 |
12.60 |
0.3980 |
0.0464 |
0.01120 |
2.44e-02 |
0.0684 |
| 1.2 |
15.80 |
0.3890 |
0.0442 |
0.01100 |
2.27e-02 |
0.0658 |
| 1.3 |
20.00 |
0.3670 |
0.0434 |
0.01140 |
2.11e-02 |
0.0657 |
| 1.4 |
25.10 |
0.3420 |
0.0477 |
0.01260 |
2.31e-02 |
0.0724 |
| 1.5 |
31.60 |
0.3350 |
0.0426 |
0.01200 |
1.91e-02 |
0.0660 |
| 1.6 |
39.80 |
0.3190 |
0.0403 |
0.01220 |
1.65e-02 |
0.0642 |
| 1.7 |
50.10 |
0.3050 |
0.0440 |
0.01330 |
1.79e-02 |
0.0702 |
| 1.8 |
63.10 |
0.2740 |
0.0437 |
0.01400 |
1.63e-02 |
0.0711 |
| 1.9 |
79.40 |
0.2430 |
0.0480 |
0.01580 |
1.71e-02 |
0.0790 |
| 2.0 |
100.00 |
0.2340 |
0.0469 |
0.01610 |
1.53e-02 |
0.0785 |
| 2.1 |
126.00 |
0.2190 |
0.0486 |
0.01770 |
1.39e-02 |
0.0833 |
| 2.2 |
158.00 |
0.1910 |
0.0346 |
0.01550 |
4.31e-03 |
0.0649 |
| 2.3 |
200.00 |
0.1680 |
0.0391 |
0.01760 |
4.54e-03 |
0.0736 |
| 2.4 |
251.00 |
0.1510 |
0.0367 |
0.01870 |
4.15e-05 |
0.0734 |
| 2.5 |
316.00 |
0.1140 |
0.0398 |
0.02450 |
-8.27e-03 |
0.0879 |
| 2.6 |
398.00 |
0.1060 |
0.0438 |
0.02840 |
-1.18e-02 |
0.0994 |
| 2.7 |
501.00 |
0.0932 |
0.0758 |
0.06170 |
-4.51e-02 |
0.1970 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.122 |
0.157 |
-0.186 |
0.430 |
| 0.1 |
0.5320 |
1.26 |
0.154 |
0.202 |
-0.242 |
0.550 |
| 0.2 |
0.5230 |
1.58 |
0.160 |
0.201 |
-0.234 |
0.554 |
| 0.3 |
0.5060 |
2.00 |
0.160 |
0.206 |
-0.245 |
0.565 |
| 0.4 |
0.4910 |
2.51 |
0.170 |
0.204 |
-0.229 |
0.570 |
| 0.5 |
0.4840 |
3.16 |
0.201 |
0.196 |
-0.184 |
0.585 |
| 0.6 |
0.4610 |
3.98 |
0.201 |
0.202 |
-0.196 |
0.597 |
| 0.7 |
0.4510 |
5.01 |
0.225 |
0.199 |
-0.165 |
0.615 |
| 0.8 |
0.4420 |
6.31 |
0.232 |
0.199 |
-0.157 |
0.621 |
| 0.9 |
0.4330 |
7.94 |
0.232 |
0.203 |
-0.166 |
0.629 |
| 1.0 |
0.4270 |
10.00 |
0.232 |
0.200 |
-0.160 |
0.623 |
| 1.1 |
0.3980 |
12.60 |
0.232 |
0.213 |
-0.186 |
0.649 |
| 1.2 |
0.3890 |
15.80 |
0.232 |
0.209 |
-0.178 |
0.642 |
| 1.3 |
0.3670 |
20.00 |
0.232 |
0.215 |
-0.190 |
0.654 |
| 1.4 |
0.3420 |
25.10 |
0.232 |
0.234 |
-0.226 |
0.690 |
| 1.5 |
0.3350 |
31.60 |
0.257 |
0.223 |
-0.181 |
0.694 |
| 1.6 |
0.3190 |
39.80 |
0.257 |
0.226 |
-0.186 |
0.700 |
| 1.7 |
0.3050 |
50.10 |
0.257 |
0.245 |
-0.223 |
0.736 |
| 1.8 |
0.2740 |
63.10 |
0.257 |
0.255 |
-0.243 |
0.756 |
| 1.9 |
0.2430 |
79.40 |
0.257 |
0.284 |
-0.300 |
0.813 |
| 2.0 |
0.2340 |
100.00 |
0.257 |
0.289 |
-0.310 |
0.824 |
| 2.1 |
0.2190 |
126.00 |
0.257 |
0.315 |
-0.361 |
0.874 |
| 2.2 |
0.1910 |
158.00 |
0.257 |
0.279 |
-0.289 |
0.803 |
| 2.3 |
0.1680 |
200.00 |
0.257 |
0.314 |
-0.358 |
0.871 |
| 2.4 |
0.1510 |
251.00 |
0.257 |
0.331 |
-0.393 |
0.906 |
| 2.5 |
0.1140 |
316.00 |
0.257 |
0.428 |
-0.582 |
1.100 |
| 2.6 |
0.1060 |
398.00 |
0.257 |
0.492 |
-0.707 |
1.220 |
| 2.7 |
0.0932 |
501.00 |
0.257 |
1.060 |
-1.810 |
2.330 |
IgG3 V1V2 C.1086-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.0515 |
0.00678 |
0.038200 |
0.0648 |
| 0.1 |
0.8460 |
1.26 |
0.0483 |
0.00778 |
0.033100 |
0.0636 |
| 0.2 |
0.8440 |
1.58 |
0.0483 |
0.00782 |
0.033000 |
0.0636 |
| 0.3 |
0.8440 |
2.00 |
0.0483 |
0.00782 |
0.033000 |
0.0636 |
| 0.4 |
0.8380 |
2.51 |
0.0483 |
0.00783 |
0.033000 |
0.0637 |
| 0.5 |
0.8350 |
3.16 |
0.0483 |
0.00789 |
0.032900 |
0.0638 |
| 0.6 |
0.8280 |
3.98 |
0.0483 |
0.00777 |
0.033100 |
0.0635 |
| 0.7 |
0.8200 |
5.01 |
0.0483 |
0.00780 |
0.033000 |
0.0636 |
| 0.8 |
0.8030 |
6.31 |
0.0483 |
0.00788 |
0.032900 |
0.0638 |
| 0.9 |
0.7830 |
7.94 |
0.0483 |
0.00812 |
0.032400 |
0.0642 |
| 1.0 |
0.7750 |
10.00 |
0.0483 |
0.00818 |
0.032300 |
0.0643 |
| 1.1 |
0.7610 |
12.60 |
0.0483 |
0.00835 |
0.031900 |
0.0647 |
| 1.2 |
0.7430 |
15.80 |
0.0483 |
0.00826 |
0.032100 |
0.0645 |
| 1.3 |
0.7250 |
20.00 |
0.0483 |
0.00829 |
0.032100 |
0.0646 |
| 1.4 |
0.7020 |
25.10 |
0.0483 |
0.00850 |
0.031600 |
0.0650 |
| 1.5 |
0.6710 |
31.60 |
0.0483 |
0.00848 |
0.031700 |
0.0649 |
| 1.6 |
0.6690 |
39.80 |
0.0483 |
0.00852 |
0.031600 |
0.0650 |
| 1.7 |
0.6400 |
50.10 |
0.0483 |
0.00886 |
0.030900 |
0.0657 |
| 1.8 |
0.6190 |
63.10 |
0.0483 |
0.00912 |
0.030400 |
0.0662 |
| 1.9 |
0.5880 |
79.40 |
0.0483 |
0.00956 |
0.029600 |
0.0671 |
| 2.0 |
0.5710 |
100.00 |
0.0483 |
0.00942 |
0.029800 |
0.0668 |
| 2.1 |
0.5480 |
126.00 |
0.0483 |
0.00981 |
0.029100 |
0.0675 |
| 2.2 |
0.4890 |
158.00 |
0.0483 |
0.01020 |
0.028400 |
0.0682 |
| 2.3 |
0.4610 |
200.00 |
0.0483 |
0.01080 |
0.027100 |
0.0695 |
| 2.4 |
0.4200 |
251.00 |
0.0483 |
0.01180 |
0.025200 |
0.0714 |
| 2.5 |
0.3670 |
316.00 |
0.0483 |
0.01310 |
0.022700 |
0.0739 |
| 2.6 |
0.3540 |
398.00 |
0.0483 |
0.01300 |
0.022900 |
0.0738 |
| 2.7 |
0.2920 |
501.00 |
0.0483 |
0.01470 |
0.019500 |
0.0771 |
| 2.8 |
0.2620 |
631.00 |
0.0483 |
0.01700 |
0.015100 |
0.0816 |
| 2.9 |
0.2270 |
794.00 |
0.0483 |
0.01670 |
0.015500 |
0.0811 |
| 3.0 |
0.1980 |
1000.00 |
0.0481 |
0.01810 |
0.012600 |
0.0837 |
| 3.1 |
0.1810 |
1260.00 |
0.0481 |
0.01880 |
0.011300 |
0.0849 |
| 3.2 |
0.1470 |
1580.00 |
0.0481 |
0.02040 |
0.008050 |
0.0882 |
| 3.3 |
0.1420 |
2000.00 |
0.0481 |
0.02120 |
0.006610 |
0.0897 |
| 3.4 |
0.0954 |
2510.00 |
0.0481 |
0.05340 |
-0.056600 |
0.1530 |
| 3.5 |
0.0944 |
3160.00 |
0.0341 |
0.01730 |
0.000118 |
0.0680 |
| 3.6 |
0.0741 |
3980.00 |
0.0341 |
0.02090 |
-0.006910 |
0.0750 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.0515 |
0.00678 |
0.03570 |
0.0650 |
| 0.1 |
1.26 |
0.8460 |
0.0469 |
0.00778 |
0.03170 |
0.0622 |
| 0.2 |
1.58 |
0.8440 |
0.0471 |
0.00782 |
0.03180 |
0.0625 |
| 0.3 |
2.00 |
0.8440 |
0.0471 |
0.00782 |
0.03180 |
0.0625 |
| 0.4 |
2.51 |
0.8380 |
0.0472 |
0.00783 |
0.03190 |
0.0626 |
| 0.5 |
3.16 |
0.8350 |
0.0476 |
0.00789 |
0.03210 |
0.0630 |
| 0.6 |
3.98 |
0.8280 |
0.0457 |
0.00777 |
0.03050 |
0.0610 |
| 0.7 |
5.01 |
0.8200 |
0.0459 |
0.00780 |
0.03070 |
0.0612 |
| 0.8 |
6.31 |
0.8030 |
0.0459 |
0.00788 |
0.03050 |
0.0614 |
| 0.9 |
7.94 |
0.7830 |
0.0473 |
0.00812 |
0.03140 |
0.0632 |
| 1.0 |
10.00 |
0.7750 |
0.0476 |
0.00818 |
0.03160 |
0.0636 |
| 1.1 |
12.60 |
0.7610 |
0.0485 |
0.00835 |
0.03220 |
0.0649 |
| 1.2 |
15.80 |
0.7430 |
0.0467 |
0.00826 |
0.03050 |
0.0629 |
| 1.3 |
20.00 |
0.7250 |
0.0463 |
0.00829 |
0.03010 |
0.0626 |
| 1.4 |
25.10 |
0.7020 |
0.0475 |
0.00850 |
0.03080 |
0.0641 |
| 1.5 |
31.60 |
0.6710 |
0.0453 |
0.00848 |
0.02870 |
0.0619 |
| 1.6 |
39.80 |
0.6690 |
0.0455 |
0.00852 |
0.02880 |
0.0622 |
| 1.7 |
50.10 |
0.6400 |
0.0466 |
0.00886 |
0.02920 |
0.0639 |
| 1.8 |
63.10 |
0.6190 |
0.0476 |
0.00912 |
0.02980 |
0.0655 |
| 1.9 |
79.40 |
0.5880 |
0.0500 |
0.00956 |
0.03120 |
0.0687 |
| 2.0 |
100.00 |
0.5710 |
0.0470 |
0.00942 |
0.02850 |
0.0654 |
| 2.1 |
126.00 |
0.5480 |
0.0489 |
0.00981 |
0.02970 |
0.0681 |
| 2.2 |
158.00 |
0.4890 |
0.0470 |
0.01020 |
0.02710 |
0.0669 |
| 2.3 |
200.00 |
0.4610 |
0.0497 |
0.01080 |
0.02850 |
0.0708 |
| 2.4 |
251.00 |
0.4200 |
0.0529 |
0.01180 |
0.02970 |
0.0760 |
| 2.5 |
316.00 |
0.3670 |
0.0567 |
0.01310 |
0.03110 |
0.0823 |
| 2.6 |
398.00 |
0.3540 |
0.0535 |
0.01300 |
0.02800 |
0.0789 |
| 2.7 |
501.00 |
0.2920 |
0.0525 |
0.01470 |
0.02380 |
0.0813 |
| 2.8 |
631.00 |
0.2620 |
0.0598 |
0.01700 |
0.02660 |
0.0931 |
| 2.9 |
794.00 |
0.2270 |
0.0550 |
0.01670 |
0.02220 |
0.0877 |
| 3.0 |
1000.00 |
0.1980 |
0.0481 |
0.01810 |
0.01250 |
0.0837 |
| 3.1 |
1260.00 |
0.1810 |
0.0453 |
0.01880 |
0.00852 |
0.0821 |
| 3.2 |
1580.00 |
0.1470 |
0.0428 |
0.02040 |
0.00269 |
0.0828 |
| 3.3 |
2000.00 |
0.1420 |
0.0443 |
0.02120 |
0.00274 |
0.0858 |
| 3.4 |
2510.00 |
0.0954 |
0.0830 |
0.05340 |
-0.02170 |
0.1880 |
| 3.5 |
3160.00 |
0.0944 |
0.0318 |
0.01730 |
-0.00211 |
0.0658 |
| 3.6 |
3980.00 |
0.0741 |
0.0363 |
0.02090 |
-0.00467 |
0.0773 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.122 |
0.157 |
-0.186 |
0.430 |
| 0.1 |
0.8460 |
1.26 |
0.177 |
0.166 |
-0.149 |
0.502 |
| 0.2 |
0.8440 |
1.58 |
0.177 |
0.167 |
-0.150 |
0.503 |
| 0.3 |
0.8440 |
2.00 |
0.177 |
0.167 |
-0.150 |
0.503 |
| 0.4 |
0.8380 |
2.51 |
0.177 |
0.167 |
-0.150 |
0.504 |
| 0.5 |
0.8350 |
3.16 |
0.177 |
0.167 |
-0.151 |
0.505 |
| 0.6 |
0.8280 |
3.98 |
0.177 |
0.166 |
-0.148 |
0.502 |
| 0.7 |
0.8200 |
5.01 |
0.177 |
0.166 |
-0.149 |
0.503 |
| 0.8 |
0.8030 |
6.31 |
0.177 |
0.167 |
-0.151 |
0.505 |
| 0.9 |
0.7830 |
7.94 |
0.177 |
0.171 |
-0.158 |
0.511 |
| 1.0 |
0.7750 |
10.00 |
0.177 |
0.171 |
-0.159 |
0.513 |
| 1.1 |
0.7610 |
12.60 |
0.177 |
0.174 |
-0.164 |
0.518 |
| 1.2 |
0.7430 |
15.80 |
0.177 |
0.173 |
-0.161 |
0.515 |
| 1.3 |
0.7250 |
20.00 |
0.177 |
0.173 |
-0.162 |
0.516 |
| 1.4 |
0.7020 |
25.10 |
0.177 |
0.176 |
-0.168 |
0.522 |
| 1.5 |
0.6710 |
31.60 |
0.177 |
0.176 |
-0.168 |
0.521 |
| 1.6 |
0.6690 |
39.80 |
0.177 |
0.176 |
-0.169 |
0.522 |
| 1.7 |
0.6400 |
50.10 |
0.177 |
0.181 |
-0.178 |
0.532 |
| 1.8 |
0.6190 |
63.10 |
0.177 |
0.185 |
-0.185 |
0.539 |
| 1.9 |
0.5880 |
79.40 |
0.177 |
0.191 |
-0.198 |
0.552 |
| 2.0 |
0.5710 |
100.00 |
0.177 |
0.189 |
-0.194 |
0.548 |
| 2.1 |
0.5480 |
126.00 |
0.177 |
0.195 |
-0.205 |
0.558 |
| 2.2 |
0.4890 |
158.00 |
0.177 |
0.200 |
-0.215 |
0.569 |
| 2.3 |
0.4610 |
200.00 |
0.177 |
0.209 |
-0.234 |
0.587 |
| 2.4 |
0.4200 |
251.00 |
0.177 |
0.225 |
-0.263 |
0.617 |
| 2.5 |
0.3670 |
316.00 |
0.177 |
0.244 |
-0.302 |
0.656 |
| 2.6 |
0.3540 |
398.00 |
0.177 |
0.243 |
-0.299 |
0.653 |
| 2.7 |
0.2920 |
501.00 |
0.177 |
0.269 |
-0.351 |
0.705 |
| 2.8 |
0.2620 |
631.00 |
0.177 |
0.306 |
-0.423 |
0.776 |
| 2.9 |
0.2270 |
794.00 |
0.177 |
0.302 |
-0.415 |
0.768 |
| 3.0 |
0.1980 |
1000.00 |
0.180 |
0.325 |
-0.457 |
0.816 |
| 3.1 |
0.1810 |
1260.00 |
0.180 |
0.335 |
-0.477 |
0.837 |
| 3.2 |
0.1470 |
1580.00 |
0.180 |
0.362 |
-0.531 |
0.890 |
| 3.3 |
0.1420 |
2000.00 |
0.180 |
0.375 |
-0.554 |
0.914 |
| 3.4 |
0.0954 |
2510.00 |
0.180 |
0.916 |
-1.620 |
1.970 |
| 3.5 |
0.0944 |
3160.00 |
0.419 |
0.304 |
-0.175 |
1.010 |
| 3.6 |
0.0741 |
3980.00 |
0.419 |
0.363 |
-0.292 |
1.130 |
HVTN 702
- Adjustment covariates: AGELE25, RSCORCAT
- Event time variable: HIV6.5_24FU
- Event type variable: HIV6.5_24
- Weight variable: SAMPWT
- Reference timepoint: 552 days
- All learners: GLM
IgG V1V2 B.CaseA-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.136 |
0.0122 |
0.11200 |
0.160 |
| 0.1 |
0.6080 |
1.26 |
0.136 |
0.0309 |
0.07560 |
0.197 |
| 0.2 |
0.6080 |
1.58 |
0.136 |
0.0309 |
0.07560 |
0.197 |
| 0.3 |
0.6080 |
2.00 |
0.136 |
0.0309 |
0.07560 |
0.197 |
| 0.4 |
0.5870 |
2.51 |
0.136 |
0.0331 |
0.07150 |
0.201 |
| 0.5 |
0.5870 |
3.16 |
0.136 |
0.0331 |
0.07150 |
0.201 |
| 0.6 |
0.5870 |
3.98 |
0.136 |
0.0331 |
0.07150 |
0.201 |
| 0.7 |
0.5870 |
5.01 |
0.136 |
0.0331 |
0.07150 |
0.201 |
| 0.8 |
0.5870 |
6.31 |
0.136 |
0.0331 |
0.07150 |
0.201 |
| 0.9 |
0.5460 |
7.94 |
0.136 |
0.0312 |
0.07520 |
0.197 |
| 1.0 |
0.5460 |
10.00 |
0.136 |
0.0312 |
0.07520 |
0.197 |
| 1.1 |
0.5460 |
12.60 |
0.136 |
0.0312 |
0.07520 |
0.197 |
| 1.2 |
0.5460 |
15.80 |
0.136 |
0.0312 |
0.07520 |
0.197 |
| 1.3 |
0.5100 |
20.00 |
0.136 |
0.0313 |
0.07500 |
0.198 |
| 1.4 |
0.4850 |
25.10 |
0.136 |
0.0305 |
0.07650 |
0.196 |
| 1.5 |
0.4840 |
31.60 |
0.136 |
0.0302 |
0.07710 |
0.195 |
| 1.6 |
0.4820 |
39.80 |
0.136 |
0.0299 |
0.07770 |
0.195 |
| 1.7 |
0.4800 |
50.10 |
0.136 |
0.0295 |
0.07840 |
0.194 |
| 1.8 |
0.4560 |
63.10 |
0.136 |
0.0291 |
0.07920 |
0.193 |
| 1.9 |
0.4380 |
79.40 |
0.136 |
0.0300 |
0.07740 |
0.195 |
| 2.0 |
0.4120 |
100.00 |
0.136 |
0.0317 |
0.07420 |
0.198 |
| 2.1 |
0.3840 |
126.00 |
0.136 |
0.0348 |
0.06810 |
0.204 |
| 2.2 |
0.3580 |
158.00 |
0.136 |
0.0399 |
0.05810 |
0.215 |
| 2.3 |
0.3400 |
200.00 |
0.136 |
0.0373 |
0.06320 |
0.209 |
| 2.4 |
0.3080 |
251.00 |
0.136 |
0.0357 |
0.06630 |
0.206 |
| 2.5 |
0.3080 |
316.00 |
0.136 |
0.0357 |
0.06630 |
0.206 |
| 2.6 |
0.2700 |
398.00 |
0.136 |
0.0350 |
0.06760 |
0.205 |
| 2.7 |
0.2040 |
501.00 |
0.136 |
0.0423 |
0.05330 |
0.219 |
| 2.8 |
0.1480 |
631.00 |
0.136 |
0.0689 |
0.00121 |
0.271 |
| 2.9 |
0.1310 |
794.00 |
0.136 |
0.0800 |
-0.02040 |
0.293 |
| 3.0 |
0.1300 |
1000.00 |
0.136 |
0.0786 |
-0.01780 |
0.290 |
| 3.1 |
0.0964 |
1260.00 |
0.136 |
0.1030 |
-0.06500 |
0.338 |
| 3.2 |
0.0704 |
1580.00 |
0.136 |
0.1540 |
-0.16500 |
0.437 |
| 3.3 |
0.0635 |
2000.00 |
0.136 |
0.1490 |
-0.15500 |
0.428 |
| 3.4 |
0.0618 |
2510.00 |
0.136 |
0.1560 |
-0.16900 |
0.442 |
| 3.5 |
0.0512 |
3160.00 |
0.136 |
0.1600 |
-0.17600 |
0.449 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.0952 |
0.0122 |
0.0636 |
0.129 |
| 0.1 |
1.26 |
0.6080 |
0.1300 |
0.0309 |
0.0692 |
0.191 |
| 0.2 |
1.58 |
0.6080 |
0.1300 |
0.0309 |
0.0692 |
0.191 |
| 0.3 |
2.00 |
0.6080 |
0.1300 |
0.0309 |
0.0692 |
0.191 |
| 0.4 |
2.51 |
0.5870 |
0.1360 |
0.0331 |
0.0712 |
0.201 |
| 0.5 |
3.16 |
0.5870 |
0.1360 |
0.0331 |
0.0712 |
0.201 |
| 0.6 |
3.98 |
0.5870 |
0.1360 |
0.0331 |
0.0712 |
0.201 |
| 0.7 |
5.01 |
0.5870 |
0.1360 |
0.0331 |
0.0712 |
0.201 |
| 0.8 |
6.31 |
0.5870 |
0.1360 |
0.0331 |
0.0712 |
0.201 |
| 0.9 |
7.94 |
0.5460 |
0.1330 |
0.0312 |
0.0722 |
0.194 |
| 1.0 |
10.00 |
0.5460 |
0.1330 |
0.0312 |
0.0722 |
0.194 |
| 1.1 |
12.60 |
0.5460 |
0.1330 |
0.0312 |
0.0722 |
0.194 |
| 1.2 |
15.80 |
0.5460 |
0.1330 |
0.0312 |
0.0722 |
0.194 |
| 1.3 |
20.00 |
0.5100 |
0.1360 |
0.0313 |
0.0751 |
0.198 |
| 1.4 |
25.10 |
0.4850 |
0.1340 |
0.0305 |
0.0747 |
0.194 |
| 1.5 |
31.60 |
0.4840 |
0.1320 |
0.0302 |
0.0726 |
0.191 |
| 1.6 |
39.80 |
0.4820 |
0.1290 |
0.0299 |
0.0707 |
0.188 |
| 1.7 |
50.10 |
0.4800 |
0.1270 |
0.0295 |
0.0687 |
0.184 |
| 1.8 |
63.10 |
0.4560 |
0.1240 |
0.0291 |
0.0670 |
0.181 |
| 1.9 |
79.40 |
0.4380 |
0.1240 |
0.0300 |
0.0650 |
0.183 |
| 2.0 |
100.00 |
0.4120 |
0.1240 |
0.0317 |
0.0618 |
0.186 |
| 2.1 |
126.00 |
0.3840 |
0.1270 |
0.0348 |
0.0589 |
0.195 |
| 2.2 |
158.00 |
0.3580 |
0.1360 |
0.0399 |
0.0580 |
0.214 |
| 2.3 |
200.00 |
0.3400 |
0.1190 |
0.0373 |
0.0456 |
0.192 |
| 2.4 |
251.00 |
0.3080 |
0.1090 |
0.0357 |
0.0391 |
0.179 |
| 2.5 |
316.00 |
0.3080 |
0.1090 |
0.0357 |
0.0391 |
0.179 |
| 2.6 |
398.00 |
0.2700 |
0.1020 |
0.0350 |
0.0329 |
0.170 |
| 2.7 |
501.00 |
0.2040 |
0.1130 |
0.0423 |
0.0305 |
0.196 |
| 2.8 |
631.00 |
0.1480 |
0.1900 |
0.0689 |
0.0546 |
0.325 |
| 2.9 |
794.00 |
0.1310 |
0.2140 |
0.0800 |
0.0572 |
0.371 |
| 3.0 |
1000.00 |
0.1300 |
0.2020 |
0.0786 |
0.0475 |
0.356 |
| 3.1 |
1260.00 |
0.0964 |
0.4160 |
0.1030 |
0.2150 |
0.617 |
| 3.2 |
1580.00 |
0.0704 |
0.6290 |
0.1540 |
0.3280 |
0.930 |
| 3.3 |
2000.00 |
0.0635 |
0.5310 |
0.1490 |
0.2400 |
0.823 |
| 3.4 |
2510.00 |
0.0618 |
0.5070 |
0.1560 |
0.2010 |
0.813 |
| 3.5 |
3160.00 |
0.0512 |
0.4990 |
0.1600 |
0.1860 |
0.811 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
-0.656 |
0.276 |
-1.20 |
-0.114 |
| 0.1 |
0.6080 |
1.26 |
-0.656 |
0.442 |
-1.52 |
0.212 |
| 0.2 |
0.6080 |
1.58 |
-0.656 |
0.442 |
-1.52 |
0.212 |
| 0.3 |
0.6080 |
2.00 |
-0.656 |
0.442 |
-1.52 |
0.212 |
| 0.4 |
0.5870 |
2.51 |
-0.656 |
0.464 |
-1.57 |
0.255 |
| 0.5 |
0.5870 |
3.16 |
-0.656 |
0.464 |
-1.57 |
0.255 |
| 0.6 |
0.5870 |
3.98 |
-0.656 |
0.464 |
-1.57 |
0.255 |
| 0.7 |
0.5870 |
5.01 |
-0.656 |
0.464 |
-1.57 |
0.255 |
| 0.8 |
0.5870 |
6.31 |
-0.656 |
0.464 |
-1.57 |
0.255 |
| 0.9 |
0.5460 |
7.94 |
-0.656 |
0.445 |
-1.53 |
0.217 |
| 1.0 |
0.5460 |
10.00 |
-0.656 |
0.445 |
-1.53 |
0.217 |
| 1.1 |
0.5460 |
12.60 |
-0.656 |
0.445 |
-1.53 |
0.217 |
| 1.2 |
0.5460 |
15.80 |
-0.656 |
0.445 |
-1.53 |
0.217 |
| 1.3 |
0.5100 |
20.00 |
-0.656 |
0.446 |
-1.53 |
0.218 |
| 1.4 |
0.4850 |
25.10 |
-0.656 |
0.438 |
-1.51 |
0.203 |
| 1.5 |
0.4840 |
31.60 |
-0.656 |
0.435 |
-1.51 |
0.197 |
| 1.6 |
0.4820 |
39.80 |
-0.656 |
0.432 |
-1.50 |
0.190 |
| 1.7 |
0.4800 |
50.10 |
-0.656 |
0.428 |
-1.49 |
0.183 |
| 1.8 |
0.4560 |
63.10 |
-0.656 |
0.424 |
-1.49 |
0.175 |
| 1.9 |
0.4380 |
79.40 |
-0.656 |
0.433 |
-1.50 |
0.193 |
| 2.0 |
0.4120 |
100.00 |
-0.656 |
0.450 |
-1.54 |
0.227 |
| 2.1 |
0.3840 |
126.00 |
-0.656 |
0.483 |
-1.60 |
0.290 |
| 2.2 |
0.3580 |
158.00 |
-0.656 |
0.538 |
-1.71 |
0.399 |
| 2.3 |
0.3400 |
200.00 |
-0.656 |
0.509 |
-1.65 |
0.343 |
| 2.4 |
0.3080 |
251.00 |
-0.656 |
0.493 |
-1.62 |
0.310 |
| 2.5 |
0.3080 |
316.00 |
-0.656 |
0.493 |
-1.62 |
0.310 |
| 2.6 |
0.2700 |
398.00 |
-0.656 |
0.485 |
-1.61 |
0.296 |
| 2.7 |
0.2040 |
501.00 |
-0.656 |
0.565 |
-1.76 |
0.451 |
| 2.8 |
0.1480 |
631.00 |
-0.656 |
0.869 |
-2.36 |
1.050 |
| 2.9 |
0.1310 |
794.00 |
-0.656 |
0.999 |
-2.61 |
1.300 |
| 3.0 |
0.1300 |
1000.00 |
-0.656 |
0.983 |
-2.58 |
1.270 |
| 3.1 |
0.0964 |
1260.00 |
-0.656 |
1.270 |
-3.14 |
1.830 |
| 3.2 |
0.0704 |
1580.00 |
-0.656 |
1.880 |
-4.34 |
3.030 |
| 3.3 |
0.0635 |
2000.00 |
-0.656 |
1.820 |
-4.23 |
2.920 |
| 3.4 |
0.0618 |
2510.00 |
-0.656 |
1.910 |
-4.40 |
3.090 |
| 3.5 |
0.0512 |
3160.00 |
-0.656 |
1.950 |
-4.48 |
3.170 |
IgG V1V2 C.1086-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.0990 |
0.0122 |
0.07510 |
0.123 |
| 0.1 |
0.9840 |
1.26 |
0.0990 |
0.0165 |
0.06660 |
0.131 |
| 0.2 |
0.9840 |
1.58 |
0.0990 |
0.0165 |
0.06660 |
0.131 |
| 0.3 |
0.9840 |
2.00 |
0.0990 |
0.0165 |
0.06660 |
0.131 |
| 0.4 |
0.9840 |
2.51 |
0.0990 |
0.0165 |
0.06660 |
0.131 |
| 0.5 |
0.9840 |
3.16 |
0.0990 |
0.0165 |
0.06660 |
0.131 |
| 0.6 |
0.9840 |
3.98 |
0.0990 |
0.0165 |
0.06660 |
0.131 |
| 0.7 |
0.9840 |
5.01 |
0.0990 |
0.0165 |
0.06660 |
0.131 |
| 0.8 |
0.9840 |
6.31 |
0.0990 |
0.0165 |
0.06660 |
0.131 |
| 0.9 |
0.9840 |
7.94 |
0.0990 |
0.0165 |
0.06660 |
0.131 |
| 1.0 |
0.9840 |
10.00 |
0.0990 |
0.0165 |
0.06660 |
0.131 |
| 1.1 |
0.9700 |
12.60 |
0.0990 |
0.0170 |
0.06570 |
0.132 |
| 1.2 |
0.9700 |
15.80 |
0.0990 |
0.0170 |
0.06570 |
0.132 |
| 1.3 |
0.9700 |
20.00 |
0.0990 |
0.0170 |
0.06570 |
0.132 |
| 1.4 |
0.9700 |
25.10 |
0.0990 |
0.0170 |
0.06570 |
0.132 |
| 1.5 |
0.9680 |
31.60 |
0.0990 |
0.0168 |
0.06600 |
0.132 |
| 1.6 |
0.9580 |
39.80 |
0.0990 |
0.0169 |
0.06590 |
0.132 |
| 1.7 |
0.9410 |
50.10 |
0.0990 |
0.0168 |
0.06600 |
0.132 |
| 1.8 |
0.9410 |
63.10 |
0.0990 |
0.0168 |
0.06600 |
0.132 |
| 1.9 |
0.9400 |
79.40 |
0.0990 |
0.0166 |
0.06640 |
0.132 |
| 2.0 |
0.9400 |
100.00 |
0.0990 |
0.0166 |
0.06640 |
0.132 |
| 2.1 |
0.9380 |
126.00 |
0.0990 |
0.0167 |
0.06630 |
0.132 |
| 2.2 |
0.8780 |
158.00 |
0.0990 |
0.0179 |
0.06380 |
0.134 |
| 2.3 |
0.8760 |
200.00 |
0.0990 |
0.0178 |
0.06410 |
0.134 |
| 2.4 |
0.8760 |
251.00 |
0.0990 |
0.0178 |
0.06410 |
0.134 |
| 2.5 |
0.8710 |
316.00 |
0.0990 |
0.0172 |
0.06530 |
0.133 |
| 2.6 |
0.8320 |
398.00 |
0.0990 |
0.0179 |
0.06400 |
0.134 |
| 2.7 |
0.7830 |
501.00 |
0.0990 |
0.0198 |
0.06010 |
0.138 |
| 2.8 |
0.7360 |
631.00 |
0.0990 |
0.0209 |
0.05810 |
0.140 |
| 2.9 |
0.6600 |
794.00 |
0.0990 |
0.0222 |
0.05550 |
0.142 |
| 3.0 |
0.6200 |
1000.00 |
0.0990 |
0.0236 |
0.05270 |
0.145 |
| 3.1 |
0.5880 |
1260.00 |
0.0990 |
0.0225 |
0.05490 |
0.143 |
| 3.2 |
0.5130 |
1580.00 |
0.0990 |
0.0268 |
0.04650 |
0.151 |
| 3.3 |
0.4550 |
2000.00 |
0.0990 |
0.0304 |
0.03930 |
0.159 |
| 3.4 |
0.3850 |
2510.00 |
0.0990 |
0.0313 |
0.03760 |
0.160 |
| 3.5 |
0.3240 |
3160.00 |
0.0990 |
0.0346 |
0.03110 |
0.167 |
| 3.6 |
0.2410 |
3980.00 |
0.0990 |
0.0610 |
-0.02060 |
0.219 |
| 3.7 |
0.1950 |
5010.00 |
0.0990 |
0.0571 |
-0.01300 |
0.211 |
| 3.8 |
0.1770 |
6310.00 |
0.0990 |
0.0521 |
-0.00310 |
0.201 |
| 3.9 |
0.1680 |
7940.00 |
0.0990 |
0.0457 |
0.00948 |
0.188 |
| 4.0 |
0.1260 |
10000.00 |
0.0990 |
0.0568 |
-0.01230 |
0.210 |
| 4.1 |
0.1220 |
12600.00 |
0.0990 |
0.0558 |
-0.01030 |
0.208 |
| 4.2 |
0.1060 |
15800.00 |
0.0990 |
0.0519 |
-0.00284 |
0.201 |
| 4.3 |
0.0878 |
20000.00 |
0.0917 |
0.0484 |
-0.00310 |
0.187 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.0952 |
0.0122 |
0.0636 |
0.129 |
| 0.1 |
1.26 |
0.9840 |
0.0935 |
0.0165 |
0.0611 |
0.126 |
| 0.2 |
1.58 |
0.9840 |
0.0935 |
0.0165 |
0.0611 |
0.126 |
| 0.3 |
2.00 |
0.9840 |
0.0935 |
0.0165 |
0.0611 |
0.126 |
| 0.4 |
2.51 |
0.9840 |
0.0935 |
0.0165 |
0.0611 |
0.126 |
| 0.5 |
3.16 |
0.9840 |
0.0935 |
0.0165 |
0.0611 |
0.126 |
| 0.6 |
3.98 |
0.9840 |
0.0935 |
0.0165 |
0.0611 |
0.126 |
| 0.7 |
5.01 |
0.9840 |
0.0935 |
0.0165 |
0.0611 |
0.126 |
| 0.8 |
6.31 |
0.9840 |
0.0935 |
0.0165 |
0.0611 |
0.126 |
| 0.9 |
7.94 |
0.9840 |
0.0935 |
0.0165 |
0.0611 |
0.126 |
| 1.0 |
10.00 |
0.9840 |
0.0935 |
0.0165 |
0.0611 |
0.126 |
| 1.1 |
12.60 |
0.9700 |
0.0959 |
0.0170 |
0.0626 |
0.129 |
| 1.2 |
15.80 |
0.9700 |
0.0959 |
0.0170 |
0.0626 |
0.129 |
| 1.3 |
20.00 |
0.9700 |
0.0959 |
0.0170 |
0.0626 |
0.129 |
| 1.4 |
25.10 |
0.9700 |
0.0959 |
0.0170 |
0.0626 |
0.129 |
| 1.5 |
31.60 |
0.9680 |
0.0943 |
0.0168 |
0.0614 |
0.127 |
| 1.6 |
39.80 |
0.9580 |
0.0947 |
0.0169 |
0.0615 |
0.128 |
| 1.7 |
50.10 |
0.9410 |
0.0936 |
0.0168 |
0.0606 |
0.127 |
| 1.8 |
63.10 |
0.9410 |
0.0936 |
0.0168 |
0.0606 |
0.127 |
| 1.9 |
79.40 |
0.9400 |
0.0918 |
0.0166 |
0.0593 |
0.124 |
| 2.0 |
100.00 |
0.9400 |
0.0918 |
0.0166 |
0.0593 |
0.124 |
| 2.1 |
126.00 |
0.9380 |
0.0922 |
0.0167 |
0.0595 |
0.125 |
| 2.2 |
158.00 |
0.8780 |
0.0976 |
0.0179 |
0.0624 |
0.133 |
| 2.3 |
200.00 |
0.8760 |
0.0960 |
0.0178 |
0.0612 |
0.131 |
| 2.4 |
251.00 |
0.8760 |
0.0960 |
0.0178 |
0.0612 |
0.131 |
| 2.5 |
316.00 |
0.8710 |
0.0906 |
0.0172 |
0.0570 |
0.124 |
| 2.6 |
398.00 |
0.8320 |
0.0928 |
0.0179 |
0.0578 |
0.128 |
| 2.7 |
501.00 |
0.7830 |
0.0986 |
0.0198 |
0.0598 |
0.137 |
| 2.8 |
631.00 |
0.7360 |
0.0978 |
0.0209 |
0.0569 |
0.139 |
| 2.9 |
794.00 |
0.6600 |
0.1000 |
0.0222 |
0.0567 |
0.144 |
| 3.0 |
1000.00 |
0.6200 |
0.1020 |
0.0236 |
0.0555 |
0.148 |
| 3.1 |
1260.00 |
0.5880 |
0.0916 |
0.0225 |
0.0475 |
0.136 |
| 3.2 |
1580.00 |
0.5130 |
0.1020 |
0.0268 |
0.0491 |
0.154 |
| 3.3 |
2000.00 |
0.4550 |
0.1150 |
0.0304 |
0.0555 |
0.175 |
| 3.4 |
2510.00 |
0.3850 |
0.1200 |
0.0313 |
0.0582 |
0.181 |
| 3.5 |
3160.00 |
0.3240 |
0.1180 |
0.0346 |
0.0499 |
0.186 |
| 3.6 |
3980.00 |
0.2410 |
0.1710 |
0.0610 |
0.0512 |
0.290 |
| 3.7 |
5010.00 |
0.1950 |
0.1600 |
0.0571 |
0.0482 |
0.272 |
| 3.8 |
6310.00 |
0.1770 |
0.1430 |
0.0521 |
0.0413 |
0.245 |
| 3.9 |
7940.00 |
0.1680 |
0.1100 |
0.0457 |
0.0204 |
0.199 |
| 4.0 |
10000.00 |
0.1260 |
0.1350 |
0.0568 |
0.0241 |
0.247 |
| 4.1 |
12600.00 |
0.1220 |
0.1260 |
0.0558 |
0.0167 |
0.235 |
| 4.2 |
15800.00 |
0.1060 |
0.1160 |
0.0519 |
0.0137 |
0.217 |
| 4.3 |
20000.00 |
0.0878 |
0.0917 |
0.0484 |
-0.0031 |
0.187 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
-0.202 |
0.225 |
-0.643 |
0.239 |
| 0.1 |
0.9840 |
1.26 |
-0.202 |
0.263 |
-0.717 |
0.312 |
| 0.2 |
0.9840 |
1.58 |
-0.202 |
0.263 |
-0.717 |
0.312 |
| 0.3 |
0.9840 |
2.00 |
-0.202 |
0.263 |
-0.717 |
0.312 |
| 0.4 |
0.9840 |
2.51 |
-0.202 |
0.263 |
-0.717 |
0.312 |
| 0.5 |
0.9840 |
3.16 |
-0.202 |
0.263 |
-0.717 |
0.312 |
| 0.6 |
0.9840 |
3.98 |
-0.202 |
0.263 |
-0.717 |
0.312 |
| 0.7 |
0.9840 |
5.01 |
-0.202 |
0.263 |
-0.717 |
0.312 |
| 0.8 |
0.9840 |
6.31 |
-0.202 |
0.263 |
-0.717 |
0.312 |
| 0.9 |
0.9840 |
7.94 |
-0.202 |
0.263 |
-0.717 |
0.312 |
| 1.0 |
0.9840 |
10.00 |
-0.202 |
0.263 |
-0.717 |
0.312 |
| 1.1 |
0.9700 |
12.60 |
-0.202 |
0.267 |
-0.726 |
0.321 |
| 1.2 |
0.9700 |
15.80 |
-0.202 |
0.267 |
-0.726 |
0.321 |
| 1.3 |
0.9700 |
20.00 |
-0.202 |
0.267 |
-0.726 |
0.321 |
| 1.4 |
0.9700 |
25.10 |
-0.202 |
0.267 |
-0.726 |
0.321 |
| 1.5 |
0.9680 |
31.60 |
-0.202 |
0.266 |
-0.723 |
0.318 |
| 1.6 |
0.9580 |
39.80 |
-0.202 |
0.266 |
-0.724 |
0.319 |
| 1.7 |
0.9410 |
50.10 |
-0.202 |
0.265 |
-0.723 |
0.318 |
| 1.8 |
0.9410 |
63.10 |
-0.202 |
0.265 |
-0.723 |
0.318 |
| 1.9 |
0.9400 |
79.40 |
-0.202 |
0.263 |
-0.719 |
0.314 |
| 2.0 |
0.9400 |
100.00 |
-0.202 |
0.263 |
-0.719 |
0.314 |
| 2.1 |
0.9380 |
126.00 |
-0.202 |
0.264 |
-0.720 |
0.315 |
| 2.2 |
0.8780 |
158.00 |
-0.202 |
0.276 |
-0.743 |
0.339 |
| 2.3 |
0.8760 |
200.00 |
-0.202 |
0.274 |
-0.740 |
0.336 |
| 2.4 |
0.8760 |
251.00 |
-0.202 |
0.274 |
-0.740 |
0.336 |
| 2.5 |
0.8710 |
316.00 |
-0.202 |
0.269 |
-0.729 |
0.324 |
| 2.6 |
0.8320 |
398.00 |
-0.202 |
0.275 |
-0.742 |
0.337 |
| 2.7 |
0.7830 |
501.00 |
-0.202 |
0.294 |
-0.779 |
0.375 |
| 2.8 |
0.7360 |
631.00 |
-0.202 |
0.305 |
-0.800 |
0.395 |
| 2.9 |
0.6600 |
794.00 |
-0.202 |
0.318 |
-0.826 |
0.421 |
| 3.0 |
0.6200 |
1000.00 |
-0.202 |
0.333 |
-0.855 |
0.450 |
| 3.1 |
0.5880 |
1260.00 |
-0.202 |
0.321 |
-0.832 |
0.427 |
| 3.2 |
0.5130 |
1580.00 |
-0.202 |
0.367 |
-0.922 |
0.517 |
| 3.3 |
0.4550 |
2000.00 |
-0.202 |
0.407 |
-0.999 |
0.595 |
| 3.4 |
0.3850 |
2510.00 |
-0.202 |
0.416 |
-1.020 |
0.614 |
| 3.5 |
0.3240 |
3160.00 |
-0.202 |
0.454 |
-1.090 |
0.687 |
| 3.6 |
0.2410 |
3980.00 |
-0.202 |
0.760 |
-1.690 |
1.290 |
| 3.7 |
0.1950 |
5010.00 |
-0.202 |
0.714 |
-1.600 |
1.200 |
| 3.8 |
0.1770 |
6310.00 |
-0.202 |
0.655 |
-1.490 |
1.080 |
| 3.9 |
0.1680 |
7940.00 |
-0.202 |
0.580 |
-1.340 |
0.934 |
| 4.0 |
0.1260 |
10000.00 |
-0.202 |
0.710 |
-1.590 |
1.190 |
| 4.1 |
0.1220 |
12600.00 |
-0.202 |
0.698 |
-1.570 |
1.170 |
| 4.2 |
0.1060 |
15800.00 |
-0.202 |
0.653 |
-1.480 |
1.080 |
| 4.3 |
0.0878 |
20000.00 |
-0.114 |
0.608 |
-1.310 |
1.080 |
IgG3 V1V2 B.CaseA-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.181 |
0.0122 |
0.15800 |
0.205 |
| 0.1 |
0.2810 |
1.26 |
0.181 |
0.0387 |
0.10600 |
0.257 |
| 0.2 |
0.2810 |
1.58 |
0.181 |
0.0387 |
0.10600 |
0.257 |
| 0.3 |
0.2810 |
2.00 |
0.181 |
0.0387 |
0.10600 |
0.257 |
| 0.4 |
0.2550 |
2.51 |
0.181 |
0.0394 |
0.10400 |
0.259 |
| 0.5 |
0.2530 |
3.16 |
0.181 |
0.0383 |
0.10600 |
0.257 |
| 0.6 |
0.2300 |
3.98 |
0.181 |
0.0503 |
0.08280 |
0.280 |
| 0.7 |
0.2080 |
5.01 |
0.181 |
0.0523 |
0.07890 |
0.284 |
| 0.8 |
0.1920 |
6.31 |
0.181 |
0.0688 |
0.04670 |
0.316 |
| 0.9 |
0.1920 |
7.94 |
0.181 |
0.0688 |
0.04670 |
0.316 |
| 1.0 |
0.1330 |
10.00 |
0.181 |
0.0977 |
-0.01000 |
0.373 |
| 1.1 |
0.1330 |
12.60 |
0.181 |
0.0977 |
-0.01000 |
0.373 |
| 1.2 |
0.1310 |
15.80 |
0.181 |
0.0967 |
-0.00817 |
0.371 |
| 1.3 |
0.1200 |
20.00 |
0.181 |
0.1080 |
-0.02990 |
0.393 |
| 1.4 |
0.1190 |
25.10 |
0.181 |
0.1050 |
-0.02400 |
0.387 |
| 1.5 |
0.1170 |
31.60 |
0.181 |
0.1080 |
-0.02990 |
0.393 |
| 1.6 |
0.1070 |
39.80 |
0.181 |
0.1020 |
-0.01850 |
0.381 |
| 1.7 |
0.0574 |
50.10 |
0.181 |
0.1240 |
-0.06070 |
0.424 |
| 1.8 |
0.0556 |
63.10 |
0.181 |
0.1270 |
-0.06770 |
0.431 |
| 1.9 |
0.0539 |
79.40 |
0.181 |
0.1360 |
-0.08580 |
0.449 |
| 2.0 |
0.0418 |
100.00 |
0.181 |
0.1420 |
-0.09670 |
0.460 |
| 2.1 |
0.0418 |
126.00 |
0.181 |
0.1420 |
-0.09670 |
0.460 |
| 2.2 |
0.0383 |
158.00 |
0.181 |
0.1580 |
-0.12900 |
0.492 |
| 2.3 |
0.0383 |
200.00 |
0.181 |
0.1580 |
-0.12900 |
0.492 |
| 2.4 |
0.0383 |
251.00 |
0.181 |
0.1580 |
-0.12900 |
0.492 |
| 2.5 |
0.0383 |
316.00 |
0.181 |
0.1580 |
-0.12900 |
0.492 |
| 2.6 |
0.0365 |
398.00 |
0.181 |
0.1130 |
-0.03990 |
0.403 |
| 2.7 |
0.0365 |
501.00 |
0.181 |
0.1130 |
-0.03990 |
0.403 |
| 2.8 |
0.0365 |
631.00 |
0.181 |
0.1130 |
-0.03990 |
0.403 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.0952 |
0.0122 |
0.0648 |
0.130 |
| 0.1 |
1.26 |
0.2810 |
0.1150 |
0.0387 |
0.0389 |
0.191 |
| 0.2 |
1.58 |
0.2810 |
0.1150 |
0.0387 |
0.0389 |
0.191 |
| 0.3 |
2.00 |
0.2810 |
0.1150 |
0.0387 |
0.0389 |
0.191 |
| 0.4 |
2.51 |
0.2550 |
0.1110 |
0.0394 |
0.0340 |
0.188 |
| 0.5 |
3.16 |
0.2530 |
0.1060 |
0.0383 |
0.0308 |
0.181 |
| 0.6 |
3.98 |
0.2300 |
0.1230 |
0.0503 |
0.0246 |
0.222 |
| 0.7 |
5.01 |
0.2080 |
0.1350 |
0.0523 |
0.0323 |
0.237 |
| 0.8 |
6.31 |
0.1920 |
0.1740 |
0.0688 |
0.0388 |
0.308 |
| 0.9 |
7.94 |
0.1920 |
0.1740 |
0.0688 |
0.0388 |
0.308 |
| 1.0 |
10.00 |
0.1330 |
0.2710 |
0.0977 |
0.0797 |
0.463 |
| 1.1 |
12.60 |
0.1330 |
0.2710 |
0.0977 |
0.0797 |
0.463 |
| 1.2 |
15.80 |
0.1310 |
0.2610 |
0.0967 |
0.0718 |
0.451 |
| 1.3 |
20.00 |
0.1200 |
0.2870 |
0.1080 |
0.0759 |
0.498 |
| 1.4 |
25.10 |
0.1190 |
0.2760 |
0.1050 |
0.0709 |
0.482 |
| 1.5 |
31.60 |
0.1170 |
0.2630 |
0.1080 |
0.0518 |
0.474 |
| 1.6 |
39.80 |
0.1070 |
0.4530 |
0.1020 |
0.2530 |
0.653 |
| 1.7 |
50.10 |
0.0574 |
0.5390 |
0.1240 |
0.2970 |
0.781 |
| 1.8 |
63.10 |
0.0556 |
0.5400 |
0.1270 |
0.2910 |
0.789 |
| 1.9 |
79.40 |
0.0539 |
0.5300 |
0.1360 |
0.2630 |
0.797 |
| 2.0 |
100.00 |
0.0418 |
0.5220 |
0.1420 |
0.2440 |
0.800 |
| 2.1 |
126.00 |
0.0418 |
0.5220 |
0.1420 |
0.2440 |
0.800 |
| 2.2 |
158.00 |
0.0383 |
0.5010 |
0.1580 |
0.1910 |
0.811 |
| 2.3 |
200.00 |
0.0383 |
0.5010 |
0.1580 |
0.1910 |
0.811 |
| 2.4 |
251.00 |
0.0383 |
0.5010 |
0.1580 |
0.1910 |
0.811 |
| 2.5 |
316.00 |
0.0383 |
0.5010 |
0.1580 |
0.1910 |
0.811 |
| 2.6 |
398.00 |
0.0365 |
0.3660 |
0.1130 |
0.1450 |
0.588 |
| 2.7 |
501.00 |
0.0365 |
0.3660 |
0.1130 |
0.1450 |
0.588 |
| 2.8 |
631.00 |
0.0365 |
0.3660 |
0.1130 |
0.1450 |
0.588 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
-1.2 |
0.344 |
-1.88 |
-0.5290 |
| 0.1 |
0.2810 |
1.26 |
-1.2 |
0.563 |
-2.31 |
-0.0998 |
| 0.2 |
0.2810 |
1.58 |
-1.2 |
0.563 |
-2.31 |
-0.0998 |
| 0.3 |
0.2810 |
2.00 |
-1.2 |
0.563 |
-2.31 |
-0.0998 |
| 0.4 |
0.2550 |
2.51 |
-1.2 |
0.571 |
-2.32 |
-0.0855 |
| 0.5 |
0.2530 |
3.16 |
-1.2 |
0.560 |
-2.30 |
-0.1070 |
| 0.6 |
0.2300 |
3.98 |
-1.2 |
0.686 |
-2.55 |
0.1400 |
| 0.7 |
0.2080 |
5.01 |
-1.2 |
0.707 |
-2.59 |
0.1830 |
| 0.8 |
0.1920 |
6.31 |
-1.2 |
0.891 |
-2.95 |
0.5430 |
| 0.9 |
0.1920 |
7.94 |
-1.2 |
0.891 |
-2.95 |
0.5430 |
| 1.0 |
0.1330 |
10.00 |
-1.2 |
1.230 |
-3.61 |
1.2000 |
| 1.1 |
0.1330 |
12.60 |
-1.2 |
1.230 |
-3.61 |
1.2000 |
| 1.2 |
0.1310 |
15.80 |
-1.2 |
1.220 |
-3.59 |
1.1800 |
| 1.3 |
0.1200 |
20.00 |
-1.2 |
1.350 |
-3.84 |
1.4300 |
| 1.4 |
0.1190 |
25.10 |
-1.2 |
1.310 |
-3.77 |
1.3600 |
| 1.5 |
0.1170 |
31.60 |
-1.2 |
1.350 |
-3.84 |
1.4300 |
| 1.6 |
0.1070 |
39.80 |
-1.2 |
1.280 |
-3.71 |
1.3000 |
| 1.7 |
0.0574 |
50.10 |
-1.2 |
1.530 |
-4.21 |
1.8000 |
| 1.8 |
0.0556 |
63.10 |
-1.2 |
1.580 |
-4.29 |
1.8800 |
| 1.9 |
0.0539 |
79.40 |
-1.2 |
1.690 |
-4.51 |
2.1000 |
| 2.0 |
0.0418 |
100.00 |
-1.2 |
1.750 |
-4.64 |
2.2300 |
| 2.1 |
0.0418 |
126.00 |
-1.2 |
1.750 |
-4.64 |
2.2300 |
| 2.2 |
0.0383 |
158.00 |
-1.2 |
1.950 |
-5.02 |
2.6200 |
| 2.3 |
0.0383 |
200.00 |
-1.2 |
1.950 |
-5.02 |
2.6200 |
| 2.4 |
0.0383 |
251.00 |
-1.2 |
1.950 |
-5.02 |
2.6200 |
| 2.5 |
0.0383 |
316.00 |
-1.2 |
1.950 |
-5.02 |
2.6200 |
| 2.6 |
0.0365 |
398.00 |
-1.2 |
1.410 |
-3.96 |
1.5500 |
| 2.7 |
0.0365 |
501.00 |
-1.2 |
1.410 |
-3.96 |
1.5500 |
| 2.8 |
0.0365 |
631.00 |
-1.2 |
1.410 |
-3.96 |
1.5500 |
IgG3 V1V2 C.1086-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.162 |
0.0122 |
0.1380 |
0.186 |
| 0.1 |
0.6850 |
1.26 |
0.162 |
0.0227 |
0.1180 |
0.207 |
| 0.2 |
0.6850 |
1.58 |
0.162 |
0.0227 |
0.1180 |
0.207 |
| 0.3 |
0.6830 |
2.00 |
0.162 |
0.0225 |
0.1180 |
0.206 |
| 0.4 |
0.6830 |
2.51 |
0.162 |
0.0225 |
0.1180 |
0.206 |
| 0.5 |
0.6580 |
3.16 |
0.162 |
0.0238 |
0.1160 |
0.209 |
| 0.6 |
0.6420 |
3.98 |
0.162 |
0.0248 |
0.1140 |
0.211 |
| 0.7 |
0.6420 |
5.01 |
0.162 |
0.0248 |
0.1140 |
0.211 |
| 0.8 |
0.6400 |
6.31 |
0.162 |
0.0245 |
0.1140 |
0.210 |
| 0.9 |
0.6400 |
7.94 |
0.162 |
0.0245 |
0.1140 |
0.210 |
| 1.0 |
0.6260 |
10.00 |
0.162 |
0.0263 |
0.1110 |
0.214 |
| 1.1 |
0.6030 |
12.60 |
0.162 |
0.0284 |
0.1070 |
0.218 |
| 1.2 |
0.6000 |
15.80 |
0.162 |
0.0278 |
0.1080 |
0.217 |
| 1.3 |
0.5850 |
20.00 |
0.162 |
0.0294 |
0.1050 |
0.220 |
| 1.4 |
0.5600 |
25.10 |
0.162 |
0.0302 |
0.1030 |
0.221 |
| 1.5 |
0.5360 |
31.60 |
0.162 |
0.0332 |
0.0972 |
0.227 |
| 1.6 |
0.4890 |
39.80 |
0.162 |
0.0403 |
0.0832 |
0.241 |
| 1.7 |
0.4860 |
50.10 |
0.162 |
0.0396 |
0.0846 |
0.240 |
| 1.8 |
0.4860 |
63.10 |
0.162 |
0.0396 |
0.0846 |
0.240 |
| 1.9 |
0.4610 |
79.40 |
0.162 |
0.0432 |
0.0776 |
0.247 |
| 2.0 |
0.4260 |
100.00 |
0.162 |
0.0397 |
0.0844 |
0.240 |
| 2.1 |
0.3420 |
126.00 |
0.162 |
0.0440 |
0.0760 |
0.248 |
| 2.2 |
0.3410 |
158.00 |
0.162 |
0.0435 |
0.0770 |
0.247 |
| 2.3 |
0.3370 |
200.00 |
0.162 |
0.0426 |
0.0787 |
0.246 |
| 2.4 |
0.2950 |
251.00 |
0.162 |
0.0528 |
0.0587 |
0.266 |
| 2.5 |
0.2940 |
316.00 |
0.162 |
0.0526 |
0.0592 |
0.265 |
| 2.6 |
0.2550 |
398.00 |
0.162 |
0.0545 |
0.0554 |
0.269 |
| 2.7 |
0.2270 |
501.00 |
0.162 |
0.0738 |
0.0175 |
0.307 |
| 2.8 |
0.1880 |
631.00 |
0.162 |
0.0960 |
-0.0259 |
0.350 |
| 2.9 |
0.1370 |
794.00 |
0.162 |
0.0945 |
-0.0229 |
0.347 |
| 3.0 |
0.0995 |
1000.00 |
0.162 |
0.1200 |
-0.0721 |
0.397 |
| 3.1 |
0.0977 |
1260.00 |
0.162 |
0.1270 |
-0.0862 |
0.411 |
| 3.2 |
0.0872 |
1580.00 |
0.162 |
0.1390 |
-0.1100 |
0.435 |
| 3.3 |
0.0629 |
2000.00 |
0.162 |
0.2420 |
-0.3110 |
0.636 |
| 3.4 |
0.0612 |
2510.00 |
0.162 |
0.2470 |
-0.3210 |
0.646 |
| 3.5 |
0.0369 |
3160.00 |
0.162 |
0.2540 |
-0.3350 |
0.660 |
| 3.6 |
0.0335 |
3980.00 |
0.162 |
0.2620 |
-0.3510 |
0.676 |
| 3.7 |
0.0317 |
5010.00 |
0.162 |
0.2700 |
-0.3670 |
0.692 |
| 3.8 |
0.0317 |
6310.00 |
0.162 |
0.2700 |
-0.3670 |
0.692 |
| 3.9 |
0.0156 |
7940.00 |
0.162 |
0.2810 |
-0.3890 |
0.713 |
| 4.0 |
0.0156 |
10000.00 |
0.162 |
0.2810 |
-0.3890 |
0.713 |
| 4.1 |
0.0156 |
12600.00 |
0.162 |
0.2810 |
-0.3890 |
0.713 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.0952 |
0.0122 |
0.0648 |
0.130 |
| 0.1 |
1.26 |
0.6850 |
0.1110 |
0.0227 |
0.0665 |
0.156 |
| 0.2 |
1.58 |
0.6850 |
0.1110 |
0.0227 |
0.0665 |
0.156 |
| 0.3 |
2.00 |
0.6830 |
0.1090 |
0.0225 |
0.0649 |
0.153 |
| 0.4 |
2.51 |
0.6830 |
0.1090 |
0.0225 |
0.0649 |
0.153 |
| 0.5 |
3.16 |
0.6580 |
0.1140 |
0.0238 |
0.0676 |
0.161 |
| 0.6 |
3.98 |
0.6420 |
0.1170 |
0.0248 |
0.0685 |
0.166 |
| 0.7 |
5.01 |
0.6420 |
0.1170 |
0.0248 |
0.0685 |
0.166 |
| 0.8 |
6.31 |
0.6400 |
0.1150 |
0.0245 |
0.0669 |
0.163 |
| 0.9 |
7.94 |
0.6400 |
0.1150 |
0.0245 |
0.0669 |
0.163 |
| 1.0 |
10.00 |
0.6260 |
0.1220 |
0.0263 |
0.0708 |
0.174 |
| 1.1 |
12.60 |
0.6030 |
0.1280 |
0.0284 |
0.0727 |
0.184 |
| 1.2 |
15.80 |
0.6000 |
0.1240 |
0.0278 |
0.0692 |
0.178 |
| 1.3 |
20.00 |
0.5850 |
0.1300 |
0.0294 |
0.0724 |
0.187 |
| 1.4 |
25.10 |
0.5600 |
0.1310 |
0.0302 |
0.0724 |
0.191 |
| 1.5 |
31.60 |
0.5360 |
0.1380 |
0.0332 |
0.0725 |
0.203 |
| 1.6 |
39.80 |
0.4890 |
0.1640 |
0.0403 |
0.0846 |
0.243 |
| 1.7 |
50.10 |
0.4860 |
0.1580 |
0.0396 |
0.0800 |
0.235 |
| 1.8 |
63.10 |
0.4860 |
0.1580 |
0.0396 |
0.0800 |
0.235 |
| 1.9 |
79.40 |
0.4610 |
0.1670 |
0.0432 |
0.0828 |
0.252 |
| 2.0 |
100.00 |
0.4260 |
0.1600 |
0.0397 |
0.0825 |
0.238 |
| 2.1 |
126.00 |
0.3420 |
0.1760 |
0.0440 |
0.0894 |
0.262 |
| 2.2 |
158.00 |
0.3410 |
0.1690 |
0.0435 |
0.0841 |
0.255 |
| 2.3 |
200.00 |
0.3370 |
0.1640 |
0.0426 |
0.0802 |
0.247 |
| 2.4 |
251.00 |
0.2950 |
0.2300 |
0.0528 |
0.1260 |
0.333 |
| 2.5 |
316.00 |
0.2940 |
0.2260 |
0.0526 |
0.1230 |
0.329 |
| 2.6 |
398.00 |
0.2550 |
0.2230 |
0.0545 |
0.1160 |
0.330 |
| 2.7 |
501.00 |
0.2270 |
0.3110 |
0.0738 |
0.1660 |
0.456 |
| 2.8 |
631.00 |
0.1880 |
0.3280 |
0.0960 |
0.1400 |
0.516 |
| 2.9 |
794.00 |
0.1370 |
0.3000 |
0.0945 |
0.1150 |
0.486 |
| 3.0 |
1000.00 |
0.0995 |
0.3730 |
0.1200 |
0.1390 |
0.608 |
| 3.1 |
1260.00 |
0.0977 |
0.3760 |
0.1270 |
0.1280 |
0.625 |
| 3.2 |
1580.00 |
0.0872 |
0.4340 |
0.1390 |
0.1620 |
0.707 |
| 3.3 |
2000.00 |
0.0629 |
0.6380 |
0.2420 |
0.1650 |
1.110 |
| 3.4 |
2510.00 |
0.0612 |
0.6300 |
0.2470 |
0.1470 |
1.110 |
| 3.5 |
3160.00 |
0.0369 |
0.7250 |
0.2540 |
0.2280 |
1.220 |
| 3.6 |
3980.00 |
0.0335 |
0.7030 |
0.2620 |
0.1900 |
1.220 |
| 3.7 |
5010.00 |
0.0317 |
0.6880 |
0.2700 |
0.1580 |
1.220 |
| 3.8 |
6310.00 |
0.0317 |
0.6880 |
0.2700 |
0.1580 |
1.220 |
| 3.9 |
7940.00 |
0.0156 |
0.5760 |
0.2810 |
0.0248 |
1.130 |
| 4.0 |
10000.00 |
0.0156 |
0.5760 |
0.2810 |
0.0248 |
1.130 |
| 4.1 |
12600.00 |
0.0156 |
0.5760 |
0.2810 |
0.0248 |
1.130 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
-0.971 |
0.315 |
-1.59 |
-0.3540 |
| 0.1 |
0.6850 |
1.26 |
-0.971 |
0.392 |
-1.74 |
-0.2030 |
| 0.2 |
0.6850 |
1.58 |
-0.971 |
0.392 |
-1.74 |
-0.2030 |
| 0.3 |
0.6830 |
2.00 |
-0.971 |
0.390 |
-1.73 |
-0.2060 |
| 0.4 |
0.6830 |
2.51 |
-0.971 |
0.390 |
-1.73 |
-0.2060 |
| 0.5 |
0.6580 |
3.16 |
-0.971 |
0.401 |
-1.76 |
-0.1850 |
| 0.6 |
0.6420 |
3.98 |
-0.971 |
0.410 |
-1.77 |
-0.1680 |
| 0.7 |
0.6420 |
5.01 |
-0.971 |
0.410 |
-1.77 |
-0.1680 |
| 0.8 |
0.6400 |
6.31 |
-0.971 |
0.407 |
-1.77 |
-0.1720 |
| 0.9 |
0.6400 |
7.94 |
-0.971 |
0.407 |
-1.77 |
-0.1720 |
| 1.0 |
0.6260 |
10.00 |
-0.971 |
0.423 |
-1.80 |
-0.1420 |
| 1.1 |
0.6030 |
12.60 |
-0.971 |
0.443 |
-1.84 |
-0.1020 |
| 1.2 |
0.6000 |
15.80 |
-0.971 |
0.437 |
-1.83 |
-0.1140 |
| 1.3 |
0.5850 |
20.00 |
-0.971 |
0.452 |
-1.86 |
-0.0845 |
| 1.4 |
0.5600 |
25.10 |
-0.971 |
0.460 |
-1.87 |
-0.0697 |
| 1.5 |
0.5360 |
31.60 |
-0.971 |
0.490 |
-1.93 |
-0.0109 |
| 1.6 |
0.4890 |
39.80 |
-0.971 |
0.563 |
-2.07 |
0.1330 |
| 1.7 |
0.4860 |
50.10 |
-0.971 |
0.556 |
-2.06 |
0.1180 |
| 1.8 |
0.4860 |
63.10 |
-0.971 |
0.556 |
-2.06 |
0.1180 |
| 1.9 |
0.4610 |
79.40 |
-0.971 |
0.593 |
-2.13 |
0.1920 |
| 2.0 |
0.4260 |
100.00 |
-0.971 |
0.556 |
-2.06 |
0.1200 |
| 2.1 |
0.3420 |
126.00 |
-0.971 |
0.602 |
-2.15 |
0.2100 |
| 2.2 |
0.3410 |
158.00 |
-0.971 |
0.597 |
-2.14 |
0.1990 |
| 2.3 |
0.3370 |
200.00 |
-0.971 |
0.588 |
-2.12 |
0.1810 |
| 2.4 |
0.2950 |
251.00 |
-0.971 |
0.699 |
-2.34 |
0.4000 |
| 2.5 |
0.2940 |
316.00 |
-0.971 |
0.696 |
-2.34 |
0.3940 |
| 2.6 |
0.2550 |
398.00 |
-0.971 |
0.718 |
-2.38 |
0.4370 |
| 2.7 |
0.2270 |
501.00 |
-0.971 |
0.939 |
-2.81 |
0.8700 |
| 2.8 |
0.1880 |
631.00 |
-0.971 |
1.200 |
-3.32 |
1.3800 |
| 2.9 |
0.1370 |
794.00 |
-0.971 |
1.180 |
-3.29 |
1.3400 |
| 3.0 |
0.0995 |
1000.00 |
-0.971 |
1.480 |
-3.87 |
1.9300 |
| 3.1 |
0.0977 |
1260.00 |
-0.971 |
1.560 |
-4.04 |
2.1000 |
| 3.2 |
0.0872 |
1580.00 |
-0.971 |
1.710 |
-4.33 |
2.3900 |
| 3.3 |
0.0629 |
2000.00 |
-0.971 |
2.950 |
-6.75 |
4.8100 |
| 3.4 |
0.0612 |
2510.00 |
-0.971 |
3.010 |
-6.87 |
4.9300 |
| 3.5 |
0.0369 |
3160.00 |
-0.971 |
3.100 |
-7.04 |
5.1000 |
| 3.6 |
0.0335 |
3980.00 |
-0.971 |
3.190 |
-7.23 |
5.2900 |
| 3.7 |
0.0317 |
5010.00 |
-0.971 |
3.290 |
-7.43 |
5.4900 |
| 3.8 |
0.0317 |
6310.00 |
-0.971 |
3.290 |
-7.43 |
5.4900 |
| 3.9 |
0.0156 |
7940.00 |
-0.971 |
3.430 |
-7.68 |
5.7400 |
| 4.0 |
0.0156 |
10000.00 |
-0.971 |
3.430 |
-7.68 |
5.7400 |
| 4.1 |
0.0156 |
12600.00 |
-0.971 |
3.430 |
-7.68 |
5.7400 |
HVTN 505
- Adjustment covariates: age, racecc, BMI,
bhvrisk
- Event time variable: HIVwk28preunblfu
- Event type variable: HIVwk28preunbl
- Weight variable: weight
- Reference timepoint: 514 days
- All learners: GLM
IgG V1V2 B.CaseA-gp70
Monotone

| 0.0 |
1.000 |
1.00 |
0.0913 |
0.0174 |
0.057100 |
0.125 |
| 0.1 |
0.282 |
1.26 |
0.0570 |
0.0238 |
0.010400 |
0.104 |
| 0.2 |
0.282 |
1.58 |
0.0570 |
0.0238 |
0.010400 |
0.104 |
| 0.3 |
0.282 |
2.00 |
0.0570 |
0.0238 |
0.010400 |
0.104 |
| 0.4 |
0.273 |
2.51 |
0.0570 |
0.0248 |
0.008420 |
0.106 |
| 0.5 |
0.273 |
3.16 |
0.0570 |
0.0248 |
0.008420 |
0.106 |
| 0.6 |
0.273 |
3.98 |
0.0570 |
0.0248 |
0.008420 |
0.106 |
| 0.7 |
0.253 |
5.01 |
0.0570 |
0.0258 |
0.006380 |
0.108 |
| 0.8 |
0.253 |
6.31 |
0.0570 |
0.0258 |
0.006380 |
0.108 |
| 0.9 |
0.253 |
7.94 |
0.0570 |
0.0258 |
0.006380 |
0.108 |
| 1.0 |
0.248 |
10.00 |
0.0570 |
0.0271 |
0.003900 |
0.110 |
| 1.1 |
0.236 |
12.60 |
0.0570 |
0.0286 |
0.000932 |
0.113 |
| 1.2 |
0.236 |
15.80 |
0.0570 |
0.0286 |
0.000932 |
0.113 |
| 1.3 |
0.236 |
20.00 |
0.0570 |
0.0286 |
0.000932 |
0.113 |
| 1.4 |
0.211 |
25.10 |
0.0570 |
0.0317 |
-0.005170 |
0.119 |
| 1.5 |
0.207 |
31.60 |
0.0570 |
0.0332 |
-0.008050 |
0.122 |
| 1.6 |
0.207 |
39.80 |
0.0570 |
0.0332 |
-0.008050 |
0.122 |
| 1.7 |
0.207 |
50.10 |
0.0570 |
0.0332 |
-0.008050 |
0.122 |
| 1.8 |
0.196 |
63.10 |
0.0570 |
0.0349 |
-0.011500 |
0.125 |
| 1.9 |
0.182 |
79.40 |
0.0570 |
0.0387 |
-0.018900 |
0.133 |
| 2.0 |
0.173 |
100.00 |
0.0570 |
0.0391 |
-0.019600 |
0.134 |
| 2.1 |
0.141 |
126.00 |
0.0570 |
0.0455 |
-0.032100 |
0.146 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.0913 |
0.0174 |
0.049500 |
0.1220 |
| 0.1 |
1.26 |
0.282 |
0.0464 |
0.0238 |
-0.000179 |
0.0930 |
| 0.2 |
1.58 |
0.282 |
0.0464 |
0.0238 |
-0.000179 |
0.0930 |
| 0.3 |
2.00 |
0.282 |
0.0464 |
0.0238 |
-0.000179 |
0.0930 |
| 0.4 |
2.51 |
0.273 |
0.0476 |
0.0248 |
-0.000919 |
0.0962 |
| 0.5 |
3.16 |
0.273 |
0.0476 |
0.0248 |
-0.000919 |
0.0962 |
| 0.6 |
3.98 |
0.273 |
0.0476 |
0.0248 |
-0.000919 |
0.0962 |
| 0.7 |
5.01 |
0.253 |
0.0493 |
0.0258 |
-0.001260 |
0.0999 |
| 0.8 |
6.31 |
0.253 |
0.0493 |
0.0258 |
-0.001260 |
0.0999 |
| 0.9 |
7.94 |
0.253 |
0.0493 |
0.0258 |
-0.001260 |
0.0999 |
| 1.0 |
10.00 |
0.248 |
0.0541 |
0.0271 |
0.001060 |
0.1070 |
| 1.1 |
12.60 |
0.236 |
0.0557 |
0.0286 |
-0.000311 |
0.1120 |
| 1.2 |
15.80 |
0.236 |
0.0557 |
0.0286 |
-0.000311 |
0.1120 |
| 1.3 |
20.00 |
0.236 |
0.0557 |
0.0286 |
-0.000311 |
0.1120 |
| 1.4 |
25.10 |
0.211 |
0.0619 |
0.0317 |
-0.000237 |
0.1240 |
| 1.5 |
31.60 |
0.207 |
0.0662 |
0.0332 |
0.001180 |
0.1310 |
| 1.6 |
39.80 |
0.207 |
0.0662 |
0.0332 |
0.001180 |
0.1310 |
| 1.7 |
50.10 |
0.207 |
0.0662 |
0.0332 |
0.001180 |
0.1310 |
| 1.8 |
63.10 |
0.196 |
0.0696 |
0.0349 |
0.001200 |
0.1380 |
| 1.9 |
79.40 |
0.182 |
0.0689 |
0.0387 |
-0.006920 |
0.1450 |
| 2.0 |
100.00 |
0.173 |
0.0700 |
0.0391 |
-0.006530 |
0.1470 |
| 2.1 |
126.00 |
0.141 |
0.0758 |
0.0455 |
-0.013300 |
0.1650 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
-0.319 |
0.387 |
-1.080 |
0.439 |
| 0.1 |
0.282 |
1.26 |
0.177 |
0.389 |
-0.586 |
0.940 |
| 0.2 |
0.282 |
1.58 |
0.177 |
0.389 |
-0.586 |
0.940 |
| 0.3 |
0.282 |
2.00 |
0.177 |
0.389 |
-0.586 |
0.940 |
| 0.4 |
0.273 |
2.51 |
0.177 |
0.402 |
-0.611 |
0.965 |
| 0.5 |
0.273 |
3.16 |
0.177 |
0.402 |
-0.611 |
0.965 |
| 0.6 |
0.273 |
3.98 |
0.177 |
0.402 |
-0.611 |
0.965 |
| 0.7 |
0.253 |
5.01 |
0.177 |
0.415 |
-0.637 |
0.991 |
| 0.8 |
0.253 |
6.31 |
0.177 |
0.415 |
-0.637 |
0.991 |
| 0.9 |
0.253 |
7.94 |
0.177 |
0.415 |
-0.637 |
0.991 |
| 1.0 |
0.248 |
10.00 |
0.177 |
0.432 |
-0.670 |
1.020 |
| 1.1 |
0.236 |
12.60 |
0.177 |
0.452 |
-0.709 |
1.060 |
| 1.2 |
0.236 |
15.80 |
0.177 |
0.452 |
-0.709 |
1.060 |
| 1.3 |
0.236 |
20.00 |
0.177 |
0.452 |
-0.709 |
1.060 |
| 1.4 |
0.211 |
25.10 |
0.177 |
0.493 |
-0.790 |
1.140 |
| 1.5 |
0.207 |
31.60 |
0.177 |
0.513 |
-0.829 |
1.180 |
| 1.6 |
0.207 |
39.80 |
0.177 |
0.513 |
-0.829 |
1.180 |
| 1.7 |
0.207 |
50.10 |
0.177 |
0.513 |
-0.829 |
1.180 |
| 1.8 |
0.196 |
63.10 |
0.177 |
0.537 |
-0.875 |
1.230 |
| 1.9 |
0.182 |
79.40 |
0.177 |
0.588 |
-0.976 |
1.330 |
| 2.0 |
0.173 |
100.00 |
0.177 |
0.593 |
-0.986 |
1.340 |
| 2.1 |
0.141 |
126.00 |
0.177 |
0.682 |
-1.160 |
1.510 |
IgG V1V2 C.1086-gp70
Monotone

| 0.0 |
1.000 |
1.00 |
0.0913 |
0.0174 |
0.057100 |
0.1250 |
| 0.1 |
0.411 |
1.26 |
0.0530 |
0.0232 |
0.007610 |
0.0985 |
| 0.2 |
0.411 |
1.58 |
0.0530 |
0.0232 |
0.007610 |
0.0985 |
| 0.3 |
0.411 |
2.00 |
0.0530 |
0.0232 |
0.007610 |
0.0985 |
| 0.4 |
0.399 |
2.51 |
0.0530 |
0.0235 |
0.007000 |
0.0991 |
| 0.5 |
0.387 |
3.16 |
0.0530 |
0.0240 |
0.005930 |
0.1000 |
| 0.6 |
0.387 |
3.98 |
0.0530 |
0.0240 |
0.005930 |
0.1000 |
| 0.7 |
0.379 |
5.01 |
0.0530 |
0.0238 |
0.006340 |
0.0998 |
| 0.8 |
0.374 |
6.31 |
0.0530 |
0.0245 |
0.005000 |
0.1010 |
| 0.9 |
0.374 |
7.94 |
0.0530 |
0.0245 |
0.005000 |
0.1010 |
| 1.0 |
0.353 |
10.00 |
0.0530 |
0.0248 |
0.004360 |
0.1020 |
| 1.1 |
0.345 |
12.60 |
0.0530 |
0.0250 |
0.004010 |
0.1020 |
| 1.2 |
0.336 |
15.80 |
0.0530 |
0.0252 |
0.003740 |
0.1020 |
| 1.3 |
0.328 |
20.00 |
0.0530 |
0.0257 |
0.002770 |
0.1030 |
| 1.4 |
0.320 |
25.10 |
0.0510 |
0.0225 |
0.006780 |
0.0952 |
| 1.5 |
0.296 |
31.60 |
0.0510 |
0.0234 |
0.005180 |
0.0968 |
| 1.6 |
0.291 |
39.80 |
0.0510 |
0.0248 |
0.002460 |
0.0995 |
| 1.7 |
0.291 |
50.10 |
0.0510 |
0.0248 |
0.002460 |
0.0995 |
| 1.8 |
0.280 |
63.10 |
0.0510 |
0.0257 |
0.000605 |
0.1010 |
| 1.9 |
0.275 |
79.40 |
0.0510 |
0.0265 |
-0.000994 |
0.1030 |
| 2.0 |
0.258 |
100.00 |
0.0510 |
0.0277 |
-0.003390 |
0.1050 |
| 2.1 |
0.252 |
126.00 |
0.0510 |
0.0296 |
-0.007020 |
0.1090 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.0913 |
0.0174 |
0.049500 |
0.1220 |
| 0.1 |
1.26 |
0.411 |
0.0510 |
0.0232 |
0.005520 |
0.0964 |
| 0.2 |
1.58 |
0.411 |
0.0510 |
0.0232 |
0.005520 |
0.0964 |
| 0.3 |
2.00 |
0.411 |
0.0510 |
0.0232 |
0.005520 |
0.0964 |
| 0.4 |
2.51 |
0.399 |
0.0516 |
0.0235 |
0.005510 |
0.0976 |
| 0.5 |
3.16 |
0.387 |
0.0524 |
0.0240 |
0.005280 |
0.0995 |
| 0.6 |
3.98 |
0.387 |
0.0524 |
0.0240 |
0.005280 |
0.0995 |
| 0.7 |
5.01 |
0.379 |
0.0522 |
0.0238 |
0.005480 |
0.0989 |
| 0.8 |
6.31 |
0.374 |
0.0540 |
0.0245 |
0.005970 |
0.1020 |
| 0.9 |
7.94 |
0.374 |
0.0540 |
0.0245 |
0.005970 |
0.1020 |
| 1.0 |
10.00 |
0.353 |
0.0546 |
0.0248 |
0.005910 |
0.1030 |
| 1.1 |
12.60 |
0.345 |
0.0549 |
0.0250 |
0.005860 |
0.1040 |
| 1.2 |
15.80 |
0.336 |
0.0550 |
0.0252 |
0.005730 |
0.1040 |
| 1.3 |
20.00 |
0.328 |
0.0557 |
0.0257 |
0.005370 |
0.1060 |
| 1.4 |
25.10 |
0.320 |
0.0438 |
0.0225 |
-0.000362 |
0.0880 |
| 1.5 |
31.60 |
0.296 |
0.0452 |
0.0234 |
-0.000624 |
0.0910 |
| 1.6 |
39.80 |
0.291 |
0.0500 |
0.0248 |
0.001540 |
0.0986 |
| 1.7 |
50.10 |
0.291 |
0.0500 |
0.0248 |
0.001540 |
0.0986 |
| 1.8 |
63.10 |
0.280 |
0.0517 |
0.0257 |
0.001360 |
0.1020 |
| 1.9 |
79.40 |
0.275 |
0.0531 |
0.0265 |
0.001150 |
0.1050 |
| 2.0 |
100.00 |
0.258 |
0.0550 |
0.0277 |
0.000610 |
0.1090 |
| 2.1 |
126.00 |
0.252 |
0.0589 |
0.0296 |
0.000881 |
0.1170 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
-0.319 |
0.387 |
-1.080 |
0.439 |
| 0.1 |
0.411 |
1.26 |
0.234 |
0.376 |
-0.503 |
0.970 |
| 0.2 |
0.411 |
1.58 |
0.234 |
0.376 |
-0.503 |
0.970 |
| 0.3 |
0.411 |
2.00 |
0.234 |
0.376 |
-0.503 |
0.970 |
| 0.4 |
0.399 |
2.51 |
0.234 |
0.380 |
-0.511 |
0.978 |
| 0.5 |
0.387 |
3.16 |
0.234 |
0.387 |
-0.525 |
0.992 |
| 0.6 |
0.387 |
3.98 |
0.234 |
0.387 |
-0.525 |
0.992 |
| 0.7 |
0.379 |
5.01 |
0.234 |
0.384 |
-0.520 |
0.987 |
| 0.8 |
0.374 |
6.31 |
0.234 |
0.393 |
-0.537 |
1.000 |
| 0.9 |
0.374 |
7.94 |
0.234 |
0.393 |
-0.537 |
1.000 |
| 1.0 |
0.353 |
10.00 |
0.234 |
0.397 |
-0.545 |
1.010 |
| 1.1 |
0.345 |
12.60 |
0.234 |
0.400 |
-0.550 |
1.020 |
| 1.2 |
0.336 |
15.80 |
0.234 |
0.402 |
-0.553 |
1.020 |
| 1.3 |
0.328 |
20.00 |
0.234 |
0.408 |
-0.566 |
1.030 |
| 1.4 |
0.320 |
25.10 |
0.263 |
0.365 |
-0.451 |
0.978 |
| 1.5 |
0.296 |
31.60 |
0.263 |
0.375 |
-0.472 |
0.999 |
| 1.6 |
0.291 |
39.80 |
0.263 |
0.393 |
-0.507 |
1.030 |
| 1.7 |
0.291 |
50.10 |
0.263 |
0.393 |
-0.507 |
1.030 |
| 1.8 |
0.280 |
63.10 |
0.263 |
0.406 |
-0.532 |
1.060 |
| 1.9 |
0.275 |
79.40 |
0.263 |
0.417 |
-0.553 |
1.080 |
| 2.0 |
0.258 |
100.00 |
0.263 |
0.433 |
-0.585 |
1.110 |
| 2.1 |
0.252 |
126.00 |
0.263 |
0.458 |
-0.634 |
1.160 |
IgG3 V1V2 B.CaseA-gp70
Monotone

| 0.0 |
1.000 |
1.00 |
0.0913 |
0.0174 |
0.05710 |
0.125 |
| 0.1 |
0.546 |
1.26 |
0.0811 |
0.0238 |
0.03450 |
0.128 |
| 0.2 |
0.514 |
1.58 |
0.0793 |
0.0223 |
0.03560 |
0.123 |
| 0.3 |
0.514 |
2.00 |
0.0793 |
0.0223 |
0.03560 |
0.123 |
| 0.4 |
0.446 |
2.51 |
0.0793 |
0.0253 |
0.02970 |
0.129 |
| 0.5 |
0.414 |
3.16 |
0.0793 |
0.0266 |
0.02710 |
0.132 |
| 0.6 |
0.375 |
3.98 |
0.0793 |
0.0298 |
0.02090 |
0.138 |
| 0.7 |
0.319 |
5.01 |
0.0793 |
0.0361 |
0.00854 |
0.150 |
| 0.8 |
0.306 |
6.31 |
0.0793 |
0.0385 |
0.00378 |
0.155 |
| 0.9 |
0.279 |
7.94 |
0.0793 |
0.0427 |
-0.00446 |
0.163 |
| 1.0 |
0.232 |
10.00 |
0.0793 |
0.0449 |
-0.00868 |
0.167 |
| 1.1 |
0.190 |
12.60 |
0.0793 |
0.0500 |
-0.01860 |
0.177 |
| 1.2 |
0.178 |
15.80 |
0.0793 |
0.0485 |
-0.01580 |
0.174 |
| 1.3 |
0.164 |
20.00 |
0.0793 |
0.0521 |
-0.02280 |
0.181 |
| 1.4 |
0.164 |
25.10 |
0.0793 |
0.0521 |
-0.02280 |
0.181 |
| 1.5 |
0.144 |
31.60 |
0.0793 |
0.0473 |
-0.01340 |
0.172 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.0913 |
0.0174 |
0.057400 |
0.133 |
| 0.1 |
1.26 |
0.546 |
0.0811 |
0.0238 |
0.034500 |
0.128 |
| 0.2 |
1.58 |
0.514 |
0.0732 |
0.0223 |
0.029400 |
0.117 |
| 0.3 |
2.00 |
0.514 |
0.0732 |
0.0223 |
0.029400 |
0.117 |
| 0.4 |
2.51 |
0.446 |
0.0783 |
0.0253 |
0.028600 |
0.128 |
| 0.5 |
3.16 |
0.414 |
0.0827 |
0.0266 |
0.030500 |
0.135 |
| 0.6 |
3.98 |
0.375 |
0.0907 |
0.0298 |
0.032200 |
0.149 |
| 0.7 |
5.01 |
0.319 |
0.1050 |
0.0361 |
0.034200 |
0.176 |
| 0.8 |
6.31 |
0.306 |
0.1120 |
0.0385 |
0.036000 |
0.187 |
| 0.9 |
7.94 |
0.279 |
0.1200 |
0.0427 |
0.036400 |
0.204 |
| 1.0 |
10.00 |
0.232 |
0.0954 |
0.0449 |
0.007410 |
0.183 |
| 1.1 |
12.60 |
0.190 |
0.1090 |
0.0500 |
0.011500 |
0.207 |
| 1.2 |
15.80 |
0.178 |
0.1090 |
0.0485 |
0.014000 |
0.204 |
| 1.3 |
20.00 |
0.164 |
0.1100 |
0.0521 |
0.007590 |
0.212 |
| 1.4 |
25.10 |
0.164 |
0.1100 |
0.0521 |
0.007590 |
0.212 |
| 1.5 |
31.60 |
0.144 |
0.0921 |
0.0473 |
-0.000628 |
0.185 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
-0.319 |
0.387 |
-1.080 |
0.439 |
| 0.1 |
0.546 |
1.26 |
-0.172 |
0.432 |
-1.020 |
0.674 |
| 0.2 |
0.514 |
1.58 |
-0.146 |
0.411 |
-0.952 |
0.660 |
| 0.3 |
0.514 |
2.00 |
-0.146 |
0.411 |
-0.952 |
0.660 |
| 0.4 |
0.446 |
2.51 |
-0.146 |
0.446 |
-1.020 |
0.728 |
| 0.5 |
0.414 |
3.16 |
-0.146 |
0.462 |
-1.050 |
0.759 |
| 0.6 |
0.375 |
3.98 |
-0.146 |
0.501 |
-1.130 |
0.835 |
| 0.7 |
0.319 |
5.01 |
-0.146 |
0.581 |
-1.280 |
0.992 |
| 0.8 |
0.306 |
6.31 |
-0.146 |
0.612 |
-1.350 |
1.050 |
| 0.9 |
0.279 |
7.94 |
-0.146 |
0.668 |
-1.460 |
1.160 |
| 1.0 |
0.232 |
10.00 |
-0.146 |
0.697 |
-1.510 |
1.220 |
| 1.1 |
0.190 |
12.60 |
-0.146 |
0.765 |
-1.650 |
1.350 |
| 1.2 |
0.178 |
15.80 |
-0.146 |
0.746 |
-1.610 |
1.320 |
| 1.3 |
0.164 |
20.00 |
-0.146 |
0.795 |
-1.700 |
1.410 |
| 1.4 |
0.164 |
25.10 |
-0.146 |
0.795 |
-1.700 |
1.410 |
| 1.5 |
0.144 |
31.60 |
-0.146 |
0.730 |
-1.580 |
1.280 |
IgG3 V1V2 C.1086-gp70
Monotone

| 0.0 |
1.000 |
1.00 |
0.0913 |
0.0174 |
0.05710 |
0.125 |
| 0.1 |
0.740 |
1.26 |
0.0848 |
0.0213 |
0.04310 |
0.127 |
| 0.2 |
0.732 |
1.58 |
0.0848 |
0.0216 |
0.04250 |
0.127 |
| 0.3 |
0.722 |
2.00 |
0.0829 |
0.0215 |
0.04090 |
0.125 |
| 0.4 |
0.666 |
2.51 |
0.0829 |
0.0224 |
0.03900 |
0.127 |
| 0.5 |
0.666 |
3.16 |
0.0829 |
0.0224 |
0.03900 |
0.127 |
| 0.6 |
0.628 |
3.98 |
0.0829 |
0.0231 |
0.03770 |
0.128 |
| 0.7 |
0.571 |
5.01 |
0.0712 |
0.0213 |
0.02940 |
0.113 |
| 0.8 |
0.528 |
6.31 |
0.0712 |
0.0225 |
0.02710 |
0.115 |
| 0.9 |
0.472 |
7.94 |
0.0712 |
0.0251 |
0.02200 |
0.120 |
| 1.0 |
0.387 |
10.00 |
0.0712 |
0.0276 |
0.01710 |
0.125 |
| 1.1 |
0.347 |
12.60 |
0.0712 |
0.0285 |
0.01530 |
0.127 |
| 1.2 |
0.319 |
15.80 |
0.0712 |
0.0320 |
0.00858 |
0.134 |
| 1.3 |
0.259 |
20.00 |
0.0712 |
0.0352 |
0.00223 |
0.140 |
| 1.4 |
0.241 |
25.10 |
0.0712 |
0.0389 |
-0.00494 |
0.147 |
| 1.5 |
0.195 |
31.60 |
0.0712 |
0.0605 |
-0.04730 |
0.190 |
| 1.6 |
0.156 |
39.80 |
0.0712 |
0.0402 |
-0.00761 |
0.150 |
| 1.7 |
0.147 |
50.10 |
0.0712 |
0.0406 |
-0.00833 |
0.151 |
| 1.8 |
0.132 |
63.10 |
0.0712 |
0.0493 |
-0.02540 |
0.168 |
| 1.9 |
0.128 |
79.40 |
0.0712 |
0.0469 |
-0.02060 |
0.163 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.0913 |
0.0174 |
0.05740 |
0.133 |
| 0.1 |
1.26 |
0.740 |
0.0844 |
0.0213 |
0.04260 |
0.126 |
| 0.2 |
1.58 |
0.732 |
0.0853 |
0.0216 |
0.04300 |
0.128 |
| 0.3 |
2.00 |
0.722 |
0.0821 |
0.0215 |
0.04000 |
0.124 |
| 0.4 |
2.51 |
0.666 |
0.0822 |
0.0224 |
0.03820 |
0.126 |
| 0.5 |
3.16 |
0.666 |
0.0822 |
0.0224 |
0.03820 |
0.126 |
| 0.6 |
3.98 |
0.628 |
0.0853 |
0.0231 |
0.04000 |
0.131 |
| 0.7 |
5.01 |
0.571 |
0.0662 |
0.0213 |
0.02440 |
0.108 |
| 0.8 |
6.31 |
0.528 |
0.0703 |
0.0225 |
0.02610 |
0.114 |
| 0.9 |
7.94 |
0.472 |
0.0774 |
0.0251 |
0.02820 |
0.127 |
| 1.0 |
10.00 |
0.387 |
0.0831 |
0.0276 |
0.02890 |
0.137 |
| 1.1 |
12.60 |
0.347 |
0.0801 |
0.0285 |
0.02410 |
0.136 |
| 1.2 |
15.80 |
0.319 |
0.0896 |
0.0320 |
0.02690 |
0.152 |
| 1.3 |
20.00 |
0.259 |
0.0916 |
0.0352 |
0.02260 |
0.161 |
| 1.4 |
25.10 |
0.241 |
0.1040 |
0.0389 |
0.02740 |
0.180 |
| 1.5 |
31.60 |
0.195 |
0.1450 |
0.0605 |
0.02600 |
0.263 |
| 1.6 |
39.80 |
0.156 |
0.0897 |
0.0402 |
0.01090 |
0.169 |
| 1.7 |
50.10 |
0.147 |
0.0851 |
0.0406 |
0.00557 |
0.165 |
| 1.8 |
63.10 |
0.132 |
0.1010 |
0.0493 |
0.00406 |
0.197 |
| 1.9 |
79.40 |
0.128 |
0.0871 |
0.0469 |
-0.00473 |
0.179 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
-0.3190 |
0.387 |
-1.080 |
0.439 |
| 0.1 |
0.740 |
1.26 |
-0.2260 |
0.411 |
-1.030 |
0.580 |
| 0.2 |
0.732 |
1.58 |
-0.2260 |
0.414 |
-1.040 |
0.586 |
| 0.3 |
0.722 |
2.00 |
-0.1990 |
0.409 |
-1.000 |
0.603 |
| 0.4 |
0.666 |
2.51 |
-0.1990 |
0.420 |
-1.020 |
0.624 |
| 0.5 |
0.666 |
3.16 |
-0.1990 |
0.420 |
-1.020 |
0.624 |
| 0.6 |
0.628 |
3.98 |
-0.1990 |
0.427 |
-1.040 |
0.639 |
| 0.7 |
0.571 |
5.01 |
-0.0295 |
0.384 |
-0.782 |
0.723 |
| 0.8 |
0.528 |
6.31 |
-0.0295 |
0.398 |
-0.810 |
0.751 |
| 0.9 |
0.472 |
7.94 |
-0.0295 |
0.429 |
-0.870 |
0.811 |
| 1.0 |
0.387 |
10.00 |
-0.0295 |
0.460 |
-0.932 |
0.873 |
| 1.1 |
0.347 |
12.60 |
-0.0295 |
0.472 |
-0.954 |
0.895 |
| 1.2 |
0.319 |
15.80 |
-0.0295 |
0.516 |
-1.040 |
0.981 |
| 1.3 |
0.259 |
20.00 |
-0.0295 |
0.558 |
-1.120 |
1.060 |
| 1.4 |
0.241 |
25.10 |
-0.0295 |
0.607 |
-1.220 |
1.160 |
| 1.5 |
0.195 |
31.60 |
-0.0295 |
0.903 |
-1.800 |
1.740 |
| 1.6 |
0.156 |
39.80 |
-0.0295 |
0.625 |
-1.250 |
1.200 |
| 1.7 |
0.147 |
50.10 |
-0.0295 |
0.630 |
-1.260 |
1.200 |
| 1.8 |
0.132 |
63.10 |
-0.0295 |
0.748 |
-1.500 |
1.440 |
| 1.9 |
0.128 |
79.40 |
-0.0295 |
0.715 |
-1.430 |
1.370 |
RV144 (24 month)
- Adjustment covariates: dem_sex, BRA_risk
- Event time variable: HIVwk26fu
- Event type variable: HIVwk26
- Weight variable: sample_weight
- Reference timepoint: 459 days
- All learners: GLM
IgG V1V2 B.CaseA-gp70
Monotone

| 0.0 |
1.000 |
1.00 |
0.00361 |
0.000724 |
0.002190 |
0.00503 |
| 0.1 |
0.995 |
1.26 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.2 |
0.995 |
1.58 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.3 |
0.995 |
2.00 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.4 |
0.994 |
2.51 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.5 |
0.994 |
3.16 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.6 |
0.994 |
3.98 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.7 |
0.994 |
5.01 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.8 |
0.992 |
6.31 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 0.9 |
0.992 |
7.94 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 1.0 |
0.989 |
10.00 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.1 |
0.988 |
12.60 |
0.00349 |
0.000761 |
0.002000 |
0.00498 |
| 1.2 |
0.982 |
15.80 |
0.00349 |
0.000766 |
0.001990 |
0.00499 |
| 1.3 |
0.974 |
20.00 |
0.00349 |
0.000770 |
0.001980 |
0.00500 |
| 1.4 |
0.972 |
25.10 |
0.00341 |
0.000754 |
0.001940 |
0.00489 |
| 1.5 |
0.967 |
31.60 |
0.00341 |
0.000757 |
0.001930 |
0.00490 |
| 1.6 |
0.959 |
39.80 |
0.00341 |
0.000763 |
0.001920 |
0.00491 |
| 1.7 |
0.955 |
50.10 |
0.00331 |
0.000748 |
0.001840 |
0.00477 |
| 1.8 |
0.934 |
63.10 |
0.00322 |
0.000747 |
0.001760 |
0.00469 |
| 1.9 |
0.933 |
79.40 |
0.00309 |
0.000729 |
0.001670 |
0.00452 |
| 2.0 |
0.920 |
100.00 |
0.00309 |
0.000737 |
0.001650 |
0.00454 |
| 2.1 |
0.907 |
126.00 |
0.00299 |
0.000726 |
0.001570 |
0.00442 |
| 2.2 |
0.882 |
158.00 |
0.00291 |
0.000724 |
0.001490 |
0.00433 |
| 2.3 |
0.828 |
200.00 |
0.00271 |
0.000716 |
0.001310 |
0.00411 |
| 2.4 |
0.790 |
251.00 |
0.00271 |
0.000733 |
0.001270 |
0.00415 |
| 2.5 |
0.731 |
316.00 |
0.00271 |
0.000771 |
0.001200 |
0.00422 |
| 2.6 |
0.674 |
398.00 |
0.00233 |
0.000741 |
0.000882 |
0.00379 |
| 2.7 |
0.617 |
501.00 |
0.00229 |
0.000764 |
0.000790 |
0.00379 |
| 2.8 |
0.522 |
631.00 |
0.00229 |
0.000842 |
0.000637 |
0.00394 |
| 2.9 |
0.487 |
794.00 |
0.00229 |
0.000918 |
0.000488 |
0.00409 |
| 3.0 |
0.411 |
1000.00 |
0.00229 |
0.001110 |
0.000116 |
0.00446 |
| 3.1 |
0.351 |
1260.00 |
0.00229 |
0.001250 |
-0.000163 |
0.00474 |
| 3.2 |
0.280 |
1580.00 |
0.00229 |
0.001440 |
-0.000532 |
0.00511 |
| 3.3 |
0.206 |
2000.00 |
0.00229 |
0.001740 |
-0.001130 |
0.00570 |
| 3.4 |
0.165 |
2510.00 |
0.00229 |
0.001450 |
-0.000557 |
0.00513 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.995 |
0.00348 |
0.000758 |
0.001990 |
0.00496 |
| 0.2 |
1.58 |
0.995 |
0.00348 |
0.000758 |
0.001990 |
0.00496 |
| 0.3 |
2.00 |
0.995 |
0.00348 |
0.000758 |
0.001990 |
0.00496 |
| 0.4 |
2.51 |
0.994 |
0.00348 |
0.000758 |
0.001990 |
0.00497 |
| 0.5 |
3.16 |
0.994 |
0.00348 |
0.000758 |
0.001990 |
0.00497 |
| 0.6 |
3.98 |
0.994 |
0.00348 |
0.000758 |
0.001990 |
0.00497 |
| 0.7 |
5.01 |
0.994 |
0.00348 |
0.000758 |
0.001990 |
0.00497 |
| 0.8 |
6.31 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 0.9 |
7.94 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 1.0 |
10.00 |
0.989 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.1 |
12.60 |
0.988 |
0.00349 |
0.000761 |
0.002000 |
0.00498 |
| 1.2 |
15.80 |
0.982 |
0.00351 |
0.000766 |
0.002010 |
0.00501 |
| 1.3 |
20.00 |
0.974 |
0.00354 |
0.000770 |
0.002030 |
0.00505 |
| 1.4 |
25.10 |
0.972 |
0.00340 |
0.000754 |
0.001920 |
0.00487 |
| 1.5 |
31.60 |
0.967 |
0.00341 |
0.000757 |
0.001920 |
0.00489 |
| 1.6 |
39.80 |
0.959 |
0.00344 |
0.000763 |
0.001940 |
0.00494 |
| 1.7 |
50.10 |
0.955 |
0.00331 |
0.000748 |
0.001840 |
0.00477 |
| 1.8 |
63.10 |
0.934 |
0.00322 |
0.000747 |
0.001760 |
0.00469 |
| 1.9 |
79.40 |
0.933 |
0.00308 |
0.000729 |
0.001650 |
0.00451 |
| 2.0 |
100.00 |
0.920 |
0.00311 |
0.000737 |
0.001670 |
0.00455 |
| 2.1 |
126.00 |
0.907 |
0.00299 |
0.000726 |
0.001570 |
0.00442 |
| 2.2 |
158.00 |
0.882 |
0.00291 |
0.000724 |
0.001490 |
0.00433 |
| 2.3 |
200.00 |
0.828 |
0.00271 |
0.000716 |
0.001310 |
0.00411 |
| 2.4 |
251.00 |
0.790 |
0.00269 |
0.000733 |
0.001250 |
0.00413 |
| 2.5 |
316.00 |
0.731 |
0.00273 |
0.000771 |
0.001220 |
0.00424 |
| 2.6 |
398.00 |
0.674 |
0.00233 |
0.000741 |
0.000882 |
0.00379 |
| 2.7 |
501.00 |
0.617 |
0.00228 |
0.000764 |
0.000787 |
0.00378 |
| 2.8 |
631.00 |
0.522 |
0.00239 |
0.000842 |
0.000738 |
0.00404 |
| 2.9 |
794.00 |
0.487 |
0.00260 |
0.000918 |
0.000804 |
0.00440 |
| 3.0 |
1000.00 |
0.411 |
0.00290 |
0.001110 |
0.000729 |
0.00507 |
| 3.1 |
1260.00 |
0.351 |
0.00322 |
0.001250 |
0.000774 |
0.00567 |
| 3.2 |
1580.00 |
0.280 |
0.00321 |
0.001440 |
0.000391 |
0.00603 |
| 3.3 |
2000.00 |
0.206 |
0.00301 |
0.001740 |
-0.000402 |
0.00643 |
| 3.4 |
2510.00 |
0.165 |
0.00239 |
0.001450 |
-0.000459 |
0.00523 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.220 |
0.214 |
-0.19900 |
0.638 |
| 0.1 |
0.995 |
1.26 |
0.246 |
0.216 |
-0.17600 |
0.669 |
| 0.2 |
0.995 |
1.58 |
0.246 |
0.216 |
-0.17600 |
0.669 |
| 0.3 |
0.995 |
2.00 |
0.246 |
0.216 |
-0.17600 |
0.669 |
| 0.4 |
0.994 |
2.51 |
0.246 |
0.216 |
-0.17700 |
0.669 |
| 0.5 |
0.994 |
3.16 |
0.246 |
0.216 |
-0.17700 |
0.669 |
| 0.6 |
0.994 |
3.98 |
0.246 |
0.216 |
-0.17700 |
0.669 |
| 0.7 |
0.994 |
5.01 |
0.246 |
0.216 |
-0.17700 |
0.669 |
| 0.8 |
0.992 |
6.31 |
0.246 |
0.216 |
-0.17700 |
0.669 |
| 0.9 |
0.992 |
7.94 |
0.246 |
0.216 |
-0.17700 |
0.669 |
| 1.0 |
0.989 |
10.00 |
0.246 |
0.216 |
-0.17700 |
0.670 |
| 1.1 |
0.988 |
12.60 |
0.246 |
0.216 |
-0.17800 |
0.670 |
| 1.2 |
0.982 |
15.80 |
0.246 |
0.217 |
-0.17900 |
0.672 |
| 1.3 |
0.974 |
20.00 |
0.246 |
0.218 |
-0.18100 |
0.673 |
| 1.4 |
0.972 |
25.10 |
0.262 |
0.213 |
-0.15600 |
0.680 |
| 1.5 |
0.967 |
31.60 |
0.262 |
0.214 |
-0.15700 |
0.681 |
| 1.6 |
0.959 |
39.80 |
0.262 |
0.215 |
-0.15900 |
0.683 |
| 1.7 |
0.955 |
50.10 |
0.286 |
0.209 |
-0.12500 |
0.696 |
| 1.8 |
0.934 |
63.10 |
0.303 |
0.207 |
-0.10300 |
0.709 |
| 1.9 |
0.933 |
79.40 |
0.331 |
0.201 |
-0.06200 |
0.725 |
| 2.0 |
0.920 |
100.00 |
0.331 |
0.202 |
-0.06470 |
0.728 |
| 2.1 |
0.907 |
126.00 |
0.353 |
0.198 |
-0.03440 |
0.741 |
| 2.2 |
0.882 |
158.00 |
0.372 |
0.195 |
-0.01120 |
0.755 |
| 2.3 |
0.828 |
200.00 |
0.415 |
0.189 |
0.04370 |
0.785 |
| 2.4 |
0.790 |
251.00 |
0.415 |
0.192 |
0.03770 |
0.791 |
| 2.5 |
0.731 |
316.00 |
0.415 |
0.199 |
0.02440 |
0.805 |
| 2.6 |
0.674 |
398.00 |
0.496 |
0.186 |
0.13200 |
0.859 |
| 2.7 |
0.617 |
501.00 |
0.506 |
0.189 |
0.13500 |
0.876 |
| 2.8 |
0.522 |
631.00 |
0.506 |
0.204 |
0.10600 |
0.905 |
| 2.9 |
0.487 |
794.00 |
0.506 |
0.219 |
0.07680 |
0.934 |
| 3.0 |
0.411 |
1000.00 |
0.506 |
0.257 |
0.00264 |
1.010 |
| 3.1 |
0.351 |
1260.00 |
0.506 |
0.285 |
-0.05390 |
1.070 |
| 3.2 |
0.280 |
1580.00 |
0.506 |
0.324 |
-0.13000 |
1.140 |
| 3.3 |
0.206 |
2000.00 |
0.506 |
0.388 |
-0.25400 |
1.270 |
| 3.4 |
0.165 |
2510.00 |
0.506 |
0.327 |
-0.13500 |
1.150 |
IgG V1V2 C.1086-gp70
Monotone

| 0.0 |
1.000 |
1.00 |
0.00362 |
0.000724 |
0.002200 |
0.00504 |
| 0.1 |
0.995 |
1.26 |
0.00362 |
0.000775 |
0.002100 |
0.00514 |
| 0.2 |
0.995 |
1.58 |
0.00362 |
0.000775 |
0.002100 |
0.00514 |
| 0.3 |
0.995 |
2.00 |
0.00362 |
0.000775 |
0.002100 |
0.00514 |
| 0.4 |
0.994 |
2.51 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 0.5 |
0.992 |
3.16 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 0.6 |
0.992 |
3.98 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 0.7 |
0.992 |
5.01 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 0.8 |
0.992 |
6.31 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 0.9 |
0.992 |
7.94 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 1.0 |
0.992 |
10.00 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 1.1 |
0.991 |
12.60 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.2 |
0.991 |
15.80 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.3 |
0.991 |
20.00 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.4 |
0.991 |
25.10 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.5 |
0.991 |
31.60 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.6 |
0.991 |
39.80 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.7 |
0.991 |
50.10 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.8 |
0.991 |
63.10 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.9 |
0.989 |
79.40 |
0.00349 |
0.000761 |
0.002000 |
0.00498 |
| 2.0 |
0.988 |
100.00 |
0.00349 |
0.000762 |
0.002000 |
0.00499 |
| 2.1 |
0.986 |
126.00 |
0.00349 |
0.000763 |
0.002000 |
0.00499 |
| 2.2 |
0.986 |
158.00 |
0.00349 |
0.000763 |
0.002000 |
0.00499 |
| 2.3 |
0.986 |
200.00 |
0.00349 |
0.000763 |
0.002000 |
0.00499 |
| 2.4 |
0.986 |
251.00 |
0.00349 |
0.000763 |
0.002000 |
0.00499 |
| 2.5 |
0.981 |
316.00 |
0.00349 |
0.000765 |
0.001990 |
0.00499 |
| 2.6 |
0.981 |
398.00 |
0.00349 |
0.000765 |
0.001990 |
0.00499 |
| 2.7 |
0.981 |
501.00 |
0.00343 |
0.000748 |
0.001960 |
0.00489 |
| 2.8 |
0.977 |
631.00 |
0.00343 |
0.000753 |
0.001950 |
0.00490 |
| 2.9 |
0.960 |
794.00 |
0.00343 |
0.000766 |
0.001920 |
0.00493 |
| 3.0 |
0.960 |
1000.00 |
0.00343 |
0.000766 |
0.001920 |
0.00493 |
| 3.1 |
0.956 |
1260.00 |
0.00343 |
0.000769 |
0.001920 |
0.00493 |
| 3.2 |
0.946 |
1580.00 |
0.00334 |
0.000756 |
0.001860 |
0.00482 |
| 3.3 |
0.928 |
2000.00 |
0.00308 |
0.000728 |
0.001650 |
0.00450 |
| 3.4 |
0.909 |
2510.00 |
0.00306 |
0.000727 |
0.001630 |
0.00449 |
| 3.5 |
0.889 |
3160.00 |
0.00306 |
0.000744 |
0.001600 |
0.00452 |
| 3.6 |
0.855 |
3980.00 |
0.00306 |
0.000751 |
0.001590 |
0.00453 |
| 3.7 |
0.767 |
5010.00 |
0.00306 |
0.000808 |
0.001480 |
0.00464 |
| 3.8 |
0.685 |
6310.00 |
0.00306 |
0.000800 |
0.001490 |
0.00463 |
| 3.9 |
0.593 |
7940.00 |
0.00306 |
0.000919 |
0.001260 |
0.00486 |
| 4.0 |
0.498 |
10000.00 |
0.00306 |
0.001140 |
0.000834 |
0.00529 |
| 4.1 |
0.410 |
12600.00 |
0.00306 |
0.001120 |
0.000865 |
0.00526 |
| 4.2 |
0.326 |
15800.00 |
0.00306 |
0.001290 |
0.000540 |
0.00558 |
| 4.3 |
0.240 |
20000.00 |
0.00306 |
0.001650 |
-0.000170 |
0.00629 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.995 |
0.00362 |
0.000775 |
0.002100 |
0.00514 |
| 0.2 |
1.58 |
0.995 |
0.00362 |
0.000775 |
0.002100 |
0.00514 |
| 0.3 |
2.00 |
0.995 |
0.00362 |
0.000775 |
0.002100 |
0.00514 |
| 0.4 |
2.51 |
0.994 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 0.5 |
3.16 |
0.992 |
0.00363 |
0.000776 |
0.002110 |
0.00515 |
| 0.6 |
3.98 |
0.992 |
0.00363 |
0.000776 |
0.002110 |
0.00515 |
| 0.7 |
5.01 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 0.8 |
6.31 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 0.9 |
7.94 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 1.0 |
10.00 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 1.1 |
12.60 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.2 |
15.80 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.3 |
20.00 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.4 |
25.10 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.5 |
31.60 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.6 |
39.80 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.7 |
50.10 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.8 |
63.10 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.9 |
79.40 |
0.989 |
0.00349 |
0.000761 |
0.002000 |
0.00499 |
| 2.0 |
100.00 |
0.988 |
0.00350 |
0.000762 |
0.002010 |
0.00499 |
| 2.1 |
126.00 |
0.986 |
0.00350 |
0.000763 |
0.002010 |
0.00500 |
| 2.2 |
158.00 |
0.986 |
0.00350 |
0.000763 |
0.002010 |
0.00500 |
| 2.3 |
200.00 |
0.986 |
0.00350 |
0.000763 |
0.002010 |
0.00500 |
| 2.4 |
251.00 |
0.986 |
0.00350 |
0.000763 |
0.002010 |
0.00500 |
| 2.5 |
316.00 |
0.981 |
0.00351 |
0.000765 |
0.002010 |
0.00501 |
| 2.6 |
398.00 |
0.981 |
0.00351 |
0.000765 |
0.002010 |
0.00501 |
| 2.7 |
501.00 |
0.981 |
0.00337 |
0.000748 |
0.001900 |
0.00483 |
| 2.8 |
631.00 |
0.977 |
0.00339 |
0.000753 |
0.001920 |
0.00487 |
| 2.9 |
794.00 |
0.960 |
0.00345 |
0.000766 |
0.001950 |
0.00496 |
| 3.0 |
1000.00 |
0.960 |
0.00345 |
0.000766 |
0.001950 |
0.00496 |
| 3.1 |
1260.00 |
0.956 |
0.00347 |
0.000769 |
0.001960 |
0.00497 |
| 3.2 |
1580.00 |
0.946 |
0.00334 |
0.000756 |
0.001860 |
0.00482 |
| 3.3 |
2000.00 |
0.928 |
0.00308 |
0.000728 |
0.001650 |
0.00450 |
| 3.4 |
2510.00 |
0.909 |
0.00300 |
0.000727 |
0.001570 |
0.00442 |
| 3.5 |
3160.00 |
0.889 |
0.00306 |
0.000744 |
0.001600 |
0.00452 |
| 3.6 |
3980.00 |
0.855 |
0.00301 |
0.000751 |
0.001540 |
0.00448 |
| 3.7 |
5010.00 |
0.767 |
0.00305 |
0.000808 |
0.001460 |
0.00463 |
| 3.8 |
6310.00 |
0.685 |
0.00273 |
0.000800 |
0.001160 |
0.00430 |
| 3.9 |
7940.00 |
0.593 |
0.00301 |
0.000919 |
0.001210 |
0.00481 |
| 4.0 |
10000.00 |
0.498 |
0.00366 |
0.001140 |
0.001430 |
0.00589 |
| 4.1 |
12600.00 |
0.410 |
0.00299 |
0.001120 |
0.000793 |
0.00518 |
| 4.2 |
15800.00 |
0.326 |
0.00315 |
0.001290 |
0.000632 |
0.00567 |
| 4.3 |
20000.00 |
0.240 |
0.00373 |
0.001650 |
0.000501 |
0.00696 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.217 |
0.214 |
-0.2020 |
0.636 |
| 0.1 |
0.995 |
1.26 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.2 |
0.995 |
1.58 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.3 |
0.995 |
2.00 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.4 |
0.994 |
2.51 |
0.217 |
0.222 |
-0.2180 |
0.653 |
| 0.5 |
0.992 |
3.16 |
0.217 |
0.222 |
-0.2180 |
0.653 |
| 0.6 |
0.992 |
3.98 |
0.217 |
0.222 |
-0.2180 |
0.653 |
| 0.7 |
0.992 |
5.01 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 0.8 |
0.992 |
6.31 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 0.9 |
0.992 |
7.94 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.0 |
0.992 |
10.00 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.1 |
0.991 |
12.60 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.2 |
0.991 |
15.80 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.3 |
0.991 |
20.00 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.4 |
0.991 |
25.10 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.5 |
0.991 |
31.60 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.6 |
0.991 |
39.80 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.7 |
0.991 |
50.10 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.8 |
0.991 |
63.10 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.9 |
0.989 |
79.40 |
0.246 |
0.216 |
-0.1790 |
0.670 |
| 2.0 |
0.988 |
100.00 |
0.246 |
0.216 |
-0.1790 |
0.670 |
| 2.1 |
0.986 |
126.00 |
0.246 |
0.217 |
-0.1790 |
0.670 |
| 2.2 |
0.986 |
158.00 |
0.246 |
0.217 |
-0.1790 |
0.670 |
| 2.3 |
0.986 |
200.00 |
0.246 |
0.217 |
-0.1790 |
0.670 |
| 2.4 |
0.986 |
251.00 |
0.246 |
0.217 |
-0.1790 |
0.670 |
| 2.5 |
0.981 |
316.00 |
0.246 |
0.217 |
-0.1800 |
0.671 |
| 2.6 |
0.981 |
398.00 |
0.246 |
0.217 |
-0.1800 |
0.671 |
| 2.7 |
0.981 |
501.00 |
0.259 |
0.212 |
-0.1570 |
0.676 |
| 2.8 |
0.977 |
631.00 |
0.259 |
0.213 |
-0.1580 |
0.677 |
| 2.9 |
0.960 |
794.00 |
0.259 |
0.215 |
-0.1630 |
0.682 |
| 3.0 |
0.960 |
1000.00 |
0.259 |
0.215 |
-0.1630 |
0.682 |
| 3.1 |
0.956 |
1260.00 |
0.259 |
0.216 |
-0.1640 |
0.683 |
| 3.2 |
0.946 |
1580.00 |
0.278 |
0.212 |
-0.1370 |
0.693 |
| 3.3 |
0.928 |
2000.00 |
0.335 |
0.200 |
-0.0572 |
0.728 |
| 3.4 |
0.909 |
2510.00 |
0.339 |
0.200 |
-0.0527 |
0.730 |
| 3.5 |
0.889 |
3160.00 |
0.339 |
0.202 |
-0.0582 |
0.736 |
| 3.6 |
0.855 |
3980.00 |
0.339 |
0.204 |
-0.0607 |
0.738 |
| 3.7 |
0.767 |
5010.00 |
0.339 |
0.214 |
-0.0802 |
0.757 |
| 3.8 |
0.685 |
6310.00 |
0.339 |
0.212 |
-0.0775 |
0.755 |
| 3.9 |
0.593 |
7940.00 |
0.339 |
0.234 |
-0.1190 |
0.797 |
| 4.0 |
0.498 |
10000.00 |
0.339 |
0.275 |
-0.2000 |
0.877 |
| 4.1 |
0.410 |
12600.00 |
0.339 |
0.272 |
-0.1940 |
0.871 |
| 4.2 |
0.326 |
15800.00 |
0.339 |
0.304 |
-0.2570 |
0.934 |
| 4.3 |
0.240 |
20000.00 |
0.339 |
0.377 |
-0.4000 |
1.080 |
IgG3 V1V2 B.CaseA-gp70
Monotone

| 0.0 |
1.000 |
1.00 |
0.00361 |
0.000724 |
0.002190 |
0.00503 |
| 0.1 |
0.976 |
1.26 |
0.00341 |
0.000755 |
0.001930 |
0.00489 |
| 0.2 |
0.972 |
1.58 |
0.00341 |
0.000758 |
0.001930 |
0.00490 |
| 0.3 |
0.972 |
2.00 |
0.00341 |
0.000758 |
0.001930 |
0.00490 |
| 0.4 |
0.948 |
2.51 |
0.00339 |
0.000757 |
0.001900 |
0.00487 |
| 0.5 |
0.948 |
3.16 |
0.00339 |
0.000757 |
0.001900 |
0.00487 |
| 0.6 |
0.932 |
3.98 |
0.00339 |
0.000769 |
0.001880 |
0.00489 |
| 0.7 |
0.921 |
5.01 |
0.00339 |
0.000777 |
0.001860 |
0.00491 |
| 0.8 |
0.921 |
6.31 |
0.00339 |
0.000777 |
0.001860 |
0.00491 |
| 0.9 |
0.913 |
7.94 |
0.00335 |
0.000764 |
0.001860 |
0.00485 |
| 1.0 |
0.882 |
10.00 |
0.00335 |
0.000789 |
0.001810 |
0.00490 |
| 1.1 |
0.824 |
12.60 |
0.00335 |
0.000790 |
0.001810 |
0.00490 |
| 1.2 |
0.792 |
15.80 |
0.00335 |
0.000821 |
0.001740 |
0.00496 |
| 1.3 |
0.754 |
20.00 |
0.00335 |
0.000835 |
0.001720 |
0.00499 |
| 1.4 |
0.715 |
25.10 |
0.00335 |
0.000881 |
0.001630 |
0.00508 |
| 1.5 |
0.666 |
31.60 |
0.00335 |
0.000904 |
0.001580 |
0.00513 |
| 1.6 |
0.614 |
39.80 |
0.00324 |
0.000920 |
0.001440 |
0.00504 |
| 1.7 |
0.517 |
50.10 |
0.00324 |
0.001000 |
0.001280 |
0.00521 |
| 1.8 |
0.475 |
63.10 |
0.00324 |
0.001040 |
0.001190 |
0.00529 |
| 1.9 |
0.400 |
79.40 |
0.00316 |
0.001080 |
0.001040 |
0.00529 |
| 2.0 |
0.330 |
100.00 |
0.00316 |
0.001080 |
0.001040 |
0.00528 |
| 2.1 |
0.284 |
126.00 |
0.00316 |
0.001240 |
0.000727 |
0.00560 |
| 2.2 |
0.232 |
158.00 |
0.00316 |
0.001540 |
0.000139 |
0.00619 |
| 2.3 |
0.206 |
200.00 |
0.00316 |
0.001520 |
0.000189 |
0.00614 |
| 2.4 |
0.162 |
251.00 |
0.00316 |
0.002080 |
-0.000907 |
0.00724 |
| 2.5 |
0.132 |
316.00 |
0.00316 |
0.002880 |
-0.002490 |
0.00882 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.976 |
0.00341 |
0.000755 |
0.001930 |
0.00489 |
| 0.2 |
1.58 |
0.972 |
0.00342 |
0.000758 |
0.001930 |
0.00490 |
| 0.3 |
2.00 |
0.972 |
0.00342 |
0.000758 |
0.001930 |
0.00490 |
| 0.4 |
2.51 |
0.948 |
0.00334 |
0.000757 |
0.001860 |
0.00482 |
| 0.5 |
3.16 |
0.948 |
0.00334 |
0.000757 |
0.001860 |
0.00482 |
| 0.6 |
3.98 |
0.932 |
0.00339 |
0.000769 |
0.001890 |
0.00490 |
| 0.7 |
5.01 |
0.921 |
0.00343 |
0.000777 |
0.001900 |
0.00495 |
| 0.8 |
6.31 |
0.921 |
0.00343 |
0.000777 |
0.001900 |
0.00495 |
| 0.9 |
7.94 |
0.913 |
0.00330 |
0.000764 |
0.001800 |
0.00479 |
| 1.0 |
10.00 |
0.882 |
0.00340 |
0.000789 |
0.001850 |
0.00495 |
| 1.1 |
12.60 |
0.824 |
0.00324 |
0.000790 |
0.001690 |
0.00479 |
| 1.2 |
15.80 |
0.792 |
0.00336 |
0.000821 |
0.001750 |
0.00497 |
| 1.3 |
20.00 |
0.754 |
0.00332 |
0.000835 |
0.001680 |
0.00496 |
| 1.4 |
25.10 |
0.715 |
0.00349 |
0.000881 |
0.001770 |
0.00522 |
| 1.5 |
31.60 |
0.666 |
0.00338 |
0.000904 |
0.001610 |
0.00516 |
| 1.6 |
39.80 |
0.614 |
0.00323 |
0.000920 |
0.001420 |
0.00503 |
| 1.7 |
50.10 |
0.517 |
0.00326 |
0.001000 |
0.001290 |
0.00522 |
| 1.8 |
63.10 |
0.475 |
0.00324 |
0.001040 |
0.001190 |
0.00529 |
| 1.9 |
79.40 |
0.400 |
0.00289 |
0.001080 |
0.000762 |
0.00501 |
| 2.0 |
100.00 |
0.330 |
0.00229 |
0.001080 |
0.000171 |
0.00441 |
| 2.1 |
126.00 |
0.284 |
0.00263 |
0.001240 |
0.000191 |
0.00507 |
| 2.2 |
158.00 |
0.232 |
0.00323 |
0.001540 |
0.000202 |
0.00625 |
| 2.3 |
200.00 |
0.206 |
0.00285 |
0.001520 |
-0.000122 |
0.00583 |
| 2.4 |
251.00 |
0.162 |
0.00379 |
0.002080 |
-0.000282 |
0.00786 |
| 2.5 |
316.00 |
0.132 |
0.00448 |
0.002880 |
-0.001180 |
0.01010 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.220 |
0.214 |
-0.199 |
0.638 |
| 0.1 |
0.976 |
1.26 |
0.262 |
0.213 |
-0.156 |
0.680 |
| 0.2 |
0.972 |
1.58 |
0.262 |
0.214 |
-0.157 |
0.681 |
| 0.3 |
0.972 |
2.00 |
0.262 |
0.214 |
-0.157 |
0.681 |
| 0.4 |
0.948 |
2.51 |
0.268 |
0.213 |
-0.149 |
0.686 |
| 0.5 |
0.948 |
3.16 |
0.268 |
0.213 |
-0.149 |
0.686 |
| 0.6 |
0.932 |
3.98 |
0.268 |
0.215 |
-0.153 |
0.690 |
| 0.7 |
0.921 |
5.01 |
0.268 |
0.216 |
-0.155 |
0.692 |
| 0.8 |
0.921 |
6.31 |
0.268 |
0.216 |
-0.155 |
0.692 |
| 0.9 |
0.913 |
7.94 |
0.275 |
0.213 |
-0.143 |
0.693 |
| 1.0 |
0.882 |
10.00 |
0.275 |
0.217 |
-0.151 |
0.701 |
| 1.1 |
0.824 |
12.60 |
0.275 |
0.218 |
-0.151 |
0.702 |
| 1.2 |
0.792 |
15.80 |
0.275 |
0.223 |
-0.162 |
0.712 |
| 1.3 |
0.754 |
20.00 |
0.275 |
0.225 |
-0.167 |
0.717 |
| 1.4 |
0.715 |
25.10 |
0.275 |
0.233 |
-0.182 |
0.733 |
| 1.5 |
0.666 |
31.60 |
0.275 |
0.238 |
-0.190 |
0.741 |
| 1.6 |
0.614 |
39.80 |
0.299 |
0.238 |
-0.167 |
0.765 |
| 1.7 |
0.517 |
50.10 |
0.299 |
0.253 |
-0.196 |
0.795 |
| 1.8 |
0.475 |
63.10 |
0.300 |
0.261 |
-0.211 |
0.811 |
| 1.9 |
0.400 |
79.40 |
0.316 |
0.267 |
-0.206 |
0.839 |
| 2.0 |
0.330 |
100.00 |
0.316 |
0.266 |
-0.206 |
0.838 |
| 2.1 |
0.284 |
126.00 |
0.316 |
0.297 |
-0.267 |
0.899 |
| 2.2 |
0.232 |
158.00 |
0.316 |
0.357 |
-0.384 |
1.020 |
| 2.3 |
0.206 |
200.00 |
0.316 |
0.352 |
-0.374 |
1.010 |
| 2.4 |
0.162 |
251.00 |
0.316 |
0.467 |
-0.599 |
1.230 |
| 2.5 |
0.132 |
316.00 |
0.316 |
0.636 |
-0.931 |
1.560 |
IgG3 V1V2 C.1086-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00361 |
0.000724 |
2.19e-03 |
0.00503 |
| 0.1 |
0.9840 |
1.26 |
0.00355 |
0.000765 |
2.05e-03 |
0.00505 |
| 0.2 |
0.9840 |
1.58 |
0.00355 |
0.000765 |
2.05e-03 |
0.00505 |
| 0.3 |
0.9840 |
2.00 |
0.00355 |
0.000765 |
2.05e-03 |
0.00505 |
| 0.4 |
0.9790 |
2.51 |
0.00355 |
0.000768 |
2.04e-03 |
0.00505 |
| 0.5 |
0.9770 |
3.16 |
0.00355 |
0.000768 |
2.04e-03 |
0.00505 |
| 0.6 |
0.9770 |
3.98 |
0.00355 |
0.000768 |
2.04e-03 |
0.00505 |
| 0.7 |
0.9720 |
5.01 |
0.00355 |
0.000773 |
2.03e-03 |
0.00506 |
| 0.8 |
0.9650 |
6.31 |
0.00355 |
0.000777 |
2.02e-03 |
0.00507 |
| 0.9 |
0.9650 |
7.94 |
0.00355 |
0.000777 |
2.02e-03 |
0.00507 |
| 1.0 |
0.9590 |
10.00 |
0.00355 |
0.000782 |
2.02e-03 |
0.00508 |
| 1.1 |
0.9510 |
12.60 |
0.00355 |
0.000788 |
2.00e-03 |
0.00509 |
| 1.2 |
0.9480 |
15.80 |
0.00348 |
0.000772 |
1.96e-03 |
0.00499 |
| 1.3 |
0.9470 |
20.00 |
0.00336 |
0.000753 |
1.88e-03 |
0.00484 |
| 1.4 |
0.9410 |
25.10 |
0.00336 |
0.000756 |
1.88e-03 |
0.00484 |
| 1.5 |
0.9190 |
31.60 |
0.00336 |
0.000775 |
1.84e-03 |
0.00488 |
| 1.6 |
0.9070 |
39.80 |
0.00335 |
0.000766 |
1.85e-03 |
0.00485 |
| 1.7 |
0.8850 |
50.10 |
0.00335 |
0.000788 |
1.81e-03 |
0.00489 |
| 1.8 |
0.8690 |
63.10 |
0.00327 |
0.000759 |
1.78e-03 |
0.00475 |
| 1.9 |
0.8690 |
79.40 |
0.00327 |
0.000759 |
1.78e-03 |
0.00475 |
| 2.0 |
0.8370 |
100.00 |
0.00327 |
0.000761 |
1.77e-03 |
0.00476 |
| 2.1 |
0.7940 |
126.00 |
0.00327 |
0.000786 |
1.73e-03 |
0.00481 |
| 2.2 |
0.7390 |
158.00 |
0.00327 |
0.000819 |
1.66e-03 |
0.00487 |
| 2.3 |
0.6800 |
200.00 |
0.00327 |
0.000843 |
1.61e-03 |
0.00492 |
| 2.4 |
0.6430 |
251.00 |
0.00327 |
0.000887 |
1.53e-03 |
0.00501 |
| 2.5 |
0.5840 |
316.00 |
0.00327 |
0.000970 |
1.37e-03 |
0.00517 |
| 2.6 |
0.5210 |
398.00 |
0.00327 |
0.001010 |
1.29e-03 |
0.00524 |
| 2.7 |
0.4470 |
501.00 |
0.00327 |
0.001180 |
9.55e-04 |
0.00558 |
| 2.8 |
0.3610 |
631.00 |
0.00327 |
0.001510 |
3.12e-04 |
0.00622 |
| 2.9 |
0.2960 |
794.00 |
0.00327 |
0.001660 |
2.18e-05 |
0.00651 |
| 3.0 |
0.2490 |
1000.00 |
0.00327 |
0.001980 |
-6.09e-04 |
0.00714 |
| 3.1 |
0.2030 |
1260.00 |
0.00327 |
0.002240 |
-1.12e-03 |
0.00765 |
| 3.2 |
0.1500 |
1580.00 |
0.00327 |
0.002330 |
-1.30e-03 |
0.00784 |
| 3.3 |
0.1200 |
2000.00 |
0.00327 |
0.002490 |
-1.62e-03 |
0.00816 |
| 3.4 |
0.0937 |
2510.00 |
0.00327 |
0.003900 |
-4.39e-03 |
0.01090 |
| 3.5 |
0.0656 |
3160.00 |
0.00327 |
0.006600 |
-9.66e-03 |
0.01620 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.9840 |
0.00352 |
0.000765 |
0.002020 |
0.00501 |
| 0.2 |
1.58 |
0.9840 |
0.00352 |
0.000765 |
0.002020 |
0.00501 |
| 0.3 |
2.00 |
0.9840 |
0.00352 |
0.000765 |
0.002020 |
0.00501 |
| 0.4 |
2.51 |
0.9790 |
0.00353 |
0.000768 |
0.002020 |
0.00503 |
| 0.5 |
3.16 |
0.9770 |
0.00353 |
0.000768 |
0.002020 |
0.00503 |
| 0.6 |
3.98 |
0.9770 |
0.00353 |
0.000768 |
0.002020 |
0.00503 |
| 0.7 |
5.01 |
0.9720 |
0.00355 |
0.000773 |
0.002030 |
0.00506 |
| 0.8 |
6.31 |
0.9650 |
0.00357 |
0.000777 |
0.002040 |
0.00509 |
| 0.9 |
7.94 |
0.9650 |
0.00357 |
0.000777 |
0.002040 |
0.00509 |
| 1.0 |
10.00 |
0.9590 |
0.00359 |
0.000782 |
0.002060 |
0.00512 |
| 1.1 |
12.60 |
0.9510 |
0.00362 |
0.000788 |
0.002070 |
0.00516 |
| 1.2 |
15.80 |
0.9480 |
0.00348 |
0.000772 |
0.001960 |
0.00499 |
| 1.3 |
20.00 |
0.9470 |
0.00333 |
0.000753 |
0.001850 |
0.00480 |
| 1.4 |
25.10 |
0.9410 |
0.00334 |
0.000756 |
0.001860 |
0.00482 |
| 1.5 |
31.60 |
0.9190 |
0.00342 |
0.000775 |
0.001900 |
0.00493 |
| 1.6 |
39.80 |
0.9070 |
0.00331 |
0.000766 |
0.001800 |
0.00481 |
| 1.7 |
50.10 |
0.8850 |
0.00339 |
0.000788 |
0.001850 |
0.00494 |
| 1.8 |
63.10 |
0.8690 |
0.00312 |
0.000759 |
0.001630 |
0.00461 |
| 1.9 |
79.40 |
0.8690 |
0.00312 |
0.000759 |
0.001630 |
0.00461 |
| 2.0 |
100.00 |
0.8370 |
0.00305 |
0.000761 |
0.001560 |
0.00454 |
| 2.1 |
126.00 |
0.7940 |
0.00305 |
0.000786 |
0.001510 |
0.00460 |
| 2.2 |
158.00 |
0.7390 |
0.00308 |
0.000819 |
0.001480 |
0.00469 |
| 2.3 |
200.00 |
0.6800 |
0.00297 |
0.000843 |
0.001310 |
0.00462 |
| 2.4 |
251.00 |
0.6430 |
0.00312 |
0.000887 |
0.001380 |
0.00486 |
| 2.5 |
316.00 |
0.5840 |
0.00340 |
0.000970 |
0.001500 |
0.00530 |
| 2.6 |
398.00 |
0.5210 |
0.00328 |
0.001010 |
0.001300 |
0.00525 |
| 2.7 |
501.00 |
0.4470 |
0.00366 |
0.001180 |
0.001340 |
0.00597 |
| 2.8 |
631.00 |
0.3610 |
0.00458 |
0.001510 |
0.001630 |
0.00754 |
| 2.9 |
794.00 |
0.2960 |
0.00453 |
0.001660 |
0.001280 |
0.00777 |
| 3.0 |
1000.00 |
0.2490 |
0.00464 |
0.001980 |
0.000768 |
0.00852 |
| 3.1 |
1260.00 |
0.2030 |
0.00528 |
0.002240 |
0.000896 |
0.00967 |
| 3.2 |
1580.00 |
0.1500 |
0.00429 |
0.002330 |
-0.000284 |
0.00886 |
| 3.3 |
2000.00 |
0.1200 |
0.00453 |
0.002490 |
-0.000354 |
0.00942 |
| 3.4 |
2510.00 |
0.0937 |
0.00681 |
0.003900 |
-0.000840 |
0.01450 |
| 3.5 |
3160.00 |
0.0656 |
0.01110 |
0.006600 |
-0.001830 |
0.02400 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.220 |
0.214 |
-0.199 |
0.638 |
| 0.1 |
0.9840 |
1.26 |
0.233 |
0.218 |
-0.195 |
0.662 |
| 0.2 |
0.9840 |
1.58 |
0.233 |
0.218 |
-0.195 |
0.662 |
| 0.3 |
0.9840 |
2.00 |
0.233 |
0.218 |
-0.195 |
0.662 |
| 0.4 |
0.9790 |
2.51 |
0.233 |
0.219 |
-0.195 |
0.662 |
| 0.5 |
0.9770 |
3.16 |
0.233 |
0.219 |
-0.196 |
0.663 |
| 0.6 |
0.9770 |
3.98 |
0.233 |
0.219 |
-0.196 |
0.663 |
| 0.7 |
0.9720 |
5.01 |
0.233 |
0.220 |
-0.197 |
0.664 |
| 0.8 |
0.9650 |
6.31 |
0.233 |
0.220 |
-0.199 |
0.666 |
| 0.9 |
0.9650 |
7.94 |
0.233 |
0.220 |
-0.199 |
0.666 |
| 1.0 |
0.9590 |
10.00 |
0.233 |
0.221 |
-0.200 |
0.667 |
| 1.1 |
0.9510 |
12.60 |
0.233 |
0.222 |
-0.202 |
0.669 |
| 1.2 |
0.9480 |
15.80 |
0.249 |
0.218 |
-0.178 |
0.675 |
| 1.3 |
0.9470 |
20.00 |
0.274 |
0.212 |
-0.141 |
0.689 |
| 1.4 |
0.9410 |
25.10 |
0.274 |
0.212 |
-0.142 |
0.689 |
| 1.5 |
0.9190 |
31.60 |
0.274 |
0.215 |
-0.148 |
0.696 |
| 1.6 |
0.9070 |
39.80 |
0.276 |
0.213 |
-0.142 |
0.694 |
| 1.7 |
0.8850 |
50.10 |
0.276 |
0.217 |
-0.150 |
0.702 |
| 1.8 |
0.8690 |
63.10 |
0.294 |
0.210 |
-0.118 |
0.706 |
| 1.9 |
0.8690 |
79.40 |
0.294 |
0.210 |
-0.118 |
0.706 |
| 2.0 |
0.8370 |
100.00 |
0.294 |
0.211 |
-0.119 |
0.707 |
| 2.1 |
0.7940 |
126.00 |
0.294 |
0.215 |
-0.127 |
0.715 |
| 2.2 |
0.7390 |
158.00 |
0.294 |
0.220 |
-0.138 |
0.726 |
| 2.3 |
0.6800 |
200.00 |
0.294 |
0.225 |
-0.146 |
0.734 |
| 2.4 |
0.6430 |
251.00 |
0.294 |
0.232 |
-0.162 |
0.750 |
| 2.5 |
0.5840 |
316.00 |
0.294 |
0.247 |
-0.191 |
0.779 |
| 2.6 |
0.5210 |
398.00 |
0.294 |
0.255 |
-0.205 |
0.793 |
| 2.7 |
0.4470 |
501.00 |
0.294 |
0.287 |
-0.268 |
0.856 |
| 2.8 |
0.3610 |
631.00 |
0.294 |
0.351 |
-0.394 |
0.983 |
| 2.9 |
0.2960 |
794.00 |
0.294 |
0.381 |
-0.453 |
1.040 |
| 3.0 |
0.2490 |
1000.00 |
0.294 |
0.447 |
-0.582 |
1.170 |
| 3.1 |
0.2030 |
1260.00 |
0.294 |
0.501 |
-0.688 |
1.280 |
| 3.2 |
0.1500 |
1580.00 |
0.294 |
0.521 |
-0.727 |
1.310 |
| 3.3 |
0.1200 |
2000.00 |
0.294 |
0.555 |
-0.793 |
1.380 |
| 3.4 |
0.0937 |
2510.00 |
0.294 |
0.854 |
-1.380 |
1.970 |
| 3.5 |
0.0656 |
3160.00 |
0.294 |
1.430 |
-2.510 |
3.100 |
IgG_V1V2_CaseA2_elisa
Monotone

| -0.903 |
1.000 |
0.125 |
0.00361 |
0.000724 |
2.19e-03 |
0.00503 |
| -0.803 |
0.980 |
0.157 |
0.00352 |
0.000766 |
2.02e-03 |
0.00502 |
| -0.703 |
0.914 |
0.198 |
0.00346 |
0.000785 |
1.92e-03 |
0.00500 |
| -0.603 |
0.783 |
0.249 |
0.00315 |
0.000809 |
1.56e-03 |
0.00473 |
| -0.503 |
0.672 |
0.314 |
0.00236 |
0.000746 |
8.96e-04 |
0.00382 |
| -0.403 |
0.486 |
0.395 |
0.00234 |
0.000849 |
6.72e-04 |
0.00400 |
| -0.303 |
0.330 |
0.498 |
0.00234 |
0.001210 |
-2.56e-05 |
0.00470 |
Not Monotone

| -0.903 |
0.125 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| -0.803 |
0.157 |
0.980 |
0.00352 |
0.000766 |
0.002020 |
0.00502 |
| -0.703 |
0.198 |
0.914 |
0.00346 |
0.000785 |
0.001920 |
0.00500 |
| -0.603 |
0.249 |
0.783 |
0.00315 |
0.000809 |
0.001560 |
0.00473 |
| -0.503 |
0.314 |
0.672 |
0.00236 |
0.000746 |
0.000896 |
0.00382 |
| -0.403 |
0.395 |
0.486 |
0.00215 |
0.000849 |
0.000481 |
0.00381 |
| -0.303 |
0.498 |
0.330 |
0.00253 |
0.001210 |
0.000166 |
0.00489 |
Vaccine efficacy (monotone)

| -0.903 |
1.000 |
0.125 |
0.220 |
0.214 |
-0.1990 |
0.638 |
| -0.803 |
0.980 |
0.157 |
0.239 |
0.218 |
-0.1870 |
0.666 |
| -0.703 |
0.914 |
0.198 |
0.252 |
0.220 |
-0.1780 |
0.682 |
| -0.603 |
0.783 |
0.249 |
0.320 |
0.216 |
-0.1030 |
0.743 |
| -0.503 |
0.672 |
0.314 |
0.491 |
0.187 |
0.1240 |
0.857 |
| -0.403 |
0.486 |
0.395 |
0.495 |
0.206 |
0.0908 |
0.899 |
| -0.303 |
0.330 |
0.498 |
0.495 |
0.277 |
-0.0478 |
1.040 |
IgG_gp70.V1V2CaseA2
Monotone

| 0.0 |
1.000 |
1.00 |
0.00361 |
0.000724 |
0.002190 |
0.00503 |
| 0.1 |
0.995 |
1.26 |
0.00349 |
0.000757 |
0.002010 |
0.00498 |
| 0.2 |
0.995 |
1.58 |
0.00349 |
0.000757 |
0.002010 |
0.00498 |
| 0.3 |
0.995 |
2.00 |
0.00349 |
0.000757 |
0.002010 |
0.00498 |
| 0.4 |
0.994 |
2.51 |
0.00349 |
0.000758 |
0.002010 |
0.00498 |
| 0.5 |
0.994 |
3.16 |
0.00349 |
0.000758 |
0.002010 |
0.00498 |
| 0.6 |
0.985 |
3.98 |
0.00349 |
0.000764 |
0.002000 |
0.00499 |
| 0.7 |
0.985 |
5.01 |
0.00349 |
0.000764 |
0.002000 |
0.00499 |
| 0.8 |
0.985 |
6.31 |
0.00349 |
0.000764 |
0.002000 |
0.00499 |
| 0.9 |
0.985 |
7.94 |
0.00349 |
0.000764 |
0.002000 |
0.00499 |
| 1.0 |
0.978 |
10.00 |
0.00349 |
0.000768 |
0.001990 |
0.00500 |
| 1.1 |
0.972 |
12.60 |
0.00342 |
0.000754 |
0.001940 |
0.00489 |
| 1.2 |
0.963 |
15.80 |
0.00342 |
0.000761 |
0.001920 |
0.00491 |
| 1.3 |
0.957 |
20.00 |
0.00330 |
0.000746 |
0.001830 |
0.00476 |
| 1.4 |
0.945 |
25.10 |
0.00319 |
0.000738 |
0.001740 |
0.00463 |
| 1.5 |
0.930 |
31.60 |
0.00310 |
0.000730 |
0.001670 |
0.00453 |
| 1.6 |
0.922 |
39.80 |
0.00310 |
0.000733 |
0.001670 |
0.00454 |
| 1.7 |
0.914 |
50.10 |
0.00310 |
0.000742 |
0.001650 |
0.00456 |
| 1.8 |
0.895 |
63.10 |
0.00291 |
0.000718 |
0.001510 |
0.00432 |
| 1.9 |
0.855 |
79.40 |
0.00291 |
0.000729 |
0.001490 |
0.00434 |
| 2.0 |
0.805 |
100.00 |
0.00291 |
0.000776 |
0.001390 |
0.00444 |
| 2.1 |
0.741 |
126.00 |
0.00263 |
0.000743 |
0.001170 |
0.00409 |
| 2.2 |
0.681 |
158.00 |
0.00250 |
0.000760 |
0.001010 |
0.00399 |
| 2.3 |
0.653 |
200.00 |
0.00242 |
0.000771 |
0.000913 |
0.00393 |
| 2.4 |
0.591 |
251.00 |
0.00212 |
0.000710 |
0.000727 |
0.00351 |
| 2.5 |
0.520 |
316.00 |
0.00212 |
0.000824 |
0.000503 |
0.00373 |
| 2.6 |
0.456 |
398.00 |
0.00212 |
0.000842 |
0.000468 |
0.00377 |
| 2.7 |
0.375 |
501.00 |
0.00212 |
0.000957 |
0.000242 |
0.00399 |
| 2.8 |
0.293 |
631.00 |
0.00191 |
0.001010 |
-0.000080 |
0.00390 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
2.10e-03 |
0.00513 |
| 0.1 |
1.26 |
0.995 |
0.00348 |
0.000757 |
1.99e-03 |
0.00496 |
| 0.2 |
1.58 |
0.995 |
0.00348 |
0.000757 |
1.99e-03 |
0.00496 |
| 0.3 |
2.00 |
0.995 |
0.00348 |
0.000757 |
1.99e-03 |
0.00496 |
| 0.4 |
2.51 |
0.994 |
0.00348 |
0.000758 |
1.99e-03 |
0.00497 |
| 0.5 |
3.16 |
0.994 |
0.00348 |
0.000758 |
1.99e-03 |
0.00497 |
| 0.6 |
3.98 |
0.985 |
0.00351 |
0.000764 |
2.01e-03 |
0.00501 |
| 0.7 |
5.01 |
0.985 |
0.00351 |
0.000764 |
2.01e-03 |
0.00501 |
| 0.8 |
6.31 |
0.985 |
0.00351 |
0.000764 |
2.01e-03 |
0.00501 |
| 0.9 |
7.94 |
0.985 |
0.00351 |
0.000764 |
2.01e-03 |
0.00501 |
| 1.0 |
10.00 |
0.978 |
0.00353 |
0.000768 |
2.02e-03 |
0.00503 |
| 1.1 |
12.60 |
0.972 |
0.00340 |
0.000754 |
1.92e-03 |
0.00487 |
| 1.2 |
15.80 |
0.963 |
0.00343 |
0.000761 |
1.94e-03 |
0.00493 |
| 1.3 |
20.00 |
0.957 |
0.00330 |
0.000746 |
1.83e-03 |
0.00476 |
| 1.4 |
25.10 |
0.945 |
0.00319 |
0.000738 |
1.74e-03 |
0.00463 |
| 1.5 |
31.60 |
0.930 |
0.00308 |
0.000730 |
1.65e-03 |
0.00452 |
| 1.6 |
39.80 |
0.922 |
0.00309 |
0.000733 |
1.66e-03 |
0.00453 |
| 1.7 |
50.10 |
0.914 |
0.00313 |
0.000742 |
1.68e-03 |
0.00458 |
| 1.8 |
63.10 |
0.895 |
0.00288 |
0.000718 |
1.48e-03 |
0.00429 |
| 1.9 |
79.40 |
0.855 |
0.00285 |
0.000729 |
1.42e-03 |
0.00428 |
| 2.0 |
100.00 |
0.805 |
0.00302 |
0.000776 |
1.50e-03 |
0.00454 |
| 2.1 |
126.00 |
0.741 |
0.00263 |
0.000743 |
1.17e-03 |
0.00409 |
| 2.2 |
158.00 |
0.681 |
0.00250 |
0.000760 |
1.01e-03 |
0.00399 |
| 2.3 |
200.00 |
0.653 |
0.00242 |
0.000771 |
9.13e-04 |
0.00393 |
| 2.4 |
251.00 |
0.591 |
0.00192 |
0.000710 |
5.27e-04 |
0.00331 |
| 2.5 |
316.00 |
0.520 |
0.00222 |
0.000824 |
6.05e-04 |
0.00384 |
| 2.6 |
398.00 |
0.456 |
0.00212 |
0.000842 |
4.71e-04 |
0.00377 |
| 2.7 |
501.00 |
0.375 |
0.00221 |
0.000957 |
3.38e-04 |
0.00409 |
| 2.8 |
631.00 |
0.293 |
0.00191 |
0.001010 |
-7.99e-05 |
0.00390 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.220 |
0.214 |
-0.1990 |
0.638 |
| 0.1 |
0.995 |
1.26 |
0.245 |
0.216 |
-0.1780 |
0.668 |
| 0.2 |
0.995 |
1.58 |
0.245 |
0.216 |
-0.1780 |
0.668 |
| 0.3 |
0.995 |
2.00 |
0.245 |
0.216 |
-0.1780 |
0.668 |
| 0.4 |
0.994 |
2.51 |
0.245 |
0.216 |
-0.1780 |
0.668 |
| 0.5 |
0.994 |
3.16 |
0.245 |
0.216 |
-0.1780 |
0.668 |
| 0.6 |
0.985 |
3.98 |
0.245 |
0.217 |
-0.1800 |
0.670 |
| 0.7 |
0.985 |
5.01 |
0.245 |
0.217 |
-0.1800 |
0.670 |
| 0.8 |
0.985 |
6.31 |
0.245 |
0.217 |
-0.1800 |
0.670 |
| 0.9 |
0.985 |
7.94 |
0.245 |
0.217 |
-0.1800 |
0.670 |
| 1.0 |
0.978 |
10.00 |
0.245 |
0.218 |
-0.1820 |
0.671 |
| 1.1 |
0.972 |
12.60 |
0.262 |
0.213 |
-0.1560 |
0.680 |
| 1.2 |
0.963 |
15.80 |
0.262 |
0.214 |
-0.1580 |
0.682 |
| 1.3 |
0.957 |
20.00 |
0.288 |
0.209 |
-0.1210 |
0.697 |
| 1.4 |
0.945 |
25.10 |
0.311 |
0.205 |
-0.0900 |
0.712 |
| 1.5 |
0.930 |
31.60 |
0.329 |
0.201 |
-0.0649 |
0.724 |
| 1.6 |
0.922 |
39.80 |
0.329 |
0.202 |
-0.0658 |
0.725 |
| 1.7 |
0.914 |
50.10 |
0.329 |
0.203 |
-0.0687 |
0.728 |
| 1.8 |
0.895 |
63.10 |
0.370 |
0.195 |
-0.0110 |
0.751 |
| 1.9 |
0.855 |
79.40 |
0.370 |
0.196 |
-0.0147 |
0.755 |
| 2.0 |
0.805 |
100.00 |
0.370 |
0.205 |
-0.0309 |
0.771 |
| 2.1 |
0.741 |
126.00 |
0.432 |
0.192 |
0.0549 |
0.808 |
| 2.2 |
0.681 |
158.00 |
0.461 |
0.192 |
0.0834 |
0.838 |
| 2.3 |
0.653 |
200.00 |
0.476 |
0.193 |
0.0979 |
0.854 |
| 2.4 |
0.591 |
251.00 |
0.542 |
0.175 |
0.1980 |
0.886 |
| 2.5 |
0.520 |
316.00 |
0.542 |
0.197 |
0.1550 |
0.929 |
| 2.6 |
0.456 |
398.00 |
0.542 |
0.201 |
0.1480 |
0.936 |
| 2.7 |
0.375 |
501.00 |
0.542 |
0.224 |
0.1040 |
0.981 |
| 2.8 |
0.293 |
631.00 |
0.587 |
0.232 |
0.1320 |
1.040 |
IgG_A244D11K169
Monotone

| 0.0 |
1.000 |
1.00 |
0.00361 |
0.000724 |
0.002190 |
0.00503 |
| 0.1 |
0.994 |
1.26 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.2 |
0.994 |
1.58 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.3 |
0.994 |
2.00 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.4 |
0.994 |
2.51 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.5 |
0.994 |
3.16 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.6 |
0.994 |
3.98 |
0.00349 |
0.000758 |
0.002000 |
0.00497 |
| 0.7 |
0.992 |
5.01 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 0.8 |
0.992 |
6.31 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 0.9 |
0.992 |
7.94 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 1.0 |
0.992 |
10.00 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 1.1 |
0.992 |
12.60 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 1.2 |
0.992 |
15.80 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 1.3 |
0.992 |
20.00 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 1.4 |
0.991 |
25.10 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.5 |
0.991 |
31.60 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.6 |
0.989 |
39.80 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.7 |
0.989 |
50.10 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.8 |
0.988 |
63.10 |
0.00349 |
0.000761 |
0.002000 |
0.00498 |
| 1.9 |
0.988 |
79.40 |
0.00349 |
0.000761 |
0.002000 |
0.00498 |
| 2.0 |
0.986 |
100.00 |
0.00349 |
0.000763 |
0.001990 |
0.00498 |
| 2.1 |
0.986 |
126.00 |
0.00349 |
0.000763 |
0.001990 |
0.00498 |
| 2.2 |
0.985 |
158.00 |
0.00349 |
0.000764 |
0.001990 |
0.00499 |
| 2.3 |
0.985 |
200.00 |
0.00349 |
0.000764 |
0.001990 |
0.00499 |
| 2.4 |
0.985 |
251.00 |
0.00349 |
0.000764 |
0.001990 |
0.00499 |
| 2.5 |
0.985 |
316.00 |
0.00349 |
0.000764 |
0.001990 |
0.00499 |
| 2.6 |
0.985 |
398.00 |
0.00349 |
0.000764 |
0.001990 |
0.00499 |
| 2.7 |
0.984 |
501.00 |
0.00346 |
0.000746 |
0.002000 |
0.00492 |
| 2.8 |
0.970 |
631.00 |
0.00346 |
0.000757 |
0.001980 |
0.00494 |
| 2.9 |
0.959 |
794.00 |
0.00346 |
0.000763 |
0.001960 |
0.00495 |
| 3.0 |
0.947 |
1000.00 |
0.00346 |
0.000772 |
0.001950 |
0.00497 |
| 3.1 |
0.912 |
1260.00 |
0.00346 |
0.000784 |
0.001920 |
0.00500 |
| 3.2 |
0.860 |
1580.00 |
0.00346 |
0.000810 |
0.001870 |
0.00505 |
| 3.3 |
0.804 |
2000.00 |
0.00346 |
0.000823 |
0.001850 |
0.00507 |
| 3.4 |
0.706 |
2510.00 |
0.00346 |
0.000862 |
0.001770 |
0.00515 |
| 3.5 |
0.582 |
3160.00 |
0.00346 |
0.001100 |
0.001300 |
0.00562 |
| 3.6 |
0.428 |
3980.00 |
0.00346 |
0.001240 |
0.001020 |
0.00590 |
| 3.7 |
0.385 |
5010.00 |
0.00346 |
0.001200 |
0.001110 |
0.00581 |
| 3.8 |
0.272 |
6310.00 |
0.00346 |
0.001340 |
0.000831 |
0.00609 |
| 3.9 |
0.149 |
7940.00 |
0.00346 |
0.002320 |
-0.001090 |
0.00801 |
| 4.0 |
0.085 |
10000.00 |
0.00346 |
0.003790 |
-0.003980 |
0.01090 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.994 |
0.00348 |
0.000758 |
0.001990 |
0.00497 |
| 0.2 |
1.58 |
0.994 |
0.00348 |
0.000758 |
0.001990 |
0.00497 |
| 0.3 |
2.00 |
0.994 |
0.00348 |
0.000758 |
0.001990 |
0.00497 |
| 0.4 |
2.51 |
0.994 |
0.00348 |
0.000758 |
0.001990 |
0.00497 |
| 0.5 |
3.16 |
0.994 |
0.00348 |
0.000758 |
0.001990 |
0.00497 |
| 0.6 |
3.98 |
0.994 |
0.00348 |
0.000758 |
0.001990 |
0.00497 |
| 0.7 |
5.01 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 0.8 |
6.31 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 0.9 |
7.94 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 1.0 |
10.00 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 1.1 |
12.60 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 1.2 |
15.80 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 1.3 |
20.00 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 1.4 |
25.10 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.5 |
31.60 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.6 |
39.80 |
0.989 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.7 |
50.10 |
0.989 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.8 |
63.10 |
0.988 |
0.00349 |
0.000761 |
0.002000 |
0.00498 |
| 1.9 |
79.40 |
0.988 |
0.00349 |
0.000761 |
0.002000 |
0.00498 |
| 2.0 |
100.00 |
0.986 |
0.00350 |
0.000763 |
0.002010 |
0.00500 |
| 2.1 |
126.00 |
0.986 |
0.00350 |
0.000763 |
0.002010 |
0.00500 |
| 2.2 |
158.00 |
0.985 |
0.00350 |
0.000764 |
0.002010 |
0.00500 |
| 2.3 |
200.00 |
0.985 |
0.00350 |
0.000764 |
0.002010 |
0.00500 |
| 2.4 |
251.00 |
0.985 |
0.00350 |
0.000764 |
0.002010 |
0.00500 |
| 2.5 |
316.00 |
0.985 |
0.00350 |
0.000764 |
0.002010 |
0.00500 |
| 2.6 |
398.00 |
0.985 |
0.00350 |
0.000764 |
0.002010 |
0.00500 |
| 2.7 |
501.00 |
0.984 |
0.00336 |
0.000746 |
0.001900 |
0.00482 |
| 2.8 |
631.00 |
0.970 |
0.00341 |
0.000757 |
0.001930 |
0.00490 |
| 2.9 |
794.00 |
0.959 |
0.00344 |
0.000763 |
0.001940 |
0.00494 |
| 3.0 |
1000.00 |
0.947 |
0.00348 |
0.000772 |
0.001970 |
0.00499 |
| 3.1 |
1260.00 |
0.912 |
0.00346 |
0.000784 |
0.001920 |
0.00499 |
| 3.2 |
1580.00 |
0.860 |
0.00348 |
0.000810 |
0.001890 |
0.00507 |
| 3.3 |
2000.00 |
0.804 |
0.00337 |
0.000823 |
0.001750 |
0.00498 |
| 3.4 |
2510.00 |
0.706 |
0.00322 |
0.000862 |
0.001530 |
0.00491 |
| 3.5 |
3160.00 |
0.582 |
0.00370 |
0.001100 |
0.001540 |
0.00587 |
| 3.6 |
3980.00 |
0.428 |
0.00379 |
0.001240 |
0.001360 |
0.00623 |
| 3.7 |
5010.00 |
0.385 |
0.00330 |
0.001200 |
0.000953 |
0.00566 |
| 3.8 |
6310.00 |
0.272 |
0.00328 |
0.001340 |
0.000656 |
0.00591 |
| 3.9 |
7940.00 |
0.149 |
0.00511 |
0.002320 |
0.000562 |
0.00966 |
| 4.0 |
10000.00 |
0.085 |
0.00562 |
0.003790 |
-0.001820 |
0.01310 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.220 |
0.214 |
-0.199 |
0.638 |
| 0.1 |
0.994 |
1.26 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 0.2 |
0.994 |
1.58 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 0.3 |
0.994 |
2.00 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 0.4 |
0.994 |
2.51 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 0.5 |
0.994 |
3.16 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 0.6 |
0.994 |
3.98 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 0.7 |
0.992 |
5.01 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 0.8 |
0.992 |
6.31 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 0.9 |
0.992 |
7.94 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 1.0 |
0.992 |
10.00 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 1.1 |
0.992 |
12.60 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 1.2 |
0.992 |
15.80 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 1.3 |
0.992 |
20.00 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 1.4 |
0.991 |
25.10 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 1.5 |
0.991 |
31.60 |
0.246 |
0.216 |
-0.177 |
0.669 |
| 1.6 |
0.989 |
39.80 |
0.246 |
0.216 |
-0.178 |
0.670 |
| 1.7 |
0.989 |
50.10 |
0.246 |
0.216 |
-0.178 |
0.670 |
| 1.8 |
0.988 |
63.10 |
0.246 |
0.216 |
-0.178 |
0.670 |
| 1.9 |
0.988 |
79.40 |
0.246 |
0.216 |
-0.178 |
0.670 |
| 2.0 |
0.986 |
100.00 |
0.246 |
0.217 |
-0.178 |
0.670 |
| 2.1 |
0.986 |
126.00 |
0.246 |
0.217 |
-0.178 |
0.670 |
| 2.2 |
0.985 |
158.00 |
0.246 |
0.217 |
-0.179 |
0.671 |
| 2.3 |
0.985 |
200.00 |
0.246 |
0.217 |
-0.179 |
0.671 |
| 2.4 |
0.985 |
251.00 |
0.246 |
0.217 |
-0.179 |
0.671 |
| 2.5 |
0.985 |
316.00 |
0.246 |
0.217 |
-0.179 |
0.671 |
| 2.6 |
0.985 |
398.00 |
0.246 |
0.217 |
-0.179 |
0.671 |
| 2.7 |
0.984 |
501.00 |
0.252 |
0.213 |
-0.165 |
0.670 |
| 2.8 |
0.970 |
631.00 |
0.252 |
0.215 |
-0.168 |
0.673 |
| 2.9 |
0.959 |
794.00 |
0.252 |
0.216 |
-0.171 |
0.675 |
| 3.0 |
0.947 |
1000.00 |
0.252 |
0.217 |
-0.173 |
0.678 |
| 3.1 |
0.912 |
1260.00 |
0.252 |
0.219 |
-0.177 |
0.682 |
| 3.2 |
0.860 |
1580.00 |
0.252 |
0.224 |
-0.186 |
0.691 |
| 3.3 |
0.804 |
2000.00 |
0.252 |
0.226 |
-0.190 |
0.695 |
| 3.4 |
0.706 |
2510.00 |
0.252 |
0.233 |
-0.203 |
0.708 |
| 3.5 |
0.582 |
3160.00 |
0.252 |
0.276 |
-0.288 |
0.793 |
| 3.6 |
0.428 |
3980.00 |
0.252 |
0.303 |
-0.340 |
0.845 |
| 3.7 |
0.385 |
5010.00 |
0.252 |
0.294 |
-0.324 |
0.829 |
| 3.8 |
0.272 |
6310.00 |
0.252 |
0.321 |
-0.378 |
0.883 |
| 3.9 |
0.149 |
7940.00 |
0.252 |
0.520 |
-0.767 |
1.270 |
| 4.0 |
0.085 |
10000.00 |
0.252 |
0.832 |
-1.380 |
1.880 |
IgG_gp70ClAEV1V2
Monotone

| 0.0 |
1.000 |
1.00 |
0.00362 |
0.000724 |
0.00220 |
0.00504 |
| 0.1 |
0.997 |
1.26 |
0.00362 |
0.000774 |
0.00211 |
0.00514 |
| 0.2 |
0.997 |
1.58 |
0.00362 |
0.000774 |
0.00211 |
0.00514 |
| 0.3 |
0.997 |
2.00 |
0.00362 |
0.000774 |
0.00211 |
0.00514 |
| 0.4 |
0.995 |
2.51 |
0.00362 |
0.000775 |
0.00210 |
0.00514 |
| 0.5 |
0.994 |
3.16 |
0.00362 |
0.000776 |
0.00210 |
0.00514 |
| 0.6 |
0.992 |
3.98 |
0.00362 |
0.000776 |
0.00210 |
0.00514 |
| 0.7 |
0.992 |
5.01 |
0.00362 |
0.000776 |
0.00210 |
0.00514 |
| 0.8 |
0.992 |
6.31 |
0.00362 |
0.000776 |
0.00210 |
0.00514 |
| 0.9 |
0.992 |
7.94 |
0.00362 |
0.000776 |
0.00210 |
0.00514 |
| 1.0 |
0.992 |
10.00 |
0.00362 |
0.000776 |
0.00210 |
0.00514 |
| 1.1 |
0.992 |
12.60 |
0.00362 |
0.000776 |
0.00210 |
0.00514 |
| 1.2 |
0.992 |
15.80 |
0.00362 |
0.000776 |
0.00210 |
0.00514 |
| 1.3 |
0.992 |
20.00 |
0.00349 |
0.000759 |
0.00200 |
0.00498 |
| 1.4 |
0.992 |
25.10 |
0.00349 |
0.000759 |
0.00200 |
0.00498 |
| 1.5 |
0.992 |
31.60 |
0.00349 |
0.000759 |
0.00200 |
0.00498 |
| 1.6 |
0.992 |
39.80 |
0.00349 |
0.000759 |
0.00200 |
0.00498 |
| 1.7 |
0.991 |
50.10 |
0.00349 |
0.000760 |
0.00200 |
0.00498 |
| 1.8 |
0.991 |
63.10 |
0.00349 |
0.000760 |
0.00200 |
0.00498 |
| 1.9 |
0.991 |
79.40 |
0.00349 |
0.000760 |
0.00200 |
0.00498 |
| 2.0 |
0.991 |
100.00 |
0.00349 |
0.000760 |
0.00200 |
0.00498 |
| 2.1 |
0.991 |
126.00 |
0.00349 |
0.000760 |
0.00200 |
0.00498 |
| 2.2 |
0.991 |
158.00 |
0.00349 |
0.000760 |
0.00200 |
0.00498 |
| 2.3 |
0.991 |
200.00 |
0.00349 |
0.000760 |
0.00200 |
0.00498 |
| 2.4 |
0.989 |
251.00 |
0.00349 |
0.000761 |
0.00200 |
0.00498 |
| 2.5 |
0.988 |
316.00 |
0.00349 |
0.000762 |
0.00200 |
0.00498 |
| 2.6 |
0.986 |
398.00 |
0.00349 |
0.000763 |
0.00200 |
0.00499 |
| 2.7 |
0.986 |
501.00 |
0.00349 |
0.000763 |
0.00200 |
0.00499 |
| 2.8 |
0.986 |
631.00 |
0.00349 |
0.000763 |
0.00200 |
0.00499 |
| 2.9 |
0.981 |
794.00 |
0.00349 |
0.000765 |
0.00199 |
0.00499 |
| 3.0 |
0.981 |
1000.00 |
0.00349 |
0.000765 |
0.00199 |
0.00499 |
| 3.1 |
0.981 |
1260.00 |
0.00342 |
0.000748 |
0.00196 |
0.00489 |
| 3.2 |
0.977 |
1580.00 |
0.00342 |
0.000753 |
0.00195 |
0.00490 |
| 3.3 |
0.972 |
2000.00 |
0.00342 |
0.000755 |
0.00194 |
0.00490 |
| 3.4 |
0.960 |
2510.00 |
0.00342 |
0.000766 |
0.00192 |
0.00493 |
| 3.5 |
0.960 |
3160.00 |
0.00342 |
0.000766 |
0.00192 |
0.00493 |
| 3.6 |
0.956 |
3980.00 |
0.00342 |
0.000769 |
0.00192 |
0.00493 |
| 3.7 |
0.956 |
5010.00 |
0.00318 |
0.000732 |
0.00174 |
0.00461 |
| 3.8 |
0.945 |
6310.00 |
0.00318 |
0.000738 |
0.00173 |
0.00463 |
| 3.9 |
0.923 |
7940.00 |
0.00300 |
0.000718 |
0.00159 |
0.00441 |
| 4.0 |
0.914 |
10000.00 |
0.00300 |
0.000724 |
0.00158 |
0.00442 |
| 4.1 |
0.868 |
12600.00 |
0.00300 |
0.000748 |
0.00154 |
0.00447 |
| 4.2 |
0.807 |
15800.00 |
0.00300 |
0.000788 |
0.00146 |
0.00455 |
| 4.3 |
0.729 |
20000.00 |
0.00294 |
0.000805 |
0.00136 |
0.00452 |
| 4.4 |
0.401 |
25100.00 |
0.00294 |
0.001230 |
0.00054 |
0.00534 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.00210 |
0.00513 |
| 0.1 |
1.26 |
0.997 |
0.00362 |
0.000774 |
0.00210 |
0.00514 |
| 0.2 |
1.58 |
0.997 |
0.00362 |
0.000774 |
0.00210 |
0.00514 |
| 0.3 |
2.00 |
0.997 |
0.00362 |
0.000774 |
0.00210 |
0.00514 |
| 0.4 |
2.51 |
0.995 |
0.00362 |
0.000775 |
0.00210 |
0.00514 |
| 0.5 |
3.16 |
0.994 |
0.00362 |
0.000776 |
0.00210 |
0.00514 |
| 0.6 |
3.98 |
0.992 |
0.00363 |
0.000776 |
0.00211 |
0.00515 |
| 0.7 |
5.01 |
0.992 |
0.00363 |
0.000776 |
0.00211 |
0.00515 |
| 0.8 |
6.31 |
0.992 |
0.00363 |
0.000776 |
0.00211 |
0.00515 |
| 0.9 |
7.94 |
0.992 |
0.00363 |
0.000776 |
0.00211 |
0.00515 |
| 1.0 |
10.00 |
0.992 |
0.00363 |
0.000776 |
0.00211 |
0.00515 |
| 1.1 |
12.60 |
0.992 |
0.00363 |
0.000776 |
0.00211 |
0.00515 |
| 1.2 |
15.80 |
0.992 |
0.00363 |
0.000776 |
0.00211 |
0.00515 |
| 1.3 |
20.00 |
0.992 |
0.00348 |
0.000759 |
0.00199 |
0.00497 |
| 1.4 |
25.10 |
0.992 |
0.00348 |
0.000759 |
0.00199 |
0.00497 |
| 1.5 |
31.60 |
0.992 |
0.00348 |
0.000759 |
0.00199 |
0.00497 |
| 1.6 |
39.80 |
0.992 |
0.00348 |
0.000759 |
0.00199 |
0.00497 |
| 1.7 |
50.10 |
0.991 |
0.00348 |
0.000760 |
0.00200 |
0.00497 |
| 1.8 |
63.10 |
0.991 |
0.00348 |
0.000760 |
0.00200 |
0.00497 |
| 1.9 |
79.40 |
0.991 |
0.00348 |
0.000760 |
0.00200 |
0.00497 |
| 2.0 |
100.00 |
0.991 |
0.00348 |
0.000760 |
0.00200 |
0.00497 |
| 2.1 |
126.00 |
0.991 |
0.00348 |
0.000760 |
0.00200 |
0.00497 |
| 2.2 |
158.00 |
0.991 |
0.00348 |
0.000760 |
0.00200 |
0.00497 |
| 2.3 |
200.00 |
0.991 |
0.00348 |
0.000760 |
0.00200 |
0.00497 |
| 2.4 |
251.00 |
0.989 |
0.00349 |
0.000761 |
0.00200 |
0.00499 |
| 2.5 |
316.00 |
0.988 |
0.00350 |
0.000762 |
0.00200 |
0.00499 |
| 2.6 |
398.00 |
0.986 |
0.00350 |
0.000763 |
0.00201 |
0.00500 |
| 2.7 |
501.00 |
0.986 |
0.00350 |
0.000763 |
0.00201 |
0.00500 |
| 2.8 |
631.00 |
0.986 |
0.00350 |
0.000763 |
0.00201 |
0.00500 |
| 2.9 |
794.00 |
0.981 |
0.00351 |
0.000765 |
0.00201 |
0.00501 |
| 3.0 |
1000.00 |
0.981 |
0.00351 |
0.000765 |
0.00201 |
0.00501 |
| 3.1 |
1260.00 |
0.981 |
0.00337 |
0.000748 |
0.00190 |
0.00483 |
| 3.2 |
1580.00 |
0.977 |
0.00339 |
0.000753 |
0.00192 |
0.00487 |
| 3.3 |
2000.00 |
0.972 |
0.00341 |
0.000755 |
0.00193 |
0.00489 |
| 3.4 |
2510.00 |
0.960 |
0.00345 |
0.000766 |
0.00195 |
0.00496 |
| 3.5 |
3160.00 |
0.960 |
0.00345 |
0.000766 |
0.00195 |
0.00496 |
| 3.6 |
3980.00 |
0.956 |
0.00347 |
0.000769 |
0.00196 |
0.00497 |
| 3.7 |
5010.00 |
0.956 |
0.00317 |
0.000732 |
0.00173 |
0.00460 |
| 3.8 |
6310.00 |
0.945 |
0.00319 |
0.000738 |
0.00175 |
0.00464 |
| 3.9 |
7940.00 |
0.923 |
0.00296 |
0.000718 |
0.00156 |
0.00437 |
| 4.0 |
10000.00 |
0.914 |
0.00298 |
0.000724 |
0.00157 |
0.00440 |
| 4.1 |
12600.00 |
0.868 |
0.00300 |
0.000748 |
0.00153 |
0.00446 |
| 4.2 |
15800.00 |
0.807 |
0.00306 |
0.000788 |
0.00152 |
0.00461 |
| 4.3 |
20000.00 |
0.729 |
0.00294 |
0.000805 |
0.00136 |
0.00452 |
| 4.4 |
25100.00 |
0.401 |
0.00345 |
0.001230 |
0.00105 |
0.00585 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.217 |
0.214 |
-0.2020 |
0.636 |
| 0.1 |
0.997 |
1.26 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.2 |
0.997 |
1.58 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.3 |
0.997 |
2.00 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.4 |
0.995 |
2.51 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.5 |
0.994 |
3.16 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.6 |
0.992 |
3.98 |
0.217 |
0.222 |
-0.2190 |
0.653 |
| 0.7 |
0.992 |
5.01 |
0.217 |
0.222 |
-0.2190 |
0.653 |
| 0.8 |
0.992 |
6.31 |
0.217 |
0.222 |
-0.2190 |
0.653 |
| 0.9 |
0.992 |
7.94 |
0.217 |
0.222 |
-0.2190 |
0.653 |
| 1.0 |
0.992 |
10.00 |
0.217 |
0.222 |
-0.2190 |
0.653 |
| 1.1 |
0.992 |
12.60 |
0.217 |
0.222 |
-0.2190 |
0.653 |
| 1.2 |
0.992 |
15.80 |
0.217 |
0.222 |
-0.2190 |
0.653 |
| 1.3 |
0.992 |
20.00 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.4 |
0.992 |
25.10 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.5 |
0.992 |
31.60 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.6 |
0.992 |
39.80 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.7 |
0.991 |
50.10 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.8 |
0.991 |
63.10 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 1.9 |
0.991 |
79.40 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 2.0 |
0.991 |
100.00 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 2.1 |
0.991 |
126.00 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 2.2 |
0.991 |
158.00 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 2.3 |
0.991 |
200.00 |
0.246 |
0.216 |
-0.1780 |
0.669 |
| 2.4 |
0.989 |
251.00 |
0.246 |
0.216 |
-0.1780 |
0.670 |
| 2.5 |
0.988 |
316.00 |
0.246 |
0.216 |
-0.1790 |
0.670 |
| 2.6 |
0.986 |
398.00 |
0.246 |
0.217 |
-0.1790 |
0.670 |
| 2.7 |
0.986 |
501.00 |
0.246 |
0.217 |
-0.1790 |
0.670 |
| 2.8 |
0.986 |
631.00 |
0.246 |
0.217 |
-0.1790 |
0.670 |
| 2.9 |
0.981 |
794.00 |
0.246 |
0.217 |
-0.1800 |
0.671 |
| 3.0 |
0.981 |
1000.00 |
0.246 |
0.217 |
-0.1800 |
0.671 |
| 3.1 |
0.981 |
1260.00 |
0.260 |
0.212 |
-0.1560 |
0.676 |
| 3.2 |
0.977 |
1580.00 |
0.260 |
0.213 |
-0.1580 |
0.678 |
| 3.3 |
0.972 |
2000.00 |
0.260 |
0.214 |
-0.1590 |
0.679 |
| 3.4 |
0.960 |
2510.00 |
0.260 |
0.215 |
-0.1620 |
0.682 |
| 3.5 |
0.960 |
3160.00 |
0.260 |
0.215 |
-0.1620 |
0.682 |
| 3.6 |
0.956 |
3980.00 |
0.260 |
0.216 |
-0.1630 |
0.683 |
| 3.7 |
0.956 |
5010.00 |
0.313 |
0.203 |
-0.0857 |
0.712 |
| 3.8 |
0.945 |
6310.00 |
0.313 |
0.205 |
-0.0879 |
0.714 |
| 3.9 |
0.923 |
7940.00 |
0.351 |
0.197 |
-0.0340 |
0.737 |
| 4.0 |
0.914 |
10000.00 |
0.351 |
0.198 |
-0.0360 |
0.739 |
| 4.1 |
0.868 |
12600.00 |
0.351 |
0.202 |
-0.0440 |
0.747 |
| 4.2 |
0.807 |
15800.00 |
0.351 |
0.209 |
-0.0579 |
0.761 |
| 4.3 |
0.729 |
20000.00 |
0.364 |
0.210 |
-0.0482 |
0.777 |
| 4.4 |
0.401 |
25100.00 |
0.364 |
0.290 |
-0.2050 |
0.933 |
IgG_gp70V1V2A
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00361 |
0.000724 |
2.19e-03 |
0.00503 |
| 0.1 |
0.9920 |
1.26 |
0.00352 |
0.000759 |
2.03e-03 |
0.00501 |
| 0.2 |
0.9920 |
1.58 |
0.00352 |
0.000759 |
2.03e-03 |
0.00501 |
| 0.3 |
0.9920 |
2.00 |
0.00352 |
0.000759 |
2.03e-03 |
0.00501 |
| 0.4 |
0.9910 |
2.51 |
0.00352 |
0.000761 |
2.03e-03 |
0.00501 |
| 0.5 |
0.9890 |
3.16 |
0.00352 |
0.000761 |
2.03e-03 |
0.00501 |
| 0.6 |
0.9890 |
3.98 |
0.00352 |
0.000761 |
2.03e-03 |
0.00501 |
| 0.7 |
0.9880 |
5.01 |
0.00352 |
0.000762 |
2.02e-03 |
0.00501 |
| 0.8 |
0.9860 |
6.31 |
0.00352 |
0.000763 |
2.02e-03 |
0.00501 |
| 0.9 |
0.9820 |
7.94 |
0.00352 |
0.000765 |
2.02e-03 |
0.00502 |
| 1.0 |
0.9820 |
10.00 |
0.00352 |
0.000765 |
2.02e-03 |
0.00502 |
| 1.1 |
0.9820 |
12.60 |
0.00352 |
0.000765 |
2.02e-03 |
0.00502 |
| 1.2 |
0.9680 |
15.80 |
0.00352 |
0.000775 |
2.00e-03 |
0.00504 |
| 1.3 |
0.9680 |
20.00 |
0.00352 |
0.000775 |
2.00e-03 |
0.00504 |
| 1.4 |
0.9680 |
25.10 |
0.00352 |
0.000775 |
2.00e-03 |
0.00504 |
| 1.5 |
0.9680 |
31.60 |
0.00352 |
0.000775 |
2.00e-03 |
0.00504 |
| 1.6 |
0.9530 |
39.80 |
0.00347 |
0.000767 |
1.97e-03 |
0.00498 |
| 1.7 |
0.9480 |
50.10 |
0.00347 |
0.000774 |
1.96e-03 |
0.00499 |
| 1.8 |
0.9420 |
63.10 |
0.00338 |
0.000760 |
1.89e-03 |
0.00487 |
| 1.9 |
0.9290 |
79.40 |
0.00338 |
0.000772 |
1.87e-03 |
0.00489 |
| 2.0 |
0.9000 |
100.00 |
0.00332 |
0.000769 |
1.81e-03 |
0.00482 |
| 2.1 |
0.8790 |
126.00 |
0.00323 |
0.000768 |
1.73e-03 |
0.00474 |
| 2.2 |
0.8520 |
158.00 |
0.00286 |
0.000732 |
1.42e-03 |
0.00429 |
| 2.3 |
0.8390 |
200.00 |
0.00254 |
0.000689 |
1.19e-03 |
0.00389 |
| 2.4 |
0.8080 |
251.00 |
0.00246 |
0.000691 |
1.11e-03 |
0.00382 |
| 2.5 |
0.7580 |
316.00 |
0.00206 |
0.000648 |
7.92e-04 |
0.00333 |
| 2.6 |
0.7120 |
398.00 |
0.00206 |
0.000629 |
8.28e-04 |
0.00329 |
| 2.7 |
0.6310 |
501.00 |
0.00206 |
0.000675 |
7.37e-04 |
0.00338 |
| 2.8 |
0.5160 |
631.00 |
0.00206 |
0.000755 |
5.80e-04 |
0.00354 |
| 2.9 |
0.4650 |
794.00 |
0.00206 |
0.000850 |
3.95e-04 |
0.00373 |
| 3.0 |
0.4290 |
1000.00 |
0.00206 |
0.000831 |
4.31e-04 |
0.00369 |
| 3.1 |
0.3440 |
1260.00 |
0.00206 |
0.000961 |
1.76e-04 |
0.00395 |
| 3.2 |
0.2870 |
1580.00 |
0.00206 |
0.001100 |
-8.71e-05 |
0.00421 |
| 3.3 |
0.2160 |
2000.00 |
0.00206 |
0.001380 |
-6.51e-04 |
0.00477 |
| 3.4 |
0.1630 |
2510.00 |
0.00206 |
0.001870 |
-1.60e-03 |
0.00572 |
| 3.5 |
0.1300 |
3160.00 |
0.00206 |
0.002510 |
-2.86e-03 |
0.00698 |
| 3.6 |
0.0981 |
3980.00 |
0.00206 |
0.003960 |
-5.70e-03 |
0.00982 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.9920 |
0.00348 |
0.000759 |
0.002000 |
0.00497 |
| 0.2 |
1.58 |
0.9920 |
0.00348 |
0.000759 |
0.002000 |
0.00497 |
| 0.3 |
2.00 |
0.9920 |
0.00348 |
0.000759 |
0.002000 |
0.00497 |
| 0.4 |
2.51 |
0.9910 |
0.00349 |
0.000761 |
0.002000 |
0.00498 |
| 0.5 |
3.16 |
0.9890 |
0.00350 |
0.000761 |
0.002000 |
0.00499 |
| 0.6 |
3.98 |
0.9890 |
0.00350 |
0.000761 |
0.002000 |
0.00499 |
| 0.7 |
5.01 |
0.9880 |
0.00350 |
0.000762 |
0.002010 |
0.00499 |
| 0.8 |
6.31 |
0.9860 |
0.00350 |
0.000763 |
0.002010 |
0.00500 |
| 0.9 |
7.94 |
0.9820 |
0.00352 |
0.000765 |
0.002020 |
0.00502 |
| 1.0 |
10.00 |
0.9820 |
0.00352 |
0.000765 |
0.002020 |
0.00502 |
| 1.1 |
12.60 |
0.9820 |
0.00352 |
0.000765 |
0.002020 |
0.00502 |
| 1.2 |
15.80 |
0.9680 |
0.00357 |
0.000775 |
0.002050 |
0.00509 |
| 1.3 |
20.00 |
0.9680 |
0.00357 |
0.000775 |
0.002050 |
0.00509 |
| 1.4 |
25.10 |
0.9680 |
0.00357 |
0.000775 |
0.002050 |
0.00509 |
| 1.5 |
31.60 |
0.9680 |
0.00357 |
0.000775 |
0.002050 |
0.00509 |
| 1.6 |
39.80 |
0.9530 |
0.00346 |
0.000767 |
0.001960 |
0.00496 |
| 1.7 |
50.10 |
0.9480 |
0.00349 |
0.000774 |
0.001970 |
0.00500 |
| 1.8 |
63.10 |
0.9420 |
0.00336 |
0.000760 |
0.001870 |
0.00484 |
| 1.9 |
79.40 |
0.9290 |
0.00341 |
0.000772 |
0.001890 |
0.00492 |
| 2.0 |
100.00 |
0.9000 |
0.00332 |
0.000769 |
0.001810 |
0.00482 |
| 2.1 |
126.00 |
0.8790 |
0.00323 |
0.000768 |
0.001730 |
0.00474 |
| 2.2 |
158.00 |
0.8520 |
0.00286 |
0.000732 |
0.001420 |
0.00429 |
| 2.3 |
200.00 |
0.8390 |
0.00254 |
0.000689 |
0.001190 |
0.00389 |
| 2.4 |
251.00 |
0.8080 |
0.00246 |
0.000691 |
0.001110 |
0.00382 |
| 2.5 |
316.00 |
0.7580 |
0.00205 |
0.000648 |
0.000785 |
0.00332 |
| 2.6 |
398.00 |
0.7120 |
0.00181 |
0.000629 |
0.000579 |
0.00305 |
| 2.7 |
501.00 |
0.6310 |
0.00182 |
0.000675 |
0.000502 |
0.00315 |
| 2.8 |
631.00 |
0.5160 |
0.00189 |
0.000755 |
0.000405 |
0.00337 |
| 2.9 |
794.00 |
0.4650 |
0.00212 |
0.000850 |
0.000454 |
0.00378 |
| 3.0 |
1000.00 |
0.4290 |
0.00190 |
0.000831 |
0.000275 |
0.00353 |
| 3.1 |
1260.00 |
0.3440 |
0.00175 |
0.000961 |
-0.000134 |
0.00363 |
| 3.2 |
1580.00 |
0.2870 |
0.00201 |
0.001100 |
-0.000142 |
0.00415 |
| 3.3 |
2000.00 |
0.2160 |
0.00259 |
0.001380 |
-0.000121 |
0.00530 |
| 3.4 |
2510.00 |
0.1630 |
0.00349 |
0.001870 |
-0.000174 |
0.00715 |
| 3.5 |
3160.00 |
0.1300 |
0.00463 |
0.002510 |
-0.000286 |
0.00955 |
| 3.6 |
3980.00 |
0.0981 |
0.00694 |
0.003960 |
-0.000818 |
0.01470 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.220 |
0.214 |
-0.199000 |
0.638 |
| 0.1 |
0.9920 |
1.26 |
0.240 |
0.217 |
-0.185000 |
0.664 |
| 0.2 |
0.9920 |
1.58 |
0.240 |
0.217 |
-0.185000 |
0.664 |
| 0.3 |
0.9920 |
2.00 |
0.240 |
0.217 |
-0.185000 |
0.664 |
| 0.4 |
0.9910 |
2.51 |
0.240 |
0.217 |
-0.185000 |
0.665 |
| 0.5 |
0.9890 |
3.16 |
0.240 |
0.217 |
-0.186000 |
0.665 |
| 0.6 |
0.9890 |
3.98 |
0.240 |
0.217 |
-0.186000 |
0.665 |
| 0.7 |
0.9880 |
5.01 |
0.240 |
0.217 |
-0.186000 |
0.666 |
| 0.8 |
0.9860 |
6.31 |
0.240 |
0.217 |
-0.186000 |
0.666 |
| 0.9 |
0.9820 |
7.94 |
0.240 |
0.218 |
-0.187000 |
0.666 |
| 1.0 |
0.9820 |
10.00 |
0.240 |
0.218 |
-0.187000 |
0.666 |
| 1.1 |
0.9820 |
12.60 |
0.240 |
0.218 |
-0.187000 |
0.666 |
| 1.2 |
0.9680 |
15.80 |
0.240 |
0.219 |
-0.190000 |
0.670 |
| 1.3 |
0.9680 |
20.00 |
0.240 |
0.219 |
-0.190000 |
0.670 |
| 1.4 |
0.9680 |
25.10 |
0.240 |
0.219 |
-0.190000 |
0.670 |
| 1.5 |
0.9680 |
31.60 |
0.240 |
0.219 |
-0.190000 |
0.670 |
| 1.6 |
0.9530 |
39.80 |
0.250 |
0.217 |
-0.175000 |
0.675 |
| 1.7 |
0.9480 |
50.10 |
0.250 |
0.218 |
-0.178000 |
0.677 |
| 1.8 |
0.9420 |
63.10 |
0.269 |
0.213 |
-0.149000 |
0.687 |
| 1.9 |
0.9290 |
79.40 |
0.269 |
0.215 |
-0.153000 |
0.691 |
| 2.0 |
0.9000 |
100.00 |
0.283 |
0.213 |
-0.135000 |
0.701 |
| 2.1 |
0.8790 |
126.00 |
0.301 |
0.211 |
-0.112000 |
0.714 |
| 2.2 |
0.8520 |
158.00 |
0.383 |
0.195 |
-0.000602 |
0.766 |
| 2.3 |
0.8390 |
200.00 |
0.451 |
0.181 |
0.097600 |
0.805 |
| 2.4 |
0.8080 |
251.00 |
0.468 |
0.179 |
0.117000 |
0.819 |
| 2.5 |
0.7580 |
316.00 |
0.555 |
0.163 |
0.236000 |
0.873 |
| 2.6 |
0.7120 |
398.00 |
0.555 |
0.159 |
0.243000 |
0.867 |
| 2.7 |
0.6310 |
501.00 |
0.555 |
0.168 |
0.226000 |
0.884 |
| 2.8 |
0.5160 |
631.00 |
0.555 |
0.183 |
0.196000 |
0.914 |
| 2.9 |
0.4650 |
794.00 |
0.555 |
0.202 |
0.160000 |
0.950 |
| 3.0 |
0.4290 |
1000.00 |
0.555 |
0.198 |
0.167000 |
0.943 |
| 3.1 |
0.3440 |
1260.00 |
0.555 |
0.224 |
0.116000 |
0.993 |
| 3.2 |
0.2870 |
1580.00 |
0.555 |
0.251 |
0.062900 |
1.050 |
| 3.3 |
0.2160 |
2000.00 |
0.555 |
0.310 |
-0.053400 |
1.160 |
| 3.4 |
0.1630 |
2510.00 |
0.555 |
0.412 |
-0.253000 |
1.360 |
| 3.5 |
0.1300 |
3160.00 |
0.555 |
0.549 |
-0.521000 |
1.630 |
| 3.6 |
0.0981 |
3980.00 |
0.555 |
0.859 |
-1.130000 |
2.240 |
IgG_gp70V1V2AP
Monotone

| 0.0 |
1.000 |
1.00 |
0.00361 |
0.000724 |
0.002190 |
0.00503 |
| 0.1 |
0.998 |
1.26 |
0.00348 |
0.000756 |
0.002000 |
0.00497 |
| 0.2 |
0.998 |
1.58 |
0.00348 |
0.000756 |
0.002000 |
0.00497 |
| 0.3 |
0.998 |
2.00 |
0.00348 |
0.000756 |
0.002000 |
0.00497 |
| 0.4 |
0.997 |
2.51 |
0.00348 |
0.000757 |
0.002000 |
0.00497 |
| 0.5 |
0.997 |
3.16 |
0.00348 |
0.000757 |
0.002000 |
0.00497 |
| 0.6 |
0.992 |
3.98 |
0.00348 |
0.000759 |
0.002000 |
0.00497 |
| 0.7 |
0.987 |
5.01 |
0.00348 |
0.000762 |
0.001990 |
0.00498 |
| 0.8 |
0.982 |
6.31 |
0.00348 |
0.000765 |
0.001980 |
0.00498 |
| 0.9 |
0.974 |
7.94 |
0.00342 |
0.000753 |
0.001940 |
0.00490 |
| 1.0 |
0.974 |
10.00 |
0.00342 |
0.000753 |
0.001940 |
0.00490 |
| 1.1 |
0.974 |
12.60 |
0.00342 |
0.000753 |
0.001940 |
0.00490 |
| 1.2 |
0.974 |
15.80 |
0.00342 |
0.000753 |
0.001940 |
0.00490 |
| 1.3 |
0.958 |
20.00 |
0.00342 |
0.000767 |
0.001920 |
0.00492 |
| 1.4 |
0.950 |
25.10 |
0.00342 |
0.000773 |
0.001900 |
0.00493 |
| 1.5 |
0.950 |
31.60 |
0.00334 |
0.000754 |
0.001860 |
0.00482 |
| 1.6 |
0.940 |
39.80 |
0.00334 |
0.000759 |
0.001850 |
0.00483 |
| 1.7 |
0.919 |
50.10 |
0.00312 |
0.000734 |
0.001680 |
0.00456 |
| 1.8 |
0.908 |
63.10 |
0.00312 |
0.000743 |
0.001660 |
0.00457 |
| 1.9 |
0.885 |
79.40 |
0.00294 |
0.000720 |
0.001530 |
0.00435 |
| 2.0 |
0.844 |
100.00 |
0.00294 |
0.000748 |
0.001480 |
0.00441 |
| 2.1 |
0.792 |
126.00 |
0.00271 |
0.000739 |
0.001270 |
0.00416 |
| 2.2 |
0.735 |
158.00 |
0.00258 |
0.000726 |
0.001150 |
0.00400 |
| 2.3 |
0.652 |
200.00 |
0.00258 |
0.000789 |
0.001030 |
0.00412 |
| 2.4 |
0.606 |
251.00 |
0.00258 |
0.000811 |
0.000986 |
0.00417 |
| 2.5 |
0.524 |
316.00 |
0.00258 |
0.000902 |
0.000808 |
0.00435 |
| 2.6 |
0.460 |
398.00 |
0.00258 |
0.001030 |
0.000558 |
0.00459 |
| 2.7 |
0.398 |
501.00 |
0.00258 |
0.001190 |
0.000241 |
0.00491 |
| 2.8 |
0.341 |
631.00 |
0.00258 |
0.001130 |
0.000366 |
0.00479 |
| 2.9 |
0.258 |
794.00 |
0.00258 |
0.001230 |
0.000166 |
0.00499 |
| 3.0 |
0.207 |
1000.00 |
0.00258 |
0.001660 |
-0.000673 |
0.00583 |
| 3.1 |
0.175 |
1260.00 |
0.00258 |
0.001250 |
0.000119 |
0.00503 |
| 3.2 |
0.124 |
1580.00 |
0.00258 |
0.002010 |
-0.001360 |
0.00651 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.998 |
0.00347 |
0.000756 |
0.001990 |
0.00495 |
| 0.2 |
1.58 |
0.998 |
0.00347 |
0.000756 |
0.001990 |
0.00495 |
| 0.3 |
2.00 |
0.998 |
0.00347 |
0.000756 |
0.001990 |
0.00495 |
| 0.4 |
2.51 |
0.997 |
0.00347 |
0.000757 |
0.001990 |
0.00496 |
| 0.5 |
3.16 |
0.997 |
0.00347 |
0.000757 |
0.001990 |
0.00496 |
| 0.6 |
3.98 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 0.7 |
5.01 |
0.987 |
0.00350 |
0.000762 |
0.002010 |
0.00500 |
| 0.8 |
6.31 |
0.982 |
0.00352 |
0.000765 |
0.002020 |
0.00501 |
| 0.9 |
7.94 |
0.974 |
0.00339 |
0.000753 |
0.001920 |
0.00487 |
| 1.0 |
10.00 |
0.974 |
0.00339 |
0.000753 |
0.001920 |
0.00487 |
| 1.1 |
12.60 |
0.974 |
0.00339 |
0.000753 |
0.001920 |
0.00487 |
| 1.2 |
15.80 |
0.974 |
0.00339 |
0.000753 |
0.001920 |
0.00487 |
| 1.3 |
20.00 |
0.958 |
0.00346 |
0.000767 |
0.001960 |
0.00496 |
| 1.4 |
25.10 |
0.950 |
0.00348 |
0.000773 |
0.001970 |
0.00500 |
| 1.5 |
31.60 |
0.950 |
0.00333 |
0.000754 |
0.001850 |
0.00481 |
| 1.6 |
39.80 |
0.940 |
0.00335 |
0.000759 |
0.001860 |
0.00484 |
| 1.7 |
50.10 |
0.919 |
0.00310 |
0.000734 |
0.001660 |
0.00454 |
| 1.8 |
63.10 |
0.908 |
0.00313 |
0.000743 |
0.001680 |
0.00459 |
| 1.9 |
79.40 |
0.885 |
0.00289 |
0.000720 |
0.001480 |
0.00430 |
| 2.0 |
100.00 |
0.844 |
0.00300 |
0.000748 |
0.001530 |
0.00446 |
| 2.1 |
126.00 |
0.792 |
0.00271 |
0.000739 |
0.001270 |
0.00416 |
| 2.2 |
158.00 |
0.735 |
0.00249 |
0.000726 |
0.001060 |
0.00391 |
| 2.3 |
200.00 |
0.652 |
0.00259 |
0.000789 |
0.001050 |
0.00414 |
| 2.4 |
251.00 |
0.606 |
0.00255 |
0.000811 |
0.000963 |
0.00414 |
| 2.5 |
316.00 |
0.524 |
0.00269 |
0.000902 |
0.000921 |
0.00446 |
| 2.6 |
398.00 |
0.460 |
0.00290 |
0.001030 |
0.000886 |
0.00492 |
| 2.7 |
501.00 |
0.398 |
0.00333 |
0.001190 |
0.000996 |
0.00567 |
| 2.8 |
631.00 |
0.341 |
0.00278 |
0.001130 |
0.000568 |
0.00499 |
| 2.9 |
794.00 |
0.258 |
0.00227 |
0.001230 |
-0.000137 |
0.00468 |
| 3.0 |
1000.00 |
0.207 |
0.00296 |
0.001660 |
-0.000289 |
0.00621 |
| 3.1 |
1260.00 |
0.175 |
0.00207 |
0.001250 |
-0.000392 |
0.00452 |
| 3.2 |
1580.00 |
0.124 |
0.00325 |
0.002010 |
-0.000692 |
0.00718 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.220 |
0.214 |
-0.1990 |
0.638 |
| 0.1 |
0.998 |
1.26 |
0.247 |
0.215 |
-0.1750 |
0.669 |
| 0.2 |
0.998 |
1.58 |
0.247 |
0.215 |
-0.1750 |
0.669 |
| 0.3 |
0.998 |
2.00 |
0.247 |
0.215 |
-0.1750 |
0.669 |
| 0.4 |
0.997 |
2.51 |
0.247 |
0.215 |
-0.1750 |
0.670 |
| 0.5 |
0.997 |
3.16 |
0.247 |
0.215 |
-0.1750 |
0.670 |
| 0.6 |
0.992 |
3.98 |
0.247 |
0.216 |
-0.1750 |
0.670 |
| 0.7 |
0.987 |
5.01 |
0.247 |
0.216 |
-0.1770 |
0.671 |
| 0.8 |
0.982 |
6.31 |
0.247 |
0.217 |
-0.1770 |
0.672 |
| 0.9 |
0.974 |
7.94 |
0.261 |
0.213 |
-0.1570 |
0.679 |
| 1.0 |
0.974 |
10.00 |
0.261 |
0.213 |
-0.1570 |
0.679 |
| 1.1 |
0.974 |
12.60 |
0.261 |
0.213 |
-0.1570 |
0.679 |
| 1.2 |
0.974 |
15.80 |
0.261 |
0.213 |
-0.1570 |
0.679 |
| 1.3 |
0.958 |
20.00 |
0.261 |
0.215 |
-0.1610 |
0.683 |
| 1.4 |
0.950 |
25.10 |
0.261 |
0.216 |
-0.1630 |
0.685 |
| 1.5 |
0.950 |
31.60 |
0.278 |
0.211 |
-0.1360 |
0.692 |
| 1.6 |
0.940 |
39.80 |
0.278 |
0.212 |
-0.1380 |
0.694 |
| 1.7 |
0.919 |
50.10 |
0.326 |
0.202 |
-0.0700 |
0.723 |
| 1.8 |
0.908 |
63.10 |
0.326 |
0.204 |
-0.0729 |
0.726 |
| 1.9 |
0.885 |
79.40 |
0.364 |
0.196 |
-0.0191 |
0.747 |
| 2.0 |
0.844 |
100.00 |
0.364 |
0.200 |
-0.0286 |
0.757 |
| 2.1 |
0.792 |
126.00 |
0.414 |
0.193 |
0.0345 |
0.793 |
| 2.2 |
0.735 |
158.00 |
0.443 |
0.188 |
0.0747 |
0.812 |
| 2.3 |
0.652 |
200.00 |
0.443 |
0.200 |
0.0521 |
0.834 |
| 2.4 |
0.606 |
251.00 |
0.443 |
0.204 |
0.0440 |
0.842 |
| 2.5 |
0.524 |
316.00 |
0.443 |
0.221 |
0.0104 |
0.876 |
| 2.6 |
0.460 |
398.00 |
0.443 |
0.245 |
-0.0379 |
0.924 |
| 2.7 |
0.398 |
501.00 |
0.443 |
0.278 |
-0.1010 |
0.987 |
| 2.8 |
0.341 |
631.00 |
0.443 |
0.265 |
-0.0759 |
0.962 |
| 2.9 |
0.258 |
794.00 |
0.443 |
0.285 |
-0.1160 |
1.000 |
| 3.0 |
0.207 |
1000.00 |
0.443 |
0.373 |
-0.2880 |
1.170 |
| 3.1 |
0.175 |
1260.00 |
0.443 |
0.290 |
-0.1250 |
1.010 |
| 3.2 |
0.124 |
1580.00 |
0.443 |
0.446 |
-0.4320 |
1.320 |
IgG_gp70V1V2C
Monotone

| 0.0 |
1.000 |
1.00 |
0.00361 |
0.000724 |
2.19e-03 |
0.00503 |
| 0.1 |
0.988 |
1.26 |
0.00354 |
0.000766 |
2.03e-03 |
0.00504 |
| 0.2 |
0.988 |
1.58 |
0.00354 |
0.000766 |
2.03e-03 |
0.00504 |
| 0.3 |
0.988 |
2.00 |
0.00354 |
0.000766 |
2.03e-03 |
0.00504 |
| 0.4 |
0.987 |
2.51 |
0.00354 |
0.000767 |
2.03e-03 |
0.00504 |
| 0.5 |
0.985 |
3.16 |
0.00354 |
0.000767 |
2.03e-03 |
0.00504 |
| 0.6 |
0.985 |
3.98 |
0.00354 |
0.000767 |
2.03e-03 |
0.00504 |
| 0.7 |
0.984 |
5.01 |
0.00354 |
0.000770 |
2.03e-03 |
0.00505 |
| 0.8 |
0.984 |
6.31 |
0.00354 |
0.000770 |
2.03e-03 |
0.00505 |
| 0.9 |
0.978 |
7.94 |
0.00354 |
0.000771 |
2.02e-03 |
0.00505 |
| 1.0 |
0.969 |
10.00 |
0.00354 |
0.000778 |
2.01e-03 |
0.00506 |
| 1.1 |
0.962 |
12.60 |
0.00354 |
0.000783 |
2.00e-03 |
0.00507 |
| 1.2 |
0.956 |
15.80 |
0.00349 |
0.000768 |
1.98e-03 |
0.00499 |
| 1.3 |
0.946 |
20.00 |
0.00349 |
0.000779 |
1.96e-03 |
0.00501 |
| 1.4 |
0.936 |
25.10 |
0.00323 |
0.000748 |
1.76e-03 |
0.00470 |
| 1.5 |
0.927 |
31.60 |
0.00298 |
0.000716 |
1.58e-03 |
0.00438 |
| 1.6 |
0.915 |
39.80 |
0.00298 |
0.000722 |
1.57e-03 |
0.00440 |
| 1.7 |
0.899 |
50.10 |
0.00298 |
0.000731 |
1.55e-03 |
0.00441 |
| 1.8 |
0.881 |
63.10 |
0.00276 |
0.000706 |
1.38e-03 |
0.00415 |
| 1.9 |
0.852 |
79.40 |
0.00266 |
0.000700 |
1.29e-03 |
0.00403 |
| 2.0 |
0.830 |
100.00 |
0.00260 |
0.000693 |
1.24e-03 |
0.00395 |
| 2.1 |
0.796 |
126.00 |
0.00260 |
0.000721 |
1.18e-03 |
0.00401 |
| 2.2 |
0.738 |
158.00 |
0.00244 |
0.000715 |
1.04e-03 |
0.00384 |
| 2.3 |
0.678 |
200.00 |
0.00243 |
0.000743 |
9.80e-04 |
0.00389 |
| 2.4 |
0.624 |
251.00 |
0.00243 |
0.000812 |
8.43e-04 |
0.00403 |
| 2.5 |
0.575 |
316.00 |
0.00192 |
0.000707 |
5.29e-04 |
0.00330 |
| 2.6 |
0.533 |
398.00 |
0.00179 |
0.000704 |
4.12e-04 |
0.00317 |
| 2.7 |
0.449 |
501.00 |
0.00179 |
0.000739 |
3.42e-04 |
0.00324 |
| 2.8 |
0.378 |
631.00 |
0.00179 |
0.000877 |
7.32e-05 |
0.00351 |
| 2.9 |
0.304 |
794.00 |
0.00179 |
0.000966 |
-1.02e-04 |
0.00368 |
| 3.0 |
0.252 |
1000.00 |
0.00179 |
0.001130 |
-4.22e-04 |
0.00400 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
2.10e-03 |
0.00513 |
| 0.1 |
1.26 |
0.988 |
0.00352 |
0.000766 |
2.01e-03 |
0.00502 |
| 0.2 |
1.58 |
0.988 |
0.00352 |
0.000766 |
2.01e-03 |
0.00502 |
| 0.3 |
2.00 |
0.988 |
0.00352 |
0.000766 |
2.01e-03 |
0.00502 |
| 0.4 |
2.51 |
0.987 |
0.00352 |
0.000767 |
2.02e-03 |
0.00502 |
| 0.5 |
3.16 |
0.985 |
0.00352 |
0.000767 |
2.02e-03 |
0.00503 |
| 0.6 |
3.98 |
0.985 |
0.00352 |
0.000767 |
2.02e-03 |
0.00503 |
| 0.7 |
5.01 |
0.984 |
0.00353 |
0.000770 |
2.02e-03 |
0.00504 |
| 0.8 |
6.31 |
0.984 |
0.00353 |
0.000770 |
2.02e-03 |
0.00504 |
| 0.9 |
7.94 |
0.978 |
0.00355 |
0.000771 |
2.04e-03 |
0.00506 |
| 1.0 |
10.00 |
0.969 |
0.00358 |
0.000778 |
2.05e-03 |
0.00510 |
| 1.1 |
12.60 |
0.962 |
0.00360 |
0.000783 |
2.06e-03 |
0.00513 |
| 1.2 |
15.80 |
0.956 |
0.00346 |
0.000768 |
1.96e-03 |
0.00497 |
| 1.3 |
20.00 |
0.946 |
0.00351 |
0.000779 |
1.98e-03 |
0.00504 |
| 1.4 |
25.10 |
0.936 |
0.00323 |
0.000748 |
1.76e-03 |
0.00470 |
| 1.5 |
31.60 |
0.927 |
0.00295 |
0.000716 |
1.55e-03 |
0.00436 |
| 1.6 |
39.80 |
0.915 |
0.00298 |
0.000722 |
1.56e-03 |
0.00439 |
| 1.7 |
50.10 |
0.899 |
0.00301 |
0.000731 |
1.58e-03 |
0.00444 |
| 1.8 |
63.10 |
0.881 |
0.00276 |
0.000706 |
1.38e-03 |
0.00415 |
| 1.9 |
79.40 |
0.852 |
0.00266 |
0.000700 |
1.29e-03 |
0.00403 |
| 2.0 |
100.00 |
0.830 |
0.00255 |
0.000693 |
1.19e-03 |
0.00391 |
| 2.1 |
126.00 |
0.796 |
0.00264 |
0.000721 |
1.23e-03 |
0.00406 |
| 2.2 |
158.00 |
0.738 |
0.00244 |
0.000715 |
1.04e-03 |
0.00384 |
| 2.3 |
200.00 |
0.678 |
0.00233 |
0.000743 |
8.74e-04 |
0.00378 |
| 2.4 |
251.00 |
0.624 |
0.00254 |
0.000812 |
9.53e-04 |
0.00414 |
| 2.5 |
316.00 |
0.575 |
0.00192 |
0.000707 |
5.29e-04 |
0.00330 |
| 2.6 |
398.00 |
0.533 |
0.00178 |
0.000704 |
4.04e-04 |
0.00316 |
| 2.7 |
501.00 |
0.449 |
0.00159 |
0.000739 |
1.43e-04 |
0.00304 |
| 2.8 |
631.00 |
0.378 |
0.00187 |
0.000877 |
1.57e-04 |
0.00359 |
| 2.9 |
794.00 |
0.304 |
0.00183 |
0.000966 |
-6.63e-05 |
0.00372 |
| 3.0 |
1000.00 |
0.252 |
0.00188 |
0.001130 |
-3.34e-04 |
0.00409 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.220 |
0.214 |
-0.1990 |
0.638 |
| 0.1 |
0.988 |
1.26 |
0.236 |
0.218 |
-0.1920 |
0.664 |
| 0.2 |
0.988 |
1.58 |
0.236 |
0.218 |
-0.1920 |
0.664 |
| 0.3 |
0.988 |
2.00 |
0.236 |
0.218 |
-0.1920 |
0.664 |
| 0.4 |
0.987 |
2.51 |
0.236 |
0.218 |
-0.1920 |
0.664 |
| 0.5 |
0.985 |
3.16 |
0.236 |
0.219 |
-0.1920 |
0.664 |
| 0.6 |
0.985 |
3.98 |
0.236 |
0.219 |
-0.1920 |
0.664 |
| 0.7 |
0.984 |
5.01 |
0.236 |
0.219 |
-0.1930 |
0.665 |
| 0.8 |
0.984 |
6.31 |
0.236 |
0.219 |
-0.1930 |
0.665 |
| 0.9 |
0.978 |
7.94 |
0.236 |
0.219 |
-0.1940 |
0.665 |
| 1.0 |
0.969 |
10.00 |
0.236 |
0.220 |
-0.1960 |
0.667 |
| 1.1 |
0.962 |
12.60 |
0.236 |
0.221 |
-0.1970 |
0.669 |
| 1.2 |
0.956 |
15.80 |
0.247 |
0.217 |
-0.1790 |
0.673 |
| 1.3 |
0.946 |
20.00 |
0.247 |
0.219 |
-0.1830 |
0.676 |
| 1.4 |
0.936 |
25.10 |
0.302 |
0.207 |
-0.1040 |
0.708 |
| 1.5 |
0.927 |
31.60 |
0.356 |
0.196 |
-0.0278 |
0.740 |
| 1.6 |
0.915 |
39.80 |
0.356 |
0.197 |
-0.0299 |
0.742 |
| 1.7 |
0.899 |
50.10 |
0.356 |
0.198 |
-0.0328 |
0.745 |
| 1.8 |
0.881 |
63.10 |
0.403 |
0.189 |
0.0333 |
0.773 |
| 1.9 |
0.852 |
79.40 |
0.426 |
0.185 |
0.0623 |
0.789 |
| 2.0 |
0.830 |
100.00 |
0.439 |
0.183 |
0.0813 |
0.797 |
| 2.1 |
0.796 |
126.00 |
0.439 |
0.188 |
0.0715 |
0.807 |
| 2.2 |
0.738 |
158.00 |
0.473 |
0.183 |
0.1140 |
0.832 |
| 2.3 |
0.678 |
200.00 |
0.474 |
0.188 |
0.1050 |
0.842 |
| 2.4 |
0.624 |
251.00 |
0.474 |
0.201 |
0.0799 |
0.868 |
| 2.5 |
0.575 |
316.00 |
0.586 |
0.171 |
0.2510 |
0.922 |
| 2.6 |
0.533 |
398.00 |
0.613 |
0.168 |
0.2830 |
0.943 |
| 2.7 |
0.449 |
501.00 |
0.613 |
0.175 |
0.2690 |
0.956 |
| 2.8 |
0.378 |
631.00 |
0.613 |
0.203 |
0.2160 |
1.010 |
| 2.9 |
0.304 |
794.00 |
0.613 |
0.221 |
0.1800 |
1.050 |
| 3.0 |
0.252 |
1000.00 |
0.613 |
0.254 |
0.1140 |
1.110 |
IgG_gp70BCaseA2V1V2169K
Monotone

| 0.0 |
1.000 |
1.00 |
0.00361 |
0.000724 |
2.19e-03 |
0.00503 |
| 0.1 |
0.998 |
1.26 |
0.00349 |
0.000756 |
2.00e-03 |
0.00497 |
| 0.2 |
0.998 |
1.58 |
0.00349 |
0.000756 |
2.00e-03 |
0.00497 |
| 0.3 |
0.998 |
2.00 |
0.00349 |
0.000756 |
2.00e-03 |
0.00497 |
| 0.4 |
0.997 |
2.51 |
0.00349 |
0.000757 |
2.00e-03 |
0.00497 |
| 0.5 |
0.995 |
3.16 |
0.00349 |
0.000758 |
2.00e-03 |
0.00497 |
| 0.6 |
0.995 |
3.98 |
0.00349 |
0.000758 |
2.00e-03 |
0.00497 |
| 0.7 |
0.994 |
5.01 |
0.00349 |
0.000758 |
2.00e-03 |
0.00497 |
| 0.8 |
0.994 |
6.31 |
0.00349 |
0.000758 |
2.00e-03 |
0.00497 |
| 0.9 |
0.991 |
7.94 |
0.00349 |
0.000760 |
2.00e-03 |
0.00497 |
| 1.0 |
0.989 |
10.00 |
0.00349 |
0.000760 |
1.99e-03 |
0.00498 |
| 1.1 |
0.989 |
12.60 |
0.00349 |
0.000760 |
1.99e-03 |
0.00498 |
| 1.2 |
0.989 |
15.80 |
0.00349 |
0.000760 |
1.99e-03 |
0.00498 |
| 1.3 |
0.982 |
20.00 |
0.00349 |
0.000766 |
1.98e-03 |
0.00499 |
| 1.4 |
0.975 |
25.10 |
0.00349 |
0.000769 |
1.98e-03 |
0.00499 |
| 1.5 |
0.971 |
31.60 |
0.00342 |
0.000755 |
1.94e-03 |
0.00489 |
| 1.6 |
0.967 |
39.80 |
0.00342 |
0.000758 |
1.93e-03 |
0.00490 |
| 1.7 |
0.961 |
50.10 |
0.00342 |
0.000763 |
1.92e-03 |
0.00491 |
| 1.8 |
0.957 |
63.10 |
0.00330 |
0.000747 |
1.83e-03 |
0.00476 |
| 1.9 |
0.941 |
79.40 |
0.00321 |
0.000742 |
1.75e-03 |
0.00466 |
| 2.0 |
0.941 |
100.00 |
0.00305 |
0.000722 |
1.64e-03 |
0.00447 |
| 2.1 |
0.937 |
126.00 |
0.00292 |
0.000708 |
1.53e-03 |
0.00431 |
| 2.2 |
0.920 |
158.00 |
0.00282 |
0.000701 |
1.44e-03 |
0.00419 |
| 2.3 |
0.885 |
200.00 |
0.00276 |
0.000699 |
1.39e-03 |
0.00413 |
| 2.4 |
0.864 |
251.00 |
0.00276 |
0.000716 |
1.36e-03 |
0.00417 |
| 2.5 |
0.827 |
316.00 |
0.00256 |
0.000696 |
1.19e-03 |
0.00392 |
| 2.6 |
0.781 |
398.00 |
0.00254 |
0.000717 |
1.13e-03 |
0.00394 |
| 2.7 |
0.723 |
501.00 |
0.00235 |
0.000715 |
9.51e-04 |
0.00375 |
| 2.8 |
0.675 |
631.00 |
0.00217 |
0.000683 |
8.27e-04 |
0.00350 |
| 2.9 |
0.615 |
794.00 |
0.00217 |
0.000758 |
6.79e-04 |
0.00365 |
| 3.0 |
0.539 |
1000.00 |
0.00217 |
0.000822 |
5.55e-04 |
0.00378 |
| 3.1 |
0.501 |
1260.00 |
0.00217 |
0.000869 |
4.62e-04 |
0.00387 |
| 3.2 |
0.399 |
1580.00 |
0.00217 |
0.001110 |
-1.56e-05 |
0.00435 |
| 3.3 |
0.337 |
2000.00 |
0.00217 |
0.001260 |
-3.13e-04 |
0.00464 |
| 3.4 |
0.263 |
2510.00 |
0.00217 |
0.001400 |
-5.70e-04 |
0.00490 |
| 3.5 |
0.207 |
3160.00 |
0.00217 |
0.001990 |
-1.74e-03 |
0.00607 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
2.10e-03 |
0.00513 |
| 0.1 |
1.26 |
0.998 |
0.00347 |
0.000756 |
1.99e-03 |
0.00495 |
| 0.2 |
1.58 |
0.998 |
0.00347 |
0.000756 |
1.99e-03 |
0.00495 |
| 0.3 |
2.00 |
0.998 |
0.00347 |
0.000756 |
1.99e-03 |
0.00495 |
| 0.4 |
2.51 |
0.997 |
0.00347 |
0.000757 |
1.99e-03 |
0.00496 |
| 0.5 |
3.16 |
0.995 |
0.00348 |
0.000758 |
1.99e-03 |
0.00496 |
| 0.6 |
3.98 |
0.995 |
0.00348 |
0.000758 |
1.99e-03 |
0.00496 |
| 0.7 |
5.01 |
0.994 |
0.00348 |
0.000758 |
1.99e-03 |
0.00497 |
| 0.8 |
6.31 |
0.994 |
0.00348 |
0.000758 |
1.99e-03 |
0.00497 |
| 0.9 |
7.94 |
0.991 |
0.00348 |
0.000760 |
2.00e-03 |
0.00497 |
| 1.0 |
10.00 |
0.989 |
0.00349 |
0.000760 |
2.00e-03 |
0.00498 |
| 1.1 |
12.60 |
0.989 |
0.00349 |
0.000760 |
2.00e-03 |
0.00498 |
| 1.2 |
15.80 |
0.989 |
0.00349 |
0.000760 |
2.00e-03 |
0.00498 |
| 1.3 |
20.00 |
0.982 |
0.00351 |
0.000766 |
2.01e-03 |
0.00501 |
| 1.4 |
25.10 |
0.975 |
0.00352 |
0.000769 |
2.02e-03 |
0.00503 |
| 1.5 |
31.60 |
0.971 |
0.00340 |
0.000755 |
1.92e-03 |
0.00488 |
| 1.6 |
39.80 |
0.967 |
0.00341 |
0.000758 |
1.93e-03 |
0.00490 |
| 1.7 |
50.10 |
0.961 |
0.00344 |
0.000763 |
1.94e-03 |
0.00493 |
| 1.8 |
63.10 |
0.957 |
0.00330 |
0.000747 |
1.83e-03 |
0.00476 |
| 1.9 |
79.40 |
0.941 |
0.00321 |
0.000742 |
1.75e-03 |
0.00466 |
| 2.0 |
100.00 |
0.941 |
0.00305 |
0.000722 |
1.64e-03 |
0.00447 |
| 2.1 |
126.00 |
0.937 |
0.00292 |
0.000708 |
1.53e-03 |
0.00431 |
| 2.2 |
158.00 |
0.920 |
0.00282 |
0.000701 |
1.44e-03 |
0.00419 |
| 2.3 |
200.00 |
0.885 |
0.00273 |
0.000699 |
1.36e-03 |
0.00410 |
| 2.4 |
251.00 |
0.864 |
0.00280 |
0.000716 |
1.39e-03 |
0.00420 |
| 2.5 |
316.00 |
0.827 |
0.00256 |
0.000696 |
1.19e-03 |
0.00392 |
| 2.6 |
398.00 |
0.781 |
0.00254 |
0.000717 |
1.13e-03 |
0.00394 |
| 2.7 |
501.00 |
0.723 |
0.00235 |
0.000715 |
9.51e-04 |
0.00375 |
| 2.8 |
631.00 |
0.675 |
0.00206 |
0.000683 |
7.17e-04 |
0.00339 |
| 2.9 |
794.00 |
0.615 |
0.00228 |
0.000758 |
7.91e-04 |
0.00376 |
| 3.0 |
1000.00 |
0.539 |
0.00233 |
0.000822 |
7.20e-04 |
0.00394 |
| 3.1 |
1260.00 |
0.501 |
0.00231 |
0.000869 |
6.06e-04 |
0.00401 |
| 3.2 |
1580.00 |
0.399 |
0.00268 |
0.001110 |
5.03e-04 |
0.00486 |
| 3.3 |
2000.00 |
0.337 |
0.00275 |
0.001260 |
2.71e-04 |
0.00523 |
| 3.4 |
2510.00 |
0.263 |
0.00281 |
0.001400 |
7.51e-05 |
0.00554 |
| 3.5 |
3160.00 |
0.207 |
0.00350 |
0.001990 |
-4.06e-04 |
0.00741 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.220 |
0.214 |
-0.19900 |
0.638 |
| 0.1 |
0.998 |
1.26 |
0.247 |
0.215 |
-0.17500 |
0.669 |
| 0.2 |
0.998 |
1.58 |
0.247 |
0.215 |
-0.17500 |
0.669 |
| 0.3 |
0.998 |
2.00 |
0.247 |
0.215 |
-0.17500 |
0.669 |
| 0.4 |
0.997 |
2.51 |
0.247 |
0.215 |
-0.17500 |
0.669 |
| 0.5 |
0.995 |
3.16 |
0.247 |
0.216 |
-0.17600 |
0.669 |
| 0.6 |
0.995 |
3.98 |
0.247 |
0.216 |
-0.17600 |
0.669 |
| 0.7 |
0.994 |
5.01 |
0.247 |
0.216 |
-0.17600 |
0.670 |
| 0.8 |
0.994 |
6.31 |
0.247 |
0.216 |
-0.17600 |
0.670 |
| 0.9 |
0.991 |
7.94 |
0.247 |
0.216 |
-0.17600 |
0.670 |
| 1.0 |
0.989 |
10.00 |
0.247 |
0.216 |
-0.17700 |
0.670 |
| 1.1 |
0.989 |
12.60 |
0.247 |
0.216 |
-0.17700 |
0.670 |
| 1.2 |
0.989 |
15.80 |
0.247 |
0.216 |
-0.17700 |
0.670 |
| 1.3 |
0.982 |
20.00 |
0.247 |
0.217 |
-0.17800 |
0.672 |
| 1.4 |
0.975 |
25.10 |
0.247 |
0.217 |
-0.17900 |
0.673 |
| 1.5 |
0.971 |
31.60 |
0.262 |
0.213 |
-0.15600 |
0.680 |
| 1.6 |
0.967 |
39.80 |
0.262 |
0.214 |
-0.15700 |
0.681 |
| 1.7 |
0.961 |
50.10 |
0.262 |
0.215 |
-0.15900 |
0.683 |
| 1.8 |
0.957 |
63.10 |
0.287 |
0.209 |
-0.12200 |
0.697 |
| 1.9 |
0.941 |
79.40 |
0.307 |
0.206 |
-0.09610 |
0.711 |
| 2.0 |
0.941 |
100.00 |
0.341 |
0.199 |
-0.04860 |
0.730 |
| 2.1 |
0.937 |
126.00 |
0.369 |
0.193 |
-0.00972 |
0.747 |
| 2.2 |
0.920 |
158.00 |
0.391 |
0.189 |
0.02070 |
0.762 |
| 2.3 |
0.885 |
200.00 |
0.403 |
0.188 |
0.03480 |
0.770 |
| 2.4 |
0.864 |
251.00 |
0.403 |
0.191 |
0.02910 |
0.776 |
| 2.5 |
0.827 |
316.00 |
0.448 |
0.182 |
0.09080 |
0.805 |
| 2.6 |
0.781 |
398.00 |
0.452 |
0.186 |
0.08820 |
0.816 |
| 2.7 |
0.723 |
501.00 |
0.492 |
0.181 |
0.13600 |
0.847 |
| 2.8 |
0.675 |
631.00 |
0.532 |
0.171 |
0.19600 |
0.868 |
| 2.9 |
0.615 |
794.00 |
0.532 |
0.186 |
0.16800 |
0.896 |
| 3.0 |
0.539 |
1000.00 |
0.532 |
0.198 |
0.14400 |
0.920 |
| 3.1 |
0.501 |
1260.00 |
0.532 |
0.207 |
0.12600 |
0.938 |
| 3.2 |
0.399 |
1580.00 |
0.532 |
0.256 |
0.03090 |
1.030 |
| 3.3 |
0.337 |
2000.00 |
0.532 |
0.287 |
-0.03010 |
1.090 |
| 3.4 |
0.263 |
2510.00 |
0.532 |
0.314 |
-0.08310 |
1.150 |
| 3.5 |
0.207 |
3160.00 |
0.532 |
0.440 |
-0.33000 |
1.390 |
IgG_gp70BCaseA2V1V2mut3
Monotone

| 0.0 |
1.000 |
1.00 |
0.00362 |
0.000724 |
0.002200 |
0.00504 |
| 0.1 |
0.997 |
1.26 |
0.00362 |
0.000774 |
0.002100 |
0.00514 |
| 0.2 |
0.997 |
1.58 |
0.00362 |
0.000774 |
0.002100 |
0.00514 |
| 0.3 |
0.997 |
2.00 |
0.00362 |
0.000774 |
0.002100 |
0.00514 |
| 0.4 |
0.997 |
2.51 |
0.00362 |
0.000774 |
0.002100 |
0.00514 |
| 0.5 |
0.997 |
3.16 |
0.00362 |
0.000774 |
0.002100 |
0.00514 |
| 0.6 |
0.995 |
3.98 |
0.00362 |
0.000775 |
0.002100 |
0.00514 |
| 0.7 |
0.994 |
5.01 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 0.8 |
0.994 |
6.31 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 0.9 |
0.992 |
7.94 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 1.0 |
0.992 |
10.00 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 1.1 |
0.992 |
12.60 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 1.2 |
0.992 |
15.80 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 1.3 |
0.992 |
20.00 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 1.4 |
0.992 |
25.10 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 1.5 |
0.992 |
31.60 |
0.00349 |
0.000759 |
0.002000 |
0.00498 |
| 1.6 |
0.991 |
39.80 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.7 |
0.991 |
50.10 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.8 |
0.991 |
63.10 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 1.9 |
0.991 |
79.40 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 2.0 |
0.991 |
100.00 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 2.1 |
0.991 |
126.00 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 2.2 |
0.991 |
158.00 |
0.00349 |
0.000760 |
0.002000 |
0.00498 |
| 2.3 |
0.989 |
200.00 |
0.00349 |
0.000761 |
0.002000 |
0.00498 |
| 2.4 |
0.986 |
251.00 |
0.00349 |
0.000763 |
0.002000 |
0.00499 |
| 2.5 |
0.986 |
316.00 |
0.00349 |
0.000763 |
0.002000 |
0.00499 |
| 2.6 |
0.986 |
398.00 |
0.00349 |
0.000763 |
0.002000 |
0.00499 |
| 2.7 |
0.986 |
501.00 |
0.00349 |
0.000763 |
0.002000 |
0.00499 |
| 2.8 |
0.981 |
631.00 |
0.00349 |
0.000765 |
0.001990 |
0.00499 |
| 2.9 |
0.981 |
794.00 |
0.00349 |
0.000765 |
0.001990 |
0.00499 |
| 3.0 |
0.981 |
1000.00 |
0.00342 |
0.000748 |
0.001950 |
0.00488 |
| 3.1 |
0.977 |
1260.00 |
0.00342 |
0.000753 |
0.001940 |
0.00489 |
| 3.2 |
0.972 |
1580.00 |
0.00342 |
0.000755 |
0.001940 |
0.00490 |
| 3.3 |
0.960 |
2000.00 |
0.00342 |
0.000766 |
0.001920 |
0.00492 |
| 3.4 |
0.956 |
2510.00 |
0.00342 |
0.000769 |
0.001910 |
0.00492 |
| 3.5 |
0.956 |
3160.00 |
0.00331 |
0.000750 |
0.001840 |
0.00478 |
| 3.6 |
0.950 |
3980.00 |
0.00318 |
0.000735 |
0.001740 |
0.00462 |
| 3.7 |
0.931 |
5010.00 |
0.00300 |
0.000711 |
0.001600 |
0.00439 |
| 3.8 |
0.914 |
6310.00 |
0.00300 |
0.000723 |
0.001580 |
0.00441 |
| 3.9 |
0.905 |
7940.00 |
0.00300 |
0.000733 |
0.001560 |
0.00443 |
| 4.0 |
0.829 |
10000.00 |
0.00300 |
0.000761 |
0.001500 |
0.00449 |
| 4.1 |
0.751 |
12600.00 |
0.00300 |
0.000817 |
0.001390 |
0.00460 |
| 4.2 |
0.683 |
15800.00 |
0.00298 |
0.000813 |
0.001390 |
0.00457 |
| 4.3 |
0.558 |
20000.00 |
0.00298 |
0.000986 |
0.001050 |
0.00491 |
| 4.4 |
0.314 |
25100.00 |
0.00298 |
0.001620 |
-0.000189 |
0.00615 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.997 |
0.00362 |
0.000774 |
0.002100 |
0.00514 |
| 0.2 |
1.58 |
0.997 |
0.00362 |
0.000774 |
0.002100 |
0.00514 |
| 0.3 |
2.00 |
0.997 |
0.00362 |
0.000774 |
0.002100 |
0.00514 |
| 0.4 |
2.51 |
0.997 |
0.00362 |
0.000774 |
0.002100 |
0.00514 |
| 0.5 |
3.16 |
0.997 |
0.00362 |
0.000774 |
0.002100 |
0.00514 |
| 0.6 |
3.98 |
0.995 |
0.00362 |
0.000775 |
0.002100 |
0.00514 |
| 0.7 |
5.01 |
0.994 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 0.8 |
6.31 |
0.994 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 0.9 |
7.94 |
0.992 |
0.00363 |
0.000776 |
0.002110 |
0.00515 |
| 1.0 |
10.00 |
0.992 |
0.00363 |
0.000776 |
0.002110 |
0.00515 |
| 1.1 |
12.60 |
0.992 |
0.00363 |
0.000776 |
0.002110 |
0.00515 |
| 1.2 |
15.80 |
0.992 |
0.00363 |
0.000776 |
0.002110 |
0.00515 |
| 1.3 |
20.00 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 1.4 |
25.10 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 1.5 |
31.60 |
0.992 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 1.6 |
39.80 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.7 |
50.10 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.8 |
63.10 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 1.9 |
79.40 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 2.0 |
100.00 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 2.1 |
126.00 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 2.2 |
158.00 |
0.991 |
0.00348 |
0.000760 |
0.002000 |
0.00497 |
| 2.3 |
200.00 |
0.989 |
0.00349 |
0.000761 |
0.002000 |
0.00499 |
| 2.4 |
251.00 |
0.986 |
0.00350 |
0.000763 |
0.002010 |
0.00500 |
| 2.5 |
316.00 |
0.986 |
0.00350 |
0.000763 |
0.002010 |
0.00500 |
| 2.6 |
398.00 |
0.986 |
0.00350 |
0.000763 |
0.002010 |
0.00500 |
| 2.7 |
501.00 |
0.986 |
0.00350 |
0.000763 |
0.002010 |
0.00500 |
| 2.8 |
631.00 |
0.981 |
0.00351 |
0.000765 |
0.002010 |
0.00501 |
| 2.9 |
794.00 |
0.981 |
0.00351 |
0.000765 |
0.002010 |
0.00501 |
| 3.0 |
1000.00 |
0.981 |
0.00337 |
0.000748 |
0.001900 |
0.00483 |
| 3.1 |
1260.00 |
0.977 |
0.00339 |
0.000753 |
0.001920 |
0.00487 |
| 3.2 |
1580.00 |
0.972 |
0.00341 |
0.000755 |
0.001930 |
0.00489 |
| 3.3 |
2000.00 |
0.960 |
0.00345 |
0.000766 |
0.001950 |
0.00496 |
| 3.4 |
2510.00 |
0.956 |
0.00347 |
0.000769 |
0.001960 |
0.00497 |
| 3.5 |
3160.00 |
0.956 |
0.00331 |
0.000750 |
0.001840 |
0.00478 |
| 3.6 |
3980.00 |
0.950 |
0.00318 |
0.000735 |
0.001740 |
0.00462 |
| 3.7 |
5010.00 |
0.931 |
0.00293 |
0.000711 |
0.001540 |
0.00433 |
| 3.8 |
6310.00 |
0.914 |
0.00298 |
0.000723 |
0.001560 |
0.00440 |
| 3.9 |
7940.00 |
0.905 |
0.00302 |
0.000733 |
0.001580 |
0.00446 |
| 4.0 |
10000.00 |
0.829 |
0.00297 |
0.000761 |
0.001480 |
0.00446 |
| 4.1 |
12600.00 |
0.751 |
0.00308 |
0.000817 |
0.001480 |
0.00468 |
| 4.2 |
15800.00 |
0.683 |
0.00277 |
0.000813 |
0.001180 |
0.00436 |
| 4.3 |
20000.00 |
0.558 |
0.00321 |
0.000986 |
0.001270 |
0.00514 |
| 4.4 |
25100.00 |
0.314 |
0.00400 |
0.001620 |
0.000831 |
0.00717 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.217 |
0.214 |
-0.2020 |
0.636 |
| 0.1 |
0.997 |
1.26 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.2 |
0.997 |
1.58 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.3 |
0.997 |
2.00 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.4 |
0.997 |
2.51 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.5 |
0.997 |
3.16 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.6 |
0.995 |
3.98 |
0.217 |
0.222 |
-0.2180 |
0.652 |
| 0.7 |
0.994 |
5.01 |
0.217 |
0.222 |
-0.2180 |
0.653 |
| 0.8 |
0.994 |
6.31 |
0.217 |
0.222 |
-0.2180 |
0.653 |
| 0.9 |
0.992 |
7.94 |
0.217 |
0.222 |
-0.2180 |
0.653 |
| 1.0 |
0.992 |
10.00 |
0.217 |
0.222 |
-0.2180 |
0.653 |
| 1.1 |
0.992 |
12.60 |
0.217 |
0.222 |
-0.2180 |
0.653 |
| 1.2 |
0.992 |
15.80 |
0.217 |
0.222 |
-0.2180 |
0.653 |
| 1.3 |
0.992 |
20.00 |
0.245 |
0.216 |
-0.1780 |
0.669 |
| 1.4 |
0.992 |
25.10 |
0.245 |
0.216 |
-0.1780 |
0.669 |
| 1.5 |
0.992 |
31.60 |
0.245 |
0.216 |
-0.1780 |
0.669 |
| 1.6 |
0.991 |
39.80 |
0.245 |
0.216 |
-0.1780 |
0.669 |
| 1.7 |
0.991 |
50.10 |
0.245 |
0.216 |
-0.1780 |
0.669 |
| 1.8 |
0.991 |
63.10 |
0.245 |
0.216 |
-0.1780 |
0.669 |
| 1.9 |
0.991 |
79.40 |
0.245 |
0.216 |
-0.1780 |
0.669 |
| 2.0 |
0.991 |
100.00 |
0.245 |
0.216 |
-0.1780 |
0.669 |
| 2.1 |
0.991 |
126.00 |
0.245 |
0.216 |
-0.1780 |
0.669 |
| 2.2 |
0.991 |
158.00 |
0.245 |
0.216 |
-0.1780 |
0.669 |
| 2.3 |
0.989 |
200.00 |
0.245 |
0.216 |
-0.1790 |
0.669 |
| 2.4 |
0.986 |
251.00 |
0.245 |
0.217 |
-0.1790 |
0.670 |
| 2.5 |
0.986 |
316.00 |
0.245 |
0.217 |
-0.1790 |
0.670 |
| 2.6 |
0.986 |
398.00 |
0.245 |
0.217 |
-0.1790 |
0.670 |
| 2.7 |
0.986 |
501.00 |
0.245 |
0.217 |
-0.1790 |
0.670 |
| 2.8 |
0.981 |
631.00 |
0.245 |
0.217 |
-0.1800 |
0.671 |
| 2.9 |
0.981 |
794.00 |
0.245 |
0.217 |
-0.1800 |
0.671 |
| 3.0 |
0.981 |
1000.00 |
0.261 |
0.212 |
-0.1550 |
0.677 |
| 3.1 |
0.977 |
1260.00 |
0.261 |
0.213 |
-0.1560 |
0.679 |
| 3.2 |
0.972 |
1580.00 |
0.261 |
0.213 |
-0.1570 |
0.680 |
| 3.3 |
0.960 |
2000.00 |
0.261 |
0.215 |
-0.1600 |
0.683 |
| 3.4 |
0.956 |
2510.00 |
0.261 |
0.216 |
-0.1610 |
0.684 |
| 3.5 |
0.956 |
3160.00 |
0.284 |
0.210 |
-0.1280 |
0.695 |
| 3.6 |
0.950 |
3980.00 |
0.313 |
0.204 |
-0.0872 |
0.713 |
| 3.7 |
0.931 |
5010.00 |
0.353 |
0.195 |
-0.0300 |
0.735 |
| 3.8 |
0.914 |
6310.00 |
0.353 |
0.197 |
-0.0341 |
0.740 |
| 3.9 |
0.905 |
7940.00 |
0.353 |
0.199 |
-0.0373 |
0.743 |
| 4.0 |
0.829 |
10000.00 |
0.353 |
0.204 |
-0.0470 |
0.752 |
| 4.1 |
0.751 |
12600.00 |
0.353 |
0.214 |
-0.0663 |
0.772 |
| 4.2 |
0.683 |
15800.00 |
0.356 |
0.213 |
-0.0605 |
0.773 |
| 4.3 |
0.558 |
20000.00 |
0.356 |
0.244 |
-0.1230 |
0.835 |
| 4.4 |
0.314 |
25100.00 |
0.356 |
0.369 |
-0.3680 |
1.080 |
IgG3_A244D11K169
Monotone

| 0.0 |
1.000 |
1.00 |
0.00362 |
0.000724 |
0.002200 |
0.00504 |
| 0.1 |
0.994 |
1.26 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 0.2 |
0.994 |
1.58 |
0.00350 |
0.000759 |
0.002010 |
0.00499 |
| 0.3 |
0.994 |
2.00 |
0.00350 |
0.000759 |
0.002010 |
0.00499 |
| 0.4 |
0.990 |
2.51 |
0.00350 |
0.000763 |
0.002000 |
0.00499 |
| 0.5 |
0.988 |
3.16 |
0.00350 |
0.000764 |
0.002000 |
0.00500 |
| 0.6 |
0.988 |
3.98 |
0.00350 |
0.000764 |
0.002000 |
0.00500 |
| 0.7 |
0.986 |
5.01 |
0.00342 |
0.000746 |
0.001960 |
0.00488 |
| 0.8 |
0.979 |
6.31 |
0.00342 |
0.000750 |
0.001950 |
0.00489 |
| 0.9 |
0.979 |
7.94 |
0.00342 |
0.000750 |
0.001950 |
0.00489 |
| 1.0 |
0.979 |
10.00 |
0.00342 |
0.000750 |
0.001950 |
0.00489 |
| 1.1 |
0.968 |
12.60 |
0.00342 |
0.000756 |
0.001940 |
0.00490 |
| 1.2 |
0.962 |
15.80 |
0.00342 |
0.000763 |
0.001920 |
0.00491 |
| 1.3 |
0.954 |
20.00 |
0.00342 |
0.000750 |
0.001950 |
0.00489 |
| 1.4 |
0.942 |
25.10 |
0.00342 |
0.000762 |
0.001920 |
0.00491 |
| 1.5 |
0.924 |
31.60 |
0.00342 |
0.000774 |
0.001900 |
0.00494 |
| 1.6 |
0.909 |
39.80 |
0.00342 |
0.000789 |
0.001870 |
0.00497 |
| 1.7 |
0.887 |
50.10 |
0.00342 |
0.000787 |
0.001880 |
0.00496 |
| 1.8 |
0.851 |
63.10 |
0.00342 |
0.000821 |
0.001810 |
0.00503 |
| 1.9 |
0.806 |
79.40 |
0.00342 |
0.000850 |
0.001750 |
0.00508 |
| 2.0 |
0.761 |
100.00 |
0.00319 |
0.000820 |
0.001580 |
0.00479 |
| 2.1 |
0.676 |
126.00 |
0.00317 |
0.000808 |
0.001590 |
0.00476 |
| 2.2 |
0.580 |
158.00 |
0.00317 |
0.000971 |
0.001270 |
0.00508 |
| 2.3 |
0.502 |
200.00 |
0.00317 |
0.001100 |
0.001020 |
0.00533 |
| 2.4 |
0.370 |
251.00 |
0.00317 |
0.001160 |
0.000906 |
0.00544 |
| 2.5 |
0.297 |
316.00 |
0.00317 |
0.001470 |
0.000301 |
0.00604 |
| 2.6 |
0.236 |
398.00 |
0.00317 |
0.001830 |
-0.000414 |
0.00676 |
| 2.7 |
0.193 |
501.00 |
0.00317 |
0.002150 |
-0.001030 |
0.00738 |
| 2.8 |
0.136 |
631.00 |
0.00317 |
0.002720 |
-0.002160 |
0.00850 |
| 2.9 |
0.092 |
794.00 |
0.00317 |
0.003120 |
-0.002930 |
0.00928 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.994 |
0.00362 |
0.000776 |
0.002100 |
0.00514 |
| 0.2 |
1.58 |
0.994 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 0.3 |
2.00 |
0.994 |
0.00348 |
0.000759 |
0.001990 |
0.00497 |
| 0.4 |
2.51 |
0.990 |
0.00351 |
0.000763 |
0.002010 |
0.00500 |
| 0.5 |
3.16 |
0.988 |
0.00351 |
0.000764 |
0.002020 |
0.00501 |
| 0.6 |
3.98 |
0.988 |
0.00351 |
0.000764 |
0.002020 |
0.00501 |
| 0.7 |
5.01 |
0.986 |
0.00337 |
0.000746 |
0.001900 |
0.00483 |
| 0.8 |
6.31 |
0.979 |
0.00339 |
0.000750 |
0.001920 |
0.00486 |
| 0.9 |
7.94 |
0.979 |
0.00339 |
0.000750 |
0.001920 |
0.00486 |
| 1.0 |
10.00 |
0.979 |
0.00339 |
0.000750 |
0.001920 |
0.00486 |
| 1.1 |
12.60 |
0.968 |
0.00341 |
0.000756 |
0.001930 |
0.00489 |
| 1.2 |
15.80 |
0.962 |
0.00344 |
0.000763 |
0.001940 |
0.00493 |
| 1.3 |
20.00 |
0.954 |
0.00331 |
0.000750 |
0.001840 |
0.00478 |
| 1.4 |
25.10 |
0.942 |
0.00337 |
0.000762 |
0.001870 |
0.00486 |
| 1.5 |
31.60 |
0.924 |
0.00342 |
0.000774 |
0.001900 |
0.00494 |
| 1.6 |
39.80 |
0.909 |
0.00348 |
0.000789 |
0.001930 |
0.00503 |
| 1.7 |
50.10 |
0.887 |
0.00339 |
0.000787 |
0.001850 |
0.00494 |
| 1.8 |
63.10 |
0.851 |
0.00354 |
0.000821 |
0.001930 |
0.00515 |
| 1.9 |
79.40 |
0.806 |
0.00357 |
0.000850 |
0.001900 |
0.00523 |
| 2.0 |
100.00 |
0.761 |
0.00319 |
0.000820 |
0.001580 |
0.00479 |
| 2.1 |
126.00 |
0.676 |
0.00275 |
0.000808 |
0.001170 |
0.00434 |
| 2.2 |
158.00 |
0.580 |
0.00327 |
0.000971 |
0.001360 |
0.00517 |
| 2.3 |
200.00 |
0.502 |
0.00355 |
0.001100 |
0.001390 |
0.00570 |
| 2.4 |
251.00 |
0.370 |
0.00306 |
0.001160 |
0.000795 |
0.00533 |
| 2.5 |
316.00 |
0.297 |
0.00381 |
0.001470 |
0.000940 |
0.00668 |
| 2.6 |
398.00 |
0.236 |
0.00438 |
0.001830 |
0.000796 |
0.00797 |
| 2.7 |
501.00 |
0.193 |
0.00472 |
0.002150 |
0.000519 |
0.00893 |
| 2.8 |
631.00 |
0.136 |
0.00489 |
0.002720 |
-0.000440 |
0.01020 |
| 2.9 |
794.00 |
0.092 |
0.00473 |
0.003120 |
-0.001380 |
0.01080 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.218 |
0.214 |
-0.201 |
0.637 |
| 0.1 |
0.994 |
1.26 |
0.218 |
0.222 |
-0.217 |
0.653 |
| 0.2 |
0.994 |
1.58 |
0.244 |
0.216 |
-0.180 |
0.667 |
| 0.3 |
0.994 |
2.00 |
0.244 |
0.216 |
-0.180 |
0.667 |
| 0.4 |
0.990 |
2.51 |
0.244 |
0.217 |
-0.181 |
0.669 |
| 0.5 |
0.988 |
3.16 |
0.244 |
0.217 |
-0.181 |
0.669 |
| 0.6 |
0.988 |
3.98 |
0.244 |
0.217 |
-0.181 |
0.669 |
| 0.7 |
0.986 |
5.01 |
0.261 |
0.212 |
-0.154 |
0.677 |
| 0.8 |
0.979 |
6.31 |
0.261 |
0.213 |
-0.155 |
0.678 |
| 0.9 |
0.979 |
7.94 |
0.261 |
0.213 |
-0.155 |
0.678 |
| 1.0 |
0.979 |
10.00 |
0.261 |
0.213 |
-0.155 |
0.678 |
| 1.1 |
0.968 |
12.60 |
0.261 |
0.214 |
-0.157 |
0.680 |
| 1.2 |
0.962 |
15.80 |
0.261 |
0.215 |
-0.160 |
0.682 |
| 1.3 |
0.954 |
20.00 |
0.261 |
0.213 |
-0.155 |
0.678 |
| 1.4 |
0.942 |
25.10 |
0.261 |
0.215 |
-0.159 |
0.682 |
| 1.5 |
0.924 |
31.60 |
0.261 |
0.217 |
-0.163 |
0.686 |
| 1.6 |
0.909 |
39.80 |
0.261 |
0.219 |
-0.168 |
0.691 |
| 1.7 |
0.887 |
50.10 |
0.261 |
0.219 |
-0.167 |
0.690 |
| 1.8 |
0.851 |
63.10 |
0.261 |
0.225 |
-0.179 |
0.701 |
| 1.9 |
0.806 |
79.40 |
0.261 |
0.229 |
-0.188 |
0.711 |
| 2.0 |
0.761 |
100.00 |
0.312 |
0.219 |
-0.117 |
0.740 |
| 2.1 |
0.676 |
126.00 |
0.314 |
0.216 |
-0.109 |
0.738 |
| 2.2 |
0.580 |
158.00 |
0.314 |
0.246 |
-0.167 |
0.796 |
| 2.3 |
0.502 |
200.00 |
0.314 |
0.270 |
-0.214 |
0.843 |
| 2.4 |
0.370 |
251.00 |
0.314 |
0.281 |
-0.236 |
0.864 |
| 2.5 |
0.297 |
316.00 |
0.314 |
0.341 |
-0.355 |
0.983 |
| 2.6 |
0.236 |
398.00 |
0.314 |
0.416 |
-0.500 |
1.130 |
| 2.7 |
0.193 |
501.00 |
0.314 |
0.481 |
-0.628 |
1.260 |
| 2.8 |
0.136 |
631.00 |
0.314 |
0.601 |
-0.864 |
1.490 |
| 2.9 |
0.092 |
794.00 |
0.314 |
0.685 |
-1.030 |
1.660 |
IgG3_gp70ClAEV1V2
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00361 |
0.000724 |
0.002190 |
0.00503 |
| 0.1 |
0.9840 |
1.26 |
0.00354 |
0.000765 |
0.002040 |
0.00504 |
| 0.2 |
0.9840 |
1.58 |
0.00354 |
0.000765 |
0.002040 |
0.00504 |
| 0.3 |
0.9840 |
2.00 |
0.00354 |
0.000765 |
0.002040 |
0.00504 |
| 0.4 |
0.9830 |
2.51 |
0.00354 |
0.000766 |
0.002040 |
0.00504 |
| 0.5 |
0.9810 |
3.16 |
0.00354 |
0.000767 |
0.002040 |
0.00504 |
| 0.6 |
0.9810 |
3.98 |
0.00354 |
0.000767 |
0.002040 |
0.00504 |
| 0.7 |
0.9810 |
5.01 |
0.00354 |
0.000767 |
0.002040 |
0.00504 |
| 0.8 |
0.9770 |
6.31 |
0.00354 |
0.000770 |
0.002030 |
0.00505 |
| 0.9 |
0.9730 |
7.94 |
0.00354 |
0.000772 |
0.002030 |
0.00505 |
| 1.0 |
0.9730 |
10.00 |
0.00354 |
0.000772 |
0.002030 |
0.00505 |
| 1.1 |
0.9660 |
12.60 |
0.00354 |
0.000776 |
0.002020 |
0.00506 |
| 1.2 |
0.9660 |
15.80 |
0.00354 |
0.000776 |
0.002020 |
0.00506 |
| 1.3 |
0.9660 |
20.00 |
0.00354 |
0.000776 |
0.002020 |
0.00506 |
| 1.4 |
0.9660 |
25.10 |
0.00354 |
0.000776 |
0.002020 |
0.00506 |
| 1.5 |
0.9630 |
31.60 |
0.00354 |
0.000778 |
0.002010 |
0.00506 |
| 1.6 |
0.9530 |
39.80 |
0.00335 |
0.000750 |
0.001880 |
0.00482 |
| 1.7 |
0.9490 |
50.10 |
0.00335 |
0.000752 |
0.001880 |
0.00482 |
| 1.8 |
0.9470 |
63.10 |
0.00335 |
0.000753 |
0.001870 |
0.00483 |
| 1.9 |
0.9390 |
79.40 |
0.00335 |
0.000760 |
0.001860 |
0.00484 |
| 2.0 |
0.9330 |
100.00 |
0.00335 |
0.000764 |
0.001850 |
0.00485 |
| 2.1 |
0.9110 |
126.00 |
0.00335 |
0.000763 |
0.001850 |
0.00485 |
| 2.2 |
0.8890 |
158.00 |
0.00335 |
0.000785 |
0.001810 |
0.00489 |
| 2.3 |
0.8780 |
200.00 |
0.00335 |
0.000794 |
0.001790 |
0.00491 |
| 2.4 |
0.8660 |
251.00 |
0.00335 |
0.000763 |
0.001860 |
0.00484 |
| 2.5 |
0.8320 |
316.00 |
0.00335 |
0.000791 |
0.001800 |
0.00490 |
| 2.6 |
0.8070 |
398.00 |
0.00335 |
0.000792 |
0.001800 |
0.00490 |
| 2.7 |
0.7200 |
501.00 |
0.00335 |
0.000847 |
0.001690 |
0.00501 |
| 2.8 |
0.6820 |
631.00 |
0.00335 |
0.000895 |
0.001590 |
0.00511 |
| 2.9 |
0.6430 |
794.00 |
0.00335 |
0.000888 |
0.001610 |
0.00509 |
| 3.0 |
0.5850 |
1000.00 |
0.00335 |
0.000980 |
0.001430 |
0.00527 |
| 3.1 |
0.5130 |
1260.00 |
0.00335 |
0.001050 |
0.001290 |
0.00541 |
| 3.2 |
0.4480 |
1580.00 |
0.00335 |
0.001180 |
0.001050 |
0.00565 |
| 3.3 |
0.3480 |
2000.00 |
0.00335 |
0.001430 |
0.000553 |
0.00615 |
| 3.4 |
0.3010 |
2510.00 |
0.00335 |
0.001630 |
0.000157 |
0.00654 |
| 3.5 |
0.2480 |
3160.00 |
0.00335 |
0.001910 |
-0.000388 |
0.00709 |
| 3.6 |
0.2030 |
3980.00 |
0.00335 |
0.002040 |
-0.000658 |
0.00736 |
| 3.7 |
0.1640 |
5010.00 |
0.00335 |
0.002440 |
-0.001430 |
0.00813 |
| 3.8 |
0.1150 |
6310.00 |
0.00335 |
0.002940 |
-0.002420 |
0.00912 |
| 3.9 |
0.0801 |
7940.00 |
0.00335 |
0.004710 |
-0.005880 |
0.01260 |
| 4.0 |
0.0654 |
10000.00 |
0.00335 |
0.006400 |
-0.009200 |
0.01590 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.9840 |
0.00352 |
0.000765 |
0.002020 |
0.00501 |
| 0.2 |
1.58 |
0.9840 |
0.00352 |
0.000765 |
0.002020 |
0.00501 |
| 0.3 |
2.00 |
0.9840 |
0.00352 |
0.000765 |
0.002020 |
0.00501 |
| 0.4 |
2.51 |
0.9830 |
0.00352 |
0.000766 |
0.002020 |
0.00502 |
| 0.5 |
3.16 |
0.9810 |
0.00352 |
0.000767 |
0.002020 |
0.00502 |
| 0.6 |
3.98 |
0.9810 |
0.00352 |
0.000767 |
0.002020 |
0.00502 |
| 0.7 |
5.01 |
0.9810 |
0.00352 |
0.000767 |
0.002020 |
0.00502 |
| 0.8 |
6.31 |
0.9770 |
0.00354 |
0.000770 |
0.002030 |
0.00505 |
| 0.9 |
7.94 |
0.9730 |
0.00355 |
0.000772 |
0.002030 |
0.00506 |
| 1.0 |
10.00 |
0.9730 |
0.00355 |
0.000772 |
0.002030 |
0.00506 |
| 1.1 |
12.60 |
0.9660 |
0.00356 |
0.000776 |
0.002040 |
0.00508 |
| 1.2 |
15.80 |
0.9660 |
0.00356 |
0.000776 |
0.002040 |
0.00508 |
| 1.3 |
20.00 |
0.9660 |
0.00356 |
0.000776 |
0.002040 |
0.00508 |
| 1.4 |
25.10 |
0.9660 |
0.00356 |
0.000776 |
0.002040 |
0.00508 |
| 1.5 |
31.60 |
0.9630 |
0.00358 |
0.000778 |
0.002050 |
0.00510 |
| 1.6 |
39.80 |
0.9530 |
0.00331 |
0.000750 |
0.001840 |
0.00478 |
| 1.7 |
50.10 |
0.9490 |
0.00332 |
0.000752 |
0.001850 |
0.00480 |
| 1.8 |
63.10 |
0.9470 |
0.00333 |
0.000753 |
0.001850 |
0.00480 |
| 1.9 |
79.40 |
0.9390 |
0.00336 |
0.000760 |
0.001870 |
0.00485 |
| 2.0 |
100.00 |
0.9330 |
0.00337 |
0.000764 |
0.001870 |
0.00487 |
| 2.1 |
126.00 |
0.9110 |
0.00329 |
0.000763 |
0.001800 |
0.00479 |
| 2.2 |
158.00 |
0.8890 |
0.00338 |
0.000785 |
0.001840 |
0.00492 |
| 2.3 |
200.00 |
0.8780 |
0.00342 |
0.000794 |
0.001860 |
0.00497 |
| 2.4 |
251.00 |
0.8660 |
0.00314 |
0.000763 |
0.001640 |
0.00463 |
| 2.5 |
316.00 |
0.8320 |
0.00324 |
0.000791 |
0.001690 |
0.00480 |
| 2.6 |
398.00 |
0.8070 |
0.00316 |
0.000792 |
0.001610 |
0.00471 |
| 2.7 |
501.00 |
0.7200 |
0.00317 |
0.000847 |
0.001510 |
0.00483 |
| 2.8 |
631.00 |
0.6820 |
0.00336 |
0.000895 |
0.001600 |
0.00511 |
| 2.9 |
794.00 |
0.6430 |
0.00313 |
0.000888 |
0.001390 |
0.00487 |
| 3.0 |
1000.00 |
0.5850 |
0.00343 |
0.000980 |
0.001510 |
0.00536 |
| 3.1 |
1260.00 |
0.5130 |
0.00341 |
0.001050 |
0.001350 |
0.00546 |
| 3.2 |
1580.00 |
0.4480 |
0.00364 |
0.001180 |
0.001340 |
0.00594 |
| 3.3 |
2000.00 |
0.3480 |
0.00418 |
0.001430 |
0.001380 |
0.00697 |
| 3.4 |
2510.00 |
0.3010 |
0.00448 |
0.001630 |
0.001280 |
0.00767 |
| 3.5 |
3160.00 |
0.2480 |
0.00486 |
0.001910 |
0.001120 |
0.00859 |
| 3.6 |
3980.00 |
0.2030 |
0.00456 |
0.002040 |
0.000557 |
0.00857 |
| 3.7 |
5010.00 |
0.1640 |
0.00499 |
0.002440 |
0.000211 |
0.00976 |
| 3.8 |
6310.00 |
0.1150 |
0.00528 |
0.002940 |
-0.000492 |
0.01100 |
| 3.9 |
7940.00 |
0.0801 |
0.00811 |
0.004710 |
-0.001120 |
0.01730 |
| 4.0 |
10000.00 |
0.0654 |
0.00987 |
0.006400 |
-0.002680 |
0.02240 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.220 |
0.214 |
-0.199 |
0.638 |
| 0.1 |
0.9840 |
1.26 |
0.235 |
0.218 |
-0.192 |
0.663 |
| 0.2 |
0.9840 |
1.58 |
0.235 |
0.218 |
-0.192 |
0.663 |
| 0.3 |
0.9840 |
2.00 |
0.235 |
0.218 |
-0.192 |
0.663 |
| 0.4 |
0.9830 |
2.51 |
0.235 |
0.218 |
-0.193 |
0.663 |
| 0.5 |
0.9810 |
3.16 |
0.235 |
0.218 |
-0.193 |
0.663 |
| 0.6 |
0.9810 |
3.98 |
0.235 |
0.218 |
-0.193 |
0.663 |
| 0.7 |
0.9810 |
5.01 |
0.235 |
0.218 |
-0.193 |
0.663 |
| 0.8 |
0.9770 |
6.31 |
0.235 |
0.219 |
-0.194 |
0.664 |
| 0.9 |
0.9730 |
7.94 |
0.235 |
0.219 |
-0.195 |
0.665 |
| 1.0 |
0.9730 |
10.00 |
0.235 |
0.219 |
-0.195 |
0.665 |
| 1.1 |
0.9660 |
12.60 |
0.235 |
0.220 |
-0.196 |
0.666 |
| 1.2 |
0.9660 |
15.80 |
0.235 |
0.220 |
-0.196 |
0.666 |
| 1.3 |
0.9660 |
20.00 |
0.235 |
0.220 |
-0.196 |
0.666 |
| 1.4 |
0.9660 |
25.10 |
0.235 |
0.220 |
-0.196 |
0.666 |
| 1.5 |
0.9630 |
31.60 |
0.235 |
0.220 |
-0.197 |
0.667 |
| 1.6 |
0.9530 |
39.80 |
0.276 |
0.211 |
-0.137 |
0.689 |
| 1.7 |
0.9490 |
50.10 |
0.276 |
0.211 |
-0.138 |
0.690 |
| 1.8 |
0.9470 |
63.10 |
0.276 |
0.211 |
-0.138 |
0.690 |
| 1.9 |
0.9390 |
79.40 |
0.276 |
0.213 |
-0.141 |
0.693 |
| 2.0 |
0.9330 |
100.00 |
0.276 |
0.213 |
-0.142 |
0.694 |
| 2.1 |
0.9110 |
126.00 |
0.276 |
0.213 |
-0.141 |
0.694 |
| 2.2 |
0.8890 |
158.00 |
0.276 |
0.217 |
-0.149 |
0.701 |
| 2.3 |
0.8780 |
200.00 |
0.276 |
0.218 |
-0.152 |
0.704 |
| 2.4 |
0.8660 |
251.00 |
0.276 |
0.213 |
-0.141 |
0.693 |
| 2.5 |
0.8320 |
316.00 |
0.276 |
0.218 |
-0.151 |
0.703 |
| 2.6 |
0.8070 |
398.00 |
0.276 |
0.218 |
-0.151 |
0.703 |
| 2.7 |
0.7200 |
501.00 |
0.276 |
0.227 |
-0.170 |
0.722 |
| 2.8 |
0.6820 |
631.00 |
0.276 |
0.236 |
-0.186 |
0.738 |
| 2.9 |
0.6430 |
794.00 |
0.276 |
0.235 |
-0.184 |
0.736 |
| 3.0 |
0.5850 |
1000.00 |
0.276 |
0.251 |
-0.216 |
0.768 |
| 3.1 |
0.5130 |
1260.00 |
0.276 |
0.264 |
-0.241 |
0.793 |
| 3.2 |
0.4480 |
1580.00 |
0.276 |
0.288 |
-0.288 |
0.840 |
| 3.3 |
0.3480 |
2000.00 |
0.276 |
0.337 |
-0.384 |
0.936 |
| 3.4 |
0.3010 |
2510.00 |
0.276 |
0.377 |
-0.463 |
1.010 |
| 3.5 |
0.2480 |
3160.00 |
0.276 |
0.434 |
-0.574 |
1.130 |
| 3.6 |
0.2030 |
3980.00 |
0.276 |
0.462 |
-0.629 |
1.180 |
| 3.7 |
0.1640 |
5010.00 |
0.276 |
0.544 |
-0.789 |
1.340 |
| 3.8 |
0.1150 |
6310.00 |
0.276 |
0.650 |
-0.998 |
1.550 |
| 3.9 |
0.0801 |
7940.00 |
0.276 |
1.030 |
-1.740 |
2.290 |
| 4.0 |
0.0654 |
10000.00 |
0.276 |
1.390 |
-2.450 |
3.000 |
IgG3_gp70V1V2A
Monotone

| 0.0 |
1.000 |
1.00 |
0.00373 |
0.000724 |
0.002310 |
0.00515 |
| 0.1 |
0.931 |
1.26 |
0.00373 |
0.000820 |
0.002120 |
0.00534 |
| 0.2 |
0.923 |
1.58 |
0.00373 |
0.000826 |
0.002110 |
0.00535 |
| 0.3 |
0.922 |
2.00 |
0.00373 |
0.000827 |
0.002110 |
0.00535 |
| 0.4 |
0.916 |
2.51 |
0.00369 |
0.000813 |
0.002100 |
0.00529 |
| 0.5 |
0.914 |
3.16 |
0.00369 |
0.000815 |
0.002100 |
0.00529 |
| 0.6 |
0.894 |
3.98 |
0.00369 |
0.000829 |
0.002070 |
0.00532 |
| 0.7 |
0.882 |
5.01 |
0.00369 |
0.000837 |
0.002050 |
0.00533 |
| 0.8 |
0.867 |
6.31 |
0.00364 |
0.000829 |
0.002020 |
0.00527 |
| 0.9 |
0.849 |
7.94 |
0.00355 |
0.000827 |
0.001930 |
0.00517 |
| 1.0 |
0.824 |
10.00 |
0.00342 |
0.000779 |
0.001890 |
0.00494 |
| 1.1 |
0.778 |
12.60 |
0.00342 |
0.000831 |
0.001790 |
0.00505 |
| 1.2 |
0.722 |
15.80 |
0.00342 |
0.000840 |
0.001770 |
0.00507 |
| 1.3 |
0.668 |
20.00 |
0.00342 |
0.000910 |
0.001630 |
0.00520 |
| 1.4 |
0.565 |
25.10 |
0.00342 |
0.001030 |
0.001410 |
0.00543 |
| 1.5 |
0.518 |
31.60 |
0.00342 |
0.001060 |
0.001330 |
0.00551 |
| 1.6 |
0.471 |
39.80 |
0.00342 |
0.001130 |
0.001210 |
0.00562 |
| 1.7 |
0.385 |
50.10 |
0.00342 |
0.001260 |
0.000954 |
0.00588 |
| 1.8 |
0.318 |
63.10 |
0.00342 |
0.001200 |
0.001070 |
0.00577 |
| 1.9 |
0.241 |
79.40 |
0.00342 |
0.001690 |
0.000108 |
0.00673 |
| 2.0 |
0.213 |
100.00 |
0.00342 |
0.002060 |
-0.000626 |
0.00746 |
| 2.1 |
0.179 |
126.00 |
0.00342 |
0.002120 |
-0.000732 |
0.00757 |
| 2.2 |
0.122 |
158.00 |
0.00342 |
0.002650 |
-0.001780 |
0.00862 |
| 2.3 |
0.113 |
200.00 |
0.00342 |
0.002400 |
-0.001290 |
0.00813 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.931 |
0.00376 |
0.000820 |
0.002150 |
0.00536 |
| 0.2 |
1.58 |
0.923 |
0.00378 |
0.000826 |
0.002160 |
0.00540 |
| 0.3 |
2.00 |
0.922 |
0.00378 |
0.000827 |
0.002160 |
0.00541 |
| 0.4 |
2.51 |
0.916 |
0.00365 |
0.000813 |
0.002060 |
0.00525 |
| 0.5 |
3.16 |
0.914 |
0.00366 |
0.000815 |
0.002060 |
0.00525 |
| 0.6 |
3.98 |
0.894 |
0.00372 |
0.000829 |
0.002090 |
0.00534 |
| 0.7 |
5.01 |
0.882 |
0.00375 |
0.000837 |
0.002110 |
0.00539 |
| 0.8 |
6.31 |
0.867 |
0.00364 |
0.000829 |
0.002020 |
0.00527 |
| 0.9 |
7.94 |
0.849 |
0.00355 |
0.000827 |
0.001930 |
0.00517 |
| 1.0 |
10.00 |
0.824 |
0.00312 |
0.000779 |
0.001590 |
0.00464 |
| 1.1 |
12.60 |
0.778 |
0.00331 |
0.000831 |
0.001680 |
0.00494 |
| 1.2 |
15.80 |
0.722 |
0.00316 |
0.000840 |
0.001510 |
0.00481 |
| 1.3 |
20.00 |
0.668 |
0.00341 |
0.000910 |
0.001630 |
0.00520 |
| 1.4 |
25.10 |
0.565 |
0.00359 |
0.001030 |
0.001580 |
0.00560 |
| 1.5 |
31.60 |
0.518 |
0.00359 |
0.001060 |
0.001500 |
0.00568 |
| 1.6 |
39.80 |
0.471 |
0.00364 |
0.001130 |
0.001430 |
0.00584 |
| 1.7 |
50.10 |
0.385 |
0.00371 |
0.001260 |
0.001250 |
0.00617 |
| 1.8 |
63.10 |
0.318 |
0.00277 |
0.001200 |
0.000426 |
0.00512 |
| 1.9 |
79.40 |
0.241 |
0.00353 |
0.001690 |
0.000218 |
0.00684 |
| 2.0 |
100.00 |
0.213 |
0.00427 |
0.002060 |
0.000222 |
0.00831 |
| 2.1 |
126.00 |
0.179 |
0.00396 |
0.002120 |
-0.000188 |
0.00811 |
| 2.2 |
158.00 |
0.122 |
0.00478 |
0.002650 |
-0.000423 |
0.00998 |
| 2.3 |
200.00 |
0.113 |
0.00384 |
0.002400 |
-0.000872 |
0.00855 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.194 |
0.217 |
-0.232 |
0.619 |
| 0.1 |
0.931 |
1.26 |
0.194 |
0.232 |
-0.262 |
0.649 |
| 0.2 |
0.923 |
1.58 |
0.194 |
0.233 |
-0.264 |
0.651 |
| 0.3 |
0.922 |
2.00 |
0.194 |
0.233 |
-0.264 |
0.651 |
| 0.4 |
0.916 |
2.51 |
0.202 |
0.230 |
-0.249 |
0.653 |
| 0.5 |
0.914 |
3.16 |
0.202 |
0.230 |
-0.250 |
0.653 |
| 0.6 |
0.894 |
3.98 |
0.202 |
0.233 |
-0.254 |
0.658 |
| 0.7 |
0.882 |
5.01 |
0.202 |
0.234 |
-0.257 |
0.661 |
| 0.8 |
0.867 |
6.31 |
0.213 |
0.231 |
-0.241 |
0.667 |
| 0.9 |
0.849 |
7.94 |
0.232 |
0.229 |
-0.216 |
0.681 |
| 1.0 |
0.824 |
10.00 |
0.261 |
0.217 |
-0.165 |
0.687 |
| 1.1 |
0.778 |
12.60 |
0.261 |
0.226 |
-0.182 |
0.705 |
| 1.2 |
0.722 |
15.80 |
0.261 |
0.228 |
-0.185 |
0.708 |
| 1.3 |
0.668 |
20.00 |
0.261 |
0.240 |
-0.209 |
0.732 |
| 1.4 |
0.565 |
25.10 |
0.261 |
0.261 |
-0.250 |
0.773 |
| 1.5 |
0.518 |
31.60 |
0.261 |
0.268 |
-0.264 |
0.787 |
| 1.6 |
0.471 |
39.80 |
0.261 |
0.279 |
-0.286 |
0.809 |
| 1.7 |
0.385 |
50.10 |
0.261 |
0.305 |
-0.336 |
0.858 |
| 1.8 |
0.318 |
63.10 |
0.261 |
0.293 |
-0.313 |
0.836 |
| 1.9 |
0.241 |
79.40 |
0.261 |
0.390 |
-0.503 |
1.030 |
| 2.0 |
0.213 |
100.00 |
0.261 |
0.467 |
-0.653 |
1.180 |
| 2.1 |
0.179 |
126.00 |
0.261 |
0.478 |
-0.675 |
1.200 |
| 2.2 |
0.122 |
158.00 |
0.261 |
0.590 |
-0.894 |
1.420 |
| 2.3 |
0.113 |
200.00 |
0.261 |
0.537 |
-0.792 |
1.310 |
IgG3_gp70V1V2AP
Monotone

| 0.0 |
1.000 |
1.00 |
0.00370 |
0.000724 |
0.002280 |
0.00512 |
| 0.1 |
0.932 |
1.26 |
0.00370 |
0.000806 |
0.002120 |
0.00527 |
| 0.2 |
0.932 |
1.58 |
0.00370 |
0.000806 |
0.002120 |
0.00527 |
| 0.3 |
0.916 |
2.00 |
0.00370 |
0.000820 |
0.002090 |
0.00530 |
| 0.4 |
0.907 |
2.51 |
0.00370 |
0.000814 |
0.002100 |
0.00529 |
| 0.5 |
0.894 |
3.16 |
0.00370 |
0.000822 |
0.002080 |
0.00531 |
| 0.6 |
0.871 |
3.98 |
0.00370 |
0.000839 |
0.002050 |
0.00534 |
| 0.7 |
0.846 |
5.01 |
0.00357 |
0.000822 |
0.001950 |
0.00518 |
| 0.8 |
0.831 |
6.31 |
0.00357 |
0.000839 |
0.001920 |
0.00521 |
| 0.9 |
0.787 |
7.94 |
0.00340 |
0.000832 |
0.001770 |
0.00504 |
| 1.0 |
0.745 |
10.00 |
0.00340 |
0.000826 |
0.001790 |
0.00502 |
| 1.1 |
0.709 |
12.60 |
0.00340 |
0.000874 |
0.001690 |
0.00512 |
| 1.2 |
0.648 |
15.80 |
0.00340 |
0.000935 |
0.001570 |
0.00524 |
| 1.3 |
0.580 |
20.00 |
0.00340 |
0.000983 |
0.001480 |
0.00533 |
| 1.4 |
0.473 |
25.10 |
0.00340 |
0.001110 |
0.001240 |
0.00557 |
| 1.5 |
0.413 |
31.60 |
0.00337 |
0.001140 |
0.001130 |
0.00561 |
| 1.6 |
0.336 |
39.80 |
0.00337 |
0.001180 |
0.001050 |
0.00569 |
| 1.7 |
0.291 |
50.10 |
0.00337 |
0.001300 |
0.000822 |
0.00592 |
| 1.8 |
0.219 |
63.10 |
0.00337 |
0.001590 |
0.000262 |
0.00648 |
| 1.9 |
0.178 |
79.40 |
0.00337 |
0.002100 |
-0.000736 |
0.00748 |
| 2.0 |
0.165 |
100.00 |
0.00320 |
0.001870 |
-0.000460 |
0.00686 |
| 2.1 |
0.149 |
126.00 |
0.00320 |
0.002190 |
-0.001100 |
0.00750 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.932 |
0.00370 |
0.000806 |
0.002120 |
0.00528 |
| 0.2 |
1.58 |
0.932 |
0.00370 |
0.000806 |
0.002120 |
0.00528 |
| 0.3 |
2.00 |
0.916 |
0.00376 |
0.000820 |
0.002150 |
0.00537 |
| 0.4 |
2.51 |
0.907 |
0.00366 |
0.000814 |
0.002060 |
0.00526 |
| 0.5 |
3.16 |
0.894 |
0.00369 |
0.000822 |
0.002080 |
0.00530 |
| 0.6 |
3.98 |
0.871 |
0.00376 |
0.000839 |
0.002120 |
0.00541 |
| 0.7 |
5.01 |
0.846 |
0.00353 |
0.000822 |
0.001920 |
0.00514 |
| 0.8 |
6.31 |
0.831 |
0.00360 |
0.000839 |
0.001960 |
0.00525 |
| 0.9 |
7.94 |
0.787 |
0.00340 |
0.000832 |
0.001760 |
0.00503 |
| 1.0 |
10.00 |
0.745 |
0.00320 |
0.000826 |
0.001580 |
0.00481 |
| 1.1 |
12.60 |
0.709 |
0.00337 |
0.000874 |
0.001660 |
0.00508 |
| 1.2 |
15.80 |
0.648 |
0.00350 |
0.000935 |
0.001660 |
0.00533 |
| 1.3 |
20.00 |
0.580 |
0.00344 |
0.000983 |
0.001520 |
0.00537 |
| 1.4 |
25.10 |
0.473 |
0.00357 |
0.001110 |
0.001400 |
0.00574 |
| 1.5 |
31.60 |
0.413 |
0.00337 |
0.001140 |
0.001130 |
0.00561 |
| 1.6 |
39.80 |
0.336 |
0.00294 |
0.001180 |
0.000623 |
0.00526 |
| 1.7 |
50.10 |
0.291 |
0.00298 |
0.001300 |
0.000432 |
0.00553 |
| 1.8 |
63.10 |
0.219 |
0.00333 |
0.001590 |
0.000217 |
0.00643 |
| 1.9 |
79.40 |
0.178 |
0.00428 |
0.002100 |
0.000173 |
0.00839 |
| 2.0 |
100.00 |
0.165 |
0.00294 |
0.001870 |
-0.000723 |
0.00659 |
| 2.1 |
126.00 |
0.149 |
0.00346 |
0.002190 |
-0.000840 |
0.00776 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.201 |
0.216 |
-0.222 |
0.624 |
| 0.1 |
0.932 |
1.26 |
0.201 |
0.229 |
-0.247 |
0.650 |
| 0.2 |
0.932 |
1.58 |
0.201 |
0.229 |
-0.247 |
0.650 |
| 0.3 |
0.916 |
2.00 |
0.201 |
0.231 |
-0.252 |
0.655 |
| 0.4 |
0.907 |
2.51 |
0.201 |
0.230 |
-0.250 |
0.653 |
| 0.5 |
0.894 |
3.16 |
0.201 |
0.232 |
-0.253 |
0.655 |
| 0.6 |
0.871 |
3.98 |
0.201 |
0.235 |
-0.258 |
0.661 |
| 0.7 |
0.846 |
5.01 |
0.229 |
0.228 |
-0.218 |
0.677 |
| 0.8 |
0.831 |
6.31 |
0.229 |
0.231 |
-0.224 |
0.683 |
| 0.9 |
0.787 |
7.94 |
0.264 |
0.226 |
-0.179 |
0.707 |
| 1.0 |
0.745 |
10.00 |
0.264 |
0.225 |
-0.177 |
0.705 |
| 1.1 |
0.709 |
12.60 |
0.264 |
0.233 |
-0.193 |
0.722 |
| 1.2 |
0.648 |
15.80 |
0.264 |
0.244 |
-0.214 |
0.743 |
| 1.3 |
0.580 |
20.00 |
0.264 |
0.253 |
-0.231 |
0.760 |
| 1.4 |
0.473 |
25.10 |
0.264 |
0.275 |
-0.276 |
0.804 |
| 1.5 |
0.413 |
31.60 |
0.272 |
0.282 |
-0.280 |
0.824 |
| 1.6 |
0.336 |
39.80 |
0.272 |
0.289 |
-0.296 |
0.839 |
| 1.7 |
0.291 |
50.10 |
0.272 |
0.312 |
-0.340 |
0.883 |
| 1.8 |
0.219 |
63.10 |
0.272 |
0.369 |
-0.451 |
0.994 |
| 1.9 |
0.178 |
79.40 |
0.272 |
0.473 |
-0.655 |
1.200 |
| 2.0 |
0.165 |
100.00 |
0.309 |
0.423 |
-0.521 |
1.140 |
| 2.1 |
0.149 |
126.00 |
0.309 |
0.491 |
-0.654 |
1.270 |
IgG3_gp70V1V2C
Monotone

| 0.0 |
1.000 |
1.00 |
0.00361 |
0.000724 |
2.19e-03 |
0.00503 |
| 0.1 |
0.927 |
1.26 |
0.00313 |
0.000729 |
1.70e-03 |
0.00456 |
| 0.2 |
0.922 |
1.58 |
0.00313 |
0.000733 |
1.70e-03 |
0.00457 |
| 0.3 |
0.918 |
2.00 |
0.00313 |
0.000736 |
1.69e-03 |
0.00458 |
| 0.4 |
0.914 |
2.51 |
0.00313 |
0.000741 |
1.68e-03 |
0.00459 |
| 0.5 |
0.907 |
3.16 |
0.00313 |
0.000750 |
1.66e-03 |
0.00460 |
| 0.6 |
0.888 |
3.98 |
0.00313 |
0.000746 |
1.67e-03 |
0.00460 |
| 0.7 |
0.874 |
5.01 |
0.00313 |
0.000755 |
1.65e-03 |
0.00461 |
| 0.8 |
0.851 |
6.31 |
0.00313 |
0.000751 |
1.66e-03 |
0.00461 |
| 0.9 |
0.827 |
7.94 |
0.00313 |
0.000773 |
1.62e-03 |
0.00465 |
| 1.0 |
0.801 |
10.00 |
0.00313 |
0.000774 |
1.62e-03 |
0.00465 |
| 1.1 |
0.753 |
12.60 |
0.00313 |
0.000826 |
1.51e-03 |
0.00475 |
| 1.2 |
0.717 |
15.80 |
0.00313 |
0.000838 |
1.49e-03 |
0.00478 |
| 1.3 |
0.656 |
20.00 |
0.00313 |
0.000905 |
1.36e-03 |
0.00491 |
| 1.4 |
0.605 |
25.10 |
0.00313 |
0.000875 |
1.42e-03 |
0.00485 |
| 1.5 |
0.544 |
31.60 |
0.00313 |
0.000973 |
1.23e-03 |
0.00504 |
| 1.6 |
0.490 |
39.80 |
0.00313 |
0.001050 |
1.08e-03 |
0.00519 |
| 1.7 |
0.444 |
50.10 |
0.00313 |
0.001070 |
1.04e-03 |
0.00523 |
| 1.8 |
0.362 |
63.10 |
0.00287 |
0.001160 |
6.10e-04 |
0.00514 |
| 1.9 |
0.303 |
79.40 |
0.00275 |
0.001210 |
3.67e-04 |
0.00513 |
| 2.0 |
0.274 |
100.00 |
0.00275 |
0.001140 |
5.20e-04 |
0.00498 |
| 2.1 |
0.215 |
126.00 |
0.00275 |
0.001440 |
-7.36e-05 |
0.00557 |
| 2.2 |
0.180 |
158.00 |
0.00275 |
0.001730 |
-6.48e-04 |
0.00614 |
| 2.3 |
0.133 |
200.00 |
0.00275 |
0.002470 |
-2.10e-03 |
0.00759 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.927 |
0.00308 |
0.000729 |
0.001650 |
0.00451 |
| 0.2 |
1.58 |
0.922 |
0.00309 |
0.000733 |
0.001660 |
0.00453 |
| 0.3 |
2.00 |
0.918 |
0.00311 |
0.000736 |
0.001660 |
0.00455 |
| 0.4 |
2.51 |
0.914 |
0.00313 |
0.000741 |
0.001670 |
0.00458 |
| 0.5 |
3.16 |
0.907 |
0.00316 |
0.000750 |
0.001690 |
0.00463 |
| 0.6 |
3.98 |
0.888 |
0.00307 |
0.000746 |
0.001610 |
0.00454 |
| 0.7 |
5.01 |
0.874 |
0.00311 |
0.000755 |
0.001630 |
0.00459 |
| 0.8 |
6.31 |
0.851 |
0.00301 |
0.000751 |
0.001540 |
0.00448 |
| 0.9 |
7.94 |
0.827 |
0.00310 |
0.000773 |
0.001580 |
0.00461 |
| 1.0 |
10.00 |
0.801 |
0.00301 |
0.000774 |
0.001500 |
0.00453 |
| 1.1 |
12.60 |
0.753 |
0.00321 |
0.000826 |
0.001590 |
0.00483 |
| 1.2 |
15.80 |
0.717 |
0.00316 |
0.000838 |
0.001520 |
0.00480 |
| 1.3 |
20.00 |
0.656 |
0.00339 |
0.000905 |
0.001620 |
0.00517 |
| 1.4 |
25.10 |
0.605 |
0.00297 |
0.000875 |
0.001250 |
0.00468 |
| 1.5 |
31.60 |
0.544 |
0.00327 |
0.000973 |
0.001360 |
0.00517 |
| 1.6 |
39.80 |
0.490 |
0.00336 |
0.001050 |
0.001310 |
0.00541 |
| 1.7 |
50.10 |
0.444 |
0.00313 |
0.001070 |
0.001040 |
0.00523 |
| 1.8 |
63.10 |
0.362 |
0.00287 |
0.001160 |
0.000610 |
0.00514 |
| 1.9 |
79.40 |
0.303 |
0.00256 |
0.001210 |
0.000185 |
0.00494 |
| 2.0 |
100.00 |
0.274 |
0.00190 |
0.001140 |
-0.000328 |
0.00413 |
| 2.1 |
126.00 |
0.215 |
0.00239 |
0.001440 |
-0.000428 |
0.00521 |
| 2.2 |
158.00 |
0.180 |
0.00287 |
0.001730 |
-0.000528 |
0.00626 |
| 2.3 |
200.00 |
0.133 |
0.00401 |
0.002470 |
-0.000835 |
0.00886 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.220 |
0.214 |
-0.1990 |
0.638 |
| 0.1 |
0.927 |
1.26 |
0.323 |
0.202 |
-0.0728 |
0.718 |
| 0.2 |
0.922 |
1.58 |
0.323 |
0.202 |
-0.0740 |
0.720 |
| 0.3 |
0.918 |
2.00 |
0.323 |
0.203 |
-0.0749 |
0.721 |
| 0.4 |
0.914 |
2.51 |
0.323 |
0.204 |
-0.0767 |
0.722 |
| 0.5 |
0.907 |
3.16 |
0.323 |
0.205 |
-0.0796 |
0.725 |
| 0.6 |
0.888 |
3.98 |
0.323 |
0.205 |
-0.0785 |
0.724 |
| 0.7 |
0.874 |
5.01 |
0.323 |
0.206 |
-0.0814 |
0.727 |
| 0.8 |
0.851 |
6.31 |
0.323 |
0.206 |
-0.0800 |
0.726 |
| 0.9 |
0.827 |
7.94 |
0.323 |
0.209 |
-0.0873 |
0.733 |
| 1.0 |
0.801 |
10.00 |
0.323 |
0.209 |
-0.0876 |
0.733 |
| 1.1 |
0.753 |
12.60 |
0.323 |
0.219 |
-0.1050 |
0.751 |
| 1.2 |
0.717 |
15.80 |
0.323 |
0.221 |
-0.1100 |
0.756 |
| 1.3 |
0.656 |
20.00 |
0.323 |
0.233 |
-0.1330 |
0.779 |
| 1.4 |
0.605 |
25.10 |
0.323 |
0.227 |
-0.1230 |
0.768 |
| 1.5 |
0.544 |
31.60 |
0.323 |
0.245 |
-0.1580 |
0.803 |
| 1.6 |
0.490 |
39.80 |
0.323 |
0.259 |
-0.1850 |
0.831 |
| 1.7 |
0.444 |
50.10 |
0.323 |
0.263 |
-0.1930 |
0.839 |
| 1.8 |
0.362 |
63.10 |
0.379 |
0.275 |
-0.1610 |
0.918 |
| 1.9 |
0.303 |
79.40 |
0.406 |
0.285 |
-0.1520 |
0.964 |
| 2.0 |
0.274 |
100.00 |
0.406 |
0.269 |
-0.1220 |
0.934 |
| 2.1 |
0.215 |
126.00 |
0.406 |
0.330 |
-0.2410 |
1.050 |
| 2.2 |
0.180 |
158.00 |
0.406 |
0.390 |
-0.3590 |
1.170 |
| 2.3 |
0.133 |
200.00 |
0.406 |
0.546 |
-0.6630 |
1.480 |
IgG3_gp70.V1V2CaseA2
Monotone

| 0.0 |
1.000 |
1.00 |
0.00361 |
0.000724 |
0.002190 |
0.00503 |
| 0.1 |
0.939 |
1.26 |
0.00354 |
0.000786 |
0.002000 |
0.00507 |
| 0.2 |
0.939 |
1.58 |
0.00354 |
0.000786 |
0.002000 |
0.00507 |
| 0.3 |
0.934 |
2.00 |
0.00339 |
0.000768 |
0.001880 |
0.00489 |
| 0.4 |
0.922 |
2.51 |
0.00331 |
0.000757 |
0.001830 |
0.00480 |
| 0.5 |
0.909 |
3.16 |
0.00331 |
0.000767 |
0.001810 |
0.00482 |
| 0.6 |
0.891 |
3.98 |
0.00331 |
0.000764 |
0.001820 |
0.00481 |
| 0.7 |
0.873 |
5.01 |
0.00331 |
0.000778 |
0.001790 |
0.00484 |
| 0.8 |
0.849 |
6.31 |
0.00331 |
0.000799 |
0.001750 |
0.00488 |
| 0.9 |
0.821 |
7.94 |
0.00331 |
0.000825 |
0.001700 |
0.00493 |
| 1.0 |
0.785 |
10.00 |
0.00330 |
0.000815 |
0.001710 |
0.00490 |
| 1.1 |
0.710 |
12.60 |
0.00330 |
0.000866 |
0.001610 |
0.00500 |
| 1.2 |
0.656 |
15.80 |
0.00330 |
0.000887 |
0.001570 |
0.00504 |
| 1.3 |
0.640 |
20.00 |
0.00330 |
0.000907 |
0.001530 |
0.00508 |
| 1.4 |
0.578 |
25.10 |
0.00330 |
0.000974 |
0.001400 |
0.00521 |
| 1.5 |
0.487 |
31.60 |
0.00322 |
0.001020 |
0.001220 |
0.00522 |
| 1.6 |
0.428 |
39.80 |
0.00322 |
0.001120 |
0.001030 |
0.00541 |
| 1.7 |
0.350 |
50.10 |
0.00272 |
0.001100 |
0.000566 |
0.00488 |
| 1.8 |
0.312 |
63.10 |
0.00272 |
0.001070 |
0.000624 |
0.00483 |
| 1.9 |
0.256 |
79.40 |
0.00272 |
0.001120 |
0.000521 |
0.00493 |
| 2.0 |
0.228 |
100.00 |
0.00272 |
0.001380 |
0.000029 |
0.00542 |
| 2.1 |
0.161 |
126.00 |
0.00272 |
0.001940 |
-0.001070 |
0.00652 |
| 2.2 |
0.122 |
158.00 |
0.00272 |
0.002620 |
-0.002420 |
0.00787 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.939 |
0.00354 |
0.000786 |
0.002000 |
0.00507 |
| 0.2 |
1.58 |
0.939 |
0.00354 |
0.000786 |
0.002000 |
0.00507 |
| 0.3 |
2.00 |
0.934 |
0.00339 |
0.000768 |
0.001880 |
0.00489 |
| 0.4 |
2.51 |
0.922 |
0.00327 |
0.000757 |
0.001780 |
0.00475 |
| 0.5 |
3.16 |
0.909 |
0.00331 |
0.000767 |
0.001810 |
0.00481 |
| 0.6 |
3.98 |
0.891 |
0.00322 |
0.000764 |
0.001720 |
0.00472 |
| 0.7 |
5.01 |
0.873 |
0.00328 |
0.000778 |
0.001750 |
0.00480 |
| 0.8 |
6.31 |
0.849 |
0.00336 |
0.000799 |
0.001790 |
0.00493 |
| 0.9 |
7.94 |
0.821 |
0.00346 |
0.000825 |
0.001840 |
0.00507 |
| 1.0 |
10.00 |
0.785 |
0.00325 |
0.000815 |
0.001650 |
0.00484 |
| 1.1 |
12.60 |
0.710 |
0.00335 |
0.000866 |
0.001650 |
0.00504 |
| 1.2 |
15.80 |
0.656 |
0.00323 |
0.000887 |
0.001490 |
0.00497 |
| 1.3 |
20.00 |
0.640 |
0.00330 |
0.000907 |
0.001520 |
0.00508 |
| 1.4 |
25.10 |
0.578 |
0.00341 |
0.000974 |
0.001500 |
0.00532 |
| 1.5 |
31.60 |
0.487 |
0.00315 |
0.001020 |
0.001150 |
0.00515 |
| 1.6 |
39.80 |
0.428 |
0.00330 |
0.001120 |
0.001100 |
0.00549 |
| 1.7 |
50.10 |
0.350 |
0.00251 |
0.001100 |
0.000355 |
0.00467 |
| 1.8 |
63.10 |
0.312 |
0.00224 |
0.001070 |
0.000143 |
0.00434 |
| 1.9 |
79.40 |
0.256 |
0.00188 |
0.001120 |
-0.000326 |
0.00408 |
| 2.0 |
100.00 |
0.228 |
0.00229 |
0.001380 |
-0.000405 |
0.00499 |
| 2.1 |
126.00 |
0.161 |
0.00319 |
0.001940 |
-0.000602 |
0.00699 |
| 2.2 |
158.00 |
0.122 |
0.00423 |
0.002620 |
-0.000914 |
0.00937 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.220 |
0.214 |
-0.1990 |
0.638 |
| 0.1 |
0.939 |
1.26 |
0.236 |
0.221 |
-0.1980 |
0.670 |
| 0.2 |
0.939 |
1.58 |
0.236 |
0.221 |
-0.1980 |
0.670 |
| 0.3 |
0.934 |
2.00 |
0.268 |
0.215 |
-0.1530 |
0.689 |
| 0.4 |
0.922 |
2.51 |
0.284 |
0.211 |
-0.1300 |
0.698 |
| 0.5 |
0.909 |
3.16 |
0.284 |
0.213 |
-0.1330 |
0.701 |
| 0.6 |
0.891 |
3.98 |
0.284 |
0.212 |
-0.1320 |
0.700 |
| 0.7 |
0.873 |
5.01 |
0.284 |
0.215 |
-0.1370 |
0.705 |
| 0.8 |
0.849 |
6.31 |
0.284 |
0.218 |
-0.1440 |
0.712 |
| 0.9 |
0.821 |
7.94 |
0.284 |
0.223 |
-0.1520 |
0.720 |
| 1.0 |
0.785 |
10.00 |
0.286 |
0.221 |
-0.1470 |
0.718 |
| 1.1 |
0.710 |
12.60 |
0.286 |
0.230 |
-0.1640 |
0.736 |
| 1.2 |
0.656 |
15.80 |
0.286 |
0.233 |
-0.1710 |
0.743 |
| 1.3 |
0.640 |
20.00 |
0.286 |
0.237 |
-0.1780 |
0.750 |
| 1.4 |
0.578 |
25.10 |
0.286 |
0.249 |
-0.2020 |
0.774 |
| 1.5 |
0.487 |
31.60 |
0.304 |
0.255 |
-0.1970 |
0.805 |
| 1.6 |
0.428 |
39.80 |
0.304 |
0.274 |
-0.2330 |
0.842 |
| 1.7 |
0.350 |
50.10 |
0.411 |
0.262 |
-0.1020 |
0.925 |
| 1.8 |
0.312 |
63.10 |
0.411 |
0.256 |
-0.0911 |
0.913 |
| 1.9 |
0.256 |
79.40 |
0.411 |
0.267 |
-0.1110 |
0.934 |
| 2.0 |
0.228 |
100.00 |
0.411 |
0.317 |
-0.2100 |
1.030 |
| 2.1 |
0.161 |
126.00 |
0.411 |
0.432 |
-0.4360 |
1.260 |
| 2.2 |
0.122 |
158.00 |
0.411 |
0.578 |
-0.7210 |
1.540 |
IgG3_gp70BCaseA2V1V2169K
Monotone

| 0.0 |
1.000 |
1.00 |
0.00361 |
0.000724 |
0.002190 |
0.00503 |
| 0.1 |
0.966 |
1.26 |
0.00330 |
0.000741 |
0.001840 |
0.00475 |
| 0.2 |
0.966 |
1.58 |
0.00330 |
0.000741 |
0.001840 |
0.00475 |
| 0.3 |
0.966 |
2.00 |
0.00330 |
0.000741 |
0.001840 |
0.00475 |
| 0.4 |
0.966 |
2.51 |
0.00330 |
0.000741 |
0.001840 |
0.00475 |
| 0.5 |
0.964 |
3.16 |
0.00330 |
0.000742 |
0.001840 |
0.00475 |
| 0.6 |
0.960 |
3.98 |
0.00330 |
0.000744 |
0.001840 |
0.00475 |
| 0.7 |
0.955 |
5.01 |
0.00330 |
0.000748 |
0.001830 |
0.00476 |
| 0.8 |
0.932 |
6.31 |
0.00330 |
0.000767 |
0.001790 |
0.00480 |
| 0.9 |
0.910 |
7.94 |
0.00330 |
0.000764 |
0.001800 |
0.00479 |
| 1.0 |
0.902 |
10.00 |
0.00330 |
0.000769 |
0.001790 |
0.00480 |
| 1.1 |
0.889 |
12.60 |
0.00321 |
0.000755 |
0.001730 |
0.00469 |
| 1.2 |
0.874 |
15.80 |
0.00321 |
0.000769 |
0.001700 |
0.00471 |
| 1.3 |
0.850 |
20.00 |
0.00321 |
0.000767 |
0.001710 |
0.00471 |
| 1.4 |
0.825 |
25.10 |
0.00321 |
0.000788 |
0.001660 |
0.00475 |
| 1.5 |
0.776 |
31.60 |
0.00321 |
0.000806 |
0.001630 |
0.00479 |
| 1.6 |
0.740 |
39.80 |
0.00321 |
0.000795 |
0.001650 |
0.00477 |
| 1.7 |
0.687 |
50.10 |
0.00321 |
0.000861 |
0.001520 |
0.00489 |
| 1.8 |
0.644 |
63.10 |
0.00321 |
0.000897 |
0.001450 |
0.00497 |
| 1.9 |
0.608 |
79.40 |
0.00321 |
0.000887 |
0.001470 |
0.00495 |
| 2.0 |
0.530 |
100.00 |
0.00321 |
0.000983 |
0.001280 |
0.00513 |
| 2.1 |
0.457 |
126.00 |
0.00321 |
0.001140 |
0.000980 |
0.00544 |
| 2.2 |
0.379 |
158.00 |
0.00321 |
0.001170 |
0.000911 |
0.00550 |
| 2.3 |
0.325 |
200.00 |
0.00321 |
0.001180 |
0.000889 |
0.00553 |
| 2.4 |
0.278 |
251.00 |
0.00321 |
0.001340 |
0.000588 |
0.00583 |
| 2.5 |
0.218 |
316.00 |
0.00321 |
0.001470 |
0.000320 |
0.00610 |
| 2.6 |
0.168 |
398.00 |
0.00321 |
0.001900 |
-0.000508 |
0.00692 |
| 2.7 |
0.127 |
501.00 |
0.00321 |
0.002630 |
-0.001950 |
0.00837 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.966 |
0.00327 |
0.000741 |
0.001820 |
0.00473 |
| 0.2 |
1.58 |
0.966 |
0.00327 |
0.000741 |
0.001820 |
0.00473 |
| 0.3 |
2.00 |
0.966 |
0.00327 |
0.000741 |
0.001820 |
0.00473 |
| 0.4 |
2.51 |
0.966 |
0.00327 |
0.000741 |
0.001820 |
0.00473 |
| 0.5 |
3.16 |
0.964 |
0.00328 |
0.000742 |
0.001820 |
0.00473 |
| 0.6 |
3.98 |
0.960 |
0.00329 |
0.000744 |
0.001830 |
0.00474 |
| 0.7 |
5.01 |
0.955 |
0.00331 |
0.000748 |
0.001840 |
0.00477 |
| 0.8 |
6.31 |
0.932 |
0.00338 |
0.000767 |
0.001880 |
0.00489 |
| 0.9 |
7.94 |
0.910 |
0.00330 |
0.000764 |
0.001800 |
0.00480 |
| 1.0 |
10.00 |
0.902 |
0.00332 |
0.000769 |
0.001810 |
0.00482 |
| 1.1 |
12.60 |
0.889 |
0.00318 |
0.000755 |
0.001700 |
0.00466 |
| 1.2 |
15.80 |
0.874 |
0.00324 |
0.000769 |
0.001730 |
0.00474 |
| 1.3 |
20.00 |
0.850 |
0.00315 |
0.000767 |
0.001650 |
0.00465 |
| 1.4 |
25.10 |
0.825 |
0.00323 |
0.000788 |
0.001690 |
0.00478 |
| 1.5 |
31.60 |
0.776 |
0.00321 |
0.000806 |
0.001630 |
0.00479 |
| 1.6 |
39.80 |
0.740 |
0.00299 |
0.000795 |
0.001430 |
0.00455 |
| 1.7 |
50.10 |
0.687 |
0.00323 |
0.000861 |
0.001540 |
0.00491 |
| 1.8 |
63.10 |
0.644 |
0.00326 |
0.000897 |
0.001510 |
0.00502 |
| 1.9 |
79.40 |
0.608 |
0.00301 |
0.000887 |
0.001270 |
0.00475 |
| 2.0 |
100.00 |
0.530 |
0.00319 |
0.000983 |
0.001270 |
0.00512 |
| 2.1 |
126.00 |
0.457 |
0.00367 |
0.001140 |
0.001440 |
0.00589 |
| 2.2 |
158.00 |
0.379 |
0.00312 |
0.001170 |
0.000819 |
0.00541 |
| 2.3 |
200.00 |
0.325 |
0.00274 |
0.001180 |
0.000422 |
0.00506 |
| 2.4 |
251.00 |
0.278 |
0.00279 |
0.001340 |
0.000166 |
0.00541 |
| 2.5 |
316.00 |
0.218 |
0.00273 |
0.001470 |
-0.000161 |
0.00562 |
| 2.6 |
398.00 |
0.168 |
0.00349 |
0.001900 |
-0.000223 |
0.00721 |
| 2.7 |
501.00 |
0.127 |
0.00466 |
0.002630 |
-0.000500 |
0.00981 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.220 |
0.214 |
-0.199 |
0.638 |
| 0.1 |
0.966 |
1.26 |
0.288 |
0.208 |
-0.120 |
0.695 |
| 0.2 |
0.966 |
1.58 |
0.288 |
0.208 |
-0.120 |
0.695 |
| 0.3 |
0.966 |
2.00 |
0.288 |
0.208 |
-0.120 |
0.695 |
| 0.4 |
0.966 |
2.51 |
0.288 |
0.208 |
-0.120 |
0.695 |
| 0.5 |
0.964 |
3.16 |
0.288 |
0.208 |
-0.120 |
0.695 |
| 0.6 |
0.960 |
3.98 |
0.288 |
0.208 |
-0.121 |
0.696 |
| 0.7 |
0.955 |
5.01 |
0.288 |
0.209 |
-0.122 |
0.698 |
| 0.8 |
0.932 |
6.31 |
0.288 |
0.212 |
-0.128 |
0.704 |
| 0.9 |
0.910 |
7.94 |
0.288 |
0.212 |
-0.128 |
0.703 |
| 1.0 |
0.902 |
10.00 |
0.288 |
0.213 |
-0.129 |
0.704 |
| 1.1 |
0.889 |
12.60 |
0.307 |
0.208 |
-0.101 |
0.714 |
| 1.2 |
0.874 |
15.80 |
0.307 |
0.210 |
-0.106 |
0.719 |
| 1.3 |
0.850 |
20.00 |
0.307 |
0.210 |
-0.105 |
0.718 |
| 1.4 |
0.825 |
25.10 |
0.307 |
0.214 |
-0.112 |
0.726 |
| 1.5 |
0.776 |
31.60 |
0.307 |
0.217 |
-0.118 |
0.732 |
| 1.6 |
0.740 |
39.80 |
0.307 |
0.215 |
-0.114 |
0.728 |
| 1.7 |
0.687 |
50.10 |
0.307 |
0.226 |
-0.137 |
0.750 |
| 1.8 |
0.644 |
63.10 |
0.307 |
0.233 |
-0.150 |
0.763 |
| 1.9 |
0.608 |
79.40 |
0.307 |
0.231 |
-0.146 |
0.760 |
| 2.0 |
0.530 |
100.00 |
0.307 |
0.249 |
-0.180 |
0.794 |
| 2.1 |
0.457 |
126.00 |
0.307 |
0.277 |
-0.237 |
0.851 |
| 2.2 |
0.379 |
158.00 |
0.307 |
0.284 |
-0.250 |
0.864 |
| 2.3 |
0.325 |
200.00 |
0.307 |
0.286 |
-0.255 |
0.868 |
| 2.4 |
0.278 |
251.00 |
0.307 |
0.316 |
-0.313 |
0.927 |
| 2.5 |
0.218 |
316.00 |
0.307 |
0.344 |
-0.367 |
0.980 |
| 2.6 |
0.168 |
398.00 |
0.307 |
0.430 |
-0.535 |
1.150 |
| 2.7 |
0.127 |
501.00 |
0.307 |
0.583 |
-0.836 |
1.450 |
IgG3_gp70BCaseA2V1V2mut3
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00361 |
0.000724 |
2.19e-03 |
0.00503 |
| 0.1 |
0.9830 |
1.26 |
0.00355 |
0.000766 |
2.04e-03 |
0.00505 |
| 0.2 |
0.9830 |
1.58 |
0.00355 |
0.000766 |
2.04e-03 |
0.00505 |
| 0.3 |
0.9830 |
2.00 |
0.00355 |
0.000766 |
2.04e-03 |
0.00505 |
| 0.4 |
0.9830 |
2.51 |
0.00355 |
0.000766 |
2.04e-03 |
0.00505 |
| 0.5 |
0.9810 |
3.16 |
0.00355 |
0.000767 |
2.04e-03 |
0.00505 |
| 0.6 |
0.9810 |
3.98 |
0.00355 |
0.000767 |
2.04e-03 |
0.00505 |
| 0.7 |
0.9770 |
5.01 |
0.00355 |
0.000770 |
2.04e-03 |
0.00505 |
| 0.8 |
0.9770 |
6.31 |
0.00355 |
0.000770 |
2.04e-03 |
0.00505 |
| 0.9 |
0.9730 |
7.94 |
0.00355 |
0.000772 |
2.03e-03 |
0.00506 |
| 1.0 |
0.9730 |
10.00 |
0.00355 |
0.000772 |
2.03e-03 |
0.00506 |
| 1.1 |
0.9660 |
12.60 |
0.00355 |
0.000776 |
2.02e-03 |
0.00507 |
| 1.2 |
0.9660 |
15.80 |
0.00355 |
0.000776 |
2.02e-03 |
0.00507 |
| 1.3 |
0.9660 |
20.00 |
0.00355 |
0.000776 |
2.02e-03 |
0.00507 |
| 1.4 |
0.9570 |
25.10 |
0.00355 |
0.000783 |
2.01e-03 |
0.00508 |
| 1.5 |
0.9530 |
31.60 |
0.00355 |
0.000786 |
2.00e-03 |
0.00509 |
| 1.6 |
0.9490 |
39.80 |
0.00336 |
0.000752 |
1.89e-03 |
0.00484 |
| 1.7 |
0.9490 |
50.10 |
0.00336 |
0.000752 |
1.89e-03 |
0.00484 |
| 1.8 |
0.9390 |
63.10 |
0.00336 |
0.000760 |
1.87e-03 |
0.00485 |
| 1.9 |
0.9250 |
79.40 |
0.00336 |
0.000769 |
1.85e-03 |
0.00487 |
| 2.0 |
0.9110 |
100.00 |
0.00336 |
0.000761 |
1.87e-03 |
0.00485 |
| 2.1 |
0.8890 |
126.00 |
0.00336 |
0.000783 |
1.83e-03 |
0.00490 |
| 2.2 |
0.8700 |
158.00 |
0.00336 |
0.000778 |
1.84e-03 |
0.00489 |
| 2.3 |
0.8460 |
200.00 |
0.00336 |
0.000778 |
1.84e-03 |
0.00489 |
| 2.4 |
0.8320 |
251.00 |
0.00336 |
0.000791 |
1.81e-03 |
0.00491 |
| 2.5 |
0.8110 |
316.00 |
0.00336 |
0.000787 |
1.82e-03 |
0.00490 |
| 2.6 |
0.7360 |
398.00 |
0.00336 |
0.000790 |
1.81e-03 |
0.00491 |
| 2.7 |
0.6820 |
501.00 |
0.00336 |
0.000855 |
1.69e-03 |
0.00504 |
| 2.8 |
0.6280 |
631.00 |
0.00336 |
0.000905 |
1.59e-03 |
0.00513 |
| 2.9 |
0.5600 |
794.00 |
0.00336 |
0.001020 |
1.37e-03 |
0.00536 |
| 3.0 |
0.4840 |
1000.00 |
0.00336 |
0.001120 |
1.17e-03 |
0.00555 |
| 3.1 |
0.4250 |
1260.00 |
0.00336 |
0.001240 |
9.24e-04 |
0.00580 |
| 3.2 |
0.3220 |
1580.00 |
0.00336 |
0.001600 |
2.17e-04 |
0.00650 |
| 3.3 |
0.2660 |
2000.00 |
0.00336 |
0.001730 |
-2.66e-05 |
0.00675 |
| 3.4 |
0.2400 |
2510.00 |
0.00336 |
0.001930 |
-4.15e-04 |
0.00714 |
| 3.5 |
0.1780 |
3160.00 |
0.00336 |
0.002360 |
-1.27e-03 |
0.00800 |
| 3.6 |
0.1400 |
3980.00 |
0.00336 |
0.002990 |
-2.50e-03 |
0.00922 |
| 3.7 |
0.0991 |
5010.00 |
0.00336 |
0.004080 |
-4.63e-03 |
0.01140 |
| 3.8 |
0.0738 |
6310.00 |
0.00336 |
0.005050 |
-6.53e-03 |
0.01330 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00361 |
0.000724 |
0.002100 |
0.00513 |
| 0.1 |
1.26 |
0.9830 |
0.00352 |
0.000766 |
0.002020 |
0.00502 |
| 0.2 |
1.58 |
0.9830 |
0.00352 |
0.000766 |
0.002020 |
0.00502 |
| 0.3 |
2.00 |
0.9830 |
0.00352 |
0.000766 |
0.002020 |
0.00502 |
| 0.4 |
2.51 |
0.9830 |
0.00352 |
0.000766 |
0.002020 |
0.00502 |
| 0.5 |
3.16 |
0.9810 |
0.00352 |
0.000767 |
0.002020 |
0.00502 |
| 0.6 |
3.98 |
0.9810 |
0.00352 |
0.000767 |
0.002020 |
0.00502 |
| 0.7 |
5.01 |
0.9770 |
0.00354 |
0.000770 |
0.002030 |
0.00505 |
| 0.8 |
6.31 |
0.9770 |
0.00354 |
0.000770 |
0.002030 |
0.00505 |
| 0.9 |
7.94 |
0.9730 |
0.00355 |
0.000772 |
0.002030 |
0.00506 |
| 1.0 |
10.00 |
0.9730 |
0.00355 |
0.000772 |
0.002030 |
0.00506 |
| 1.1 |
12.60 |
0.9660 |
0.00356 |
0.000776 |
0.002040 |
0.00508 |
| 1.2 |
15.80 |
0.9660 |
0.00356 |
0.000776 |
0.002040 |
0.00508 |
| 1.3 |
20.00 |
0.9660 |
0.00356 |
0.000776 |
0.002040 |
0.00508 |
| 1.4 |
25.10 |
0.9570 |
0.00360 |
0.000783 |
0.002060 |
0.00513 |
| 1.5 |
31.60 |
0.9530 |
0.00361 |
0.000786 |
0.002070 |
0.00515 |
| 1.6 |
39.80 |
0.9490 |
0.00332 |
0.000752 |
0.001850 |
0.00480 |
| 1.7 |
50.10 |
0.9490 |
0.00332 |
0.000752 |
0.001850 |
0.00480 |
| 1.8 |
63.10 |
0.9390 |
0.00336 |
0.000760 |
0.001870 |
0.00485 |
| 1.9 |
79.40 |
0.9250 |
0.00340 |
0.000769 |
0.001890 |
0.00490 |
| 2.0 |
100.00 |
0.9110 |
0.00329 |
0.000761 |
0.001790 |
0.00478 |
| 2.1 |
126.00 |
0.8890 |
0.00337 |
0.000783 |
0.001840 |
0.00491 |
| 2.2 |
158.00 |
0.8700 |
0.00328 |
0.000778 |
0.001750 |
0.00480 |
| 2.3 |
200.00 |
0.8460 |
0.00319 |
0.000778 |
0.001670 |
0.00472 |
| 2.4 |
251.00 |
0.8320 |
0.00324 |
0.000791 |
0.001690 |
0.00480 |
| 2.5 |
316.00 |
0.8110 |
0.00314 |
0.000787 |
0.001600 |
0.00468 |
| 2.6 |
398.00 |
0.7360 |
0.00288 |
0.000790 |
0.001330 |
0.00443 |
| 2.7 |
501.00 |
0.6820 |
0.00311 |
0.000855 |
0.001440 |
0.00479 |
| 2.8 |
631.00 |
0.6280 |
0.00318 |
0.000905 |
0.001410 |
0.00496 |
| 2.9 |
794.00 |
0.5600 |
0.00356 |
0.001020 |
0.001560 |
0.00555 |
| 3.0 |
1000.00 |
0.4840 |
0.00362 |
0.001120 |
0.001420 |
0.00581 |
| 3.1 |
1260.00 |
0.4250 |
0.00384 |
0.001240 |
0.001400 |
0.00628 |
| 3.2 |
1580.00 |
0.3220 |
0.00466 |
0.001600 |
0.001510 |
0.00780 |
| 3.3 |
2000.00 |
0.2660 |
0.00445 |
0.001730 |
0.001060 |
0.00784 |
| 3.4 |
2510.00 |
0.2400 |
0.00459 |
0.001930 |
0.000814 |
0.00837 |
| 3.5 |
3160.00 |
0.1780 |
0.00524 |
0.002360 |
0.000602 |
0.00987 |
| 3.6 |
3980.00 |
0.1400 |
0.00603 |
0.002990 |
0.000172 |
0.01190 |
| 3.7 |
5010.00 |
0.0991 |
0.00709 |
0.004080 |
-0.000909 |
0.01510 |
| 3.8 |
6310.00 |
0.0738 |
0.00872 |
0.005050 |
-0.001170 |
0.01860 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.220 |
0.214 |
-0.199 |
0.638 |
| 0.1 |
0.9830 |
1.26 |
0.234 |
0.218 |
-0.194 |
0.662 |
| 0.2 |
0.9830 |
1.58 |
0.234 |
0.218 |
-0.194 |
0.662 |
| 0.3 |
0.9830 |
2.00 |
0.234 |
0.218 |
-0.194 |
0.662 |
| 0.4 |
0.9830 |
2.51 |
0.234 |
0.218 |
-0.194 |
0.662 |
| 0.5 |
0.9810 |
3.16 |
0.234 |
0.219 |
-0.195 |
0.662 |
| 0.6 |
0.9810 |
3.98 |
0.234 |
0.219 |
-0.195 |
0.662 |
| 0.7 |
0.9770 |
5.01 |
0.234 |
0.219 |
-0.196 |
0.663 |
| 0.8 |
0.9770 |
6.31 |
0.234 |
0.219 |
-0.196 |
0.663 |
| 0.9 |
0.9730 |
7.94 |
0.234 |
0.219 |
-0.196 |
0.664 |
| 1.0 |
0.9730 |
10.00 |
0.234 |
0.219 |
-0.196 |
0.664 |
| 1.1 |
0.9660 |
12.60 |
0.234 |
0.220 |
-0.198 |
0.665 |
| 1.2 |
0.9660 |
15.80 |
0.234 |
0.220 |
-0.198 |
0.665 |
| 1.3 |
0.9660 |
20.00 |
0.234 |
0.220 |
-0.198 |
0.665 |
| 1.4 |
0.9570 |
25.10 |
0.234 |
0.221 |
-0.200 |
0.668 |
| 1.5 |
0.9530 |
31.60 |
0.234 |
0.222 |
-0.201 |
0.669 |
| 1.6 |
0.9490 |
39.80 |
0.274 |
0.211 |
-0.141 |
0.688 |
| 1.7 |
0.9490 |
50.10 |
0.274 |
0.211 |
-0.141 |
0.688 |
| 1.8 |
0.9390 |
63.10 |
0.274 |
0.213 |
-0.143 |
0.691 |
| 1.9 |
0.9250 |
79.40 |
0.274 |
0.214 |
-0.146 |
0.694 |
| 2.0 |
0.9110 |
100.00 |
0.274 |
0.213 |
-0.144 |
0.691 |
| 2.1 |
0.8890 |
126.00 |
0.274 |
0.217 |
-0.151 |
0.698 |
| 2.2 |
0.8700 |
158.00 |
0.274 |
0.216 |
-0.149 |
0.697 |
| 2.3 |
0.8460 |
200.00 |
0.274 |
0.216 |
-0.149 |
0.697 |
| 2.4 |
0.8320 |
251.00 |
0.274 |
0.218 |
-0.154 |
0.701 |
| 2.5 |
0.8110 |
316.00 |
0.274 |
0.217 |
-0.152 |
0.700 |
| 2.6 |
0.7360 |
398.00 |
0.274 |
0.218 |
-0.153 |
0.701 |
| 2.7 |
0.6820 |
501.00 |
0.274 |
0.229 |
-0.175 |
0.722 |
| 2.8 |
0.6280 |
631.00 |
0.274 |
0.238 |
-0.192 |
0.740 |
| 2.9 |
0.5600 |
794.00 |
0.274 |
0.258 |
-0.232 |
0.780 |
| 3.0 |
0.4840 |
1000.00 |
0.274 |
0.277 |
-0.269 |
0.817 |
| 3.1 |
0.4250 |
1260.00 |
0.274 |
0.301 |
-0.316 |
0.863 |
| 3.2 |
0.3220 |
1580.00 |
0.274 |
0.372 |
-0.456 |
1.000 |
| 3.3 |
0.2660 |
2000.00 |
0.274 |
0.397 |
-0.505 |
1.050 |
| 3.4 |
0.2400 |
2510.00 |
0.274 |
0.438 |
-0.584 |
1.130 |
| 3.5 |
0.1780 |
3160.00 |
0.274 |
0.529 |
-0.762 |
1.310 |
| 3.6 |
0.1400 |
3980.00 |
0.274 |
0.660 |
-1.020 |
1.570 |
| 3.7 |
0.0991 |
5010.00 |
0.274 |
0.892 |
-1.470 |
2.020 |
| 3.8 |
0.0738 |
6310.00 |
0.274 |
1.100 |
-1.880 |
2.430 |
IgG_PE_BioRV144_V2_AE
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00361 |
0.000724 |
0.002190 |
0.00503 |
| 0.1 |
0.9740 |
1.26 |
0.00329 |
0.000743 |
0.001830 |
0.00474 |
| 0.2 |
0.9740 |
1.58 |
0.00316 |
0.000725 |
0.001740 |
0.00458 |
| 0.3 |
0.9740 |
2.00 |
0.00316 |
0.000725 |
0.001740 |
0.00458 |
| 0.4 |
0.9740 |
2.51 |
0.00316 |
0.000725 |
0.001740 |
0.00458 |
| 0.5 |
0.9740 |
3.16 |
0.00316 |
0.000725 |
0.001740 |
0.00458 |
| 0.6 |
0.9740 |
3.98 |
0.00316 |
0.000725 |
0.001740 |
0.00458 |
| 0.7 |
0.9670 |
5.01 |
0.00316 |
0.000727 |
0.001740 |
0.00459 |
| 0.8 |
0.9660 |
6.31 |
0.00316 |
0.000728 |
0.001740 |
0.00459 |
| 0.9 |
0.9530 |
7.94 |
0.00316 |
0.000739 |
0.001710 |
0.00461 |
| 1.0 |
0.9520 |
10.00 |
0.00316 |
0.000740 |
0.001710 |
0.00461 |
| 1.1 |
0.9320 |
12.60 |
0.00316 |
0.000752 |
0.001690 |
0.00464 |
| 1.2 |
0.9090 |
15.80 |
0.00316 |
0.000748 |
0.001690 |
0.00462 |
| 1.3 |
0.8990 |
20.00 |
0.00302 |
0.000733 |
0.001580 |
0.00446 |
| 1.4 |
0.8760 |
25.10 |
0.00279 |
0.000714 |
0.001390 |
0.00419 |
| 1.5 |
0.8390 |
31.60 |
0.00276 |
0.000715 |
0.001360 |
0.00416 |
| 1.6 |
0.8090 |
39.80 |
0.00276 |
0.000739 |
0.001310 |
0.00421 |
| 1.7 |
0.7800 |
50.10 |
0.00269 |
0.000733 |
0.001250 |
0.00412 |
| 1.8 |
0.7130 |
63.10 |
0.00232 |
0.000706 |
0.000939 |
0.00371 |
| 1.9 |
0.6660 |
79.40 |
0.00230 |
0.000729 |
0.000870 |
0.00373 |
| 2.0 |
0.6130 |
100.00 |
0.00230 |
0.000675 |
0.000976 |
0.00362 |
| 2.1 |
0.5840 |
126.00 |
0.00230 |
0.000644 |
0.001040 |
0.00356 |
| 2.2 |
0.4970 |
158.00 |
0.00230 |
0.000761 |
0.000808 |
0.00379 |
| 2.3 |
0.4330 |
200.00 |
0.00230 |
0.000882 |
0.000572 |
0.00403 |
| 2.4 |
0.3770 |
251.00 |
0.00230 |
0.001030 |
0.000290 |
0.00431 |
| 2.5 |
0.3120 |
316.00 |
0.00230 |
0.000987 |
0.000365 |
0.00423 |
| 2.6 |
0.2590 |
398.00 |
0.00230 |
0.000859 |
0.000615 |
0.00398 |
| 2.7 |
0.2180 |
501.00 |
0.00230 |
0.000959 |
0.000420 |
0.00418 |
| 2.8 |
0.1770 |
631.00 |
0.00230 |
0.001270 |
-0.000192 |
0.00479 |
| 2.9 |
0.1390 |
794.00 |
0.00230 |
0.001510 |
-0.000657 |
0.00526 |
| 3.0 |
0.1030 |
1000.00 |
0.00230 |
0.001930 |
-0.001480 |
0.00608 |
| 3.1 |
0.0622 |
1260.00 |
0.00230 |
0.003730 |
-0.005010 |
0.00961 |
| 3.2 |
0.0568 |
1580.00 |
0.00230 |
0.004040 |
-0.005620 |
0.01020 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00361 |
0.000724 |
0.002000 |
0.00499 |
| 0.1 |
1.26 |
0.9740 |
0.00329 |
0.000743 |
0.001830 |
0.00474 |
| 0.2 |
1.58 |
0.9740 |
0.00314 |
0.000725 |
0.001720 |
0.00456 |
| 0.3 |
2.00 |
0.9740 |
0.00314 |
0.000725 |
0.001720 |
0.00456 |
| 0.4 |
2.51 |
0.9740 |
0.00314 |
0.000725 |
0.001720 |
0.00456 |
| 0.5 |
3.16 |
0.9740 |
0.00314 |
0.000725 |
0.001720 |
0.00456 |
| 0.6 |
3.98 |
0.9740 |
0.00314 |
0.000725 |
0.001720 |
0.00456 |
| 0.7 |
5.01 |
0.9670 |
0.00315 |
0.000727 |
0.001720 |
0.00457 |
| 0.8 |
6.31 |
0.9660 |
0.00315 |
0.000728 |
0.001720 |
0.00458 |
| 0.9 |
7.94 |
0.9530 |
0.00320 |
0.000739 |
0.001750 |
0.00465 |
| 1.0 |
10.00 |
0.9520 |
0.00320 |
0.000740 |
0.001750 |
0.00465 |
| 1.1 |
12.60 |
0.9320 |
0.00325 |
0.000752 |
0.001780 |
0.00473 |
| 1.2 |
15.80 |
0.9090 |
0.00316 |
0.000748 |
0.001690 |
0.00462 |
| 1.3 |
20.00 |
0.8990 |
0.00302 |
0.000733 |
0.001580 |
0.00446 |
| 1.4 |
25.10 |
0.8760 |
0.00279 |
0.000714 |
0.001390 |
0.00419 |
| 1.5 |
31.60 |
0.8390 |
0.00271 |
0.000715 |
0.001310 |
0.00411 |
| 1.6 |
39.80 |
0.8090 |
0.00280 |
0.000739 |
0.001350 |
0.00425 |
| 1.7 |
50.10 |
0.7800 |
0.00269 |
0.000733 |
0.001250 |
0.00412 |
| 1.8 |
63.10 |
0.7130 |
0.00232 |
0.000706 |
0.000939 |
0.00371 |
| 1.9 |
79.40 |
0.6660 |
0.00230 |
0.000729 |
0.000866 |
0.00373 |
| 2.0 |
100.00 |
0.6130 |
0.00193 |
0.000675 |
0.000606 |
0.00325 |
| 2.1 |
126.00 |
0.5840 |
0.00174 |
0.000644 |
0.000476 |
0.00300 |
| 2.2 |
158.00 |
0.4970 |
0.00191 |
0.000761 |
0.000419 |
0.00340 |
| 2.3 |
200.00 |
0.4330 |
0.00221 |
0.000882 |
0.000483 |
0.00394 |
| 2.4 |
251.00 |
0.3770 |
0.00255 |
0.001030 |
0.000541 |
0.00456 |
| 2.5 |
316.00 |
0.3120 |
0.00207 |
0.000987 |
0.000139 |
0.00401 |
| 2.6 |
398.00 |
0.2590 |
0.00143 |
0.000859 |
-0.000259 |
0.00311 |
| 2.7 |
501.00 |
0.2180 |
0.00155 |
0.000959 |
-0.000329 |
0.00343 |
| 2.8 |
631.00 |
0.1770 |
0.00205 |
0.001270 |
-0.000442 |
0.00454 |
| 2.9 |
794.00 |
0.1390 |
0.00247 |
0.001510 |
-0.000489 |
0.00542 |
| 3.0 |
1000.00 |
0.1030 |
0.00310 |
0.001930 |
-0.000679 |
0.00689 |
| 3.1 |
1260.00 |
0.0622 |
0.00555 |
0.003730 |
-0.001760 |
0.01290 |
| 3.2 |
1580.00 |
0.0568 |
0.00630 |
0.004040 |
-0.001620 |
0.01420 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.220 |
0.214 |
-0.1990 |
0.638 |
| 0.1 |
0.9740 |
1.26 |
0.290 |
0.208 |
-0.1180 |
0.698 |
| 0.2 |
0.9740 |
1.58 |
0.316 |
0.202 |
-0.0793 |
0.712 |
| 0.3 |
0.9740 |
2.00 |
0.316 |
0.202 |
-0.0793 |
0.712 |
| 0.4 |
0.9740 |
2.51 |
0.316 |
0.202 |
-0.0793 |
0.712 |
| 0.5 |
0.9740 |
3.16 |
0.316 |
0.202 |
-0.0793 |
0.712 |
| 0.6 |
0.9740 |
3.98 |
0.316 |
0.202 |
-0.0793 |
0.712 |
| 0.7 |
0.9670 |
5.01 |
0.316 |
0.202 |
-0.0802 |
0.713 |
| 0.8 |
0.9660 |
6.31 |
0.316 |
0.202 |
-0.0804 |
0.713 |
| 0.9 |
0.9530 |
7.94 |
0.316 |
0.204 |
-0.0842 |
0.717 |
| 1.0 |
0.9520 |
10.00 |
0.316 |
0.204 |
-0.0845 |
0.717 |
| 1.1 |
0.9320 |
12.60 |
0.316 |
0.207 |
-0.0885 |
0.721 |
| 1.2 |
0.9090 |
15.80 |
0.318 |
0.205 |
-0.0848 |
0.721 |
| 1.3 |
0.8990 |
20.00 |
0.347 |
0.200 |
-0.0440 |
0.739 |
| 1.4 |
0.8760 |
25.10 |
0.397 |
0.191 |
0.0227 |
0.771 |
| 1.5 |
0.8390 |
31.60 |
0.404 |
0.190 |
0.0316 |
0.777 |
| 1.6 |
0.8090 |
39.80 |
0.404 |
0.194 |
0.0232 |
0.786 |
| 1.7 |
0.7800 |
50.10 |
0.419 |
0.192 |
0.0431 |
0.795 |
| 1.8 |
0.7130 |
63.10 |
0.498 |
0.179 |
0.1480 |
0.849 |
| 1.9 |
0.6660 |
79.40 |
0.503 |
0.183 |
0.1450 |
0.861 |
| 2.0 |
0.6130 |
100.00 |
0.503 |
0.173 |
0.1640 |
0.842 |
| 2.1 |
0.5840 |
126.00 |
0.503 |
0.167 |
0.1750 |
0.831 |
| 2.2 |
0.4970 |
158.00 |
0.503 |
0.189 |
0.1330 |
0.873 |
| 2.3 |
0.4330 |
200.00 |
0.503 |
0.212 |
0.0879 |
0.918 |
| 2.4 |
0.3770 |
251.00 |
0.503 |
0.240 |
0.0324 |
0.974 |
| 2.5 |
0.3120 |
316.00 |
0.503 |
0.233 |
0.0472 |
0.959 |
| 2.6 |
0.2590 |
398.00 |
0.503 |
0.207 |
0.0964 |
0.910 |
| 2.7 |
0.2180 |
501.00 |
0.503 |
0.227 |
0.0581 |
0.948 |
| 2.8 |
0.1770 |
631.00 |
0.503 |
0.290 |
-0.0652 |
1.070 |
| 2.9 |
0.1390 |
794.00 |
0.503 |
0.339 |
-0.1610 |
1.170 |
| 3.0 |
0.1030 |
1000.00 |
0.503 |
0.427 |
-0.3350 |
1.340 |
| 3.1 |
0.0622 |
1260.00 |
0.503 |
0.811 |
-1.0900 |
2.090 |
| 3.2 |
0.0568 |
1580.00 |
0.503 |
0.878 |
-1.2200 |
2.220 |
IgG_PE_BioRV144_V2_B
Monotone

| 0.0 |
1.000 |
1.00 |
0.00384 |
0.000724 |
0.002420 |
0.00526 |
| 0.1 |
0.842 |
1.26 |
0.00384 |
0.000854 |
0.002170 |
0.00552 |
| 0.2 |
0.838 |
1.58 |
0.00384 |
0.000858 |
0.002160 |
0.00553 |
| 0.3 |
0.828 |
2.00 |
0.00384 |
0.000871 |
0.002140 |
0.00555 |
| 0.4 |
0.790 |
2.51 |
0.00384 |
0.000921 |
0.002040 |
0.00565 |
| 0.5 |
0.774 |
3.16 |
0.00384 |
0.000940 |
0.002000 |
0.00569 |
| 0.6 |
0.769 |
3.98 |
0.00384 |
0.000945 |
0.001990 |
0.00570 |
| 0.7 |
0.755 |
5.01 |
0.00384 |
0.000938 |
0.002010 |
0.00568 |
| 0.8 |
0.717 |
6.31 |
0.00384 |
0.000963 |
0.001960 |
0.00573 |
| 0.9 |
0.698 |
7.94 |
0.00384 |
0.000990 |
0.001900 |
0.00578 |
| 1.0 |
0.685 |
10.00 |
0.00384 |
0.000978 |
0.001930 |
0.00576 |
| 1.1 |
0.651 |
12.60 |
0.00346 |
0.000935 |
0.001630 |
0.00529 |
| 1.2 |
0.584 |
15.80 |
0.00346 |
0.000996 |
0.001510 |
0.00541 |
| 1.3 |
0.543 |
20.00 |
0.00346 |
0.001040 |
0.001420 |
0.00550 |
| 1.4 |
0.499 |
25.10 |
0.00333 |
0.001040 |
0.001300 |
0.00536 |
| 1.5 |
0.462 |
31.60 |
0.00333 |
0.001110 |
0.001150 |
0.00551 |
| 1.6 |
0.414 |
39.80 |
0.00287 |
0.001080 |
0.000751 |
0.00499 |
| 1.7 |
0.358 |
50.10 |
0.00283 |
0.001140 |
0.000598 |
0.00507 |
| 1.8 |
0.281 |
63.10 |
0.00280 |
0.001330 |
0.000202 |
0.00540 |
| 1.9 |
0.241 |
79.40 |
0.00264 |
0.001400 |
-0.000104 |
0.00538 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00361 |
0.000724 |
0.002150 |
0.00526 |
| 0.1 |
1.26 |
0.842 |
0.00367 |
0.000854 |
0.001990 |
0.00534 |
| 0.2 |
1.58 |
0.838 |
0.00368 |
0.000858 |
0.002000 |
0.00536 |
| 0.3 |
2.00 |
0.828 |
0.00374 |
0.000871 |
0.002030 |
0.00544 |
| 0.4 |
2.51 |
0.790 |
0.00393 |
0.000921 |
0.002130 |
0.00574 |
| 0.5 |
3.16 |
0.774 |
0.00401 |
0.000940 |
0.002170 |
0.00585 |
| 0.6 |
3.98 |
0.769 |
0.00403 |
0.000945 |
0.002180 |
0.00588 |
| 0.7 |
5.01 |
0.755 |
0.00391 |
0.000938 |
0.002070 |
0.00575 |
| 0.8 |
6.31 |
0.717 |
0.00391 |
0.000963 |
0.002020 |
0.00580 |
| 0.9 |
7.94 |
0.698 |
0.00401 |
0.000990 |
0.002070 |
0.00595 |
| 1.0 |
10.00 |
0.685 |
0.00386 |
0.000978 |
0.001940 |
0.00577 |
| 1.1 |
12.60 |
0.651 |
0.00339 |
0.000935 |
0.001550 |
0.00522 |
| 1.2 |
15.80 |
0.584 |
0.00349 |
0.000996 |
0.001530 |
0.00544 |
| 1.3 |
20.00 |
0.543 |
0.00351 |
0.001040 |
0.001470 |
0.00555 |
| 1.4 |
25.10 |
0.499 |
0.00323 |
0.001040 |
0.001200 |
0.00526 |
| 1.5 |
31.60 |
0.462 |
0.00344 |
0.001110 |
0.001260 |
0.00562 |
| 1.6 |
39.80 |
0.414 |
0.00287 |
0.001080 |
0.000751 |
0.00499 |
| 1.7 |
50.10 |
0.358 |
0.00283 |
0.001140 |
0.000598 |
0.00507 |
| 1.8 |
63.10 |
0.281 |
0.00280 |
0.001330 |
0.000202 |
0.00540 |
| 1.9 |
79.40 |
0.241 |
0.00264 |
0.001400 |
-0.000104 |
0.00538 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.169 |
0.220 |
-0.262 |
0.601 |
| 0.1 |
0.842 |
1.26 |
0.169 |
0.241 |
-0.303 |
0.641 |
| 0.2 |
0.838 |
1.58 |
0.169 |
0.241 |
-0.304 |
0.643 |
| 0.3 |
0.828 |
2.00 |
0.169 |
0.244 |
-0.308 |
0.647 |
| 0.4 |
0.790 |
2.51 |
0.169 |
0.252 |
-0.325 |
0.663 |
| 0.5 |
0.774 |
3.16 |
0.169 |
0.255 |
-0.331 |
0.670 |
| 0.6 |
0.769 |
3.98 |
0.169 |
0.256 |
-0.333 |
0.671 |
| 0.7 |
0.755 |
5.01 |
0.169 |
0.255 |
-0.330 |
0.669 |
| 0.8 |
0.717 |
6.31 |
0.169 |
0.259 |
-0.339 |
0.678 |
| 0.9 |
0.698 |
7.94 |
0.169 |
0.264 |
-0.348 |
0.687 |
| 1.0 |
0.685 |
10.00 |
0.169 |
0.262 |
-0.344 |
0.683 |
| 1.1 |
0.651 |
12.60 |
0.253 |
0.245 |
-0.228 |
0.734 |
| 1.2 |
0.584 |
15.80 |
0.253 |
0.256 |
-0.250 |
0.755 |
| 1.3 |
0.543 |
20.00 |
0.253 |
0.264 |
-0.265 |
0.771 |
| 1.4 |
0.499 |
25.10 |
0.280 |
0.261 |
-0.232 |
0.792 |
| 1.5 |
0.462 |
31.60 |
0.280 |
0.275 |
-0.260 |
0.819 |
| 1.6 |
0.414 |
39.80 |
0.379 |
0.261 |
-0.132 |
0.891 |
| 1.7 |
0.358 |
50.10 |
0.388 |
0.271 |
-0.144 |
0.920 |
| 1.8 |
0.281 |
63.10 |
0.394 |
0.308 |
-0.210 |
0.998 |
| 1.9 |
0.241 |
79.40 |
0.430 |
0.320 |
-0.198 |
1.060 |
IgG_PE_BioRV144_V2_C
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00361 |
0.000724 |
2.19e-03 |
0.00503 |
| 0.1 |
0.9480 |
1.26 |
0.00352 |
0.000778 |
1.99e-03 |
0.00504 |
| 0.2 |
0.9470 |
1.58 |
0.00352 |
0.000779 |
1.99e-03 |
0.00504 |
| 0.3 |
0.9470 |
2.00 |
0.00352 |
0.000779 |
1.99e-03 |
0.00504 |
| 0.4 |
0.9470 |
2.51 |
0.00352 |
0.000779 |
1.99e-03 |
0.00504 |
| 0.5 |
0.9410 |
3.16 |
0.00352 |
0.000786 |
1.97e-03 |
0.00506 |
| 0.6 |
0.9350 |
3.98 |
0.00341 |
0.000773 |
1.89e-03 |
0.00492 |
| 0.7 |
0.9350 |
5.01 |
0.00341 |
0.000773 |
1.89e-03 |
0.00492 |
| 0.8 |
0.9350 |
6.31 |
0.00326 |
0.000754 |
1.78e-03 |
0.00474 |
| 0.9 |
0.9270 |
7.94 |
0.00300 |
0.000720 |
1.59e-03 |
0.00441 |
| 1.0 |
0.9050 |
10.00 |
0.00300 |
0.000737 |
1.56e-03 |
0.00445 |
| 1.1 |
0.8840 |
12.60 |
0.00297 |
0.000732 |
1.53e-03 |
0.00440 |
| 1.2 |
0.8700 |
15.80 |
0.00297 |
0.000745 |
1.51e-03 |
0.00443 |
| 1.3 |
0.8480 |
20.00 |
0.00289 |
0.000741 |
1.44e-03 |
0.00435 |
| 1.4 |
0.8050 |
25.10 |
0.00284 |
0.000752 |
1.37e-03 |
0.00432 |
| 1.5 |
0.7530 |
31.60 |
0.00280 |
0.000768 |
1.30e-03 |
0.00431 |
| 1.6 |
0.7180 |
39.80 |
0.00238 |
0.000719 |
9.68e-04 |
0.00379 |
| 1.7 |
0.6560 |
50.10 |
0.00238 |
0.000762 |
8.84e-04 |
0.00387 |
| 1.8 |
0.6040 |
63.10 |
0.00233 |
0.000784 |
7.96e-04 |
0.00387 |
| 1.9 |
0.5470 |
79.40 |
0.00233 |
0.000833 |
6.99e-04 |
0.00397 |
| 2.0 |
0.4630 |
100.00 |
0.00233 |
0.000854 |
6.57e-04 |
0.00401 |
| 2.1 |
0.4140 |
126.00 |
0.00233 |
0.000918 |
5.33e-04 |
0.00413 |
| 2.2 |
0.3610 |
158.00 |
0.00233 |
0.001070 |
2.38e-04 |
0.00443 |
| 2.3 |
0.3250 |
200.00 |
0.00233 |
0.001210 |
-3.78e-05 |
0.00470 |
| 2.4 |
0.2830 |
251.00 |
0.00233 |
0.001160 |
5.90e-05 |
0.00461 |
| 2.5 |
0.2420 |
316.00 |
0.00233 |
0.001270 |
-1.65e-04 |
0.00483 |
| 2.6 |
0.1980 |
398.00 |
0.00233 |
0.001540 |
-6.96e-04 |
0.00536 |
| 2.7 |
0.1400 |
501.00 |
0.00233 |
0.002290 |
-2.16e-03 |
0.00683 |
| 2.8 |
0.1120 |
631.00 |
0.00233 |
0.002170 |
-1.92e-03 |
0.00659 |
| 2.9 |
0.0985 |
794.00 |
0.00233 |
0.002290 |
-2.15e-03 |
0.00681 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00361 |
0.000724 |
0.002110 |
0.00517 |
| 0.1 |
1.26 |
0.9480 |
0.00351 |
0.000778 |
0.001980 |
0.00503 |
| 0.2 |
1.58 |
0.9470 |
0.00351 |
0.000779 |
0.001980 |
0.00504 |
| 0.3 |
2.00 |
0.9470 |
0.00351 |
0.000779 |
0.001980 |
0.00504 |
| 0.4 |
2.51 |
0.9470 |
0.00351 |
0.000779 |
0.001980 |
0.00504 |
| 0.5 |
3.16 |
0.9410 |
0.00354 |
0.000786 |
0.002000 |
0.00508 |
| 0.6 |
3.98 |
0.9350 |
0.00341 |
0.000773 |
0.001890 |
0.00492 |
| 0.7 |
5.01 |
0.9350 |
0.00341 |
0.000773 |
0.001890 |
0.00492 |
| 0.8 |
6.31 |
0.9350 |
0.00326 |
0.000754 |
0.001780 |
0.00474 |
| 0.9 |
7.94 |
0.9270 |
0.00297 |
0.000720 |
0.001560 |
0.00438 |
| 1.0 |
10.00 |
0.9050 |
0.00304 |
0.000737 |
0.001590 |
0.00448 |
| 1.1 |
12.60 |
0.8840 |
0.00294 |
0.000732 |
0.001510 |
0.00438 |
| 1.2 |
15.80 |
0.8700 |
0.00299 |
0.000745 |
0.001530 |
0.00445 |
| 1.3 |
20.00 |
0.8480 |
0.00289 |
0.000741 |
0.001440 |
0.00435 |
| 1.4 |
25.10 |
0.8050 |
0.00284 |
0.000752 |
0.001370 |
0.00432 |
| 1.5 |
31.60 |
0.7530 |
0.00280 |
0.000768 |
0.001300 |
0.00431 |
| 1.6 |
39.80 |
0.7180 |
0.00237 |
0.000719 |
0.000960 |
0.00378 |
| 1.7 |
50.10 |
0.6560 |
0.00238 |
0.000762 |
0.000891 |
0.00388 |
| 1.8 |
63.10 |
0.6040 |
0.00233 |
0.000784 |
0.000792 |
0.00386 |
| 1.9 |
79.40 |
0.5470 |
0.00233 |
0.000833 |
0.000696 |
0.00396 |
| 2.0 |
100.00 |
0.4630 |
0.00210 |
0.000854 |
0.000422 |
0.00377 |
| 2.1 |
126.00 |
0.4140 |
0.00225 |
0.000918 |
0.000455 |
0.00405 |
| 2.2 |
158.00 |
0.3610 |
0.00257 |
0.001070 |
0.000471 |
0.00466 |
| 2.3 |
200.00 |
0.3250 |
0.00289 |
0.001210 |
0.000521 |
0.00526 |
| 2.4 |
251.00 |
0.2830 |
0.00238 |
0.001160 |
0.000111 |
0.00466 |
| 2.5 |
316.00 |
0.2420 |
0.00235 |
0.001270 |
-0.000148 |
0.00485 |
| 2.6 |
398.00 |
0.1980 |
0.00285 |
0.001540 |
-0.000174 |
0.00588 |
| 2.7 |
501.00 |
0.1400 |
0.00423 |
0.002290 |
-0.000267 |
0.00872 |
| 2.8 |
631.00 |
0.1120 |
0.00348 |
0.002170 |
-0.000771 |
0.00774 |
| 2.9 |
794.00 |
0.0985 |
0.00365 |
0.002290 |
-0.000831 |
0.00813 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.220 |
0.214 |
-0.19900 |
0.638 |
| 0.1 |
0.9480 |
1.26 |
0.240 |
0.220 |
-0.19000 |
0.671 |
| 0.2 |
0.9470 |
1.58 |
0.240 |
0.220 |
-0.19100 |
0.671 |
| 0.3 |
0.9470 |
2.00 |
0.240 |
0.220 |
-0.19100 |
0.671 |
| 0.4 |
0.9470 |
2.51 |
0.240 |
0.220 |
-0.19100 |
0.671 |
| 0.5 |
0.9410 |
3.16 |
0.240 |
0.221 |
-0.19300 |
0.674 |
| 0.6 |
0.9350 |
3.98 |
0.263 |
0.216 |
-0.16000 |
0.687 |
| 0.7 |
0.9350 |
5.01 |
0.263 |
0.216 |
-0.16000 |
0.687 |
| 0.8 |
0.9350 |
6.31 |
0.296 |
0.209 |
-0.11400 |
0.706 |
| 0.9 |
0.9270 |
7.94 |
0.351 |
0.197 |
-0.03520 |
0.737 |
| 1.0 |
0.9050 |
10.00 |
0.351 |
0.200 |
-0.04100 |
0.743 |
| 1.1 |
0.8840 |
12.60 |
0.359 |
0.198 |
-0.02920 |
0.748 |
| 1.2 |
0.8700 |
15.80 |
0.359 |
0.200 |
-0.03370 |
0.752 |
| 1.3 |
0.8480 |
20.00 |
0.375 |
0.198 |
-0.01330 |
0.763 |
| 1.4 |
0.8050 |
25.10 |
0.385 |
0.199 |
-0.00433 |
0.775 |
| 1.5 |
0.7530 |
31.60 |
0.394 |
0.201 |
0.00114 |
0.788 |
| 1.6 |
0.7180 |
39.80 |
0.486 |
0.182 |
0.12900 |
0.844 |
| 1.7 |
0.6560 |
50.10 |
0.486 |
0.190 |
0.11300 |
0.860 |
| 1.8 |
0.6040 |
63.10 |
0.496 |
0.194 |
0.11700 |
0.875 |
| 1.9 |
0.5470 |
79.40 |
0.496 |
0.203 |
0.09810 |
0.894 |
| 2.0 |
0.4630 |
100.00 |
0.496 |
0.207 |
0.09010 |
0.902 |
| 2.1 |
0.4140 |
126.00 |
0.496 |
0.219 |
0.06600 |
0.926 |
| 2.2 |
0.3610 |
158.00 |
0.496 |
0.249 |
0.00756 |
0.985 |
| 2.3 |
0.3250 |
200.00 |
0.496 |
0.278 |
-0.04810 |
1.040 |
| 2.4 |
0.2830 |
251.00 |
0.496 |
0.268 |
-0.02850 |
1.020 |
| 2.5 |
0.2420 |
316.00 |
0.496 |
0.291 |
-0.07410 |
1.070 |
| 2.6 |
0.1980 |
398.00 |
0.496 |
0.347 |
-0.18400 |
1.180 |
| 2.7 |
0.1400 |
501.00 |
0.496 |
0.504 |
-0.49300 |
1.480 |
| 2.8 |
0.1120 |
631.00 |
0.496 |
0.478 |
-0.44200 |
1.430 |
| 2.9 |
0.0985 |
794.00 |
0.496 |
0.503 |
-0.48900 |
1.480 |
RV144 (42 month)
- Adjustment covariates: dem_sex, BRA_risk
- Event time variable: HIVwk42fu
- Event type variable: HIVwk42
- Weight variable: sample_weight
- Reference timepoint: 1014 days
- All learners: GLM
IgG V1V2 B.CaseA-gp70
Monotone

| 0.0 |
1.000 |
1.00 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| 0.1 |
0.995 |
1.26 |
0.00584 |
0.001020 |
0.003840 |
0.00785 |
| 0.2 |
0.995 |
1.58 |
0.00584 |
0.001020 |
0.003840 |
0.00785 |
| 0.3 |
0.995 |
2.00 |
0.00584 |
0.001020 |
0.003840 |
0.00785 |
| 0.4 |
0.994 |
2.51 |
0.00584 |
0.001020 |
0.003840 |
0.00785 |
| 0.5 |
0.994 |
3.16 |
0.00584 |
0.001020 |
0.003840 |
0.00785 |
| 0.6 |
0.994 |
3.98 |
0.00584 |
0.001020 |
0.003840 |
0.00785 |
| 0.7 |
0.994 |
5.01 |
0.00584 |
0.001020 |
0.003840 |
0.00785 |
| 0.8 |
0.992 |
6.31 |
0.00584 |
0.001020 |
0.003840 |
0.00785 |
| 0.9 |
0.992 |
7.94 |
0.00584 |
0.001020 |
0.003840 |
0.00785 |
| 1.0 |
0.989 |
10.00 |
0.00584 |
0.001030 |
0.003830 |
0.00786 |
| 1.1 |
0.987 |
12.60 |
0.00584 |
0.001030 |
0.003830 |
0.00786 |
| 1.2 |
0.981 |
15.80 |
0.00584 |
0.001030 |
0.003820 |
0.00787 |
| 1.3 |
0.972 |
20.00 |
0.00584 |
0.001040 |
0.003800 |
0.00789 |
| 1.4 |
0.970 |
25.10 |
0.00584 |
0.001030 |
0.003820 |
0.00785 |
| 1.5 |
0.965 |
31.60 |
0.00584 |
0.001030 |
0.003810 |
0.00787 |
| 1.6 |
0.956 |
39.80 |
0.00584 |
0.001040 |
0.003790 |
0.00788 |
| 1.7 |
0.951 |
50.10 |
0.00576 |
0.001030 |
0.003740 |
0.00779 |
| 1.8 |
0.935 |
63.10 |
0.00541 |
0.001010 |
0.003440 |
0.00738 |
| 1.9 |
0.933 |
79.40 |
0.00530 |
0.000992 |
0.003360 |
0.00725 |
| 2.0 |
0.920 |
100.00 |
0.00530 |
0.001010 |
0.003330 |
0.00728 |
| 2.1 |
0.905 |
126.00 |
0.00527 |
0.001010 |
0.003290 |
0.00724 |
| 2.2 |
0.878 |
158.00 |
0.00525 |
0.001020 |
0.003250 |
0.00725 |
| 2.3 |
0.825 |
200.00 |
0.00502 |
0.001020 |
0.003010 |
0.00702 |
| 2.4 |
0.793 |
251.00 |
0.00488 |
0.001000 |
0.002910 |
0.00684 |
| 2.5 |
0.730 |
316.00 |
0.00488 |
0.001070 |
0.002780 |
0.00698 |
| 2.6 |
0.668 |
398.00 |
0.00488 |
0.001090 |
0.002740 |
0.00702 |
| 2.7 |
0.612 |
501.00 |
0.00488 |
0.001130 |
0.002670 |
0.00709 |
| 2.8 |
0.518 |
631.00 |
0.00488 |
0.001230 |
0.002460 |
0.00730 |
| 2.9 |
0.481 |
794.00 |
0.00488 |
0.001370 |
0.002200 |
0.00756 |
| 3.0 |
0.409 |
1000.00 |
0.00488 |
0.001540 |
0.001850 |
0.00790 |
| 3.1 |
0.349 |
1260.00 |
0.00488 |
0.001580 |
0.001770 |
0.00798 |
| 3.2 |
0.278 |
1580.00 |
0.00488 |
0.001870 |
0.001210 |
0.00854 |
| 3.3 |
0.204 |
2000.00 |
0.00488 |
0.002220 |
0.000531 |
0.00923 |
| 3.4 |
0.164 |
2510.00 |
0.00468 |
0.002270 |
0.000232 |
0.00913 |
| 3.5 |
0.132 |
3160.00 |
0.00330 |
0.002060 |
-0.000725 |
0.00733 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.995 |
0.00582 |
0.001020 |
0.003820 |
0.00782 |
| 0.2 |
1.58 |
0.995 |
0.00582 |
0.001020 |
0.003820 |
0.00782 |
| 0.3 |
2.00 |
0.995 |
0.00582 |
0.001020 |
0.003820 |
0.00782 |
| 0.4 |
2.51 |
0.994 |
0.00583 |
0.001020 |
0.003820 |
0.00783 |
| 0.5 |
3.16 |
0.994 |
0.00583 |
0.001020 |
0.003820 |
0.00783 |
| 0.6 |
3.98 |
0.994 |
0.00583 |
0.001020 |
0.003820 |
0.00783 |
| 0.7 |
5.01 |
0.994 |
0.00583 |
0.001020 |
0.003820 |
0.00783 |
| 0.8 |
6.31 |
0.992 |
0.00583 |
0.001020 |
0.003830 |
0.00784 |
| 0.9 |
7.94 |
0.992 |
0.00583 |
0.001020 |
0.003830 |
0.00784 |
| 1.0 |
10.00 |
0.989 |
0.00585 |
0.001030 |
0.003840 |
0.00787 |
| 1.1 |
12.60 |
0.987 |
0.00586 |
0.001030 |
0.003840 |
0.00788 |
| 1.2 |
15.80 |
0.981 |
0.00589 |
0.001030 |
0.003860 |
0.00791 |
| 1.3 |
20.00 |
0.972 |
0.00594 |
0.001040 |
0.003890 |
0.00798 |
| 1.4 |
25.10 |
0.970 |
0.00580 |
0.001030 |
0.003780 |
0.00782 |
| 1.5 |
31.60 |
0.965 |
0.00583 |
0.001030 |
0.003800 |
0.00785 |
| 1.6 |
39.80 |
0.956 |
0.00589 |
0.001040 |
0.003840 |
0.00793 |
| 1.7 |
50.10 |
0.951 |
0.00576 |
0.001030 |
0.003740 |
0.00779 |
| 1.8 |
63.10 |
0.935 |
0.00541 |
0.001010 |
0.003440 |
0.00738 |
| 1.9 |
79.40 |
0.933 |
0.00527 |
0.000992 |
0.003320 |
0.00721 |
| 2.0 |
100.00 |
0.920 |
0.00534 |
0.001010 |
0.003370 |
0.00732 |
| 2.1 |
126.00 |
0.905 |
0.00527 |
0.001010 |
0.003290 |
0.00724 |
| 2.2 |
158.00 |
0.878 |
0.00525 |
0.001020 |
0.003250 |
0.00725 |
| 2.3 |
200.00 |
0.825 |
0.00502 |
0.001020 |
0.003010 |
0.00702 |
| 2.4 |
251.00 |
0.793 |
0.00469 |
0.001000 |
0.002720 |
0.00665 |
| 2.5 |
316.00 |
0.730 |
0.00489 |
0.001070 |
0.002790 |
0.00699 |
| 2.6 |
398.00 |
0.668 |
0.00469 |
0.001090 |
0.002550 |
0.00684 |
| 2.7 |
501.00 |
0.612 |
0.00461 |
0.001130 |
0.002400 |
0.00682 |
| 2.8 |
631.00 |
0.518 |
0.00463 |
0.001230 |
0.002220 |
0.00705 |
| 2.9 |
794.00 |
0.481 |
0.00511 |
0.001370 |
0.002440 |
0.00779 |
| 3.0 |
1000.00 |
0.409 |
0.00515 |
0.001540 |
0.002130 |
0.00818 |
| 3.1 |
1260.00 |
0.349 |
0.00511 |
0.001580 |
0.002000 |
0.00821 |
| 3.2 |
1580.00 |
0.278 |
0.00529 |
0.001870 |
0.001630 |
0.00896 |
| 3.3 |
2000.00 |
0.204 |
0.00515 |
0.002220 |
0.000806 |
0.00950 |
| 3.4 |
2510.00 |
0.164 |
0.00468 |
0.002270 |
0.000232 |
0.00913 |
| 3.5 |
3160.00 |
0.132 |
0.00330 |
0.002060 |
-0.000725 |
0.00733 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.228 |
0.164 |
-0.09420 |
0.549 |
| 0.1 |
0.995 |
1.26 |
0.241 |
0.172 |
-0.09590 |
0.578 |
| 0.2 |
0.995 |
1.58 |
0.241 |
0.172 |
-0.09590 |
0.578 |
| 0.3 |
0.995 |
2.00 |
0.241 |
0.172 |
-0.09590 |
0.578 |
| 0.4 |
0.994 |
2.51 |
0.241 |
0.172 |
-0.09610 |
0.578 |
| 0.5 |
0.994 |
3.16 |
0.241 |
0.172 |
-0.09610 |
0.578 |
| 0.6 |
0.994 |
3.98 |
0.241 |
0.172 |
-0.09610 |
0.578 |
| 0.7 |
0.994 |
5.01 |
0.241 |
0.172 |
-0.09610 |
0.578 |
| 0.8 |
0.992 |
6.31 |
0.241 |
0.172 |
-0.09640 |
0.579 |
| 0.9 |
0.992 |
7.94 |
0.241 |
0.172 |
-0.09640 |
0.579 |
| 1.0 |
0.989 |
10.00 |
0.241 |
0.173 |
-0.09720 |
0.580 |
| 1.1 |
0.987 |
12.60 |
0.241 |
0.173 |
-0.09740 |
0.580 |
| 1.2 |
0.981 |
15.80 |
0.241 |
0.173 |
-0.09840 |
0.581 |
| 1.3 |
0.972 |
20.00 |
0.241 |
0.174 |
-0.09990 |
0.582 |
| 1.4 |
0.970 |
25.10 |
0.242 |
0.173 |
-0.09630 |
0.580 |
| 1.5 |
0.965 |
31.60 |
0.242 |
0.173 |
-0.09740 |
0.582 |
| 1.6 |
0.956 |
39.80 |
0.242 |
0.174 |
-0.09930 |
0.583 |
| 1.7 |
0.951 |
50.10 |
0.252 |
0.172 |
-0.08590 |
0.589 |
| 1.8 |
0.935 |
63.10 |
0.298 |
0.165 |
-0.02590 |
0.622 |
| 1.9 |
0.933 |
79.40 |
0.311 |
0.163 |
-0.00742 |
0.630 |
| 2.0 |
0.920 |
100.00 |
0.311 |
0.164 |
-0.01060 |
0.633 |
| 2.1 |
0.905 |
126.00 |
0.316 |
0.164 |
-0.00539 |
0.637 |
| 2.2 |
0.878 |
158.00 |
0.318 |
0.165 |
-0.00559 |
0.641 |
| 2.3 |
0.825 |
200.00 |
0.349 |
0.163 |
0.03000 |
0.667 |
| 2.4 |
0.793 |
251.00 |
0.367 |
0.159 |
0.05470 |
0.678 |
| 2.5 |
0.730 |
316.00 |
0.367 |
0.166 |
0.04040 |
0.693 |
| 2.6 |
0.668 |
398.00 |
0.367 |
0.169 |
0.03560 |
0.697 |
| 2.7 |
0.612 |
501.00 |
0.367 |
0.173 |
0.02800 |
0.705 |
| 2.8 |
0.518 |
631.00 |
0.367 |
0.184 |
0.00496 |
0.728 |
| 2.9 |
0.481 |
794.00 |
0.367 |
0.200 |
-0.02460 |
0.758 |
| 3.0 |
0.409 |
1000.00 |
0.367 |
0.220 |
-0.06520 |
0.798 |
| 3.1 |
0.349 |
1260.00 |
0.367 |
0.225 |
-0.07450 |
0.808 |
| 3.2 |
0.278 |
1580.00 |
0.367 |
0.259 |
-0.14200 |
0.875 |
| 3.3 |
0.204 |
2000.00 |
0.367 |
0.302 |
-0.22600 |
0.959 |
| 3.4 |
0.164 |
2510.00 |
0.392 |
0.308 |
-0.21100 |
0.995 |
| 3.5 |
0.132 |
3160.00 |
0.571 |
0.274 |
0.03390 |
1.110 |
IgG V1V2 C.1086-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00597 |
0.000929 |
0.00415 |
0.00779 |
| 0.1 |
0.9950 |
1.26 |
0.00597 |
0.001040 |
0.00394 |
0.00800 |
| 0.2 |
0.9950 |
1.58 |
0.00597 |
0.001040 |
0.00394 |
0.00800 |
| 0.3 |
0.9950 |
2.00 |
0.00597 |
0.001040 |
0.00394 |
0.00800 |
| 0.4 |
0.9940 |
2.51 |
0.00597 |
0.001040 |
0.00393 |
0.00800 |
| 0.5 |
0.9920 |
3.16 |
0.00597 |
0.001040 |
0.00393 |
0.00800 |
| 0.6 |
0.9920 |
3.98 |
0.00597 |
0.001040 |
0.00393 |
0.00800 |
| 0.7 |
0.9920 |
5.01 |
0.00584 |
0.001020 |
0.00383 |
0.00785 |
| 0.8 |
0.9920 |
6.31 |
0.00584 |
0.001020 |
0.00383 |
0.00785 |
| 0.9 |
0.9920 |
7.94 |
0.00584 |
0.001020 |
0.00383 |
0.00785 |
| 1.0 |
0.9920 |
10.00 |
0.00584 |
0.001020 |
0.00383 |
0.00785 |
| 1.1 |
0.9900 |
12.60 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.2 |
0.9900 |
15.80 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.3 |
0.9900 |
20.00 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.4 |
0.9900 |
25.10 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.5 |
0.9900 |
31.60 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.6 |
0.9900 |
39.80 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.7 |
0.9900 |
50.10 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.8 |
0.9900 |
63.10 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.9 |
0.9890 |
79.40 |
0.00584 |
0.001030 |
0.00382 |
0.00786 |
| 2.0 |
0.9880 |
100.00 |
0.00573 |
0.001010 |
0.00374 |
0.00771 |
| 2.1 |
0.9870 |
126.00 |
0.00573 |
0.001020 |
0.00374 |
0.00772 |
| 2.2 |
0.9870 |
158.00 |
0.00573 |
0.001020 |
0.00374 |
0.00772 |
| 2.3 |
0.9870 |
200.00 |
0.00573 |
0.001020 |
0.00374 |
0.00772 |
| 2.4 |
0.9870 |
251.00 |
0.00573 |
0.001020 |
0.00374 |
0.00772 |
| 2.5 |
0.9810 |
316.00 |
0.00573 |
0.001020 |
0.00372 |
0.00773 |
| 2.6 |
0.9810 |
398.00 |
0.00573 |
0.001020 |
0.00372 |
0.00773 |
| 2.7 |
0.9810 |
501.00 |
0.00562 |
0.001010 |
0.00365 |
0.00759 |
| 2.8 |
0.9760 |
631.00 |
0.00562 |
0.001010 |
0.00364 |
0.00760 |
| 2.9 |
0.9670 |
794.00 |
0.00540 |
0.000990 |
0.00346 |
0.00735 |
| 3.0 |
0.9670 |
1000.00 |
0.00540 |
0.000990 |
0.00346 |
0.00735 |
| 3.1 |
0.9630 |
1260.00 |
0.00540 |
0.000994 |
0.00346 |
0.00735 |
| 3.2 |
0.9520 |
1580.00 |
0.00531 |
0.000988 |
0.00338 |
0.00725 |
| 3.3 |
0.9370 |
2000.00 |
0.00527 |
0.000951 |
0.00341 |
0.00714 |
| 3.4 |
0.9160 |
2510.00 |
0.00527 |
0.000961 |
0.00339 |
0.00716 |
| 3.5 |
0.8940 |
3160.00 |
0.00527 |
0.000984 |
0.00334 |
0.00720 |
| 3.6 |
0.8580 |
3980.00 |
0.00527 |
0.001010 |
0.00329 |
0.00725 |
| 3.7 |
0.7630 |
5010.00 |
0.00527 |
0.001110 |
0.00309 |
0.00746 |
| 3.8 |
0.6750 |
6310.00 |
0.00527 |
0.001170 |
0.00298 |
0.00756 |
| 3.9 |
0.5820 |
7940.00 |
0.00527 |
0.001360 |
0.00261 |
0.00793 |
| 4.0 |
0.4960 |
10000.00 |
0.00527 |
0.001540 |
0.00226 |
0.00829 |
| 4.1 |
0.4170 |
12600.00 |
0.00500 |
0.001430 |
0.00220 |
0.00780 |
| 4.2 |
0.3270 |
15800.00 |
0.00500 |
0.001710 |
0.00165 |
0.00835 |
| 4.3 |
0.2430 |
20000.00 |
0.00500 |
0.001950 |
0.00117 |
0.00883 |
| 4.4 |
0.0777 |
25100.00 |
0.00500 |
0.004890 |
-0.00459 |
0.01460 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.00392 |
0.00797 |
| 0.1 |
1.26 |
0.9950 |
0.00596 |
0.001040 |
0.00393 |
0.00800 |
| 0.2 |
1.58 |
0.9950 |
0.00596 |
0.001040 |
0.00393 |
0.00800 |
| 0.3 |
2.00 |
0.9950 |
0.00596 |
0.001040 |
0.00393 |
0.00800 |
| 0.4 |
2.51 |
0.9940 |
0.00597 |
0.001040 |
0.00394 |
0.00801 |
| 0.5 |
3.16 |
0.9920 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 0.6 |
3.98 |
0.9920 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 0.7 |
5.01 |
0.9920 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 0.8 |
6.31 |
0.9920 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 0.9 |
7.94 |
0.9920 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.0 |
10.00 |
0.9920 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.1 |
12.60 |
0.9900 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.2 |
15.80 |
0.9900 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.3 |
20.00 |
0.9900 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.4 |
25.10 |
0.9900 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.5 |
31.60 |
0.9900 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.6 |
39.80 |
0.9900 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.7 |
50.10 |
0.9900 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.8 |
63.10 |
0.9900 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.9 |
79.40 |
0.9890 |
0.00586 |
0.001030 |
0.00384 |
0.00787 |
| 2.0 |
100.00 |
0.9880 |
0.00571 |
0.001010 |
0.00372 |
0.00770 |
| 2.1 |
126.00 |
0.9870 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.2 |
158.00 |
0.9870 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.3 |
200.00 |
0.9870 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.4 |
251.00 |
0.9870 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.5 |
316.00 |
0.9810 |
0.00575 |
0.001020 |
0.00374 |
0.00775 |
| 2.6 |
398.00 |
0.9810 |
0.00575 |
0.001020 |
0.00374 |
0.00775 |
| 2.7 |
501.00 |
0.9810 |
0.00560 |
0.001010 |
0.00363 |
0.00758 |
| 2.8 |
631.00 |
0.9760 |
0.00564 |
0.001010 |
0.00366 |
0.00762 |
| 2.9 |
794.00 |
0.9670 |
0.00540 |
0.000990 |
0.00346 |
0.00734 |
| 3.0 |
1000.00 |
0.9670 |
0.00540 |
0.000990 |
0.00346 |
0.00734 |
| 3.1 |
1260.00 |
0.9630 |
0.00542 |
0.000994 |
0.00347 |
0.00737 |
| 3.2 |
1580.00 |
0.9520 |
0.00531 |
0.000988 |
0.00338 |
0.00725 |
| 3.3 |
2000.00 |
0.9370 |
0.00492 |
0.000951 |
0.00306 |
0.00678 |
| 3.4 |
2510.00 |
0.9160 |
0.00489 |
0.000961 |
0.00301 |
0.00678 |
| 3.5 |
3160.00 |
0.8940 |
0.00500 |
0.000984 |
0.00307 |
0.00693 |
| 3.6 |
3980.00 |
0.8580 |
0.00504 |
0.001010 |
0.00306 |
0.00702 |
| 3.7 |
5010.00 |
0.7630 |
0.00534 |
0.001110 |
0.00316 |
0.00753 |
| 3.8 |
6310.00 |
0.6750 |
0.00530 |
0.001170 |
0.00301 |
0.00760 |
| 3.9 |
7940.00 |
0.5820 |
0.00585 |
0.001360 |
0.00319 |
0.00851 |
| 4.0 |
10000.00 |
0.4960 |
0.00615 |
0.001540 |
0.00313 |
0.00916 |
| 4.1 |
12600.00 |
0.4170 |
0.00471 |
0.001430 |
0.00191 |
0.00751 |
| 4.2 |
15800.00 |
0.3270 |
0.00532 |
0.001710 |
0.00197 |
0.00867 |
| 4.3 |
20000.00 |
0.2430 |
0.00528 |
0.001950 |
0.00146 |
0.00911 |
| 4.4 |
25100.00 |
0.0777 |
0.00646 |
0.004890 |
-0.00313 |
0.01610 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.225 |
0.164 |
-0.097100 |
0.547 |
| 0.1 |
0.9950 |
1.26 |
0.225 |
0.175 |
-0.118000 |
0.568 |
| 0.2 |
0.9950 |
1.58 |
0.225 |
0.175 |
-0.118000 |
0.568 |
| 0.3 |
0.9950 |
2.00 |
0.225 |
0.175 |
-0.118000 |
0.568 |
| 0.4 |
0.9940 |
2.51 |
0.225 |
0.175 |
-0.118000 |
0.568 |
| 0.5 |
0.9920 |
3.16 |
0.225 |
0.175 |
-0.118000 |
0.569 |
| 0.6 |
0.9920 |
3.98 |
0.225 |
0.175 |
-0.118000 |
0.569 |
| 0.7 |
0.9920 |
5.01 |
0.242 |
0.172 |
-0.096000 |
0.579 |
| 0.8 |
0.9920 |
6.31 |
0.242 |
0.172 |
-0.096000 |
0.579 |
| 0.9 |
0.9920 |
7.94 |
0.242 |
0.172 |
-0.096000 |
0.579 |
| 1.0 |
0.9920 |
10.00 |
0.242 |
0.172 |
-0.096000 |
0.579 |
| 1.1 |
0.9900 |
12.60 |
0.242 |
0.172 |
-0.096300 |
0.579 |
| 1.2 |
0.9900 |
15.80 |
0.242 |
0.172 |
-0.096300 |
0.579 |
| 1.3 |
0.9900 |
20.00 |
0.242 |
0.172 |
-0.096300 |
0.579 |
| 1.4 |
0.9900 |
25.10 |
0.242 |
0.172 |
-0.096300 |
0.579 |
| 1.5 |
0.9900 |
31.60 |
0.242 |
0.172 |
-0.096300 |
0.579 |
| 1.6 |
0.9900 |
39.80 |
0.242 |
0.172 |
-0.096300 |
0.579 |
| 1.7 |
0.9900 |
50.10 |
0.242 |
0.172 |
-0.096300 |
0.579 |
| 1.8 |
0.9900 |
63.10 |
0.242 |
0.172 |
-0.096300 |
0.579 |
| 1.9 |
0.9890 |
79.40 |
0.242 |
0.173 |
-0.096900 |
0.580 |
| 2.0 |
0.9880 |
100.00 |
0.257 |
0.170 |
-0.076100 |
0.589 |
| 2.1 |
0.9870 |
126.00 |
0.257 |
0.170 |
-0.076500 |
0.590 |
| 2.2 |
0.9870 |
158.00 |
0.257 |
0.170 |
-0.076500 |
0.590 |
| 2.3 |
0.9870 |
200.00 |
0.257 |
0.170 |
-0.076500 |
0.590 |
| 2.4 |
0.9870 |
251.00 |
0.257 |
0.170 |
-0.076500 |
0.590 |
| 2.5 |
0.9810 |
316.00 |
0.257 |
0.170 |
-0.077600 |
0.591 |
| 2.6 |
0.9810 |
398.00 |
0.257 |
0.170 |
-0.077600 |
0.591 |
| 2.7 |
0.9810 |
501.00 |
0.270 |
0.168 |
-0.058700 |
0.599 |
| 2.8 |
0.9760 |
631.00 |
0.270 |
0.168 |
-0.059600 |
0.600 |
| 2.9 |
0.9670 |
794.00 |
0.298 |
0.164 |
-0.022500 |
0.619 |
| 3.0 |
0.9670 |
1000.00 |
0.298 |
0.164 |
-0.022500 |
0.619 |
| 3.1 |
0.9630 |
1260.00 |
0.298 |
0.164 |
-0.023300 |
0.620 |
| 3.2 |
0.9520 |
1580.00 |
0.310 |
0.162 |
-0.008270 |
0.628 |
| 3.3 |
0.9370 |
2000.00 |
0.315 |
0.158 |
0.005630 |
0.625 |
| 3.4 |
0.9160 |
2510.00 |
0.315 |
0.159 |
0.003590 |
0.627 |
| 3.5 |
0.8940 |
3160.00 |
0.315 |
0.161 |
-0.000982 |
0.632 |
| 3.6 |
0.8580 |
3980.00 |
0.315 |
0.164 |
-0.006340 |
0.637 |
| 3.7 |
0.7630 |
5010.00 |
0.315 |
0.175 |
-0.027800 |
0.659 |
| 3.8 |
0.6750 |
6310.00 |
0.315 |
0.181 |
-0.039600 |
0.671 |
| 3.9 |
0.5820 |
7940.00 |
0.315 |
0.202 |
-0.080400 |
0.711 |
| 4.0 |
0.4960 |
10000.00 |
0.315 |
0.223 |
-0.121000 |
0.752 |
| 4.1 |
0.4170 |
12600.00 |
0.351 |
0.208 |
-0.056200 |
0.758 |
| 4.2 |
0.3270 |
15800.00 |
0.351 |
0.241 |
-0.121000 |
0.823 |
| 4.3 |
0.2430 |
20000.00 |
0.351 |
0.270 |
-0.179000 |
0.880 |
| 4.4 |
0.0777 |
25100.00 |
0.351 |
0.642 |
-0.908000 |
1.610 |
IgG3 V1V2 B.CaseA-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| 0.1 |
0.9800 |
1.26 |
0.00558 |
0.000993 |
0.003630 |
0.00753 |
| 0.2 |
0.9760 |
1.58 |
0.00558 |
0.000996 |
0.003630 |
0.00753 |
| 0.3 |
0.9760 |
2.00 |
0.00558 |
0.000996 |
0.003630 |
0.00753 |
| 0.4 |
0.9510 |
2.51 |
0.00558 |
0.001010 |
0.003600 |
0.00755 |
| 0.5 |
0.9510 |
3.16 |
0.00558 |
0.001010 |
0.003600 |
0.00755 |
| 0.6 |
0.9330 |
3.98 |
0.00558 |
0.001030 |
0.003560 |
0.00759 |
| 0.7 |
0.9210 |
5.01 |
0.00558 |
0.001040 |
0.003540 |
0.00762 |
| 0.8 |
0.9210 |
6.31 |
0.00558 |
0.001040 |
0.003540 |
0.00762 |
| 0.9 |
0.9120 |
7.94 |
0.00558 |
0.001040 |
0.003550 |
0.00761 |
| 1.0 |
0.8790 |
10.00 |
0.00558 |
0.001070 |
0.003470 |
0.00769 |
| 1.1 |
0.8220 |
12.60 |
0.00558 |
0.001090 |
0.003450 |
0.00771 |
| 1.2 |
0.7910 |
15.80 |
0.00558 |
0.001120 |
0.003390 |
0.00777 |
| 1.3 |
0.7510 |
20.00 |
0.00558 |
0.001160 |
0.003310 |
0.00784 |
| 1.4 |
0.7170 |
25.10 |
0.00558 |
0.001180 |
0.003270 |
0.00789 |
| 1.5 |
0.6690 |
31.60 |
0.00545 |
0.001190 |
0.003110 |
0.00778 |
| 1.6 |
0.6180 |
39.80 |
0.00545 |
0.001230 |
0.003040 |
0.00786 |
| 1.7 |
0.5140 |
50.10 |
0.00545 |
0.001410 |
0.002690 |
0.00821 |
| 1.8 |
0.4730 |
63.10 |
0.00545 |
0.001460 |
0.002580 |
0.00831 |
| 1.9 |
0.4040 |
79.40 |
0.00512 |
0.001440 |
0.002300 |
0.00793 |
| 2.0 |
0.3280 |
100.00 |
0.00512 |
0.001500 |
0.002170 |
0.00807 |
| 2.1 |
0.2790 |
126.00 |
0.00512 |
0.001780 |
0.001630 |
0.00861 |
| 2.2 |
0.2230 |
158.00 |
0.00512 |
0.002320 |
0.000566 |
0.00967 |
| 2.3 |
0.1990 |
200.00 |
0.00512 |
0.002340 |
0.000531 |
0.00971 |
| 2.4 |
0.1570 |
251.00 |
0.00512 |
0.002980 |
-0.000724 |
0.01100 |
| 2.5 |
0.1290 |
316.00 |
0.00512 |
0.003390 |
-0.001530 |
0.01180 |
| 2.6 |
0.0959 |
398.00 |
0.00512 |
0.002770 |
-0.000314 |
0.01060 |
| 2.7 |
0.0761 |
501.00 |
0.00512 |
0.003640 |
-0.002010 |
0.01220 |
| 2.8 |
0.0512 |
631.00 |
0.00512 |
0.006910 |
-0.008430 |
0.01870 |
| 2.9 |
0.0455 |
794.00 |
0.00512 |
0.009340 |
-0.013200 |
0.02340 |
| 3.0 |
0.0340 |
1000.00 |
0.00512 |
0.007420 |
-0.009430 |
0.01970 |
| 3.1 |
0.0239 |
1260.00 |
0.00512 |
0.007110 |
-0.008820 |
0.01910 |
| 3.2 |
0.0239 |
1580.00 |
0.00512 |
0.007110 |
-0.008820 |
0.01910 |
| 3.3 |
0.0239 |
2000.00 |
0.00512 |
0.007110 |
-0.008820 |
0.01910 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9800 |
0.00548 |
0.000993 |
0.003530 |
0.00743 |
| 0.2 |
1.58 |
0.9760 |
0.00550 |
0.000996 |
0.003550 |
0.00745 |
| 0.3 |
2.00 |
0.9760 |
0.00550 |
0.000996 |
0.003550 |
0.00745 |
| 0.4 |
2.51 |
0.9510 |
0.00549 |
0.001010 |
0.003510 |
0.00746 |
| 0.5 |
3.16 |
0.9510 |
0.00549 |
0.001010 |
0.003510 |
0.00746 |
| 0.6 |
3.98 |
0.9330 |
0.00559 |
0.001030 |
0.003580 |
0.00761 |
| 0.7 |
5.01 |
0.9210 |
0.00566 |
0.001040 |
0.003620 |
0.00770 |
| 0.8 |
6.31 |
0.9210 |
0.00566 |
0.001040 |
0.003620 |
0.00770 |
| 0.9 |
7.94 |
0.9120 |
0.00556 |
0.001040 |
0.003530 |
0.00759 |
| 1.0 |
10.00 |
0.8790 |
0.00575 |
0.001070 |
0.003640 |
0.00785 |
| 1.1 |
12.60 |
0.8220 |
0.00556 |
0.001090 |
0.003430 |
0.00769 |
| 1.2 |
15.80 |
0.7910 |
0.00560 |
0.001120 |
0.003420 |
0.00779 |
| 1.3 |
20.00 |
0.7510 |
0.00570 |
0.001160 |
0.003430 |
0.00796 |
| 1.4 |
25.10 |
0.7170 |
0.00562 |
0.001180 |
0.003300 |
0.00793 |
| 1.5 |
31.60 |
0.6690 |
0.00537 |
0.001190 |
0.003040 |
0.00771 |
| 1.6 |
39.80 |
0.6180 |
0.00522 |
0.001230 |
0.002810 |
0.00763 |
| 1.7 |
50.10 |
0.5140 |
0.00566 |
0.001410 |
0.002900 |
0.00842 |
| 1.8 |
63.10 |
0.4730 |
0.00557 |
0.001460 |
0.002700 |
0.00843 |
| 1.9 |
79.40 |
0.4040 |
0.00473 |
0.001440 |
0.001910 |
0.00754 |
| 2.0 |
100.00 |
0.3280 |
0.00434 |
0.001500 |
0.001390 |
0.00729 |
| 2.1 |
126.00 |
0.2790 |
0.00510 |
0.001780 |
0.001610 |
0.00858 |
| 2.2 |
158.00 |
0.2230 |
0.00650 |
0.002320 |
0.001950 |
0.01110 |
| 2.3 |
200.00 |
0.1990 |
0.00591 |
0.002340 |
0.001320 |
0.01050 |
| 2.4 |
251.00 |
0.1570 |
0.00677 |
0.002980 |
0.000927 |
0.01260 |
| 2.5 |
316.00 |
0.1290 |
0.00646 |
0.003390 |
-0.000196 |
0.01310 |
| 2.6 |
398.00 |
0.0959 |
0.00476 |
0.002770 |
-0.000669 |
0.01020 |
| 2.7 |
501.00 |
0.0761 |
0.00523 |
0.003640 |
-0.001890 |
0.01240 |
| 2.8 |
631.00 |
0.0512 |
0.00766 |
0.006910 |
-0.005890 |
0.02120 |
| 2.9 |
794.00 |
0.0455 |
0.01030 |
0.009340 |
-0.007990 |
0.02860 |
| 3.0 |
1000.00 |
0.0340 |
0.01030 |
0.007420 |
-0.004250 |
0.02480 |
| 3.1 |
1260.00 |
0.0239 |
0.01570 |
0.007110 |
0.001720 |
0.02960 |
| 3.2 |
1580.00 |
0.0239 |
0.01570 |
0.007110 |
0.001720 |
0.02960 |
| 3.3 |
2000.00 |
0.0239 |
0.01570 |
0.007110 |
0.001720 |
0.02960 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.228 |
0.164 |
-0.0942 |
0.549 |
| 0.1 |
0.9800 |
1.26 |
0.276 |
0.166 |
-0.0497 |
0.601 |
| 0.2 |
0.9760 |
1.58 |
0.276 |
0.166 |
-0.0503 |
0.601 |
| 0.3 |
0.9760 |
2.00 |
0.276 |
0.166 |
-0.0503 |
0.601 |
| 0.4 |
0.9510 |
2.51 |
0.276 |
0.167 |
-0.0526 |
0.604 |
| 0.5 |
0.9510 |
3.16 |
0.276 |
0.167 |
-0.0526 |
0.604 |
| 0.6 |
0.9330 |
3.98 |
0.276 |
0.170 |
-0.0568 |
0.608 |
| 0.7 |
0.9210 |
5.01 |
0.276 |
0.171 |
-0.0593 |
0.610 |
| 0.8 |
0.9210 |
6.31 |
0.276 |
0.171 |
-0.0593 |
0.610 |
| 0.9 |
0.9120 |
7.94 |
0.276 |
0.170 |
-0.0583 |
0.609 |
| 1.0 |
0.8790 |
10.00 |
0.276 |
0.174 |
-0.0661 |
0.617 |
| 1.1 |
0.8220 |
12.60 |
0.276 |
0.176 |
-0.0685 |
0.620 |
| 1.2 |
0.7910 |
15.80 |
0.276 |
0.179 |
-0.0747 |
0.626 |
| 1.3 |
0.7510 |
20.00 |
0.276 |
0.183 |
-0.0829 |
0.634 |
| 1.4 |
0.7170 |
25.10 |
0.276 |
0.185 |
-0.0880 |
0.639 |
| 1.5 |
0.6690 |
31.60 |
0.293 |
0.185 |
-0.0705 |
0.656 |
| 1.6 |
0.6180 |
39.80 |
0.293 |
0.190 |
-0.0789 |
0.664 |
| 1.7 |
0.5140 |
50.10 |
0.293 |
0.209 |
-0.1180 |
0.703 |
| 1.8 |
0.4730 |
63.10 |
0.293 |
0.215 |
-0.1300 |
0.715 |
| 1.9 |
0.4040 |
79.40 |
0.335 |
0.210 |
-0.0757 |
0.746 |
| 2.0 |
0.3280 |
100.00 |
0.335 |
0.218 |
-0.0912 |
0.762 |
| 2.1 |
0.2790 |
126.00 |
0.335 |
0.250 |
-0.1550 |
0.825 |
| 2.2 |
0.2230 |
158.00 |
0.335 |
0.317 |
-0.2850 |
0.956 |
| 2.3 |
0.1990 |
200.00 |
0.335 |
0.319 |
-0.2890 |
0.960 |
| 2.4 |
0.1570 |
251.00 |
0.335 |
0.399 |
-0.4460 |
1.120 |
| 2.5 |
0.1290 |
316.00 |
0.335 |
0.451 |
-0.5490 |
1.220 |
| 2.6 |
0.0959 |
398.00 |
0.335 |
0.372 |
-0.3950 |
1.070 |
| 2.7 |
0.0761 |
501.00 |
0.335 |
0.482 |
-0.6090 |
1.280 |
| 2.8 |
0.0512 |
631.00 |
0.335 |
0.903 |
-1.4300 |
2.110 |
| 2.9 |
0.0455 |
794.00 |
0.335 |
1.220 |
-2.0500 |
2.720 |
| 3.0 |
0.0340 |
1000.00 |
0.335 |
0.968 |
-1.5600 |
2.230 |
| 3.1 |
0.0239 |
1260.00 |
0.335 |
0.928 |
-1.4800 |
2.150 |
| 3.2 |
0.0239 |
1580.00 |
0.335 |
0.928 |
-1.4800 |
2.150 |
| 3.3 |
0.0239 |
2000.00 |
0.335 |
0.928 |
-1.4800 |
2.150 |
IgG3 V1V2 C.1086-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00595 |
0.000929 |
4.13e-03 |
0.00777 |
| 0.1 |
0.9850 |
1.26 |
0.00582 |
0.001010 |
3.84e-03 |
0.00781 |
| 0.2 |
0.9850 |
1.58 |
0.00582 |
0.001010 |
3.84e-03 |
0.00781 |
| 0.3 |
0.9850 |
2.00 |
0.00582 |
0.001010 |
3.84e-03 |
0.00781 |
| 0.4 |
0.9790 |
2.51 |
0.00582 |
0.001020 |
3.83e-03 |
0.00782 |
| 0.5 |
0.9780 |
3.16 |
0.00582 |
0.001020 |
3.83e-03 |
0.00782 |
| 0.6 |
0.9780 |
3.98 |
0.00582 |
0.001020 |
3.83e-03 |
0.00782 |
| 0.7 |
0.9720 |
5.01 |
0.00582 |
0.001030 |
3.81e-03 |
0.00783 |
| 0.8 |
0.9640 |
6.31 |
0.00582 |
0.001030 |
3.80e-03 |
0.00785 |
| 0.9 |
0.9640 |
7.94 |
0.00582 |
0.001030 |
3.80e-03 |
0.00785 |
| 1.0 |
0.9580 |
10.00 |
0.00582 |
0.001040 |
3.79e-03 |
0.00786 |
| 1.1 |
0.9490 |
12.60 |
0.00582 |
0.001050 |
3.77e-03 |
0.00788 |
| 1.2 |
0.9450 |
15.80 |
0.00582 |
0.001040 |
3.79e-03 |
0.00786 |
| 1.3 |
0.9450 |
20.00 |
0.00582 |
0.001020 |
3.82e-03 |
0.00783 |
| 1.4 |
0.9380 |
25.10 |
0.00582 |
0.001030 |
3.81e-03 |
0.00784 |
| 1.5 |
0.9190 |
31.60 |
0.00582 |
0.001040 |
3.79e-03 |
0.00785 |
| 1.6 |
0.9050 |
39.80 |
0.00582 |
0.001040 |
3.79e-03 |
0.00785 |
| 1.7 |
0.8820 |
50.10 |
0.00582 |
0.001070 |
3.73e-03 |
0.00792 |
| 1.8 |
0.8640 |
63.10 |
0.00582 |
0.001050 |
3.76e-03 |
0.00788 |
| 1.9 |
0.8640 |
79.40 |
0.00582 |
0.001050 |
3.76e-03 |
0.00788 |
| 2.0 |
0.8310 |
100.00 |
0.00582 |
0.001080 |
3.72e-03 |
0.00793 |
| 2.1 |
0.7930 |
126.00 |
0.00582 |
0.001070 |
3.73e-03 |
0.00792 |
| 2.2 |
0.7390 |
158.00 |
0.00582 |
0.001110 |
3.66e-03 |
0.00799 |
| 2.3 |
0.6760 |
200.00 |
0.00582 |
0.001190 |
3.49e-03 |
0.00816 |
| 2.4 |
0.6350 |
251.00 |
0.00582 |
0.001260 |
3.36e-03 |
0.00829 |
| 2.5 |
0.5740 |
316.00 |
0.00582 |
0.001390 |
3.10e-03 |
0.00855 |
| 2.6 |
0.5150 |
398.00 |
0.00582 |
0.001410 |
3.06e-03 |
0.00859 |
| 2.7 |
0.4440 |
501.00 |
0.00582 |
0.001590 |
2.71e-03 |
0.00894 |
| 2.8 |
0.3620 |
631.00 |
0.00582 |
0.001890 |
2.12e-03 |
0.00953 |
| 2.9 |
0.2910 |
794.00 |
0.00582 |
0.002230 |
1.45e-03 |
0.01020 |
| 3.0 |
0.2470 |
1000.00 |
0.00582 |
0.002570 |
7.95e-04 |
0.01090 |
| 3.1 |
0.1980 |
1260.00 |
0.00582 |
0.003020 |
-8.86e-05 |
0.01170 |
| 3.2 |
0.1450 |
1580.00 |
0.00582 |
0.003330 |
-7.10e-04 |
0.01240 |
| 3.3 |
0.1130 |
2000.00 |
0.00582 |
0.003740 |
-1.50e-03 |
0.01310 |
| 3.4 |
0.0892 |
2510.00 |
0.00582 |
0.004910 |
-3.81e-03 |
0.01550 |
| 3.5 |
0.0656 |
3160.00 |
0.00582 |
0.007050 |
-8.00e-03 |
0.01960 |
| 3.6 |
0.0552 |
3980.00 |
0.00582 |
0.005750 |
-5.44e-03 |
0.01710 |
| 3.7 |
0.0398 |
5010.00 |
0.00582 |
0.008030 |
-9.91e-03 |
0.02160 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9850 |
0.00572 |
0.001010 |
0.003730 |
0.00770 |
| 0.2 |
1.58 |
0.9850 |
0.00572 |
0.001010 |
0.003730 |
0.00770 |
| 0.3 |
2.00 |
0.9850 |
0.00572 |
0.001010 |
0.003730 |
0.00770 |
| 0.4 |
2.51 |
0.9790 |
0.00574 |
0.001020 |
0.003750 |
0.00774 |
| 0.5 |
3.16 |
0.9780 |
0.00575 |
0.001020 |
0.003750 |
0.00774 |
| 0.6 |
3.98 |
0.9780 |
0.00575 |
0.001020 |
0.003750 |
0.00774 |
| 0.7 |
5.01 |
0.9720 |
0.00578 |
0.001030 |
0.003770 |
0.00779 |
| 0.8 |
6.31 |
0.9640 |
0.00582 |
0.001030 |
0.003800 |
0.00785 |
| 0.9 |
7.94 |
0.9640 |
0.00582 |
0.001030 |
0.003800 |
0.00785 |
| 1.0 |
10.00 |
0.9580 |
0.00586 |
0.001040 |
0.003820 |
0.00790 |
| 1.1 |
12.60 |
0.9490 |
0.00592 |
0.001050 |
0.003860 |
0.00797 |
| 1.2 |
15.80 |
0.9450 |
0.00578 |
0.001040 |
0.003750 |
0.00782 |
| 1.3 |
20.00 |
0.9450 |
0.00563 |
0.001020 |
0.003630 |
0.00763 |
| 1.4 |
25.10 |
0.9380 |
0.00567 |
0.001030 |
0.003650 |
0.00768 |
| 1.5 |
31.60 |
0.9190 |
0.00563 |
0.001040 |
0.003600 |
0.00766 |
| 1.6 |
39.80 |
0.9050 |
0.00555 |
0.001040 |
0.003520 |
0.00758 |
| 1.7 |
50.10 |
0.8820 |
0.00572 |
0.001070 |
0.003620 |
0.00781 |
| 1.8 |
63.10 |
0.8640 |
0.00548 |
0.001050 |
0.003420 |
0.00754 |
| 1.9 |
79.40 |
0.8640 |
0.00548 |
0.001050 |
0.003420 |
0.00754 |
| 2.0 |
100.00 |
0.8310 |
0.00551 |
0.001080 |
0.003400 |
0.00762 |
| 2.1 |
126.00 |
0.7930 |
0.00524 |
0.001070 |
0.003140 |
0.00733 |
| 2.2 |
158.00 |
0.7390 |
0.00522 |
0.001110 |
0.003050 |
0.00738 |
| 2.3 |
200.00 |
0.6760 |
0.00539 |
0.001190 |
0.003050 |
0.00773 |
| 2.4 |
251.00 |
0.6350 |
0.00568 |
0.001260 |
0.003220 |
0.00815 |
| 2.5 |
316.00 |
0.5740 |
0.00622 |
0.001390 |
0.003500 |
0.00894 |
| 2.6 |
398.00 |
0.5150 |
0.00583 |
0.001410 |
0.003060 |
0.00860 |
| 2.7 |
501.00 |
0.4440 |
0.00606 |
0.001590 |
0.002950 |
0.00918 |
| 2.8 |
631.00 |
0.3620 |
0.00672 |
0.001890 |
0.003010 |
0.01040 |
| 2.9 |
794.00 |
0.2910 |
0.00730 |
0.002230 |
0.002930 |
0.01170 |
| 3.0 |
1000.00 |
0.2470 |
0.00726 |
0.002570 |
0.002240 |
0.01230 |
| 3.1 |
1260.00 |
0.1980 |
0.00858 |
0.003020 |
0.002660 |
0.01450 |
| 3.2 |
1580.00 |
0.1450 |
0.00774 |
0.003330 |
0.001210 |
0.01430 |
| 3.3 |
2000.00 |
0.1130 |
0.00855 |
0.003740 |
0.001230 |
0.01590 |
| 3.4 |
2510.00 |
0.0892 |
0.01010 |
0.004910 |
0.000497 |
0.01980 |
| 3.5 |
3160.00 |
0.0656 |
0.01290 |
0.007050 |
-0.000889 |
0.02680 |
| 3.6 |
3980.00 |
0.0552 |
0.00861 |
0.005750 |
-0.002650 |
0.01990 |
| 3.7 |
5010.00 |
0.0398 |
0.01170 |
0.008030 |
-0.004020 |
0.02740 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.228 |
0.164 |
-0.0942 |
0.549 |
| 0.1 |
0.9850 |
1.26 |
0.244 |
0.171 |
-0.0911 |
0.579 |
| 0.2 |
0.9850 |
1.58 |
0.244 |
0.171 |
-0.0911 |
0.579 |
| 0.3 |
0.9850 |
2.00 |
0.244 |
0.171 |
-0.0911 |
0.579 |
| 0.4 |
0.9790 |
2.51 |
0.244 |
0.171 |
-0.0919 |
0.579 |
| 0.5 |
0.9780 |
3.16 |
0.244 |
0.171 |
-0.0922 |
0.580 |
| 0.6 |
0.9780 |
3.98 |
0.244 |
0.171 |
-0.0922 |
0.580 |
| 0.7 |
0.9720 |
5.01 |
0.244 |
0.172 |
-0.0935 |
0.581 |
| 0.8 |
0.9640 |
6.31 |
0.244 |
0.173 |
-0.0952 |
0.583 |
| 0.9 |
0.9640 |
7.94 |
0.244 |
0.173 |
-0.0952 |
0.583 |
| 1.0 |
0.9580 |
10.00 |
0.244 |
0.174 |
-0.0963 |
0.584 |
| 1.1 |
0.9490 |
12.60 |
0.244 |
0.175 |
-0.0984 |
0.586 |
| 1.2 |
0.9450 |
15.80 |
0.244 |
0.173 |
-0.0960 |
0.584 |
| 1.3 |
0.9450 |
20.00 |
0.244 |
0.172 |
-0.0929 |
0.580 |
| 1.4 |
0.9380 |
25.10 |
0.244 |
0.172 |
-0.0943 |
0.582 |
| 1.5 |
0.9190 |
31.60 |
0.244 |
0.173 |
-0.0957 |
0.583 |
| 1.6 |
0.9050 |
39.80 |
0.244 |
0.173 |
-0.0956 |
0.583 |
| 1.7 |
0.8820 |
50.10 |
0.244 |
0.177 |
-0.1020 |
0.590 |
| 1.8 |
0.8640 |
63.10 |
0.244 |
0.175 |
-0.0987 |
0.586 |
| 1.9 |
0.8640 |
79.40 |
0.244 |
0.175 |
-0.0987 |
0.586 |
| 2.0 |
0.8310 |
100.00 |
0.244 |
0.177 |
-0.1030 |
0.591 |
| 2.1 |
0.7930 |
126.00 |
0.244 |
0.177 |
-0.1020 |
0.590 |
| 2.2 |
0.7390 |
158.00 |
0.244 |
0.180 |
-0.1100 |
0.597 |
| 2.3 |
0.6760 |
200.00 |
0.244 |
0.189 |
-0.1280 |
0.615 |
| 2.4 |
0.6350 |
251.00 |
0.244 |
0.197 |
-0.1420 |
0.629 |
| 2.5 |
0.5740 |
316.00 |
0.244 |
0.211 |
-0.1690 |
0.657 |
| 2.6 |
0.5150 |
398.00 |
0.244 |
0.213 |
-0.1740 |
0.662 |
| 2.7 |
0.4440 |
501.00 |
0.244 |
0.233 |
-0.2140 |
0.701 |
| 2.8 |
0.3620 |
631.00 |
0.244 |
0.268 |
-0.2820 |
0.770 |
| 2.9 |
0.2910 |
794.00 |
0.244 |
0.309 |
-0.3630 |
0.850 |
| 3.0 |
0.2470 |
1000.00 |
0.244 |
0.351 |
-0.4430 |
0.931 |
| 3.1 |
0.1980 |
1260.00 |
0.244 |
0.407 |
-0.5530 |
1.040 |
| 3.2 |
0.1450 |
1580.00 |
0.244 |
0.446 |
-0.6310 |
1.120 |
| 3.3 |
0.1130 |
2000.00 |
0.244 |
0.497 |
-0.7310 |
1.220 |
| 3.4 |
0.0892 |
2510.00 |
0.244 |
0.647 |
-1.0200 |
1.510 |
| 3.5 |
0.0656 |
3160.00 |
0.244 |
0.922 |
-1.5600 |
2.050 |
| 3.6 |
0.0552 |
3980.00 |
0.244 |
0.754 |
-1.2300 |
1.720 |
| 3.7 |
0.0398 |
5010.00 |
0.244 |
1.050 |
-1.8100 |
2.300 |
IgG_V1V2_CaseA2_elisa
Monotone

| -0.903 |
1.0000 |
0.125 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| -0.803 |
0.9790 |
0.157 |
0.00590 |
0.001040 |
0.003870 |
0.00793 |
| -0.703 |
0.9160 |
0.198 |
0.00569 |
0.001050 |
0.003640 |
0.00774 |
| -0.603 |
0.7770 |
0.249 |
0.00558 |
0.001130 |
0.003380 |
0.00779 |
| -0.503 |
0.6720 |
0.314 |
0.00454 |
0.001070 |
0.002450 |
0.00664 |
| -0.403 |
0.4790 |
0.395 |
0.00454 |
0.001300 |
0.002000 |
0.00708 |
| -0.303 |
0.3360 |
0.498 |
0.00374 |
0.001450 |
0.000906 |
0.00658 |
| -0.203 |
0.2160 |
0.626 |
0.00275 |
0.001350 |
0.000109 |
0.00539 |
| -0.103 |
0.0986 |
0.789 |
0.00275 |
0.001880 |
-0.000932 |
0.00643 |
Not Monotone

| -0.903 |
0.125 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| -0.803 |
0.157 |
0.9790 |
0.00590 |
0.001040 |
0.003870 |
0.00793 |
| -0.703 |
0.198 |
0.9160 |
0.00569 |
0.001050 |
0.003640 |
0.00774 |
| -0.603 |
0.249 |
0.7770 |
0.00558 |
0.001130 |
0.003380 |
0.00779 |
| -0.503 |
0.314 |
0.6720 |
0.00450 |
0.001070 |
0.002410 |
0.00660 |
| -0.403 |
0.395 |
0.4790 |
0.00459 |
0.001300 |
0.002050 |
0.00713 |
| -0.303 |
0.498 |
0.3360 |
0.00374 |
0.001450 |
0.000906 |
0.00658 |
| -0.203 |
0.626 |
0.2160 |
0.00250 |
0.001350 |
-0.000133 |
0.00514 |
| -0.103 |
0.789 |
0.0986 |
0.00299 |
0.001880 |
-0.000690 |
0.00667 |
Vaccine efficacy (monotone)

| -0.903 |
1.0000 |
0.125 |
0.228 |
0.164 |
-0.0942 |
0.549 |
| -0.803 |
0.9790 |
0.157 |
0.234 |
0.174 |
-0.1080 |
0.575 |
| -0.703 |
0.9160 |
0.198 |
0.261 |
0.173 |
-0.0773 |
0.600 |
| -0.603 |
0.7770 |
0.249 |
0.275 |
0.180 |
-0.0772 |
0.627 |
| -0.503 |
0.6720 |
0.314 |
0.410 |
0.163 |
0.0910 |
0.729 |
| -0.403 |
0.4790 |
0.395 |
0.410 |
0.189 |
0.0406 |
0.780 |
| -0.303 |
0.3360 |
0.498 |
0.514 |
0.201 |
0.1210 |
0.907 |
| -0.203 |
0.2160 |
0.626 |
0.643 |
0.182 |
0.2860 |
1.000 |
| -0.103 |
0.0986 |
0.789 |
0.643 |
0.249 |
0.1550 |
1.130 |
IgG_gp70.V1V2CaseA2
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| 0.1 |
0.9950 |
1.26 |
0.00585 |
0.001020 |
0.003850 |
0.00785 |
| 0.2 |
0.9950 |
1.58 |
0.00585 |
0.001020 |
0.003850 |
0.00785 |
| 0.3 |
0.9950 |
2.00 |
0.00585 |
0.001020 |
0.003850 |
0.00785 |
| 0.4 |
0.9930 |
2.51 |
0.00585 |
0.001020 |
0.003850 |
0.00786 |
| 0.5 |
0.9930 |
3.16 |
0.00585 |
0.001020 |
0.003850 |
0.00786 |
| 0.6 |
0.9840 |
3.98 |
0.00585 |
0.001030 |
0.003830 |
0.00787 |
| 0.7 |
0.9840 |
5.01 |
0.00585 |
0.001030 |
0.003830 |
0.00787 |
| 0.8 |
0.9840 |
6.31 |
0.00585 |
0.001030 |
0.003830 |
0.00787 |
| 0.9 |
0.9840 |
7.94 |
0.00585 |
0.001030 |
0.003830 |
0.00787 |
| 1.0 |
0.9770 |
10.00 |
0.00585 |
0.001040 |
0.003820 |
0.00788 |
| 1.1 |
0.9700 |
12.60 |
0.00580 |
0.001030 |
0.003780 |
0.00782 |
| 1.2 |
0.9640 |
15.80 |
0.00569 |
0.001020 |
0.003690 |
0.00769 |
| 1.3 |
0.9580 |
20.00 |
0.00557 |
0.001010 |
0.003590 |
0.00755 |
| 1.4 |
0.9450 |
25.10 |
0.00550 |
0.001010 |
0.003520 |
0.00747 |
| 1.5 |
0.9290 |
31.60 |
0.00549 |
0.001010 |
0.003500 |
0.00748 |
| 1.6 |
0.9200 |
39.80 |
0.00549 |
0.001020 |
0.003490 |
0.00749 |
| 1.7 |
0.9110 |
50.10 |
0.00549 |
0.001030 |
0.003460 |
0.00752 |
| 1.8 |
0.8930 |
63.10 |
0.00519 |
0.001010 |
0.003220 |
0.00716 |
| 1.9 |
0.8530 |
79.40 |
0.00513 |
0.001010 |
0.003140 |
0.00712 |
| 2.0 |
0.8040 |
100.00 |
0.00513 |
0.001060 |
0.003050 |
0.00720 |
| 2.1 |
0.7400 |
126.00 |
0.00481 |
0.001040 |
0.002770 |
0.00685 |
| 2.2 |
0.6750 |
158.00 |
0.00481 |
0.001110 |
0.002650 |
0.00698 |
| 2.3 |
0.6450 |
200.00 |
0.00481 |
0.001130 |
0.002590 |
0.00704 |
| 2.4 |
0.5840 |
251.00 |
0.00460 |
0.001130 |
0.002390 |
0.00681 |
| 2.5 |
0.5120 |
316.00 |
0.00460 |
0.001280 |
0.002090 |
0.00711 |
| 2.6 |
0.4520 |
398.00 |
0.00438 |
0.001280 |
0.001870 |
0.00689 |
| 2.7 |
0.3730 |
501.00 |
0.00396 |
0.001300 |
0.001400 |
0.00651 |
| 2.8 |
0.2950 |
631.00 |
0.00309 |
0.001270 |
0.000607 |
0.00557 |
| 2.9 |
0.2310 |
794.00 |
0.00293 |
0.001130 |
0.000711 |
0.00515 |
| 3.0 |
0.1630 |
1000.00 |
0.00293 |
0.001970 |
-0.000929 |
0.00679 |
| 3.1 |
0.1400 |
1260.00 |
0.00293 |
0.001580 |
-0.000160 |
0.00602 |
| 3.2 |
0.0888 |
1580.00 |
0.00293 |
0.002250 |
-0.001470 |
0.00733 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
3.92e-03 |
0.00797 |
| 0.1 |
1.26 |
0.9950 |
0.00582 |
0.001020 |
3.82e-03 |
0.00782 |
| 0.2 |
1.58 |
0.9950 |
0.00582 |
0.001020 |
3.82e-03 |
0.00782 |
| 0.3 |
2.00 |
0.9950 |
0.00582 |
0.001020 |
3.82e-03 |
0.00782 |
| 0.4 |
2.51 |
0.9930 |
0.00583 |
0.001020 |
3.82e-03 |
0.00783 |
| 0.5 |
3.16 |
0.9930 |
0.00583 |
0.001020 |
3.82e-03 |
0.00783 |
| 0.6 |
3.98 |
0.9840 |
0.00587 |
0.001030 |
3.85e-03 |
0.00789 |
| 0.7 |
5.01 |
0.9840 |
0.00587 |
0.001030 |
3.85e-03 |
0.00789 |
| 0.8 |
6.31 |
0.9840 |
0.00587 |
0.001030 |
3.85e-03 |
0.00789 |
| 0.9 |
7.94 |
0.9840 |
0.00587 |
0.001030 |
3.85e-03 |
0.00789 |
| 1.0 |
10.00 |
0.9770 |
0.00591 |
0.001040 |
3.88e-03 |
0.00794 |
| 1.1 |
12.60 |
0.9700 |
0.00580 |
0.001030 |
3.78e-03 |
0.00782 |
| 1.2 |
15.80 |
0.9640 |
0.00569 |
0.001020 |
3.69e-03 |
0.00769 |
| 1.3 |
20.00 |
0.9580 |
0.00557 |
0.001010 |
3.59e-03 |
0.00755 |
| 1.4 |
25.10 |
0.9450 |
0.00550 |
0.001010 |
3.52e-03 |
0.00747 |
| 1.5 |
31.60 |
0.9290 |
0.00544 |
0.001010 |
3.46e-03 |
0.00743 |
| 1.6 |
39.80 |
0.9200 |
0.00548 |
0.001020 |
3.48e-03 |
0.00748 |
| 1.7 |
50.10 |
0.9110 |
0.00554 |
0.001030 |
3.52e-03 |
0.00757 |
| 1.8 |
63.10 |
0.8930 |
0.00519 |
0.001010 |
3.22e-03 |
0.00716 |
| 1.9 |
79.40 |
0.8530 |
0.00507 |
0.001010 |
3.08e-03 |
0.00706 |
| 2.0 |
100.00 |
0.8040 |
0.00519 |
0.001060 |
3.11e-03 |
0.00726 |
| 2.1 |
126.00 |
0.7400 |
0.00475 |
0.001040 |
2.71e-03 |
0.00679 |
| 2.2 |
158.00 |
0.6750 |
0.00484 |
0.001110 |
2.67e-03 |
0.00701 |
| 2.3 |
200.00 |
0.6450 |
0.00485 |
0.001130 |
2.63e-03 |
0.00707 |
| 2.4 |
251.00 |
0.5840 |
0.00440 |
0.001130 |
2.19e-03 |
0.00661 |
| 2.5 |
316.00 |
0.5120 |
0.00481 |
0.001280 |
2.30e-03 |
0.00732 |
| 2.6 |
398.00 |
0.4520 |
0.00438 |
0.001280 |
1.87e-03 |
0.00689 |
| 2.7 |
501.00 |
0.3730 |
0.00396 |
0.001300 |
1.40e-03 |
0.00651 |
| 2.8 |
631.00 |
0.2950 |
0.00309 |
0.001270 |
6.07e-04 |
0.00557 |
| 2.9 |
794.00 |
0.2310 |
0.00213 |
0.001130 |
-8.53e-05 |
0.00435 |
| 3.0 |
1000.00 |
0.1630 |
0.00343 |
0.001970 |
-4.32e-04 |
0.00729 |
| 3.1 |
1260.00 |
0.1400 |
0.00258 |
0.001580 |
-5.10e-04 |
0.00567 |
| 3.2 |
1580.00 |
0.0888 |
0.00358 |
0.002250 |
-8.24e-04 |
0.00798 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.228 |
0.164 |
-0.09420 |
0.549 |
| 0.1 |
0.9950 |
1.26 |
0.240 |
0.172 |
-0.09700 |
0.577 |
| 0.2 |
0.9950 |
1.58 |
0.240 |
0.172 |
-0.09700 |
0.577 |
| 0.3 |
0.9950 |
2.00 |
0.240 |
0.172 |
-0.09700 |
0.577 |
| 0.4 |
0.9930 |
2.51 |
0.240 |
0.172 |
-0.09730 |
0.578 |
| 0.5 |
0.9930 |
3.16 |
0.240 |
0.172 |
-0.09730 |
0.578 |
| 0.6 |
0.9840 |
3.98 |
0.240 |
0.173 |
-0.09890 |
0.579 |
| 0.7 |
0.9840 |
5.01 |
0.240 |
0.173 |
-0.09890 |
0.579 |
| 0.8 |
0.9840 |
6.31 |
0.240 |
0.173 |
-0.09890 |
0.579 |
| 0.9 |
0.9840 |
7.94 |
0.240 |
0.173 |
-0.09890 |
0.579 |
| 1.0 |
0.9770 |
10.00 |
0.240 |
0.174 |
-0.10000 |
0.581 |
| 1.1 |
0.9700 |
12.60 |
0.247 |
0.172 |
-0.09060 |
0.584 |
| 1.2 |
0.9640 |
15.80 |
0.261 |
0.170 |
-0.07150 |
0.594 |
| 1.3 |
0.9580 |
20.00 |
0.277 |
0.167 |
-0.05110 |
0.605 |
| 1.4 |
0.9450 |
25.10 |
0.286 |
0.167 |
-0.04030 |
0.613 |
| 1.5 |
0.9290 |
31.60 |
0.287 |
0.167 |
-0.04000 |
0.615 |
| 1.6 |
0.9200 |
39.80 |
0.287 |
0.168 |
-0.04150 |
0.616 |
| 1.7 |
0.9110 |
50.10 |
0.287 |
0.169 |
-0.04410 |
0.619 |
| 1.8 |
0.8930 |
63.10 |
0.326 |
0.163 |
0.00665 |
0.645 |
| 1.9 |
0.8530 |
79.40 |
0.334 |
0.163 |
0.01470 |
0.654 |
| 2.0 |
0.8040 |
100.00 |
0.334 |
0.168 |
0.00537 |
0.663 |
| 2.1 |
0.7400 |
126.00 |
0.375 |
0.162 |
0.05650 |
0.693 |
| 2.2 |
0.6750 |
158.00 |
0.375 |
0.170 |
0.04250 |
0.707 |
| 2.3 |
0.6450 |
200.00 |
0.375 |
0.173 |
0.03660 |
0.713 |
| 2.4 |
0.5840 |
251.00 |
0.403 |
0.170 |
0.06940 |
0.736 |
| 2.5 |
0.5120 |
316.00 |
0.403 |
0.187 |
0.03560 |
0.770 |
| 2.6 |
0.4520 |
398.00 |
0.431 |
0.185 |
0.06810 |
0.795 |
| 2.7 |
0.3730 |
501.00 |
0.486 |
0.185 |
0.12400 |
0.848 |
| 2.8 |
0.2950 |
631.00 |
0.599 |
0.174 |
0.25800 |
0.941 |
| 2.9 |
0.2310 |
794.00 |
0.620 |
0.157 |
0.31200 |
0.927 |
| 3.0 |
0.1630 |
1000.00 |
0.620 |
0.261 |
0.10700 |
1.130 |
| 3.1 |
0.1400 |
1260.00 |
0.620 |
0.212 |
0.20400 |
1.030 |
| 3.2 |
0.0888 |
1580.00 |
0.620 |
0.297 |
0.03790 |
1.200 |
IgG_A244D11K169
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00595 |
0.000929 |
0.00413 |
0.00777 |
| 0.1 |
0.9940 |
1.26 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 0.2 |
0.9940 |
1.58 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 0.3 |
0.9940 |
2.00 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 0.4 |
0.9940 |
2.51 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 0.5 |
0.9940 |
3.16 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 0.6 |
0.9940 |
3.98 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 0.7 |
0.9920 |
5.01 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 0.8 |
0.9920 |
6.31 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 0.9 |
0.9920 |
7.94 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 1.0 |
0.9920 |
10.00 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 1.1 |
0.9920 |
12.60 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 1.2 |
0.9920 |
15.80 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 1.3 |
0.9920 |
20.00 |
0.00585 |
0.001020 |
0.00384 |
0.00785 |
| 1.4 |
0.9900 |
25.10 |
0.00585 |
0.001030 |
0.00383 |
0.00786 |
| 1.5 |
0.9900 |
31.60 |
0.00585 |
0.001030 |
0.00383 |
0.00786 |
| 1.6 |
0.9890 |
39.80 |
0.00585 |
0.001030 |
0.00383 |
0.00786 |
| 1.7 |
0.9890 |
50.10 |
0.00585 |
0.001030 |
0.00383 |
0.00786 |
| 1.8 |
0.9880 |
63.10 |
0.00585 |
0.001010 |
0.00386 |
0.00783 |
| 1.9 |
0.9880 |
79.40 |
0.00585 |
0.001010 |
0.00386 |
0.00783 |
| 2.0 |
0.9870 |
100.00 |
0.00585 |
0.001020 |
0.00386 |
0.00784 |
| 2.1 |
0.9870 |
126.00 |
0.00585 |
0.001020 |
0.00386 |
0.00784 |
| 2.2 |
0.9850 |
158.00 |
0.00585 |
0.001020 |
0.00385 |
0.00784 |
| 2.3 |
0.9850 |
200.00 |
0.00585 |
0.001020 |
0.00385 |
0.00784 |
| 2.4 |
0.9850 |
251.00 |
0.00585 |
0.001020 |
0.00385 |
0.00784 |
| 2.5 |
0.9850 |
316.00 |
0.00585 |
0.001020 |
0.00385 |
0.00784 |
| 2.6 |
0.9850 |
398.00 |
0.00585 |
0.001020 |
0.00385 |
0.00784 |
| 2.7 |
0.9850 |
501.00 |
0.00585 |
0.001000 |
0.00388 |
0.00781 |
| 2.8 |
0.9690 |
631.00 |
0.00585 |
0.001020 |
0.00385 |
0.00784 |
| 2.9 |
0.9610 |
794.00 |
0.00585 |
0.001010 |
0.00387 |
0.00782 |
| 3.0 |
0.9520 |
1000.00 |
0.00585 |
0.001000 |
0.00388 |
0.00781 |
| 3.1 |
0.9150 |
1260.00 |
0.00585 |
0.001030 |
0.00383 |
0.00786 |
| 3.2 |
0.8590 |
1580.00 |
0.00585 |
0.001080 |
0.00374 |
0.00796 |
| 3.3 |
0.8030 |
2000.00 |
0.00585 |
0.001100 |
0.00369 |
0.00800 |
| 3.4 |
0.7020 |
2510.00 |
0.00585 |
0.001160 |
0.00357 |
0.00813 |
| 3.5 |
0.5770 |
3160.00 |
0.00585 |
0.001350 |
0.00321 |
0.00849 |
| 3.6 |
0.4180 |
3980.00 |
0.00585 |
0.001700 |
0.00252 |
0.00917 |
| 3.7 |
0.3710 |
5010.00 |
0.00585 |
0.001770 |
0.00237 |
0.00932 |
| 3.8 |
0.2660 |
6310.00 |
0.00585 |
0.002060 |
0.00180 |
0.00989 |
| 3.9 |
0.1340 |
7940.00 |
0.00585 |
0.004570 |
-0.00312 |
0.01480 |
| 4.0 |
0.0839 |
10000.00 |
0.00585 |
0.005760 |
-0.00545 |
0.01710 |
| 4.1 |
0.0476 |
12600.00 |
0.00585 |
0.010400 |
-0.01460 |
0.02630 |
| 4.2 |
0.0252 |
15800.00 |
0.00585 |
0.019300 |
-0.03190 |
0.04360 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.00392 |
0.00797 |
| 0.1 |
1.26 |
0.9940 |
0.00583 |
0.001020 |
0.00382 |
0.00783 |
| 0.2 |
1.58 |
0.9940 |
0.00583 |
0.001020 |
0.00382 |
0.00783 |
| 0.3 |
2.00 |
0.9940 |
0.00583 |
0.001020 |
0.00382 |
0.00783 |
| 0.4 |
2.51 |
0.9940 |
0.00583 |
0.001020 |
0.00382 |
0.00783 |
| 0.5 |
3.16 |
0.9940 |
0.00583 |
0.001020 |
0.00382 |
0.00783 |
| 0.6 |
3.98 |
0.9940 |
0.00583 |
0.001020 |
0.00382 |
0.00783 |
| 0.7 |
5.01 |
0.9920 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 0.8 |
6.31 |
0.9920 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 0.9 |
7.94 |
0.9920 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.0 |
10.00 |
0.9920 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.1 |
12.60 |
0.9920 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.2 |
15.80 |
0.9920 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.3 |
20.00 |
0.9920 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.4 |
25.10 |
0.9900 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.5 |
31.60 |
0.9900 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.6 |
39.80 |
0.9890 |
0.00585 |
0.001030 |
0.00384 |
0.00787 |
| 1.7 |
50.10 |
0.9890 |
0.00585 |
0.001030 |
0.00384 |
0.00787 |
| 1.8 |
63.10 |
0.9880 |
0.00570 |
0.001010 |
0.00372 |
0.00769 |
| 1.9 |
79.40 |
0.9880 |
0.00570 |
0.001010 |
0.00372 |
0.00769 |
| 2.0 |
100.00 |
0.9870 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.1 |
126.00 |
0.9870 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.2 |
158.00 |
0.9850 |
0.00573 |
0.001020 |
0.00373 |
0.00772 |
| 2.3 |
200.00 |
0.9850 |
0.00573 |
0.001020 |
0.00373 |
0.00772 |
| 2.4 |
251.00 |
0.9850 |
0.00573 |
0.001020 |
0.00373 |
0.00772 |
| 2.5 |
316.00 |
0.9850 |
0.00573 |
0.001020 |
0.00373 |
0.00772 |
| 2.6 |
398.00 |
0.9850 |
0.00573 |
0.001020 |
0.00373 |
0.00772 |
| 2.7 |
501.00 |
0.9850 |
0.00559 |
0.001000 |
0.00362 |
0.00755 |
| 2.8 |
631.00 |
0.9690 |
0.00568 |
0.001020 |
0.00368 |
0.00767 |
| 2.9 |
794.00 |
0.9610 |
0.00556 |
0.001010 |
0.00358 |
0.00753 |
| 3.0 |
1000.00 |
0.9520 |
0.00545 |
0.001000 |
0.00349 |
0.00742 |
| 3.1 |
1260.00 |
0.9150 |
0.00552 |
0.001030 |
0.00350 |
0.00754 |
| 3.2 |
1580.00 |
0.8590 |
0.00568 |
0.001080 |
0.00357 |
0.00779 |
| 3.3 |
2000.00 |
0.8030 |
0.00554 |
0.001100 |
0.00339 |
0.00770 |
| 3.4 |
2510.00 |
0.7020 |
0.00545 |
0.001160 |
0.00317 |
0.00773 |
| 3.5 |
3160.00 |
0.5770 |
0.00568 |
0.001350 |
0.00304 |
0.00832 |
| 3.6 |
3980.00 |
0.4180 |
0.00655 |
0.001700 |
0.00322 |
0.00988 |
| 3.7 |
5010.00 |
0.3710 |
0.00645 |
0.001770 |
0.00298 |
0.00992 |
| 3.8 |
6310.00 |
0.2660 |
0.00627 |
0.002060 |
0.00223 |
0.01030 |
| 3.9 |
7940.00 |
0.1340 |
0.01230 |
0.004570 |
0.00331 |
0.02120 |
| 4.0 |
10000.00 |
0.0839 |
0.00970 |
0.005760 |
-0.00160 |
0.02100 |
| 4.1 |
12600.00 |
0.0476 |
0.01520 |
0.010400 |
-0.00526 |
0.03560 |
| 4.2 |
15800.00 |
0.0252 |
0.02460 |
0.019300 |
-0.01320 |
0.06230 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.228 |
0.164 |
-0.0942 |
0.549 |
| 0.1 |
0.9940 |
1.26 |
0.241 |
0.172 |
-0.0965 |
0.578 |
| 0.2 |
0.9940 |
1.58 |
0.241 |
0.172 |
-0.0965 |
0.578 |
| 0.3 |
0.9940 |
2.00 |
0.241 |
0.172 |
-0.0965 |
0.578 |
| 0.4 |
0.9940 |
2.51 |
0.241 |
0.172 |
-0.0965 |
0.578 |
| 0.5 |
0.9940 |
3.16 |
0.241 |
0.172 |
-0.0965 |
0.578 |
| 0.6 |
0.9940 |
3.98 |
0.241 |
0.172 |
-0.0965 |
0.578 |
| 0.7 |
0.9920 |
5.01 |
0.241 |
0.172 |
-0.0968 |
0.579 |
| 0.8 |
0.9920 |
6.31 |
0.241 |
0.172 |
-0.0968 |
0.579 |
| 0.9 |
0.9920 |
7.94 |
0.241 |
0.172 |
-0.0968 |
0.579 |
| 1.0 |
0.9920 |
10.00 |
0.241 |
0.172 |
-0.0968 |
0.579 |
| 1.1 |
0.9920 |
12.60 |
0.241 |
0.172 |
-0.0968 |
0.579 |
| 1.2 |
0.9920 |
15.80 |
0.241 |
0.172 |
-0.0968 |
0.579 |
| 1.3 |
0.9920 |
20.00 |
0.241 |
0.172 |
-0.0968 |
0.579 |
| 1.4 |
0.9900 |
25.10 |
0.241 |
0.172 |
-0.0972 |
0.579 |
| 1.5 |
0.9900 |
31.60 |
0.241 |
0.172 |
-0.0972 |
0.579 |
| 1.6 |
0.9890 |
39.80 |
0.241 |
0.173 |
-0.0975 |
0.579 |
| 1.7 |
0.9890 |
50.10 |
0.241 |
0.173 |
-0.0975 |
0.579 |
| 1.8 |
0.9880 |
63.10 |
0.241 |
0.171 |
-0.0946 |
0.576 |
| 1.9 |
0.9880 |
79.40 |
0.241 |
0.171 |
-0.0946 |
0.576 |
| 2.0 |
0.9870 |
100.00 |
0.241 |
0.171 |
-0.0950 |
0.577 |
| 2.1 |
0.9870 |
126.00 |
0.241 |
0.171 |
-0.0950 |
0.577 |
| 2.2 |
0.9850 |
158.00 |
0.241 |
0.172 |
-0.0954 |
0.577 |
| 2.3 |
0.9850 |
200.00 |
0.241 |
0.172 |
-0.0954 |
0.577 |
| 2.4 |
0.9850 |
251.00 |
0.241 |
0.172 |
-0.0954 |
0.577 |
| 2.5 |
0.9850 |
316.00 |
0.241 |
0.172 |
-0.0954 |
0.577 |
| 2.6 |
0.9850 |
398.00 |
0.241 |
0.172 |
-0.0954 |
0.577 |
| 2.7 |
0.9850 |
501.00 |
0.241 |
0.170 |
-0.0925 |
0.574 |
| 2.8 |
0.9690 |
631.00 |
0.241 |
0.172 |
-0.0955 |
0.577 |
| 2.9 |
0.9610 |
794.00 |
0.241 |
0.171 |
-0.0935 |
0.575 |
| 3.0 |
0.9520 |
1000.00 |
0.241 |
0.170 |
-0.0922 |
0.574 |
| 3.1 |
0.9150 |
1260.00 |
0.241 |
0.173 |
-0.0977 |
0.579 |
| 3.2 |
0.8590 |
1580.00 |
0.241 |
0.178 |
-0.1070 |
0.589 |
| 3.3 |
0.8030 |
2000.00 |
0.241 |
0.180 |
-0.1120 |
0.593 |
| 3.4 |
0.7020 |
2510.00 |
0.241 |
0.187 |
-0.1250 |
0.606 |
| 3.5 |
0.5770 |
3160.00 |
0.241 |
0.206 |
-0.1640 |
0.645 |
| 3.6 |
0.4180 |
3980.00 |
0.241 |
0.246 |
-0.2420 |
0.723 |
| 3.7 |
0.3710 |
5010.00 |
0.241 |
0.255 |
-0.2590 |
0.740 |
| 3.8 |
0.2660 |
6310.00 |
0.241 |
0.289 |
-0.3260 |
0.808 |
| 3.9 |
0.1340 |
7940.00 |
0.241 |
0.604 |
-0.9430 |
1.420 |
| 4.0 |
0.0839 |
10000.00 |
0.241 |
0.756 |
-1.2400 |
1.720 |
| 4.1 |
0.0476 |
12600.00 |
0.241 |
1.360 |
-2.4200 |
2.910 |
| 4.2 |
0.0252 |
15800.00 |
0.241 |
2.500 |
-4.6700 |
5.150 |
IgG_gp70ClAEV1V2
Monotone

| 0.0 |
1.000 |
1.00 |
0.00597 |
0.000929 |
0.00415 |
0.00779 |
| 0.1 |
0.997 |
1.26 |
0.00597 |
0.001030 |
0.00394 |
0.00800 |
| 0.2 |
0.997 |
1.58 |
0.00597 |
0.001030 |
0.00394 |
0.00800 |
| 0.3 |
0.997 |
2.00 |
0.00597 |
0.001030 |
0.00394 |
0.00800 |
| 0.4 |
0.995 |
2.51 |
0.00597 |
0.001040 |
0.00394 |
0.00800 |
| 0.5 |
0.994 |
3.16 |
0.00597 |
0.001040 |
0.00394 |
0.00800 |
| 0.6 |
0.992 |
3.98 |
0.00597 |
0.001040 |
0.00393 |
0.00801 |
| 0.7 |
0.992 |
5.01 |
0.00597 |
0.001040 |
0.00393 |
0.00801 |
| 0.8 |
0.992 |
6.31 |
0.00597 |
0.001040 |
0.00393 |
0.00801 |
| 0.9 |
0.992 |
7.94 |
0.00597 |
0.001040 |
0.00393 |
0.00801 |
| 1.0 |
0.992 |
10.00 |
0.00597 |
0.001040 |
0.00393 |
0.00801 |
| 1.1 |
0.992 |
12.60 |
0.00597 |
0.001040 |
0.00393 |
0.00801 |
| 1.2 |
0.992 |
15.80 |
0.00597 |
0.001040 |
0.00393 |
0.00801 |
| 1.3 |
0.992 |
20.00 |
0.00584 |
0.001020 |
0.00383 |
0.00785 |
| 1.4 |
0.992 |
25.10 |
0.00584 |
0.001020 |
0.00383 |
0.00785 |
| 1.5 |
0.992 |
31.60 |
0.00584 |
0.001020 |
0.00383 |
0.00785 |
| 1.6 |
0.992 |
39.80 |
0.00584 |
0.001020 |
0.00383 |
0.00785 |
| 1.7 |
0.990 |
50.10 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.8 |
0.990 |
63.10 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.9 |
0.990 |
79.40 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.0 |
0.990 |
100.00 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.1 |
0.990 |
126.00 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.2 |
0.990 |
158.00 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.3 |
0.990 |
200.00 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.4 |
0.989 |
251.00 |
0.00584 |
0.001030 |
0.00383 |
0.00786 |
| 2.5 |
0.987 |
316.00 |
0.00584 |
0.001030 |
0.00382 |
0.00786 |
| 2.6 |
0.987 |
398.00 |
0.00573 |
0.001020 |
0.00374 |
0.00772 |
| 2.7 |
0.987 |
501.00 |
0.00573 |
0.001020 |
0.00374 |
0.00772 |
| 2.8 |
0.987 |
631.00 |
0.00573 |
0.001020 |
0.00374 |
0.00772 |
| 2.9 |
0.981 |
794.00 |
0.00573 |
0.001020 |
0.00373 |
0.00773 |
| 3.0 |
0.981 |
1000.00 |
0.00573 |
0.001020 |
0.00373 |
0.00773 |
| 3.1 |
0.981 |
1260.00 |
0.00562 |
0.001010 |
0.00365 |
0.00759 |
| 3.2 |
0.976 |
1580.00 |
0.00562 |
0.001010 |
0.00364 |
0.00760 |
| 3.3 |
0.976 |
2000.00 |
0.00549 |
0.000996 |
0.00354 |
0.00744 |
| 3.4 |
0.967 |
2510.00 |
0.00540 |
0.000990 |
0.00346 |
0.00735 |
| 3.5 |
0.967 |
3160.00 |
0.00540 |
0.000990 |
0.00346 |
0.00735 |
| 3.6 |
0.963 |
3980.00 |
0.00540 |
0.000994 |
0.00346 |
0.00735 |
| 3.7 |
0.963 |
5010.00 |
0.00515 |
0.000963 |
0.00326 |
0.00704 |
| 3.8 |
0.951 |
6310.00 |
0.00515 |
0.000973 |
0.00324 |
0.00706 |
| 3.9 |
0.927 |
7940.00 |
0.00512 |
0.000969 |
0.00322 |
0.00702 |
| 4.0 |
0.922 |
10000.00 |
0.00512 |
0.000956 |
0.00325 |
0.00699 |
| 4.1 |
0.872 |
12600.00 |
0.00512 |
0.000998 |
0.00317 |
0.00708 |
| 4.2 |
0.807 |
15800.00 |
0.00512 |
0.001070 |
0.00303 |
0.00721 |
| 4.3 |
0.722 |
20000.00 |
0.00512 |
0.001150 |
0.00287 |
0.00738 |
| 4.4 |
0.408 |
25100.00 |
0.00512 |
0.001570 |
0.00204 |
0.00820 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00595 |
0.000929 |
0.00392 |
0.00797 |
| 0.1 |
1.26 |
0.997 |
0.00596 |
0.001030 |
0.00393 |
0.00799 |
| 0.2 |
1.58 |
0.997 |
0.00596 |
0.001030 |
0.00393 |
0.00799 |
| 0.3 |
2.00 |
0.997 |
0.00596 |
0.001030 |
0.00393 |
0.00799 |
| 0.4 |
2.51 |
0.995 |
0.00596 |
0.001040 |
0.00393 |
0.00800 |
| 0.5 |
3.16 |
0.994 |
0.00597 |
0.001040 |
0.00394 |
0.00801 |
| 0.6 |
3.98 |
0.992 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 0.7 |
5.01 |
0.992 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 0.8 |
6.31 |
0.992 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 0.9 |
7.94 |
0.992 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 1.0 |
10.00 |
0.992 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 1.1 |
12.60 |
0.992 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 1.2 |
15.80 |
0.992 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 1.3 |
20.00 |
0.992 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.4 |
25.10 |
0.992 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.5 |
31.60 |
0.992 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.6 |
39.80 |
0.992 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.7 |
50.10 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.8 |
63.10 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.9 |
79.40 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.0 |
100.00 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.1 |
126.00 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.2 |
158.00 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.3 |
200.00 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.4 |
251.00 |
0.989 |
0.00586 |
0.001030 |
0.00384 |
0.00787 |
| 2.5 |
316.00 |
0.987 |
0.00586 |
0.001030 |
0.00385 |
0.00788 |
| 2.6 |
398.00 |
0.987 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.7 |
501.00 |
0.987 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.8 |
631.00 |
0.987 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.9 |
794.00 |
0.981 |
0.00575 |
0.001020 |
0.00374 |
0.00775 |
| 3.0 |
1000.00 |
0.981 |
0.00575 |
0.001020 |
0.00374 |
0.00775 |
| 3.1 |
1260.00 |
0.981 |
0.00560 |
0.001010 |
0.00363 |
0.00758 |
| 3.2 |
1580.00 |
0.976 |
0.00564 |
0.001010 |
0.00366 |
0.00762 |
| 3.3 |
2000.00 |
0.976 |
0.00549 |
0.000996 |
0.00354 |
0.00744 |
| 3.4 |
2510.00 |
0.967 |
0.00540 |
0.000990 |
0.00346 |
0.00734 |
| 3.5 |
3160.00 |
0.967 |
0.00540 |
0.000990 |
0.00346 |
0.00734 |
| 3.6 |
3980.00 |
0.963 |
0.00542 |
0.000994 |
0.00347 |
0.00737 |
| 3.7 |
5010.00 |
0.963 |
0.00512 |
0.000963 |
0.00324 |
0.00701 |
| 3.8 |
6310.00 |
0.951 |
0.00518 |
0.000973 |
0.00327 |
0.00708 |
| 3.9 |
7940.00 |
0.927 |
0.00501 |
0.000969 |
0.00311 |
0.00691 |
| 4.0 |
10000.00 |
0.922 |
0.00487 |
0.000956 |
0.00300 |
0.00674 |
| 4.1 |
12600.00 |
0.872 |
0.00499 |
0.000998 |
0.00303 |
0.00694 |
| 4.2 |
15800.00 |
0.807 |
0.00522 |
0.001070 |
0.00313 |
0.00730 |
| 4.3 |
20000.00 |
0.722 |
0.00541 |
0.001150 |
0.00316 |
0.00767 |
| 4.4 |
25100.00 |
0.408 |
0.00534 |
0.001570 |
0.00226 |
0.00842 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.225 |
0.164 |
-0.09750 |
0.547 |
| 0.1 |
0.997 |
1.26 |
0.225 |
0.175 |
-0.11800 |
0.567 |
| 0.2 |
0.997 |
1.58 |
0.225 |
0.175 |
-0.11800 |
0.567 |
| 0.3 |
0.997 |
2.00 |
0.225 |
0.175 |
-0.11800 |
0.567 |
| 0.4 |
0.995 |
2.51 |
0.225 |
0.175 |
-0.11800 |
0.568 |
| 0.5 |
0.994 |
3.16 |
0.225 |
0.175 |
-0.11800 |
0.568 |
| 0.6 |
0.992 |
3.98 |
0.225 |
0.175 |
-0.11900 |
0.568 |
| 0.7 |
0.992 |
5.01 |
0.225 |
0.175 |
-0.11900 |
0.568 |
| 0.8 |
0.992 |
6.31 |
0.225 |
0.175 |
-0.11900 |
0.568 |
| 0.9 |
0.992 |
7.94 |
0.225 |
0.175 |
-0.11900 |
0.568 |
| 1.0 |
0.992 |
10.00 |
0.225 |
0.175 |
-0.11900 |
0.568 |
| 1.1 |
0.992 |
12.60 |
0.225 |
0.175 |
-0.11900 |
0.568 |
| 1.2 |
0.992 |
15.80 |
0.225 |
0.175 |
-0.11900 |
0.568 |
| 1.3 |
0.992 |
20.00 |
0.241 |
0.172 |
-0.09620 |
0.579 |
| 1.4 |
0.992 |
25.10 |
0.241 |
0.172 |
-0.09620 |
0.579 |
| 1.5 |
0.992 |
31.60 |
0.241 |
0.172 |
-0.09620 |
0.579 |
| 1.6 |
0.992 |
39.80 |
0.241 |
0.172 |
-0.09620 |
0.579 |
| 1.7 |
0.990 |
50.10 |
0.241 |
0.172 |
-0.09660 |
0.579 |
| 1.8 |
0.990 |
63.10 |
0.241 |
0.172 |
-0.09660 |
0.579 |
| 1.9 |
0.990 |
79.40 |
0.241 |
0.172 |
-0.09660 |
0.579 |
| 2.0 |
0.990 |
100.00 |
0.241 |
0.172 |
-0.09660 |
0.579 |
| 2.1 |
0.990 |
126.00 |
0.241 |
0.172 |
-0.09660 |
0.579 |
| 2.2 |
0.990 |
158.00 |
0.241 |
0.172 |
-0.09660 |
0.579 |
| 2.3 |
0.990 |
200.00 |
0.241 |
0.172 |
-0.09660 |
0.579 |
| 2.4 |
0.989 |
251.00 |
0.241 |
0.173 |
-0.09710 |
0.580 |
| 2.5 |
0.987 |
316.00 |
0.241 |
0.173 |
-0.09740 |
0.580 |
| 2.6 |
0.987 |
398.00 |
0.256 |
0.170 |
-0.07710 |
0.589 |
| 2.7 |
0.987 |
501.00 |
0.256 |
0.170 |
-0.07710 |
0.589 |
| 2.8 |
0.987 |
631.00 |
0.256 |
0.170 |
-0.07710 |
0.589 |
| 2.9 |
0.981 |
794.00 |
0.256 |
0.171 |
-0.07820 |
0.590 |
| 3.0 |
0.981 |
1000.00 |
0.256 |
0.171 |
-0.07820 |
0.590 |
| 3.1 |
0.981 |
1260.00 |
0.270 |
0.168 |
-0.05870 |
0.599 |
| 3.2 |
0.976 |
1580.00 |
0.270 |
0.168 |
-0.05960 |
0.600 |
| 3.3 |
0.976 |
2000.00 |
0.287 |
0.165 |
-0.03710 |
0.611 |
| 3.4 |
0.967 |
2510.00 |
0.298 |
0.164 |
-0.02250 |
0.619 |
| 3.5 |
0.967 |
3160.00 |
0.298 |
0.164 |
-0.02250 |
0.619 |
| 3.6 |
0.963 |
3980.00 |
0.298 |
0.164 |
-0.02330 |
0.620 |
| 3.7 |
0.963 |
5010.00 |
0.331 |
0.158 |
0.02180 |
0.641 |
| 3.8 |
0.951 |
6310.00 |
0.331 |
0.159 |
0.01970 |
0.643 |
| 3.9 |
0.927 |
7940.00 |
0.335 |
0.158 |
0.02490 |
0.645 |
| 4.0 |
0.922 |
10000.00 |
0.335 |
0.157 |
0.02770 |
0.642 |
| 4.1 |
0.872 |
12600.00 |
0.335 |
0.161 |
0.01920 |
0.651 |
| 4.2 |
0.807 |
15800.00 |
0.335 |
0.168 |
0.00509 |
0.665 |
| 4.3 |
0.722 |
20000.00 |
0.335 |
0.177 |
-0.01280 |
0.683 |
| 4.4 |
0.408 |
25100.00 |
0.335 |
0.225 |
-0.10700 |
0.777 |
IgG_gp70V1V2A
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| 0.1 |
0.9920 |
1.26 |
0.00590 |
0.001020 |
0.003890 |
0.00791 |
| 0.2 |
0.9920 |
1.58 |
0.00590 |
0.001020 |
0.003890 |
0.00791 |
| 0.3 |
0.9920 |
2.00 |
0.00590 |
0.001020 |
0.003890 |
0.00791 |
| 0.4 |
0.9900 |
2.51 |
0.00590 |
0.001030 |
0.003890 |
0.00791 |
| 0.5 |
0.9880 |
3.16 |
0.00590 |
0.001030 |
0.003890 |
0.00792 |
| 0.6 |
0.9880 |
3.98 |
0.00590 |
0.001030 |
0.003890 |
0.00792 |
| 0.7 |
0.9870 |
5.01 |
0.00590 |
0.001030 |
0.003880 |
0.00792 |
| 0.8 |
0.9850 |
6.31 |
0.00590 |
0.001030 |
0.003880 |
0.00792 |
| 0.9 |
0.9810 |
7.94 |
0.00590 |
0.001030 |
0.003880 |
0.00793 |
| 1.0 |
0.9810 |
10.00 |
0.00590 |
0.001030 |
0.003880 |
0.00793 |
| 1.1 |
0.9810 |
12.60 |
0.00590 |
0.001030 |
0.003880 |
0.00793 |
| 1.2 |
0.9660 |
15.80 |
0.00590 |
0.001050 |
0.003840 |
0.00796 |
| 1.3 |
0.9660 |
20.00 |
0.00590 |
0.001050 |
0.003840 |
0.00796 |
| 1.4 |
0.9660 |
25.10 |
0.00590 |
0.001050 |
0.003840 |
0.00796 |
| 1.5 |
0.9660 |
31.60 |
0.00590 |
0.001050 |
0.003840 |
0.00796 |
| 1.6 |
0.9500 |
39.80 |
0.00590 |
0.001050 |
0.003840 |
0.00796 |
| 1.7 |
0.9440 |
50.10 |
0.00590 |
0.001060 |
0.003820 |
0.00798 |
| 1.8 |
0.9390 |
63.10 |
0.00568 |
0.001030 |
0.003660 |
0.00771 |
| 1.9 |
0.9290 |
79.40 |
0.00560 |
0.001030 |
0.003580 |
0.00762 |
| 2.0 |
0.8990 |
100.00 |
0.00559 |
0.001040 |
0.003540 |
0.00763 |
| 2.1 |
0.8850 |
126.00 |
0.00521 |
0.001010 |
0.003230 |
0.00719 |
| 2.2 |
0.8550 |
158.00 |
0.00491 |
0.000996 |
0.002950 |
0.00686 |
| 2.3 |
0.8420 |
200.00 |
0.00462 |
0.000968 |
0.002720 |
0.00651 |
| 2.4 |
0.8180 |
251.00 |
0.00423 |
0.000935 |
0.002400 |
0.00606 |
| 2.5 |
0.7640 |
316.00 |
0.00395 |
0.000928 |
0.002130 |
0.00576 |
| 2.6 |
0.7150 |
398.00 |
0.00384 |
0.000948 |
0.001980 |
0.00570 |
| 2.7 |
0.6380 |
501.00 |
0.00377 |
0.000965 |
0.001880 |
0.00566 |
| 2.8 |
0.5210 |
631.00 |
0.00377 |
0.001100 |
0.001620 |
0.00592 |
| 2.9 |
0.4700 |
794.00 |
0.00377 |
0.001200 |
0.001430 |
0.00612 |
| 3.0 |
0.4320 |
1000.00 |
0.00377 |
0.001220 |
0.001380 |
0.00617 |
| 3.1 |
0.3450 |
1260.00 |
0.00377 |
0.001330 |
0.001170 |
0.00637 |
| 3.2 |
0.2870 |
1580.00 |
0.00377 |
0.001490 |
0.000858 |
0.00669 |
| 3.3 |
0.2200 |
2000.00 |
0.00377 |
0.001740 |
0.000354 |
0.00719 |
| 3.4 |
0.1630 |
2510.00 |
0.00377 |
0.002690 |
-0.001510 |
0.00905 |
| 3.5 |
0.1270 |
3160.00 |
0.00377 |
0.004290 |
-0.004640 |
0.01220 |
| 3.6 |
0.0993 |
3980.00 |
0.00377 |
0.004950 |
-0.005920 |
0.01350 |
| 3.7 |
0.0799 |
5010.00 |
0.00377 |
0.004820 |
-0.005670 |
0.01320 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9920 |
0.00584 |
0.001020 |
0.003830 |
0.00784 |
| 0.2 |
1.58 |
0.9920 |
0.00584 |
0.001020 |
0.003830 |
0.00784 |
| 0.3 |
2.00 |
0.9920 |
0.00584 |
0.001020 |
0.003830 |
0.00784 |
| 0.4 |
2.51 |
0.9900 |
0.00585 |
0.001030 |
0.003840 |
0.00786 |
| 0.5 |
3.16 |
0.9880 |
0.00586 |
0.001030 |
0.003840 |
0.00787 |
| 0.6 |
3.98 |
0.9880 |
0.00586 |
0.001030 |
0.003840 |
0.00787 |
| 0.7 |
5.01 |
0.9870 |
0.00586 |
0.001030 |
0.003850 |
0.00788 |
| 0.8 |
6.31 |
0.9850 |
0.00587 |
0.001030 |
0.003850 |
0.00790 |
| 0.9 |
7.94 |
0.9810 |
0.00590 |
0.001030 |
0.003870 |
0.00792 |
| 1.0 |
10.00 |
0.9810 |
0.00590 |
0.001030 |
0.003870 |
0.00792 |
| 1.1 |
12.60 |
0.9810 |
0.00590 |
0.001030 |
0.003870 |
0.00792 |
| 1.2 |
15.80 |
0.9660 |
0.00599 |
0.001050 |
0.003930 |
0.00805 |
| 1.3 |
20.00 |
0.9660 |
0.00599 |
0.001050 |
0.003930 |
0.00805 |
| 1.4 |
25.10 |
0.9660 |
0.00599 |
0.001050 |
0.003930 |
0.00805 |
| 1.5 |
31.60 |
0.9660 |
0.00599 |
0.001050 |
0.003930 |
0.00805 |
| 1.6 |
39.80 |
0.9500 |
0.00592 |
0.001050 |
0.003860 |
0.00798 |
| 1.7 |
50.10 |
0.9440 |
0.00597 |
0.001060 |
0.003890 |
0.00804 |
| 1.8 |
63.10 |
0.9390 |
0.00568 |
0.001030 |
0.003660 |
0.00771 |
| 1.9 |
79.40 |
0.9290 |
0.00560 |
0.001030 |
0.003580 |
0.00762 |
| 2.0 |
100.00 |
0.8990 |
0.00559 |
0.001040 |
0.003540 |
0.00763 |
| 2.1 |
126.00 |
0.8850 |
0.00521 |
0.001010 |
0.003230 |
0.00719 |
| 2.2 |
158.00 |
0.8550 |
0.00491 |
0.000996 |
0.002950 |
0.00686 |
| 2.3 |
200.00 |
0.8420 |
0.00462 |
0.000968 |
0.002720 |
0.00651 |
| 2.4 |
251.00 |
0.8180 |
0.00423 |
0.000935 |
0.002400 |
0.00606 |
| 2.5 |
316.00 |
0.7640 |
0.00395 |
0.000928 |
0.002130 |
0.00576 |
| 2.6 |
398.00 |
0.7150 |
0.00384 |
0.000948 |
0.001980 |
0.00570 |
| 2.7 |
501.00 |
0.6380 |
0.00359 |
0.000965 |
0.001690 |
0.00548 |
| 2.8 |
631.00 |
0.5210 |
0.00375 |
0.001100 |
0.001600 |
0.00590 |
| 2.9 |
794.00 |
0.4700 |
0.00394 |
0.001200 |
0.001590 |
0.00628 |
| 3.0 |
1000.00 |
0.4320 |
0.00383 |
0.001220 |
0.001440 |
0.00623 |
| 3.1 |
1260.00 |
0.3450 |
0.00360 |
0.001330 |
0.000997 |
0.00620 |
| 3.2 |
1580.00 |
0.2870 |
0.00381 |
0.001490 |
0.000896 |
0.00673 |
| 3.3 |
2000.00 |
0.2200 |
0.00394 |
0.001740 |
0.000523 |
0.00736 |
| 3.4 |
2510.00 |
0.1630 |
0.00597 |
0.002690 |
0.000691 |
0.01130 |
| 3.5 |
3160.00 |
0.1270 |
0.00909 |
0.004290 |
0.000679 |
0.01750 |
| 3.6 |
3980.00 |
0.0993 |
0.00928 |
0.004950 |
-0.000413 |
0.01900 |
| 3.7 |
5010.00 |
0.0799 |
0.00699 |
0.004820 |
-0.002460 |
0.01640 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.228 |
0.164 |
-0.09420 |
0.549 |
| 0.1 |
0.9920 |
1.26 |
0.234 |
0.173 |
-0.10500 |
0.573 |
| 0.2 |
0.9920 |
1.58 |
0.234 |
0.173 |
-0.10500 |
0.573 |
| 0.3 |
0.9920 |
2.00 |
0.234 |
0.173 |
-0.10500 |
0.573 |
| 0.4 |
0.9900 |
2.51 |
0.234 |
0.173 |
-0.10600 |
0.573 |
| 0.5 |
0.9880 |
3.16 |
0.234 |
0.173 |
-0.10600 |
0.573 |
| 0.6 |
0.9880 |
3.98 |
0.234 |
0.173 |
-0.10600 |
0.573 |
| 0.7 |
0.9870 |
5.01 |
0.234 |
0.173 |
-0.10600 |
0.574 |
| 0.8 |
0.9850 |
6.31 |
0.234 |
0.174 |
-0.10700 |
0.574 |
| 0.9 |
0.9810 |
7.94 |
0.234 |
0.174 |
-0.10700 |
0.574 |
| 1.0 |
0.9810 |
10.00 |
0.234 |
0.174 |
-0.10700 |
0.574 |
| 1.1 |
0.9810 |
12.60 |
0.234 |
0.174 |
-0.10700 |
0.574 |
| 1.2 |
0.9660 |
15.80 |
0.234 |
0.176 |
-0.11000 |
0.578 |
| 1.3 |
0.9660 |
20.00 |
0.234 |
0.176 |
-0.11000 |
0.578 |
| 1.4 |
0.9660 |
25.10 |
0.234 |
0.176 |
-0.11000 |
0.578 |
| 1.5 |
0.9660 |
31.60 |
0.234 |
0.176 |
-0.11000 |
0.578 |
| 1.6 |
0.9500 |
39.80 |
0.234 |
0.176 |
-0.11100 |
0.578 |
| 1.7 |
0.9440 |
50.10 |
0.234 |
0.177 |
-0.11200 |
0.580 |
| 1.8 |
0.9390 |
63.10 |
0.262 |
0.171 |
-0.07360 |
0.597 |
| 1.9 |
0.9290 |
79.40 |
0.273 |
0.170 |
-0.06020 |
0.606 |
| 2.0 |
0.8990 |
100.00 |
0.274 |
0.171 |
-0.06110 |
0.610 |
| 2.1 |
0.8850 |
126.00 |
0.324 |
0.164 |
0.00301 |
0.644 |
| 2.2 |
0.8550 |
158.00 |
0.363 |
0.159 |
0.05190 |
0.674 |
| 2.3 |
0.8420 |
200.00 |
0.401 |
0.153 |
0.10200 |
0.700 |
| 2.4 |
0.8180 |
251.00 |
0.451 |
0.145 |
0.16700 |
0.735 |
| 2.5 |
0.7640 |
316.00 |
0.488 |
0.141 |
0.21100 |
0.765 |
| 2.6 |
0.7150 |
398.00 |
0.502 |
0.143 |
0.22200 |
0.781 |
| 2.7 |
0.6380 |
501.00 |
0.510 |
0.144 |
0.22800 |
0.792 |
| 2.8 |
0.5210 |
631.00 |
0.510 |
0.159 |
0.19800 |
0.822 |
| 2.9 |
0.4700 |
794.00 |
0.510 |
0.171 |
0.17600 |
0.845 |
| 3.0 |
0.4320 |
1000.00 |
0.510 |
0.174 |
0.17000 |
0.850 |
| 3.1 |
0.3450 |
1260.00 |
0.510 |
0.186 |
0.14500 |
0.875 |
| 3.2 |
0.2870 |
1580.00 |
0.510 |
0.206 |
0.10700 |
0.913 |
| 3.3 |
0.2200 |
2000.00 |
0.510 |
0.237 |
0.04520 |
0.975 |
| 3.4 |
0.1630 |
2510.00 |
0.510 |
0.357 |
-0.19000 |
1.210 |
| 3.5 |
0.1270 |
3160.00 |
0.510 |
0.562 |
-0.59100 |
1.610 |
| 3.6 |
0.0993 |
3980.00 |
0.510 |
0.646 |
-0.75600 |
1.780 |
| 3.7 |
0.0799 |
5010.00 |
0.510 |
0.629 |
-0.72400 |
1.740 |
IgG_gp70V1V2AP
Monotone

| 0.0 |
1.000 |
1.00 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| 0.1 |
0.998 |
1.26 |
0.00583 |
0.001020 |
0.003840 |
0.00783 |
| 0.2 |
0.998 |
1.58 |
0.00583 |
0.001020 |
0.003840 |
0.00783 |
| 0.3 |
0.998 |
2.00 |
0.00583 |
0.001020 |
0.003840 |
0.00783 |
| 0.4 |
0.997 |
2.51 |
0.00583 |
0.001020 |
0.003830 |
0.00783 |
| 0.5 |
0.997 |
3.16 |
0.00583 |
0.001020 |
0.003830 |
0.00783 |
| 0.6 |
0.992 |
3.98 |
0.00583 |
0.001020 |
0.003830 |
0.00784 |
| 0.7 |
0.986 |
5.01 |
0.00583 |
0.001030 |
0.003820 |
0.00785 |
| 0.8 |
0.982 |
6.31 |
0.00583 |
0.001030 |
0.003810 |
0.00786 |
| 0.9 |
0.972 |
7.94 |
0.00583 |
0.001030 |
0.003820 |
0.00785 |
| 1.0 |
0.972 |
10.00 |
0.00583 |
0.001030 |
0.003820 |
0.00785 |
| 1.1 |
0.972 |
12.60 |
0.00583 |
0.001030 |
0.003820 |
0.00785 |
| 1.2 |
0.972 |
15.80 |
0.00583 |
0.001030 |
0.003820 |
0.00785 |
| 1.3 |
0.954 |
20.00 |
0.00583 |
0.001050 |
0.003780 |
0.00789 |
| 1.4 |
0.946 |
25.10 |
0.00583 |
0.001060 |
0.003760 |
0.00791 |
| 1.5 |
0.945 |
31.60 |
0.00583 |
0.001040 |
0.003790 |
0.00788 |
| 1.6 |
0.935 |
39.80 |
0.00583 |
0.001050 |
0.003770 |
0.00789 |
| 1.7 |
0.917 |
50.10 |
0.00553 |
0.001020 |
0.003520 |
0.00754 |
| 1.8 |
0.905 |
63.10 |
0.00553 |
0.001040 |
0.003490 |
0.00756 |
| 1.9 |
0.886 |
79.40 |
0.00515 |
0.000990 |
0.003210 |
0.00709 |
| 2.0 |
0.842 |
100.00 |
0.00515 |
0.001040 |
0.003110 |
0.00719 |
| 2.1 |
0.787 |
126.00 |
0.00514 |
0.001070 |
0.003050 |
0.00724 |
| 2.2 |
0.725 |
158.00 |
0.00511 |
0.001100 |
0.002950 |
0.00727 |
| 2.3 |
0.659 |
200.00 |
0.00491 |
0.001050 |
0.002860 |
0.00696 |
| 2.4 |
0.609 |
251.00 |
0.00491 |
0.001110 |
0.002740 |
0.00707 |
| 2.5 |
0.521 |
316.00 |
0.00491 |
0.001280 |
0.002400 |
0.00742 |
| 2.6 |
0.456 |
398.00 |
0.00491 |
0.001410 |
0.002140 |
0.00767 |
| 2.7 |
0.395 |
501.00 |
0.00491 |
0.001600 |
0.001780 |
0.00804 |
| 2.8 |
0.335 |
631.00 |
0.00491 |
0.001640 |
0.001690 |
0.00812 |
| 2.9 |
0.256 |
794.00 |
0.00491 |
0.001780 |
0.001420 |
0.00840 |
| 3.0 |
0.201 |
1000.00 |
0.00491 |
0.002390 |
0.000221 |
0.00959 |
| 3.1 |
0.170 |
1260.00 |
0.00491 |
0.002340 |
0.000324 |
0.00949 |
| 3.2 |
0.120 |
1580.00 |
0.00491 |
0.003520 |
-0.001990 |
0.01180 |
| 3.3 |
0.091 |
2000.00 |
0.00491 |
0.004630 |
-0.004170 |
0.01400 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.998 |
0.00581 |
0.001020 |
0.003810 |
0.00780 |
| 0.2 |
1.58 |
0.998 |
0.00581 |
0.001020 |
0.003810 |
0.00780 |
| 0.3 |
2.00 |
0.998 |
0.00581 |
0.001020 |
0.003810 |
0.00780 |
| 0.4 |
2.51 |
0.997 |
0.00581 |
0.001020 |
0.003810 |
0.00781 |
| 0.5 |
3.16 |
0.997 |
0.00581 |
0.001020 |
0.003810 |
0.00781 |
| 0.6 |
3.98 |
0.992 |
0.00583 |
0.001020 |
0.003830 |
0.00784 |
| 0.7 |
5.01 |
0.986 |
0.00587 |
0.001030 |
0.003850 |
0.00788 |
| 0.8 |
6.31 |
0.982 |
0.00589 |
0.001030 |
0.003870 |
0.00792 |
| 0.9 |
7.94 |
0.972 |
0.00579 |
0.001030 |
0.003780 |
0.00780 |
| 1.0 |
10.00 |
0.972 |
0.00579 |
0.001030 |
0.003780 |
0.00780 |
| 1.1 |
12.60 |
0.972 |
0.00579 |
0.001030 |
0.003780 |
0.00780 |
| 1.2 |
15.80 |
0.972 |
0.00579 |
0.001030 |
0.003780 |
0.00780 |
| 1.3 |
20.00 |
0.954 |
0.00591 |
0.001050 |
0.003860 |
0.00797 |
| 1.4 |
25.10 |
0.946 |
0.00596 |
0.001060 |
0.003890 |
0.00804 |
| 1.5 |
31.60 |
0.945 |
0.00581 |
0.001040 |
0.003770 |
0.00785 |
| 1.6 |
39.80 |
0.935 |
0.00586 |
0.001050 |
0.003790 |
0.00792 |
| 1.7 |
50.10 |
0.917 |
0.00549 |
0.001020 |
0.003490 |
0.00750 |
| 1.8 |
63.10 |
0.905 |
0.00556 |
0.001040 |
0.003530 |
0.00760 |
| 1.9 |
79.40 |
0.886 |
0.00503 |
0.000990 |
0.003090 |
0.00697 |
| 2.0 |
100.00 |
0.842 |
0.00527 |
0.001040 |
0.003230 |
0.00730 |
| 2.1 |
126.00 |
0.787 |
0.00514 |
0.001070 |
0.003050 |
0.00724 |
| 2.2 |
158.00 |
0.725 |
0.00511 |
0.001100 |
0.002950 |
0.00727 |
| 2.3 |
200.00 |
0.659 |
0.00431 |
0.001050 |
0.002260 |
0.00636 |
| 2.4 |
251.00 |
0.609 |
0.00443 |
0.001110 |
0.002260 |
0.00660 |
| 2.5 |
316.00 |
0.521 |
0.00494 |
0.001280 |
0.002430 |
0.00745 |
| 2.6 |
398.00 |
0.456 |
0.00513 |
0.001410 |
0.002360 |
0.00789 |
| 2.7 |
501.00 |
0.395 |
0.00558 |
0.001600 |
0.002450 |
0.00870 |
| 2.8 |
631.00 |
0.335 |
0.00534 |
0.001640 |
0.002120 |
0.00855 |
| 2.9 |
794.00 |
0.256 |
0.00457 |
0.001780 |
0.001080 |
0.00806 |
| 3.0 |
1000.00 |
0.201 |
0.00596 |
0.002390 |
0.001280 |
0.01060 |
| 3.1 |
1260.00 |
0.170 |
0.00521 |
0.002340 |
0.000621 |
0.00979 |
| 3.2 |
1580.00 |
0.120 |
0.00703 |
0.003520 |
0.000132 |
0.01390 |
| 3.3 |
2000.00 |
0.091 |
0.00707 |
0.004630 |
-0.002010 |
0.01610 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.228 |
0.164 |
-0.09420 |
0.549 |
| 0.1 |
0.998 |
1.26 |
0.242 |
0.172 |
-0.09380 |
0.579 |
| 0.2 |
0.998 |
1.58 |
0.242 |
0.172 |
-0.09380 |
0.579 |
| 0.3 |
0.998 |
2.00 |
0.242 |
0.172 |
-0.09380 |
0.579 |
| 0.4 |
0.997 |
2.51 |
0.242 |
0.172 |
-0.09410 |
0.579 |
| 0.5 |
0.997 |
3.16 |
0.242 |
0.172 |
-0.09410 |
0.579 |
| 0.6 |
0.992 |
3.98 |
0.242 |
0.172 |
-0.09490 |
0.580 |
| 0.7 |
0.986 |
5.01 |
0.242 |
0.173 |
-0.09570 |
0.581 |
| 0.8 |
0.982 |
6.31 |
0.242 |
0.173 |
-0.09660 |
0.582 |
| 0.9 |
0.972 |
7.94 |
0.242 |
0.172 |
-0.09550 |
0.580 |
| 1.0 |
0.972 |
10.00 |
0.242 |
0.172 |
-0.09550 |
0.580 |
| 1.1 |
0.972 |
12.60 |
0.242 |
0.172 |
-0.09550 |
0.580 |
| 1.2 |
0.972 |
15.80 |
0.242 |
0.172 |
-0.09550 |
0.580 |
| 1.3 |
0.954 |
20.00 |
0.242 |
0.175 |
-0.09960 |
0.585 |
| 1.4 |
0.946 |
25.10 |
0.242 |
0.176 |
-0.10200 |
0.587 |
| 1.5 |
0.945 |
31.60 |
0.243 |
0.174 |
-0.09820 |
0.583 |
| 1.6 |
0.935 |
39.80 |
0.243 |
0.175 |
-0.10000 |
0.585 |
| 1.7 |
0.917 |
50.10 |
0.282 |
0.169 |
-0.04820 |
0.612 |
| 1.8 |
0.905 |
63.10 |
0.282 |
0.170 |
-0.05100 |
0.615 |
| 1.9 |
0.886 |
79.40 |
0.332 |
0.161 |
0.01670 |
0.647 |
| 2.0 |
0.842 |
100.00 |
0.332 |
0.166 |
0.00639 |
0.657 |
| 2.1 |
0.787 |
126.00 |
0.332 |
0.169 |
0.00131 |
0.663 |
| 2.2 |
0.725 |
158.00 |
0.336 |
0.172 |
-0.00141 |
0.673 |
| 2.3 |
0.659 |
200.00 |
0.363 |
0.164 |
0.04120 |
0.684 |
| 2.4 |
0.609 |
251.00 |
0.363 |
0.170 |
0.02860 |
0.697 |
| 2.5 |
0.521 |
316.00 |
0.363 |
0.190 |
-0.00970 |
0.735 |
| 2.6 |
0.456 |
398.00 |
0.363 |
0.205 |
-0.03900 |
0.764 |
| 2.7 |
0.395 |
501.00 |
0.363 |
0.227 |
-0.08170 |
0.807 |
| 2.8 |
0.335 |
631.00 |
0.363 |
0.232 |
-0.09180 |
0.817 |
| 2.9 |
0.256 |
794.00 |
0.363 |
0.249 |
-0.12500 |
0.850 |
| 3.0 |
0.201 |
1000.00 |
0.363 |
0.324 |
-0.27200 |
0.997 |
| 3.1 |
0.170 |
1260.00 |
0.363 |
0.317 |
-0.25900 |
0.985 |
| 3.2 |
0.120 |
1580.00 |
0.363 |
0.466 |
-0.55100 |
1.280 |
| 3.3 |
0.091 |
2000.00 |
0.363 |
0.608 |
-0.83000 |
1.560 |
IgG_gp70V1V2C
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| 0.1 |
0.9880 |
1.26 |
0.00592 |
0.001030 |
0.003900 |
0.00794 |
| 0.2 |
0.9880 |
1.58 |
0.00592 |
0.001030 |
0.003900 |
0.00794 |
| 0.3 |
0.9880 |
2.00 |
0.00592 |
0.001030 |
0.003900 |
0.00794 |
| 0.4 |
0.9860 |
2.51 |
0.00592 |
0.001030 |
0.003890 |
0.00795 |
| 0.5 |
0.9840 |
3.16 |
0.00592 |
0.001040 |
0.003890 |
0.00795 |
| 0.6 |
0.9840 |
3.98 |
0.00592 |
0.001040 |
0.003890 |
0.00795 |
| 0.7 |
0.9820 |
5.01 |
0.00592 |
0.001040 |
0.003890 |
0.00795 |
| 0.8 |
0.9820 |
6.31 |
0.00592 |
0.001040 |
0.003890 |
0.00795 |
| 0.9 |
0.9760 |
7.94 |
0.00592 |
0.001040 |
0.003880 |
0.00796 |
| 1.0 |
0.9660 |
10.00 |
0.00592 |
0.001050 |
0.003860 |
0.00798 |
| 1.1 |
0.9590 |
12.60 |
0.00592 |
0.001060 |
0.003840 |
0.00800 |
| 1.2 |
0.9530 |
15.80 |
0.00592 |
0.001050 |
0.003860 |
0.00798 |
| 1.3 |
0.9410 |
20.00 |
0.00592 |
0.001070 |
0.003830 |
0.00801 |
| 1.4 |
0.9310 |
25.10 |
0.00574 |
0.001050 |
0.003690 |
0.00779 |
| 1.5 |
0.9220 |
31.60 |
0.00553 |
0.001020 |
0.003520 |
0.00754 |
| 1.6 |
0.9080 |
39.80 |
0.00553 |
0.001040 |
0.003490 |
0.00756 |
| 1.7 |
0.9010 |
50.10 |
0.00510 |
0.000990 |
0.003160 |
0.00704 |
| 1.8 |
0.8820 |
63.10 |
0.00491 |
0.000981 |
0.002990 |
0.00683 |
| 1.9 |
0.8550 |
79.40 |
0.00473 |
0.000970 |
0.002830 |
0.00663 |
| 2.0 |
0.8310 |
100.00 |
0.00473 |
0.000978 |
0.002820 |
0.00665 |
| 2.1 |
0.7940 |
126.00 |
0.00473 |
0.001020 |
0.002730 |
0.00674 |
| 2.2 |
0.7360 |
158.00 |
0.00461 |
0.001020 |
0.002610 |
0.00661 |
| 2.3 |
0.6760 |
200.00 |
0.00461 |
0.001050 |
0.002540 |
0.00667 |
| 2.4 |
0.6180 |
251.00 |
0.00461 |
0.001160 |
0.002330 |
0.00689 |
| 2.5 |
0.5660 |
316.00 |
0.00454 |
0.001160 |
0.002270 |
0.00680 |
| 2.6 |
0.5210 |
398.00 |
0.00454 |
0.001220 |
0.002150 |
0.00693 |
| 2.7 |
0.4440 |
501.00 |
0.00389 |
0.001220 |
0.001500 |
0.00627 |
| 2.8 |
0.3780 |
631.00 |
0.00387 |
0.001340 |
0.001240 |
0.00649 |
| 2.9 |
0.3070 |
794.00 |
0.00387 |
0.001220 |
0.001470 |
0.00627 |
| 3.0 |
0.2510 |
1000.00 |
0.00387 |
0.001420 |
0.001080 |
0.00665 |
| 3.1 |
0.2010 |
1260.00 |
0.00387 |
0.001570 |
0.000784 |
0.00695 |
| 3.2 |
0.1310 |
1580.00 |
0.00387 |
0.002690 |
-0.001410 |
0.00914 |
| 3.3 |
0.0791 |
2000.00 |
0.00387 |
0.003750 |
-0.003490 |
0.01120 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9880 |
0.00588 |
0.001030 |
0.003850 |
0.00790 |
| 0.2 |
1.58 |
0.9880 |
0.00588 |
0.001030 |
0.003850 |
0.00790 |
| 0.3 |
2.00 |
0.9880 |
0.00588 |
0.001030 |
0.003850 |
0.00790 |
| 0.4 |
2.51 |
0.9860 |
0.00588 |
0.001030 |
0.003860 |
0.00791 |
| 0.5 |
3.16 |
0.9840 |
0.00589 |
0.001040 |
0.003860 |
0.00792 |
| 0.6 |
3.98 |
0.9840 |
0.00589 |
0.001040 |
0.003860 |
0.00792 |
| 0.7 |
5.01 |
0.9820 |
0.00591 |
0.001040 |
0.003870 |
0.00794 |
| 0.8 |
6.31 |
0.9820 |
0.00591 |
0.001040 |
0.003870 |
0.00794 |
| 0.9 |
7.94 |
0.9760 |
0.00594 |
0.001040 |
0.003900 |
0.00798 |
| 1.0 |
10.00 |
0.9660 |
0.00599 |
0.001050 |
0.003930 |
0.00805 |
| 1.1 |
12.60 |
0.9590 |
0.00603 |
0.001060 |
0.003950 |
0.00811 |
| 1.2 |
15.80 |
0.9530 |
0.00591 |
0.001050 |
0.003850 |
0.00797 |
| 1.3 |
20.00 |
0.9410 |
0.00599 |
0.001070 |
0.003900 |
0.00808 |
| 1.4 |
25.10 |
0.9310 |
0.00574 |
0.001050 |
0.003690 |
0.00779 |
| 1.5 |
31.60 |
0.9220 |
0.00550 |
0.001020 |
0.003490 |
0.00751 |
| 1.6 |
39.80 |
0.9080 |
0.00556 |
0.001040 |
0.003530 |
0.00760 |
| 1.7 |
50.10 |
0.9010 |
0.00510 |
0.000990 |
0.003160 |
0.00704 |
| 1.8 |
63.10 |
0.8820 |
0.00491 |
0.000981 |
0.002990 |
0.00683 |
| 1.9 |
79.40 |
0.8550 |
0.00470 |
0.000970 |
0.002800 |
0.00660 |
| 2.0 |
100.00 |
0.8310 |
0.00465 |
0.000978 |
0.002740 |
0.00657 |
| 2.1 |
126.00 |
0.7940 |
0.00485 |
0.001020 |
0.002840 |
0.00685 |
| 2.2 |
158.00 |
0.7360 |
0.00457 |
0.001020 |
0.002570 |
0.00656 |
| 2.3 |
200.00 |
0.6760 |
0.00442 |
0.001050 |
0.002350 |
0.00648 |
| 2.4 |
251.00 |
0.6180 |
0.00485 |
0.001160 |
0.002570 |
0.00713 |
| 2.5 |
316.00 |
0.5660 |
0.00449 |
0.001160 |
0.002220 |
0.00676 |
| 2.6 |
398.00 |
0.5210 |
0.00459 |
0.001220 |
0.002200 |
0.00698 |
| 2.7 |
501.00 |
0.4440 |
0.00389 |
0.001220 |
0.001500 |
0.00627 |
| 2.8 |
631.00 |
0.3780 |
0.00386 |
0.001340 |
0.001240 |
0.00649 |
| 2.9 |
794.00 |
0.3070 |
0.00298 |
0.001220 |
0.000584 |
0.00538 |
| 3.0 |
1000.00 |
0.2510 |
0.00320 |
0.001420 |
0.000419 |
0.00599 |
| 3.1 |
1260.00 |
0.2010 |
0.00325 |
0.001570 |
0.000169 |
0.00633 |
| 3.2 |
1580.00 |
0.1310 |
0.00496 |
0.002690 |
-0.000318 |
0.01020 |
| 3.3 |
2000.00 |
0.0791 |
0.00600 |
0.003750 |
-0.001360 |
0.01340 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.228 |
0.164 |
-0.0942 |
0.549 |
| 0.1 |
0.9880 |
1.26 |
0.231 |
0.174 |
-0.1100 |
0.572 |
| 0.2 |
0.9880 |
1.58 |
0.231 |
0.174 |
-0.1100 |
0.572 |
| 0.3 |
0.9880 |
2.00 |
0.231 |
0.174 |
-0.1100 |
0.572 |
| 0.4 |
0.9860 |
2.51 |
0.231 |
0.174 |
-0.1100 |
0.572 |
| 0.5 |
0.9840 |
3.16 |
0.231 |
0.174 |
-0.1100 |
0.573 |
| 0.6 |
0.9840 |
3.98 |
0.231 |
0.174 |
-0.1100 |
0.573 |
| 0.7 |
0.9820 |
5.01 |
0.231 |
0.175 |
-0.1110 |
0.573 |
| 0.8 |
0.9820 |
6.31 |
0.231 |
0.175 |
-0.1110 |
0.573 |
| 0.9 |
0.9760 |
7.94 |
0.231 |
0.175 |
-0.1110 |
0.574 |
| 1.0 |
0.9660 |
10.00 |
0.231 |
0.176 |
-0.1130 |
0.576 |
| 1.1 |
0.9590 |
12.60 |
0.231 |
0.177 |
-0.1150 |
0.577 |
| 1.2 |
0.9530 |
15.80 |
0.231 |
0.176 |
-0.1130 |
0.576 |
| 1.3 |
0.9410 |
20.00 |
0.231 |
0.177 |
-0.1160 |
0.579 |
| 1.4 |
0.9310 |
25.10 |
0.254 |
0.173 |
-0.0852 |
0.594 |
| 1.5 |
0.9220 |
31.60 |
0.282 |
0.169 |
-0.0485 |
0.613 |
| 1.6 |
0.9080 |
39.80 |
0.282 |
0.170 |
-0.0512 |
0.615 |
| 1.7 |
0.9010 |
50.10 |
0.337 |
0.160 |
0.0234 |
0.651 |
| 1.8 |
0.8820 |
63.10 |
0.362 |
0.157 |
0.0543 |
0.670 |
| 1.9 |
0.8550 |
79.40 |
0.385 |
0.154 |
0.0836 |
0.687 |
| 2.0 |
0.8310 |
100.00 |
0.385 |
0.155 |
0.0819 |
0.689 |
| 2.1 |
0.7940 |
126.00 |
0.385 |
0.160 |
0.0726 |
0.698 |
| 2.2 |
0.7360 |
158.00 |
0.402 |
0.158 |
0.0919 |
0.711 |
| 2.3 |
0.6760 |
200.00 |
0.402 |
0.162 |
0.0848 |
0.719 |
| 2.4 |
0.6180 |
251.00 |
0.402 |
0.174 |
0.0608 |
0.743 |
| 2.5 |
0.5660 |
316.00 |
0.411 |
0.172 |
0.0725 |
0.749 |
| 2.6 |
0.5210 |
398.00 |
0.411 |
0.180 |
0.0579 |
0.763 |
| 2.7 |
0.4440 |
501.00 |
0.495 |
0.174 |
0.1540 |
0.836 |
| 2.8 |
0.3780 |
631.00 |
0.498 |
0.189 |
0.1280 |
0.868 |
| 2.9 |
0.3070 |
794.00 |
0.498 |
0.175 |
0.1560 |
0.840 |
| 3.0 |
0.2510 |
1000.00 |
0.498 |
0.198 |
0.1090 |
0.887 |
| 3.1 |
0.2010 |
1260.00 |
0.498 |
0.217 |
0.0735 |
0.923 |
| 3.2 |
0.1310 |
1580.00 |
0.498 |
0.357 |
-0.2020 |
1.200 |
| 3.3 |
0.0791 |
2000.00 |
0.498 |
0.493 |
-0.4680 |
1.460 |
IgG_gp70BCaseA2V1V2169K
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| 0.1 |
0.9980 |
1.26 |
0.00584 |
0.001020 |
0.003840 |
0.00784 |
| 0.2 |
0.9980 |
1.58 |
0.00584 |
0.001020 |
0.003840 |
0.00784 |
| 0.3 |
0.9980 |
2.00 |
0.00584 |
0.001020 |
0.003840 |
0.00784 |
| 0.4 |
0.9970 |
2.51 |
0.00584 |
0.001020 |
0.003840 |
0.00784 |
| 0.5 |
0.9950 |
3.16 |
0.00584 |
0.001020 |
0.003840 |
0.00784 |
| 0.6 |
0.9950 |
3.98 |
0.00584 |
0.001020 |
0.003840 |
0.00784 |
| 0.7 |
0.9940 |
5.01 |
0.00584 |
0.001020 |
0.003830 |
0.00784 |
| 0.8 |
0.9940 |
6.31 |
0.00584 |
0.001020 |
0.003830 |
0.00784 |
| 0.9 |
0.9900 |
7.94 |
0.00584 |
0.001030 |
0.003830 |
0.00785 |
| 1.0 |
0.9890 |
10.00 |
0.00584 |
0.001030 |
0.003820 |
0.00785 |
| 1.1 |
0.9890 |
12.60 |
0.00584 |
0.001030 |
0.003820 |
0.00785 |
| 1.2 |
0.9890 |
15.80 |
0.00584 |
0.001030 |
0.003820 |
0.00785 |
| 1.3 |
0.9810 |
20.00 |
0.00584 |
0.001030 |
0.003810 |
0.00787 |
| 1.4 |
0.9740 |
25.10 |
0.00584 |
0.001040 |
0.003790 |
0.00788 |
| 1.5 |
0.9690 |
31.60 |
0.00582 |
0.001030 |
0.003800 |
0.00784 |
| 1.6 |
0.9650 |
39.80 |
0.00582 |
0.001040 |
0.003790 |
0.00784 |
| 1.7 |
0.9630 |
50.10 |
0.00569 |
0.001020 |
0.003690 |
0.00769 |
| 1.8 |
0.9580 |
63.10 |
0.00557 |
0.001010 |
0.003590 |
0.00755 |
| 1.9 |
0.9420 |
79.40 |
0.00536 |
0.000997 |
0.003410 |
0.00732 |
| 2.0 |
0.9420 |
100.00 |
0.00521 |
0.000981 |
0.003290 |
0.00713 |
| 2.1 |
0.9370 |
126.00 |
0.00510 |
0.000972 |
0.003190 |
0.00700 |
| 2.2 |
0.9190 |
158.00 |
0.00505 |
0.000979 |
0.003130 |
0.00697 |
| 2.3 |
0.8900 |
200.00 |
0.00470 |
0.000952 |
0.002830 |
0.00656 |
| 2.4 |
0.8720 |
251.00 |
0.00460 |
0.000948 |
0.002750 |
0.00646 |
| 2.5 |
0.8320 |
316.00 |
0.00449 |
0.000949 |
0.002630 |
0.00635 |
| 2.6 |
0.7830 |
398.00 |
0.00449 |
0.000985 |
0.002560 |
0.00642 |
| 2.7 |
0.7210 |
501.00 |
0.00449 |
0.001030 |
0.002480 |
0.00650 |
| 2.8 |
0.6690 |
631.00 |
0.00444 |
0.001060 |
0.002370 |
0.00652 |
| 2.9 |
0.6140 |
794.00 |
0.00438 |
0.001100 |
0.002230 |
0.00653 |
| 3.0 |
0.5430 |
1000.00 |
0.00433 |
0.001150 |
0.002070 |
0.00659 |
| 3.1 |
0.5020 |
1260.00 |
0.00433 |
0.001260 |
0.001850 |
0.00681 |
| 3.2 |
0.4000 |
1580.00 |
0.00432 |
0.001380 |
0.001600 |
0.00703 |
| 3.3 |
0.3380 |
2000.00 |
0.00425 |
0.001520 |
0.001280 |
0.00722 |
| 3.4 |
0.2650 |
2510.00 |
0.00425 |
0.001650 |
0.001030 |
0.00748 |
| 3.5 |
0.2050 |
3160.00 |
0.00425 |
0.002260 |
-0.000171 |
0.00868 |
| 3.6 |
0.1490 |
3980.00 |
0.00384 |
0.001680 |
0.000547 |
0.00714 |
| 3.7 |
0.1310 |
5010.00 |
0.00384 |
0.002150 |
-0.000370 |
0.00805 |
| 3.8 |
0.0971 |
6310.00 |
0.00384 |
0.002740 |
-0.001530 |
0.00921 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9980 |
0.00581 |
0.001020 |
0.003810 |
0.00780 |
| 0.2 |
1.58 |
0.9980 |
0.00581 |
0.001020 |
0.003810 |
0.00780 |
| 0.3 |
2.00 |
0.9980 |
0.00581 |
0.001020 |
0.003810 |
0.00780 |
| 0.4 |
2.51 |
0.9970 |
0.00581 |
0.001020 |
0.003810 |
0.00781 |
| 0.5 |
3.16 |
0.9950 |
0.00582 |
0.001020 |
0.003820 |
0.00782 |
| 0.6 |
3.98 |
0.9950 |
0.00582 |
0.001020 |
0.003820 |
0.00782 |
| 0.7 |
5.01 |
0.9940 |
0.00583 |
0.001020 |
0.003820 |
0.00783 |
| 0.8 |
6.31 |
0.9940 |
0.00583 |
0.001020 |
0.003820 |
0.00783 |
| 0.9 |
7.94 |
0.9900 |
0.00584 |
0.001030 |
0.003830 |
0.00785 |
| 1.0 |
10.00 |
0.9890 |
0.00585 |
0.001030 |
0.003840 |
0.00787 |
| 1.1 |
12.60 |
0.9890 |
0.00585 |
0.001030 |
0.003840 |
0.00787 |
| 1.2 |
15.80 |
0.9890 |
0.00585 |
0.001030 |
0.003840 |
0.00787 |
| 1.3 |
20.00 |
0.9810 |
0.00589 |
0.001030 |
0.003860 |
0.00791 |
| 1.4 |
25.10 |
0.9740 |
0.00592 |
0.001040 |
0.003880 |
0.00797 |
| 1.5 |
31.60 |
0.9690 |
0.00580 |
0.001030 |
0.003780 |
0.00782 |
| 1.6 |
39.80 |
0.9650 |
0.00583 |
0.001040 |
0.003800 |
0.00786 |
| 1.7 |
50.10 |
0.9630 |
0.00569 |
0.001020 |
0.003690 |
0.00769 |
| 1.8 |
63.10 |
0.9580 |
0.00557 |
0.001010 |
0.003590 |
0.00755 |
| 1.9 |
79.40 |
0.9420 |
0.00536 |
0.000997 |
0.003410 |
0.00732 |
| 2.0 |
100.00 |
0.9420 |
0.00521 |
0.000981 |
0.003290 |
0.00713 |
| 2.1 |
126.00 |
0.9370 |
0.00510 |
0.000972 |
0.003190 |
0.00700 |
| 2.2 |
158.00 |
0.9190 |
0.00505 |
0.000979 |
0.003130 |
0.00697 |
| 2.3 |
200.00 |
0.8900 |
0.00470 |
0.000952 |
0.002830 |
0.00656 |
| 2.4 |
251.00 |
0.8720 |
0.00460 |
0.000948 |
0.002750 |
0.00646 |
| 2.5 |
316.00 |
0.8320 |
0.00445 |
0.000949 |
0.002590 |
0.00631 |
| 2.6 |
398.00 |
0.7830 |
0.00451 |
0.000985 |
0.002580 |
0.00644 |
| 2.7 |
501.00 |
0.7210 |
0.00452 |
0.001030 |
0.002500 |
0.00653 |
| 2.8 |
631.00 |
0.6690 |
0.00444 |
0.001060 |
0.002370 |
0.00652 |
| 2.9 |
794.00 |
0.6140 |
0.00438 |
0.001100 |
0.002230 |
0.00653 |
| 3.0 |
1000.00 |
0.5430 |
0.00422 |
0.001150 |
0.001960 |
0.00648 |
| 3.1 |
1260.00 |
0.5020 |
0.00445 |
0.001260 |
0.001970 |
0.00693 |
| 3.2 |
1580.00 |
0.4000 |
0.00432 |
0.001380 |
0.001600 |
0.00703 |
| 3.3 |
2000.00 |
0.3380 |
0.00425 |
0.001520 |
0.001280 |
0.00722 |
| 3.4 |
2510.00 |
0.2650 |
0.00418 |
0.001650 |
0.000954 |
0.00740 |
| 3.5 |
3160.00 |
0.2050 |
0.00515 |
0.002260 |
0.000727 |
0.00958 |
| 3.6 |
3980.00 |
0.1490 |
0.00314 |
0.001680 |
-0.000156 |
0.00643 |
| 3.7 |
5010.00 |
0.1310 |
0.00397 |
0.002150 |
-0.000243 |
0.00818 |
| 3.8 |
6310.00 |
0.0971 |
0.00442 |
0.002740 |
-0.000948 |
0.00979 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.228 |
0.164 |
-0.09420 |
0.549 |
| 0.1 |
0.9980 |
1.26 |
0.242 |
0.172 |
-0.09450 |
0.578 |
| 0.2 |
0.9980 |
1.58 |
0.242 |
0.172 |
-0.09450 |
0.578 |
| 0.3 |
0.9980 |
2.00 |
0.242 |
0.172 |
-0.09450 |
0.578 |
| 0.4 |
0.9970 |
2.51 |
0.242 |
0.172 |
-0.09470 |
0.579 |
| 0.5 |
0.9950 |
3.16 |
0.242 |
0.172 |
-0.09500 |
0.579 |
| 0.6 |
0.9950 |
3.98 |
0.242 |
0.172 |
-0.09500 |
0.579 |
| 0.7 |
0.9940 |
5.01 |
0.242 |
0.172 |
-0.09530 |
0.579 |
| 0.8 |
0.9940 |
6.31 |
0.242 |
0.172 |
-0.09530 |
0.579 |
| 0.9 |
0.9900 |
7.94 |
0.242 |
0.172 |
-0.09590 |
0.580 |
| 1.0 |
0.9890 |
10.00 |
0.242 |
0.172 |
-0.09620 |
0.580 |
| 1.1 |
0.9890 |
12.60 |
0.242 |
0.172 |
-0.09620 |
0.580 |
| 1.2 |
0.9890 |
15.80 |
0.242 |
0.172 |
-0.09620 |
0.580 |
| 1.3 |
0.9810 |
20.00 |
0.242 |
0.173 |
-0.09760 |
0.581 |
| 1.4 |
0.9740 |
25.10 |
0.242 |
0.174 |
-0.09910 |
0.583 |
| 1.5 |
0.9690 |
31.60 |
0.245 |
0.173 |
-0.09330 |
0.583 |
| 1.6 |
0.9650 |
39.80 |
0.245 |
0.173 |
-0.09430 |
0.584 |
| 1.7 |
0.9630 |
50.10 |
0.261 |
0.170 |
-0.07260 |
0.594 |
| 1.8 |
0.9580 |
63.10 |
0.277 |
0.168 |
-0.05130 |
0.605 |
| 1.9 |
0.9420 |
79.40 |
0.304 |
0.164 |
-0.01770 |
0.625 |
| 2.0 |
0.9420 |
100.00 |
0.323 |
0.160 |
0.00888 |
0.638 |
| 2.1 |
0.9370 |
126.00 |
0.338 |
0.158 |
0.02790 |
0.648 |
| 2.2 |
0.9190 |
158.00 |
0.344 |
0.158 |
0.03360 |
0.655 |
| 2.3 |
0.8900 |
200.00 |
0.390 |
0.152 |
0.09260 |
0.687 |
| 2.4 |
0.8720 |
251.00 |
0.402 |
0.150 |
0.10800 |
0.697 |
| 2.5 |
0.8320 |
316.00 |
0.417 |
0.149 |
0.12500 |
0.709 |
| 2.6 |
0.7830 |
398.00 |
0.417 |
0.153 |
0.11700 |
0.717 |
| 2.7 |
0.7210 |
501.00 |
0.417 |
0.158 |
0.10800 |
0.726 |
| 2.8 |
0.6690 |
631.00 |
0.423 |
0.161 |
0.10800 |
0.738 |
| 2.9 |
0.6140 |
794.00 |
0.431 |
0.164 |
0.11000 |
0.753 |
| 3.0 |
0.5430 |
1000.00 |
0.437 |
0.170 |
0.10400 |
0.771 |
| 3.1 |
0.5020 |
1260.00 |
0.437 |
0.183 |
0.07850 |
0.796 |
| 3.2 |
0.4000 |
1580.00 |
0.439 |
0.197 |
0.05310 |
0.826 |
| 3.3 |
0.3380 |
2000.00 |
0.447 |
0.212 |
0.03140 |
0.864 |
| 3.4 |
0.2650 |
2510.00 |
0.447 |
0.228 |
0.00059 |
0.894 |
| 3.5 |
0.2050 |
3160.00 |
0.447 |
0.304 |
-0.14800 |
1.040 |
| 3.6 |
0.1490 |
3980.00 |
0.501 |
0.230 |
0.05070 |
0.952 |
| 3.7 |
0.1310 |
5010.00 |
0.501 |
0.288 |
-0.06360 |
1.070 |
| 3.8 |
0.0971 |
6310.00 |
0.501 |
0.363 |
-0.21000 |
1.210 |
IgG_gp70BCaseA2V1V2mut3
Monotone

| 0.0 |
1.000 |
1.00 |
0.00597 |
0.000929 |
0.00415 |
0.00779 |
| 0.1 |
0.997 |
1.26 |
0.00597 |
0.001030 |
0.00394 |
0.00799 |
| 0.2 |
0.997 |
1.58 |
0.00597 |
0.001030 |
0.00394 |
0.00799 |
| 0.3 |
0.997 |
2.00 |
0.00597 |
0.001030 |
0.00394 |
0.00799 |
| 0.4 |
0.997 |
2.51 |
0.00597 |
0.001030 |
0.00394 |
0.00799 |
| 0.5 |
0.997 |
3.16 |
0.00597 |
0.001030 |
0.00394 |
0.00799 |
| 0.6 |
0.995 |
3.98 |
0.00597 |
0.001040 |
0.00394 |
0.00800 |
| 0.7 |
0.994 |
5.01 |
0.00597 |
0.001040 |
0.00393 |
0.00800 |
| 0.8 |
0.994 |
6.31 |
0.00597 |
0.001040 |
0.00393 |
0.00800 |
| 0.9 |
0.992 |
7.94 |
0.00597 |
0.001040 |
0.00393 |
0.00800 |
| 1.0 |
0.992 |
10.00 |
0.00597 |
0.001040 |
0.00393 |
0.00800 |
| 1.1 |
0.992 |
12.60 |
0.00597 |
0.001040 |
0.00393 |
0.00800 |
| 1.2 |
0.992 |
15.80 |
0.00597 |
0.001040 |
0.00393 |
0.00800 |
| 1.3 |
0.992 |
20.00 |
0.00584 |
0.001020 |
0.00383 |
0.00785 |
| 1.4 |
0.992 |
25.10 |
0.00584 |
0.001020 |
0.00383 |
0.00785 |
| 1.5 |
0.992 |
31.60 |
0.00584 |
0.001020 |
0.00383 |
0.00785 |
| 1.6 |
0.990 |
39.80 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.7 |
0.990 |
50.10 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.8 |
0.990 |
63.10 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.9 |
0.990 |
79.40 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.0 |
0.990 |
100.00 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.1 |
0.990 |
126.00 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.2 |
0.990 |
158.00 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.3 |
0.989 |
200.00 |
0.00584 |
0.001030 |
0.00382 |
0.00786 |
| 2.4 |
0.987 |
251.00 |
0.00573 |
0.001020 |
0.00374 |
0.00772 |
| 2.5 |
0.987 |
316.00 |
0.00573 |
0.001020 |
0.00374 |
0.00772 |
| 2.6 |
0.987 |
398.00 |
0.00573 |
0.001020 |
0.00374 |
0.00772 |
| 2.7 |
0.987 |
501.00 |
0.00573 |
0.001020 |
0.00374 |
0.00772 |
| 2.8 |
0.981 |
631.00 |
0.00573 |
0.001020 |
0.00373 |
0.00773 |
| 2.9 |
0.981 |
794.00 |
0.00573 |
0.001020 |
0.00373 |
0.00773 |
| 3.0 |
0.981 |
1000.00 |
0.00562 |
0.001010 |
0.00365 |
0.00759 |
| 3.1 |
0.976 |
1260.00 |
0.00562 |
0.001010 |
0.00364 |
0.00760 |
| 3.2 |
0.976 |
1580.00 |
0.00549 |
0.000996 |
0.00354 |
0.00744 |
| 3.3 |
0.967 |
2000.00 |
0.00541 |
0.000990 |
0.00347 |
0.00735 |
| 3.4 |
0.963 |
2510.00 |
0.00541 |
0.000994 |
0.00346 |
0.00736 |
| 3.5 |
0.963 |
3160.00 |
0.00527 |
0.000978 |
0.00335 |
0.00719 |
| 3.6 |
0.956 |
3980.00 |
0.00519 |
0.000968 |
0.00329 |
0.00708 |
| 3.7 |
0.940 |
5010.00 |
0.00519 |
0.000939 |
0.00335 |
0.00702 |
| 3.8 |
0.922 |
6310.00 |
0.00519 |
0.000956 |
0.00331 |
0.00706 |
| 3.9 |
0.912 |
7940.00 |
0.00519 |
0.000969 |
0.00329 |
0.00708 |
| 4.0 |
0.830 |
10000.00 |
0.00519 |
0.001030 |
0.00316 |
0.00721 |
| 4.1 |
0.746 |
12600.00 |
0.00519 |
0.001130 |
0.00296 |
0.00741 |
| 4.2 |
0.673 |
15800.00 |
0.00519 |
0.001190 |
0.00284 |
0.00753 |
| 4.3 |
0.550 |
20000.00 |
0.00519 |
0.001410 |
0.00243 |
0.00794 |
| 4.4 |
0.323 |
25100.00 |
0.00519 |
0.001870 |
0.00152 |
0.00885 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00595 |
0.000929 |
0.00392 |
0.00797 |
| 0.1 |
1.26 |
0.997 |
0.00596 |
0.001030 |
0.00393 |
0.00799 |
| 0.2 |
1.58 |
0.997 |
0.00596 |
0.001030 |
0.00393 |
0.00799 |
| 0.3 |
2.00 |
0.997 |
0.00596 |
0.001030 |
0.00393 |
0.00799 |
| 0.4 |
2.51 |
0.997 |
0.00596 |
0.001030 |
0.00393 |
0.00799 |
| 0.5 |
3.16 |
0.997 |
0.00596 |
0.001030 |
0.00393 |
0.00799 |
| 0.6 |
3.98 |
0.995 |
0.00596 |
0.001040 |
0.00393 |
0.00800 |
| 0.7 |
5.01 |
0.994 |
0.00597 |
0.001040 |
0.00394 |
0.00800 |
| 0.8 |
6.31 |
0.994 |
0.00597 |
0.001040 |
0.00394 |
0.00800 |
| 0.9 |
7.94 |
0.992 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 1.0 |
10.00 |
0.992 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 1.1 |
12.60 |
0.992 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 1.2 |
15.80 |
0.992 |
0.00598 |
0.001040 |
0.00394 |
0.00802 |
| 1.3 |
20.00 |
0.992 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.4 |
25.10 |
0.992 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.5 |
31.60 |
0.992 |
0.00583 |
0.001020 |
0.00383 |
0.00784 |
| 1.6 |
39.80 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.7 |
50.10 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.8 |
63.10 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 1.9 |
79.40 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.0 |
100.00 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.1 |
126.00 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.2 |
158.00 |
0.990 |
0.00584 |
0.001030 |
0.00383 |
0.00785 |
| 2.3 |
200.00 |
0.989 |
0.00586 |
0.001030 |
0.00384 |
0.00787 |
| 2.4 |
251.00 |
0.987 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.5 |
316.00 |
0.987 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.6 |
398.00 |
0.987 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.7 |
501.00 |
0.987 |
0.00572 |
0.001020 |
0.00373 |
0.00771 |
| 2.8 |
631.00 |
0.981 |
0.00575 |
0.001020 |
0.00374 |
0.00775 |
| 2.9 |
794.00 |
0.981 |
0.00575 |
0.001020 |
0.00374 |
0.00775 |
| 3.0 |
1000.00 |
0.981 |
0.00560 |
0.001010 |
0.00363 |
0.00758 |
| 3.1 |
1260.00 |
0.976 |
0.00564 |
0.001010 |
0.00366 |
0.00762 |
| 3.2 |
1580.00 |
0.976 |
0.00549 |
0.000996 |
0.00354 |
0.00744 |
| 3.3 |
2000.00 |
0.967 |
0.00540 |
0.000990 |
0.00346 |
0.00734 |
| 3.4 |
2510.00 |
0.963 |
0.00542 |
0.000994 |
0.00347 |
0.00737 |
| 3.5 |
3160.00 |
0.963 |
0.00527 |
0.000978 |
0.00335 |
0.00719 |
| 3.6 |
3980.00 |
0.956 |
0.00515 |
0.000968 |
0.00325 |
0.00705 |
| 3.7 |
5010.00 |
0.940 |
0.00479 |
0.000939 |
0.00295 |
0.00663 |
| 3.8 |
6310.00 |
0.922 |
0.00487 |
0.000956 |
0.00300 |
0.00675 |
| 3.9 |
7940.00 |
0.912 |
0.00493 |
0.000969 |
0.00303 |
0.00683 |
| 4.0 |
10000.00 |
0.830 |
0.00507 |
0.001030 |
0.00305 |
0.00710 |
| 4.1 |
12600.00 |
0.746 |
0.00544 |
0.001130 |
0.00322 |
0.00766 |
| 4.2 |
15800.00 |
0.673 |
0.00541 |
0.001190 |
0.00307 |
0.00775 |
| 4.3 |
20000.00 |
0.550 |
0.00593 |
0.001410 |
0.00317 |
0.00868 |
| 4.4 |
25100.00 |
0.323 |
0.00536 |
0.001870 |
0.00170 |
0.00903 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.225 |
0.164 |
-0.096900 |
0.548 |
| 0.1 |
0.997 |
1.26 |
0.225 |
0.175 |
-0.117000 |
0.568 |
| 0.2 |
0.997 |
1.58 |
0.225 |
0.175 |
-0.117000 |
0.568 |
| 0.3 |
0.997 |
2.00 |
0.225 |
0.175 |
-0.117000 |
0.568 |
| 0.4 |
0.997 |
2.51 |
0.225 |
0.175 |
-0.117000 |
0.568 |
| 0.5 |
0.997 |
3.16 |
0.225 |
0.175 |
-0.117000 |
0.568 |
| 0.6 |
0.995 |
3.98 |
0.225 |
0.175 |
-0.117000 |
0.568 |
| 0.7 |
0.994 |
5.01 |
0.225 |
0.175 |
-0.118000 |
0.568 |
| 0.8 |
0.994 |
6.31 |
0.225 |
0.175 |
-0.118000 |
0.568 |
| 0.9 |
0.992 |
7.94 |
0.225 |
0.175 |
-0.118000 |
0.569 |
| 1.0 |
0.992 |
10.00 |
0.225 |
0.175 |
-0.118000 |
0.569 |
| 1.1 |
0.992 |
12.60 |
0.225 |
0.175 |
-0.118000 |
0.569 |
| 1.2 |
0.992 |
15.80 |
0.225 |
0.175 |
-0.118000 |
0.569 |
| 1.3 |
0.992 |
20.00 |
0.241 |
0.172 |
-0.096000 |
0.579 |
| 1.4 |
0.992 |
25.10 |
0.241 |
0.172 |
-0.096000 |
0.579 |
| 1.5 |
0.992 |
31.60 |
0.241 |
0.172 |
-0.096000 |
0.579 |
| 1.6 |
0.990 |
39.80 |
0.241 |
0.172 |
-0.096400 |
0.579 |
| 1.7 |
0.990 |
50.10 |
0.241 |
0.172 |
-0.096400 |
0.579 |
| 1.8 |
0.990 |
63.10 |
0.241 |
0.172 |
-0.096400 |
0.579 |
| 1.9 |
0.990 |
79.40 |
0.241 |
0.172 |
-0.096400 |
0.579 |
| 2.0 |
0.990 |
100.00 |
0.241 |
0.172 |
-0.096400 |
0.579 |
| 2.1 |
0.990 |
126.00 |
0.241 |
0.172 |
-0.096400 |
0.579 |
| 2.2 |
0.990 |
158.00 |
0.241 |
0.172 |
-0.096400 |
0.579 |
| 2.3 |
0.989 |
200.00 |
0.241 |
0.173 |
-0.096900 |
0.580 |
| 2.4 |
0.987 |
251.00 |
0.256 |
0.170 |
-0.076900 |
0.589 |
| 2.5 |
0.987 |
316.00 |
0.256 |
0.170 |
-0.076900 |
0.589 |
| 2.6 |
0.987 |
398.00 |
0.256 |
0.170 |
-0.076900 |
0.589 |
| 2.7 |
0.987 |
501.00 |
0.256 |
0.170 |
-0.076900 |
0.589 |
| 2.8 |
0.981 |
631.00 |
0.256 |
0.171 |
-0.078000 |
0.590 |
| 2.9 |
0.981 |
794.00 |
0.256 |
0.171 |
-0.078000 |
0.590 |
| 3.0 |
0.981 |
1000.00 |
0.270 |
0.168 |
-0.058700 |
0.599 |
| 3.1 |
0.976 |
1260.00 |
0.270 |
0.168 |
-0.059600 |
0.600 |
| 3.2 |
0.976 |
1580.00 |
0.287 |
0.165 |
-0.037100 |
0.611 |
| 3.3 |
0.967 |
2000.00 |
0.298 |
0.164 |
-0.023000 |
0.619 |
| 3.4 |
0.963 |
2510.00 |
0.298 |
0.164 |
-0.023800 |
0.619 |
| 3.5 |
0.963 |
3160.00 |
0.316 |
0.161 |
0.000465 |
0.631 |
| 3.6 |
0.956 |
3980.00 |
0.327 |
0.159 |
0.015300 |
0.638 |
| 3.7 |
0.940 |
5010.00 |
0.327 |
0.156 |
0.021300 |
0.632 |
| 3.8 |
0.922 |
6310.00 |
0.327 |
0.158 |
0.017800 |
0.636 |
| 3.9 |
0.912 |
7940.00 |
0.327 |
0.159 |
0.015200 |
0.638 |
| 4.0 |
0.830 |
10000.00 |
0.327 |
0.166 |
0.002090 |
0.651 |
| 4.1 |
0.746 |
12600.00 |
0.327 |
0.176 |
-0.019100 |
0.673 |
| 4.2 |
0.673 |
15800.00 |
0.327 |
0.183 |
-0.031900 |
0.685 |
| 4.3 |
0.550 |
20000.00 |
0.327 |
0.207 |
-0.078800 |
0.732 |
| 4.4 |
0.323 |
25100.00 |
0.327 |
0.262 |
-0.186000 |
0.839 |
IgG3_A244D11K169
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00596 |
0.000929 |
0.004140 |
0.00778 |
| 0.1 |
0.9940 |
1.26 |
0.00596 |
0.001040 |
0.003930 |
0.00799 |
| 0.2 |
0.9940 |
1.58 |
0.00586 |
0.001020 |
0.003850 |
0.00786 |
| 0.3 |
0.9940 |
2.00 |
0.00586 |
0.001020 |
0.003850 |
0.00786 |
| 0.4 |
0.9890 |
2.51 |
0.00586 |
0.001030 |
0.003840 |
0.00787 |
| 0.5 |
0.9880 |
3.16 |
0.00586 |
0.001030 |
0.003840 |
0.00788 |
| 0.6 |
0.9880 |
3.98 |
0.00586 |
0.001030 |
0.003840 |
0.00788 |
| 0.7 |
0.9860 |
5.01 |
0.00584 |
0.001020 |
0.003850 |
0.00783 |
| 0.8 |
0.9790 |
6.31 |
0.00584 |
0.001010 |
0.003870 |
0.00781 |
| 0.9 |
0.9790 |
7.94 |
0.00584 |
0.001010 |
0.003870 |
0.00781 |
| 1.0 |
0.9790 |
10.00 |
0.00584 |
0.001010 |
0.003870 |
0.00781 |
| 1.1 |
0.9670 |
12.60 |
0.00584 |
0.001020 |
0.003850 |
0.00784 |
| 1.2 |
0.9610 |
15.80 |
0.00584 |
0.001030 |
0.003830 |
0.00785 |
| 1.3 |
0.9520 |
20.00 |
0.00584 |
0.001020 |
0.003840 |
0.00784 |
| 1.4 |
0.9390 |
25.10 |
0.00584 |
0.001040 |
0.003810 |
0.00787 |
| 1.5 |
0.9200 |
31.60 |
0.00584 |
0.001060 |
0.003770 |
0.00791 |
| 1.6 |
0.9040 |
39.80 |
0.00584 |
0.001080 |
0.003730 |
0.00795 |
| 1.7 |
0.8800 |
50.10 |
0.00584 |
0.001090 |
0.003710 |
0.00798 |
| 1.8 |
0.8500 |
63.10 |
0.00584 |
0.001090 |
0.003700 |
0.00798 |
| 1.9 |
0.8010 |
79.40 |
0.00584 |
0.001150 |
0.003600 |
0.00809 |
| 2.0 |
0.7590 |
100.00 |
0.00584 |
0.001120 |
0.003640 |
0.00804 |
| 2.1 |
0.6720 |
126.00 |
0.00584 |
0.001150 |
0.003590 |
0.00809 |
| 2.2 |
0.5800 |
158.00 |
0.00584 |
0.001290 |
0.003320 |
0.00837 |
| 2.3 |
0.4950 |
200.00 |
0.00584 |
0.001550 |
0.002800 |
0.00888 |
| 2.4 |
0.3620 |
251.00 |
0.00584 |
0.001730 |
0.002440 |
0.00924 |
| 2.5 |
0.2880 |
316.00 |
0.00584 |
0.002090 |
0.001740 |
0.00995 |
| 2.6 |
0.2260 |
398.00 |
0.00584 |
0.002380 |
0.001180 |
0.01050 |
| 2.7 |
0.1860 |
501.00 |
0.00584 |
0.002690 |
0.000562 |
0.01110 |
| 2.8 |
0.1310 |
631.00 |
0.00584 |
0.003070 |
-0.000173 |
0.01190 |
| 2.9 |
0.0839 |
794.00 |
0.00584 |
0.004060 |
-0.002120 |
0.01380 |
| 3.0 |
0.0608 |
1000.00 |
0.00584 |
0.006410 |
-0.006720 |
0.01840 |
| 3.1 |
0.0519 |
1260.00 |
0.00584 |
0.006030 |
-0.005980 |
0.01770 |
| 3.2 |
0.0462 |
1580.00 |
0.00584 |
0.009500 |
-0.012800 |
0.02450 |
| 3.3 |
0.0285 |
2000.00 |
0.00584 |
0.024500 |
-0.042300 |
0.05390 |
| 3.4 |
0.0183 |
2510.00 |
0.00584 |
0.035600 |
-0.063800 |
0.07550 |
| 3.5 |
0.0093 |
3160.00 |
0.00584 |
0.049700 |
-0.091600 |
0.10300 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9940 |
0.00597 |
0.001040 |
0.003940 |
0.00801 |
| 0.2 |
1.58 |
0.9940 |
0.00583 |
0.001020 |
0.003820 |
0.00783 |
| 0.3 |
2.00 |
0.9940 |
0.00583 |
0.001020 |
0.003820 |
0.00783 |
| 0.4 |
2.51 |
0.9890 |
0.00587 |
0.001030 |
0.003850 |
0.00788 |
| 0.5 |
3.16 |
0.9880 |
0.00588 |
0.001030 |
0.003860 |
0.00790 |
| 0.6 |
3.98 |
0.9880 |
0.00588 |
0.001030 |
0.003860 |
0.00790 |
| 0.7 |
5.01 |
0.9860 |
0.00574 |
0.001020 |
0.003750 |
0.00773 |
| 0.8 |
6.31 |
0.9790 |
0.00562 |
0.001010 |
0.003650 |
0.00760 |
| 0.9 |
7.94 |
0.9790 |
0.00562 |
0.001010 |
0.003650 |
0.00760 |
| 1.0 |
10.00 |
0.9790 |
0.00562 |
0.001010 |
0.003650 |
0.00760 |
| 1.1 |
12.60 |
0.9670 |
0.00568 |
0.001020 |
0.003680 |
0.00768 |
| 1.2 |
15.80 |
0.9610 |
0.00573 |
0.001030 |
0.003710 |
0.00774 |
| 1.3 |
20.00 |
0.9520 |
0.00562 |
0.001020 |
0.003620 |
0.00762 |
| 1.4 |
25.10 |
0.9390 |
0.00571 |
0.001040 |
0.003680 |
0.00774 |
| 1.5 |
31.60 |
0.9200 |
0.00581 |
0.001060 |
0.003740 |
0.00788 |
| 1.6 |
39.80 |
0.9040 |
0.00591 |
0.001080 |
0.003800 |
0.00802 |
| 1.7 |
50.10 |
0.8800 |
0.00590 |
0.001090 |
0.003770 |
0.00804 |
| 1.8 |
63.10 |
0.8500 |
0.00576 |
0.001090 |
0.003620 |
0.00790 |
| 1.9 |
79.40 |
0.8010 |
0.00595 |
0.001150 |
0.003700 |
0.00819 |
| 2.0 |
100.00 |
0.7590 |
0.00549 |
0.001120 |
0.003290 |
0.00769 |
| 2.1 |
126.00 |
0.6720 |
0.00512 |
0.001150 |
0.002870 |
0.00738 |
| 2.2 |
158.00 |
0.5800 |
0.00545 |
0.001290 |
0.002920 |
0.00797 |
| 2.3 |
200.00 |
0.4950 |
0.00633 |
0.001550 |
0.003290 |
0.00937 |
| 2.4 |
251.00 |
0.3620 |
0.00599 |
0.001730 |
0.002600 |
0.00939 |
| 2.5 |
316.00 |
0.2880 |
0.00684 |
0.002090 |
0.002740 |
0.01090 |
| 2.6 |
398.00 |
0.2260 |
0.00716 |
0.002380 |
0.002490 |
0.01180 |
| 2.7 |
501.00 |
0.1860 |
0.00737 |
0.002690 |
0.002100 |
0.01270 |
| 2.8 |
631.00 |
0.1310 |
0.00692 |
0.003070 |
0.000906 |
0.01290 |
| 2.9 |
794.00 |
0.0839 |
0.00811 |
0.004060 |
0.000158 |
0.01610 |
| 3.0 |
1000.00 |
0.0608 |
0.00982 |
0.006410 |
-0.002740 |
0.02240 |
| 3.1 |
1260.00 |
0.0519 |
0.00935 |
0.006030 |
-0.002470 |
0.02120 |
| 3.2 |
1580.00 |
0.0462 |
0.01210 |
0.009500 |
-0.006540 |
0.03070 |
| 3.3 |
2000.00 |
0.0285 |
0.03600 |
0.024500 |
-0.012100 |
0.08410 |
| 3.4 |
2510.00 |
0.0183 |
0.07070 |
0.035600 |
0.001010 |
0.14000 |
| 3.5 |
3160.00 |
0.0093 |
0.14500 |
0.049700 |
0.047300 |
0.24200 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.226 |
0.164 |
-0.0960 |
0.548 |
| 0.1 |
0.9940 |
1.26 |
0.226 |
0.175 |
-0.1170 |
0.569 |
| 0.2 |
0.9940 |
1.58 |
0.240 |
0.172 |
-0.0982 |
0.577 |
| 0.3 |
0.9940 |
2.00 |
0.240 |
0.172 |
-0.0982 |
0.577 |
| 0.4 |
0.9890 |
2.51 |
0.240 |
0.173 |
-0.0991 |
0.578 |
| 0.5 |
0.9880 |
3.16 |
0.240 |
0.173 |
-0.0995 |
0.579 |
| 0.6 |
0.9880 |
3.98 |
0.240 |
0.173 |
-0.0995 |
0.579 |
| 0.7 |
0.9860 |
5.01 |
0.242 |
0.171 |
-0.0944 |
0.577 |
| 0.8 |
0.9790 |
6.31 |
0.242 |
0.170 |
-0.0926 |
0.576 |
| 0.9 |
0.9790 |
7.94 |
0.242 |
0.170 |
-0.0926 |
0.576 |
| 1.0 |
0.9790 |
10.00 |
0.242 |
0.170 |
-0.0926 |
0.576 |
| 1.1 |
0.9670 |
12.60 |
0.242 |
0.172 |
-0.0948 |
0.578 |
| 1.2 |
0.9610 |
15.80 |
0.242 |
0.173 |
-0.0966 |
0.580 |
| 1.3 |
0.9520 |
20.00 |
0.242 |
0.172 |
-0.0950 |
0.578 |
| 1.4 |
0.9390 |
25.10 |
0.242 |
0.173 |
-0.0984 |
0.581 |
| 1.5 |
0.9200 |
31.60 |
0.242 |
0.175 |
-0.1020 |
0.585 |
| 1.6 |
0.9040 |
39.80 |
0.242 |
0.177 |
-0.1060 |
0.589 |
| 1.7 |
0.8800 |
50.10 |
0.242 |
0.179 |
-0.1090 |
0.592 |
| 1.8 |
0.8500 |
63.10 |
0.242 |
0.179 |
-0.1090 |
0.592 |
| 1.9 |
0.8010 |
79.40 |
0.242 |
0.185 |
-0.1200 |
0.603 |
| 2.0 |
0.7590 |
100.00 |
0.242 |
0.182 |
-0.1160 |
0.599 |
| 2.1 |
0.6720 |
126.00 |
0.242 |
0.185 |
-0.1210 |
0.604 |
| 2.2 |
0.5800 |
158.00 |
0.242 |
0.200 |
-0.1500 |
0.633 |
| 2.3 |
0.4950 |
200.00 |
0.242 |
0.229 |
-0.2080 |
0.691 |
| 2.4 |
0.3620 |
251.00 |
0.242 |
0.250 |
-0.2490 |
0.732 |
| 2.5 |
0.2880 |
316.00 |
0.242 |
0.293 |
-0.3330 |
0.816 |
| 2.6 |
0.2260 |
398.00 |
0.242 |
0.328 |
-0.4010 |
0.884 |
| 2.7 |
0.1860 |
501.00 |
0.242 |
0.366 |
-0.4770 |
0.960 |
| 2.8 |
0.1310 |
631.00 |
0.242 |
0.413 |
-0.5680 |
1.050 |
| 2.9 |
0.0839 |
794.00 |
0.242 |
0.538 |
-0.8140 |
1.300 |
| 3.0 |
0.0608 |
1000.00 |
0.242 |
0.839 |
-1.4000 |
1.890 |
| 3.1 |
0.0519 |
1260.00 |
0.242 |
0.791 |
-1.3100 |
1.790 |
| 3.2 |
0.0462 |
1580.00 |
0.242 |
1.240 |
-2.1900 |
2.670 |
| 3.3 |
0.0285 |
2000.00 |
0.242 |
3.190 |
-6.0100 |
6.490 |
| 3.4 |
0.0183 |
2510.00 |
0.242 |
4.620 |
-8.8100 |
9.290 |
| 3.5 |
0.0093 |
3160.00 |
0.242 |
6.450 |
-12.4000 |
12.900 |
IgG3_gp70ClAEV1V2
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| 0.1 |
0.9850 |
1.26 |
0.00582 |
0.001010 |
0.003830 |
0.00780 |
| 0.2 |
0.9850 |
1.58 |
0.00582 |
0.001010 |
0.003830 |
0.00780 |
| 0.3 |
0.9850 |
2.00 |
0.00582 |
0.001010 |
0.003830 |
0.00780 |
| 0.4 |
0.9830 |
2.51 |
0.00582 |
0.001010 |
0.003830 |
0.00781 |
| 0.5 |
0.9820 |
3.16 |
0.00582 |
0.001020 |
0.003830 |
0.00781 |
| 0.6 |
0.9820 |
3.98 |
0.00582 |
0.001020 |
0.003830 |
0.00781 |
| 0.7 |
0.9820 |
5.01 |
0.00582 |
0.001020 |
0.003830 |
0.00781 |
| 0.8 |
0.9770 |
6.31 |
0.00582 |
0.001020 |
0.003820 |
0.00782 |
| 0.9 |
0.9730 |
7.94 |
0.00582 |
0.001030 |
0.003810 |
0.00783 |
| 1.0 |
0.9730 |
10.00 |
0.00582 |
0.001030 |
0.003810 |
0.00783 |
| 1.1 |
0.9660 |
12.60 |
0.00582 |
0.001030 |
0.003800 |
0.00784 |
| 1.2 |
0.9660 |
15.80 |
0.00582 |
0.001030 |
0.003800 |
0.00784 |
| 1.3 |
0.9660 |
20.00 |
0.00582 |
0.001030 |
0.003800 |
0.00784 |
| 1.4 |
0.9660 |
25.10 |
0.00582 |
0.001030 |
0.003800 |
0.00784 |
| 1.5 |
0.9620 |
31.60 |
0.00582 |
0.001030 |
0.003790 |
0.00785 |
| 1.6 |
0.9510 |
39.80 |
0.00582 |
0.001020 |
0.003830 |
0.00781 |
| 1.7 |
0.9470 |
50.10 |
0.00582 |
0.001020 |
0.003820 |
0.00782 |
| 1.8 |
0.9450 |
63.10 |
0.00582 |
0.001020 |
0.003820 |
0.00782 |
| 1.9 |
0.9360 |
79.40 |
0.00582 |
0.001030 |
0.003790 |
0.00785 |
| 2.0 |
0.9290 |
100.00 |
0.00582 |
0.001040 |
0.003780 |
0.00786 |
| 2.1 |
0.9100 |
126.00 |
0.00582 |
0.001030 |
0.003800 |
0.00784 |
| 2.2 |
0.8860 |
158.00 |
0.00582 |
0.001060 |
0.003730 |
0.00791 |
| 2.3 |
0.8750 |
200.00 |
0.00582 |
0.001080 |
0.003710 |
0.00793 |
| 2.4 |
0.8610 |
251.00 |
0.00582 |
0.001060 |
0.003750 |
0.00789 |
| 2.5 |
0.8310 |
316.00 |
0.00582 |
0.001070 |
0.003710 |
0.00792 |
| 2.6 |
0.8040 |
398.00 |
0.00582 |
0.001100 |
0.003670 |
0.00797 |
| 2.7 |
0.7140 |
501.00 |
0.00582 |
0.001190 |
0.003480 |
0.00816 |
| 2.8 |
0.6780 |
631.00 |
0.00582 |
0.001220 |
0.003420 |
0.00822 |
| 2.9 |
0.6350 |
794.00 |
0.00582 |
0.001260 |
0.003350 |
0.00829 |
| 3.0 |
0.5780 |
1000.00 |
0.00582 |
0.001360 |
0.003160 |
0.00848 |
| 3.1 |
0.5070 |
1260.00 |
0.00582 |
0.001470 |
0.002930 |
0.00871 |
| 3.2 |
0.4410 |
1580.00 |
0.00582 |
0.001640 |
0.002600 |
0.00904 |
| 3.3 |
0.3480 |
2000.00 |
0.00582 |
0.001840 |
0.002220 |
0.00942 |
| 3.4 |
0.3030 |
2510.00 |
0.00582 |
0.002060 |
0.001790 |
0.00985 |
| 3.5 |
0.2460 |
3160.00 |
0.00582 |
0.002450 |
0.001010 |
0.01060 |
| 3.6 |
0.1980 |
3980.00 |
0.00582 |
0.002820 |
0.000283 |
0.01140 |
| 3.7 |
0.1560 |
5010.00 |
0.00582 |
0.003560 |
-0.001160 |
0.01280 |
| 3.8 |
0.1080 |
6310.00 |
0.00582 |
0.004320 |
-0.002640 |
0.01430 |
| 3.9 |
0.0747 |
7940.00 |
0.00582 |
0.005710 |
-0.005380 |
0.01700 |
| 4.0 |
0.0655 |
10000.00 |
0.00582 |
0.006590 |
-0.007100 |
0.01870 |
| 4.1 |
0.0609 |
12600.00 |
0.00582 |
0.005650 |
-0.005260 |
0.01690 |
| 4.2 |
0.0451 |
15800.00 |
0.00582 |
0.007840 |
-0.009540 |
0.02120 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9850 |
0.00572 |
0.001010 |
0.003730 |
0.00770 |
| 0.2 |
1.58 |
0.9850 |
0.00572 |
0.001010 |
0.003730 |
0.00770 |
| 0.3 |
2.00 |
0.9850 |
0.00572 |
0.001010 |
0.003730 |
0.00770 |
| 0.4 |
2.51 |
0.9830 |
0.00573 |
0.001010 |
0.003740 |
0.00771 |
| 0.5 |
3.16 |
0.9820 |
0.00573 |
0.001020 |
0.003740 |
0.00772 |
| 0.6 |
3.98 |
0.9820 |
0.00573 |
0.001020 |
0.003740 |
0.00772 |
| 0.7 |
5.01 |
0.9820 |
0.00573 |
0.001020 |
0.003740 |
0.00772 |
| 0.8 |
6.31 |
0.9770 |
0.00576 |
0.001020 |
0.003760 |
0.00776 |
| 0.9 |
7.94 |
0.9730 |
0.00578 |
0.001030 |
0.003770 |
0.00779 |
| 1.0 |
10.00 |
0.9730 |
0.00578 |
0.001030 |
0.003770 |
0.00779 |
| 1.1 |
12.60 |
0.9660 |
0.00581 |
0.001030 |
0.003790 |
0.00784 |
| 1.2 |
15.80 |
0.9660 |
0.00581 |
0.001030 |
0.003790 |
0.00784 |
| 1.3 |
20.00 |
0.9660 |
0.00581 |
0.001030 |
0.003790 |
0.00784 |
| 1.4 |
25.10 |
0.9660 |
0.00581 |
0.001030 |
0.003790 |
0.00784 |
| 1.5 |
31.60 |
0.9620 |
0.00583 |
0.001030 |
0.003810 |
0.00786 |
| 1.6 |
39.80 |
0.9510 |
0.00560 |
0.001020 |
0.003610 |
0.00759 |
| 1.7 |
50.10 |
0.9470 |
0.00562 |
0.001020 |
0.003620 |
0.00762 |
| 1.8 |
63.10 |
0.9450 |
0.00563 |
0.001020 |
0.003630 |
0.00763 |
| 1.9 |
79.40 |
0.9360 |
0.00569 |
0.001030 |
0.003670 |
0.00772 |
| 2.0 |
100.00 |
0.9290 |
0.00573 |
0.001040 |
0.003690 |
0.00777 |
| 2.1 |
126.00 |
0.9100 |
0.00553 |
0.001030 |
0.003510 |
0.00755 |
| 2.2 |
158.00 |
0.8860 |
0.00569 |
0.001060 |
0.003610 |
0.00778 |
| 2.3 |
200.00 |
0.8750 |
0.00575 |
0.001080 |
0.003640 |
0.00786 |
| 2.4 |
251.00 |
0.8610 |
0.00551 |
0.001060 |
0.003440 |
0.00758 |
| 2.5 |
316.00 |
0.8310 |
0.00550 |
0.001070 |
0.003400 |
0.00761 |
| 2.6 |
398.00 |
0.8040 |
0.00553 |
0.001100 |
0.003380 |
0.00768 |
| 2.7 |
501.00 |
0.7140 |
0.00567 |
0.001190 |
0.003330 |
0.00802 |
| 2.8 |
631.00 |
0.6780 |
0.00574 |
0.001220 |
0.003340 |
0.00813 |
| 2.9 |
794.00 |
0.6350 |
0.00570 |
0.001260 |
0.003220 |
0.00817 |
| 3.0 |
1000.00 |
0.5780 |
0.00597 |
0.001360 |
0.003320 |
0.00863 |
| 3.1 |
1260.00 |
0.5070 |
0.00607 |
0.001470 |
0.003190 |
0.00896 |
| 3.2 |
1580.00 |
0.4410 |
0.00642 |
0.001640 |
0.003200 |
0.00965 |
| 3.3 |
2000.00 |
0.3480 |
0.00636 |
0.001840 |
0.002760 |
0.00996 |
| 3.4 |
2510.00 |
0.3030 |
0.00660 |
0.002060 |
0.002560 |
0.01060 |
| 3.5 |
3160.00 |
0.2460 |
0.00738 |
0.002450 |
0.002580 |
0.01220 |
| 3.6 |
3980.00 |
0.1980 |
0.00783 |
0.002820 |
0.002300 |
0.01340 |
| 3.7 |
5010.00 |
0.1560 |
0.00926 |
0.003560 |
0.002280 |
0.01620 |
| 3.8 |
6310.00 |
0.1080 |
0.00960 |
0.004320 |
0.001130 |
0.01810 |
| 3.9 |
7940.00 |
0.0747 |
0.01150 |
0.005710 |
0.000331 |
0.02270 |
| 4.0 |
10000.00 |
0.0655 |
0.01110 |
0.006590 |
-0.001830 |
0.02400 |
| 4.1 |
12600.00 |
0.0609 |
0.00847 |
0.005650 |
-0.002610 |
0.01950 |
| 4.2 |
15800.00 |
0.0451 |
0.01110 |
0.007840 |
-0.004290 |
0.02640 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.228 |
0.164 |
-0.0942 |
0.549 |
| 0.1 |
0.9850 |
1.26 |
0.244 |
0.171 |
-0.0904 |
0.579 |
| 0.2 |
0.9850 |
1.58 |
0.244 |
0.171 |
-0.0904 |
0.579 |
| 0.3 |
0.9850 |
2.00 |
0.244 |
0.171 |
-0.0904 |
0.579 |
| 0.4 |
0.9830 |
2.51 |
0.244 |
0.171 |
-0.0906 |
0.579 |
| 0.5 |
0.9820 |
3.16 |
0.244 |
0.171 |
-0.0909 |
0.580 |
| 0.6 |
0.9820 |
3.98 |
0.244 |
0.171 |
-0.0909 |
0.580 |
| 0.7 |
0.9820 |
5.01 |
0.244 |
0.171 |
-0.0909 |
0.580 |
| 0.8 |
0.9770 |
6.31 |
0.244 |
0.172 |
-0.0919 |
0.581 |
| 0.9 |
0.9730 |
7.94 |
0.244 |
0.172 |
-0.0929 |
0.582 |
| 1.0 |
0.9730 |
10.00 |
0.244 |
0.172 |
-0.0929 |
0.582 |
| 1.1 |
0.9660 |
12.60 |
0.244 |
0.173 |
-0.0942 |
0.583 |
| 1.2 |
0.9660 |
15.80 |
0.244 |
0.173 |
-0.0942 |
0.583 |
| 1.3 |
0.9660 |
20.00 |
0.244 |
0.173 |
-0.0942 |
0.583 |
| 1.4 |
0.9660 |
25.10 |
0.244 |
0.173 |
-0.0942 |
0.583 |
| 1.5 |
0.9620 |
31.60 |
0.244 |
0.173 |
-0.0947 |
0.583 |
| 1.6 |
0.9510 |
39.80 |
0.244 |
0.171 |
-0.0910 |
0.580 |
| 1.7 |
0.9470 |
50.10 |
0.244 |
0.172 |
-0.0919 |
0.581 |
| 1.8 |
0.9450 |
63.10 |
0.244 |
0.172 |
-0.0923 |
0.581 |
| 1.9 |
0.9360 |
79.40 |
0.244 |
0.173 |
-0.0947 |
0.583 |
| 2.0 |
0.9290 |
100.00 |
0.244 |
0.174 |
-0.0960 |
0.585 |
| 2.1 |
0.9100 |
126.00 |
0.244 |
0.173 |
-0.0940 |
0.583 |
| 2.2 |
0.8860 |
158.00 |
0.244 |
0.176 |
-0.1010 |
0.589 |
| 2.3 |
0.8750 |
200.00 |
0.244 |
0.177 |
-0.1030 |
0.592 |
| 2.4 |
0.8610 |
251.00 |
0.244 |
0.175 |
-0.0993 |
0.588 |
| 2.5 |
0.8310 |
316.00 |
0.244 |
0.177 |
-0.1030 |
0.591 |
| 2.6 |
0.8040 |
398.00 |
0.244 |
0.179 |
-0.1070 |
0.596 |
| 2.7 |
0.7140 |
501.00 |
0.244 |
0.190 |
-0.1270 |
0.616 |
| 2.8 |
0.6780 |
631.00 |
0.244 |
0.193 |
-0.1330 |
0.622 |
| 2.9 |
0.6350 |
794.00 |
0.244 |
0.197 |
-0.1410 |
0.630 |
| 3.0 |
0.5780 |
1000.00 |
0.244 |
0.207 |
-0.1610 |
0.650 |
| 3.1 |
0.5070 |
1260.00 |
0.244 |
0.220 |
-0.1870 |
0.676 |
| 3.2 |
0.4410 |
1580.00 |
0.244 |
0.240 |
-0.2260 |
0.714 |
| 3.3 |
0.3480 |
2000.00 |
0.244 |
0.262 |
-0.2700 |
0.758 |
| 3.4 |
0.3030 |
2510.00 |
0.244 |
0.289 |
-0.3210 |
0.810 |
| 3.5 |
0.2460 |
3160.00 |
0.244 |
0.336 |
-0.4150 |
0.904 |
| 3.6 |
0.1980 |
3980.00 |
0.244 |
0.383 |
-0.5060 |
0.994 |
| 3.7 |
0.1560 |
5010.00 |
0.244 |
0.475 |
-0.6870 |
1.180 |
| 3.8 |
0.1080 |
6310.00 |
0.244 |
0.571 |
-0.8750 |
1.360 |
| 3.9 |
0.0747 |
7940.00 |
0.244 |
0.750 |
-1.2300 |
1.710 |
| 4.0 |
0.0655 |
10000.00 |
0.244 |
0.863 |
-1.4500 |
1.940 |
| 4.1 |
0.0609 |
12600.00 |
0.244 |
0.742 |
-1.2100 |
1.700 |
| 4.2 |
0.0451 |
15800.00 |
0.244 |
1.020 |
-1.7600 |
2.250 |
IgG3_gp70V1V2A
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00611 |
0.000929 |
0.004280 |
0.00793 |
| 0.1 |
0.9280 |
1.26 |
0.00611 |
0.001090 |
0.003960 |
0.00825 |
| 0.2 |
0.9200 |
1.58 |
0.00611 |
0.001100 |
0.003950 |
0.00826 |
| 0.3 |
0.9180 |
2.00 |
0.00611 |
0.001100 |
0.003940 |
0.00827 |
| 0.4 |
0.9120 |
2.51 |
0.00607 |
0.001090 |
0.003920 |
0.00821 |
| 0.5 |
0.9100 |
3.16 |
0.00607 |
0.001100 |
0.003920 |
0.00821 |
| 0.6 |
0.8940 |
3.98 |
0.00602 |
0.001090 |
0.003880 |
0.00816 |
| 0.7 |
0.8810 |
5.01 |
0.00602 |
0.001110 |
0.003850 |
0.00819 |
| 0.8 |
0.8640 |
6.31 |
0.00598 |
0.001110 |
0.003810 |
0.00815 |
| 0.9 |
0.8450 |
7.94 |
0.00595 |
0.001120 |
0.003760 |
0.00814 |
| 1.0 |
0.8230 |
10.00 |
0.00548 |
0.001070 |
0.003380 |
0.00758 |
| 1.1 |
0.7770 |
12.60 |
0.00548 |
0.001120 |
0.003280 |
0.00768 |
| 1.2 |
0.7290 |
15.80 |
0.00533 |
0.001100 |
0.003170 |
0.00749 |
| 1.3 |
0.6790 |
20.00 |
0.00533 |
0.001140 |
0.003100 |
0.00756 |
| 1.4 |
0.5720 |
25.10 |
0.00533 |
0.001310 |
0.002770 |
0.00789 |
| 1.5 |
0.5260 |
31.60 |
0.00533 |
0.001340 |
0.002700 |
0.00796 |
| 1.6 |
0.4750 |
39.80 |
0.00533 |
0.001440 |
0.002510 |
0.00815 |
| 1.7 |
0.3890 |
50.10 |
0.00533 |
0.001610 |
0.002170 |
0.00849 |
| 1.8 |
0.3320 |
63.10 |
0.00533 |
0.001360 |
0.002660 |
0.00799 |
| 1.9 |
0.2540 |
79.40 |
0.00533 |
0.001760 |
0.001890 |
0.00877 |
| 2.0 |
0.2230 |
100.00 |
0.00533 |
0.002150 |
0.001120 |
0.00954 |
| 2.1 |
0.1870 |
126.00 |
0.00533 |
0.002260 |
0.000908 |
0.00975 |
| 2.2 |
0.1270 |
158.00 |
0.00533 |
0.003340 |
-0.001210 |
0.01190 |
| 2.3 |
0.1160 |
200.00 |
0.00533 |
0.003320 |
-0.001180 |
0.01180 |
| 2.4 |
0.1020 |
251.00 |
0.00533 |
0.003570 |
-0.001660 |
0.01230 |
| 2.5 |
0.0569 |
316.00 |
0.00533 |
0.008910 |
-0.012100 |
0.02280 |
| 2.6 |
0.0467 |
398.00 |
0.00533 |
0.026800 |
-0.047200 |
0.05780 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9280 |
0.00613 |
0.001090 |
0.003990 |
0.00827 |
| 0.2 |
1.58 |
0.9200 |
0.00617 |
0.001100 |
0.004010 |
0.00833 |
| 0.3 |
2.00 |
0.9180 |
0.00618 |
0.001100 |
0.004020 |
0.00834 |
| 0.4 |
2.51 |
0.9120 |
0.00606 |
0.001090 |
0.003920 |
0.00820 |
| 0.5 |
3.16 |
0.9100 |
0.00607 |
0.001100 |
0.003920 |
0.00822 |
| 0.6 |
3.98 |
0.8940 |
0.00598 |
0.001090 |
0.003840 |
0.00813 |
| 0.7 |
5.01 |
0.8810 |
0.00605 |
0.001110 |
0.003880 |
0.00823 |
| 0.8 |
6.31 |
0.8640 |
0.00598 |
0.001110 |
0.003810 |
0.00815 |
| 0.9 |
7.94 |
0.8450 |
0.00595 |
0.001120 |
0.003760 |
0.00814 |
| 1.0 |
10.00 |
0.8230 |
0.00541 |
0.001070 |
0.003310 |
0.00751 |
| 1.1 |
12.60 |
0.7770 |
0.00555 |
0.001120 |
0.003360 |
0.00775 |
| 1.2 |
15.80 |
0.7290 |
0.00511 |
0.001100 |
0.002950 |
0.00726 |
| 1.3 |
20.00 |
0.6790 |
0.00508 |
0.001140 |
0.002850 |
0.00731 |
| 1.4 |
25.10 |
0.5720 |
0.00543 |
0.001310 |
0.002870 |
0.00799 |
| 1.5 |
31.60 |
0.5260 |
0.00531 |
0.001340 |
0.002680 |
0.00793 |
| 1.6 |
39.80 |
0.4750 |
0.00553 |
0.001440 |
0.002710 |
0.00835 |
| 1.7 |
50.10 |
0.3890 |
0.00562 |
0.001610 |
0.002470 |
0.00878 |
| 1.8 |
63.10 |
0.3320 |
0.00358 |
0.001360 |
0.000915 |
0.00625 |
| 1.9 |
79.40 |
0.2540 |
0.00398 |
0.001760 |
0.000537 |
0.00742 |
| 2.0 |
100.00 |
0.2230 |
0.00481 |
0.002150 |
0.000599 |
0.00901 |
| 2.1 |
126.00 |
0.1870 |
0.00466 |
0.002260 |
0.000240 |
0.00908 |
| 2.2 |
158.00 |
0.1270 |
0.00640 |
0.003340 |
-0.000144 |
0.01290 |
| 2.3 |
200.00 |
0.1160 |
0.00576 |
0.003320 |
-0.000750 |
0.01230 |
| 2.4 |
251.00 |
0.1020 |
0.00539 |
0.003570 |
-0.001600 |
0.01240 |
| 2.5 |
316.00 |
0.0569 |
0.01170 |
0.008910 |
-0.005820 |
0.02910 |
| 2.6 |
398.00 |
0.0467 |
0.02270 |
0.026800 |
-0.029800 |
0.07520 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.207 |
0.166 |
-0.1180 |
0.533 |
| 0.1 |
0.9280 |
1.26 |
0.207 |
0.182 |
-0.1500 |
0.564 |
| 0.2 |
0.9200 |
1.58 |
0.207 |
0.183 |
-0.1520 |
0.566 |
| 0.3 |
0.9180 |
2.00 |
0.207 |
0.183 |
-0.1520 |
0.566 |
| 0.4 |
0.9120 |
2.51 |
0.212 |
0.182 |
-0.1440 |
0.569 |
| 0.5 |
0.9100 |
3.16 |
0.212 |
0.182 |
-0.1440 |
0.569 |
| 0.6 |
0.8940 |
3.98 |
0.218 |
0.181 |
-0.1370 |
0.574 |
| 0.7 |
0.8810 |
5.01 |
0.218 |
0.183 |
-0.1400 |
0.576 |
| 0.8 |
0.8640 |
6.31 |
0.224 |
0.182 |
-0.1340 |
0.581 |
| 0.9 |
0.8450 |
7.94 |
0.227 |
0.183 |
-0.1310 |
0.586 |
| 1.0 |
0.8230 |
10.00 |
0.288 |
0.173 |
-0.0503 |
0.627 |
| 1.1 |
0.7770 |
12.60 |
0.288 |
0.178 |
-0.0604 |
0.637 |
| 1.2 |
0.7290 |
15.80 |
0.308 |
0.174 |
-0.0336 |
0.650 |
| 1.3 |
0.6790 |
20.00 |
0.308 |
0.178 |
-0.0414 |
0.657 |
| 1.4 |
0.5720 |
25.10 |
0.308 |
0.197 |
-0.0778 |
0.694 |
| 1.5 |
0.5260 |
31.60 |
0.308 |
0.201 |
-0.0852 |
0.701 |
| 1.6 |
0.4750 |
39.80 |
0.308 |
0.212 |
-0.1070 |
0.723 |
| 1.7 |
0.3890 |
50.10 |
0.308 |
0.232 |
-0.1460 |
0.762 |
| 1.8 |
0.3320 |
63.10 |
0.308 |
0.203 |
-0.0895 |
0.705 |
| 1.9 |
0.2540 |
79.40 |
0.308 |
0.249 |
-0.1800 |
0.796 |
| 2.0 |
0.2230 |
100.00 |
0.308 |
0.296 |
-0.2720 |
0.888 |
| 2.1 |
0.1870 |
126.00 |
0.308 |
0.309 |
-0.2990 |
0.915 |
| 2.2 |
0.1270 |
158.00 |
0.308 |
0.445 |
-0.5640 |
1.180 |
| 2.3 |
0.1160 |
200.00 |
0.308 |
0.442 |
-0.5590 |
1.180 |
| 2.4 |
0.1020 |
251.00 |
0.308 |
0.474 |
-0.6210 |
1.240 |
| 2.5 |
0.0569 |
316.00 |
0.308 |
1.160 |
-1.9700 |
2.580 |
| 2.6 |
0.0467 |
398.00 |
0.308 |
3.480 |
-6.5100 |
7.130 |
IgG3_gp70V1V2AP
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00607 |
0.000929 |
0.004250 |
0.00789 |
| 0.1 |
0.9290 |
1.26 |
0.00607 |
0.001080 |
0.003960 |
0.00818 |
| 0.2 |
0.9290 |
1.58 |
0.00607 |
0.001080 |
0.003960 |
0.00818 |
| 0.3 |
0.9120 |
2.00 |
0.00607 |
0.001100 |
0.003920 |
0.00822 |
| 0.4 |
0.9010 |
2.51 |
0.00607 |
0.001100 |
0.003910 |
0.00823 |
| 0.5 |
0.8970 |
3.16 |
0.00590 |
0.001070 |
0.003790 |
0.00800 |
| 0.6 |
0.8710 |
3.98 |
0.00590 |
0.001100 |
0.003740 |
0.00805 |
| 0.7 |
0.8450 |
5.01 |
0.00590 |
0.001100 |
0.003750 |
0.00805 |
| 0.8 |
0.8290 |
6.31 |
0.00590 |
0.001120 |
0.003690 |
0.00810 |
| 0.9 |
0.7810 |
7.94 |
0.00590 |
0.001160 |
0.003630 |
0.00816 |
| 1.0 |
0.7400 |
10.00 |
0.00590 |
0.001150 |
0.003640 |
0.00816 |
| 1.1 |
0.7020 |
12.60 |
0.00590 |
0.001230 |
0.003480 |
0.00831 |
| 1.2 |
0.6360 |
15.80 |
0.00590 |
0.001340 |
0.003260 |
0.00853 |
| 1.3 |
0.5770 |
20.00 |
0.00590 |
0.001320 |
0.003300 |
0.00849 |
| 1.4 |
0.4680 |
25.10 |
0.00590 |
0.001530 |
0.002900 |
0.00890 |
| 1.5 |
0.4130 |
31.60 |
0.00544 |
0.001510 |
0.002490 |
0.00839 |
| 1.6 |
0.3350 |
39.80 |
0.00530 |
0.001640 |
0.002090 |
0.00851 |
| 1.7 |
0.2870 |
50.10 |
0.00530 |
0.001790 |
0.001790 |
0.00882 |
| 1.8 |
0.2140 |
63.10 |
0.00530 |
0.002290 |
0.000809 |
0.00979 |
| 1.9 |
0.1690 |
79.40 |
0.00530 |
0.003040 |
-0.000663 |
0.01130 |
| 2.0 |
0.1560 |
100.00 |
0.00530 |
0.003180 |
-0.000938 |
0.01150 |
| 2.1 |
0.1420 |
126.00 |
0.00530 |
0.003640 |
-0.001830 |
0.01240 |
| 2.2 |
0.1190 |
158.00 |
0.00530 |
0.004150 |
-0.002830 |
0.01340 |
| 2.3 |
0.0961 |
200.00 |
0.00530 |
0.005210 |
-0.004900 |
0.01550 |
| 2.4 |
0.0758 |
251.00 |
0.00530 |
0.006550 |
-0.007540 |
0.01810 |
| 2.5 |
0.0646 |
316.00 |
0.00530 |
0.004890 |
-0.004290 |
0.01490 |
| 2.6 |
0.0556 |
398.00 |
0.00530 |
0.006500 |
-0.007450 |
0.01810 |
| 2.7 |
0.0455 |
501.00 |
0.00530 |
0.006230 |
-0.006900 |
0.01750 |
| 2.8 |
0.0353 |
631.00 |
0.00530 |
0.009160 |
-0.012700 |
0.02330 |
| 2.9 |
0.0252 |
794.00 |
0.00530 |
0.018100 |
-0.030100 |
0.04070 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9290 |
0.00606 |
0.001080 |
0.003950 |
0.00817 |
| 0.2 |
1.58 |
0.9290 |
0.00606 |
0.001080 |
0.003950 |
0.00817 |
| 0.3 |
2.00 |
0.9120 |
0.00617 |
0.001100 |
0.004020 |
0.00833 |
| 0.4 |
2.51 |
0.9010 |
0.00612 |
0.001100 |
0.003950 |
0.00828 |
| 0.5 |
3.16 |
0.8970 |
0.00581 |
0.001070 |
0.003710 |
0.00791 |
| 0.6 |
3.98 |
0.8710 |
0.00594 |
0.001100 |
0.003790 |
0.00810 |
| 0.7 |
5.01 |
0.8450 |
0.00578 |
0.001100 |
0.003630 |
0.00793 |
| 0.8 |
6.31 |
0.8290 |
0.00591 |
0.001120 |
0.003700 |
0.00811 |
| 0.9 |
7.94 |
0.7810 |
0.00587 |
0.001160 |
0.003600 |
0.00813 |
| 1.0 |
10.00 |
0.7400 |
0.00560 |
0.001150 |
0.003340 |
0.00786 |
| 1.1 |
12.60 |
0.7020 |
0.00594 |
0.001230 |
0.003530 |
0.00835 |
| 1.2 |
15.80 |
0.6360 |
0.00634 |
0.001340 |
0.003710 |
0.00898 |
| 1.3 |
20.00 |
0.5770 |
0.00572 |
0.001320 |
0.003120 |
0.00831 |
| 1.4 |
25.10 |
0.4680 |
0.00611 |
0.001530 |
0.003110 |
0.00911 |
| 1.5 |
31.60 |
0.4130 |
0.00544 |
0.001510 |
0.002490 |
0.00839 |
| 1.6 |
39.80 |
0.3350 |
0.00515 |
0.001640 |
0.001940 |
0.00836 |
| 1.7 |
50.10 |
0.2870 |
0.00539 |
0.001790 |
0.001870 |
0.00890 |
| 1.8 |
63.10 |
0.2140 |
0.00616 |
0.002290 |
0.001670 |
0.01070 |
| 1.9 |
79.40 |
0.1690 |
0.00783 |
0.003040 |
0.001870 |
0.01380 |
| 2.0 |
100.00 |
0.1560 |
0.00718 |
0.003180 |
0.000937 |
0.01340 |
| 2.1 |
126.00 |
0.1420 |
0.00759 |
0.003640 |
0.000459 |
0.01470 |
| 2.2 |
158.00 |
0.1190 |
0.00735 |
0.004150 |
-0.000776 |
0.01550 |
| 2.3 |
200.00 |
0.0961 |
0.00877 |
0.005210 |
-0.001430 |
0.01900 |
| 2.4 |
251.00 |
0.0758 |
0.01080 |
0.006550 |
-0.002000 |
0.02370 |
| 2.5 |
316.00 |
0.0646 |
0.00747 |
0.004890 |
-0.002130 |
0.01710 |
| 2.6 |
398.00 |
0.0556 |
0.00727 |
0.006500 |
-0.005480 |
0.02000 |
| 2.7 |
501.00 |
0.0455 |
0.01210 |
0.006230 |
-0.000140 |
0.02430 |
| 2.8 |
631.00 |
0.0353 |
0.01700 |
0.009160 |
-0.000976 |
0.03490 |
| 2.9 |
794.00 |
0.0252 |
0.03020 |
0.018100 |
-0.005190 |
0.06560 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.212 |
0.166 |
-0.113 |
0.537 |
| 0.1 |
0.9290 |
1.26 |
0.212 |
0.180 |
-0.141 |
0.565 |
| 0.2 |
0.9290 |
1.58 |
0.212 |
0.180 |
-0.141 |
0.565 |
| 0.3 |
0.9120 |
2.00 |
0.212 |
0.182 |
-0.146 |
0.569 |
| 0.4 |
0.9010 |
2.51 |
0.212 |
0.183 |
-0.146 |
0.570 |
| 0.5 |
0.8970 |
3.16 |
0.234 |
0.178 |
-0.114 |
0.583 |
| 0.6 |
0.8710 |
3.98 |
0.234 |
0.180 |
-0.119 |
0.588 |
| 0.7 |
0.8450 |
5.01 |
0.234 |
0.180 |
-0.119 |
0.588 |
| 0.8 |
0.8290 |
6.31 |
0.234 |
0.183 |
-0.124 |
0.593 |
| 0.9 |
0.7810 |
7.94 |
0.234 |
0.186 |
-0.131 |
0.599 |
| 1.0 |
0.7400 |
10.00 |
0.234 |
0.186 |
-0.130 |
0.599 |
| 1.1 |
0.7020 |
12.60 |
0.234 |
0.194 |
-0.146 |
0.615 |
| 1.2 |
0.6360 |
15.80 |
0.234 |
0.207 |
-0.171 |
0.639 |
| 1.3 |
0.5770 |
20.00 |
0.234 |
0.204 |
-0.166 |
0.635 |
| 1.4 |
0.4680 |
25.10 |
0.234 |
0.227 |
-0.211 |
0.680 |
| 1.5 |
0.4130 |
31.60 |
0.294 |
0.221 |
-0.138 |
0.726 |
| 1.6 |
0.3350 |
39.80 |
0.312 |
0.235 |
-0.148 |
0.771 |
| 1.7 |
0.2870 |
50.10 |
0.312 |
0.253 |
-0.185 |
0.808 |
| 1.8 |
0.2140 |
63.10 |
0.312 |
0.314 |
-0.303 |
0.927 |
| 1.9 |
0.1690 |
79.40 |
0.312 |
0.407 |
-0.487 |
1.110 |
| 2.0 |
0.1560 |
100.00 |
0.312 |
0.425 |
-0.522 |
1.140 |
| 2.1 |
0.1420 |
126.00 |
0.312 |
0.483 |
-0.634 |
1.260 |
| 2.2 |
0.1190 |
158.00 |
0.312 |
0.548 |
-0.762 |
1.380 |
| 2.3 |
0.0961 |
200.00 |
0.312 |
0.683 |
-1.030 |
1.650 |
| 2.4 |
0.0758 |
251.00 |
0.312 |
0.857 |
-1.370 |
1.990 |
| 2.5 |
0.0646 |
316.00 |
0.312 |
0.643 |
-0.949 |
1.570 |
| 2.6 |
0.0556 |
398.00 |
0.312 |
0.850 |
-1.360 |
1.980 |
| 2.7 |
0.0455 |
501.00 |
0.312 |
0.815 |
-1.290 |
1.910 |
| 2.8 |
0.0353 |
631.00 |
0.312 |
1.190 |
-2.030 |
2.650 |
| 2.9 |
0.0252 |
794.00 |
0.312 |
2.350 |
-4.290 |
4.910 |
IgG3_gp70V1V2C
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| 0.1 |
0.9280 |
1.26 |
0.00529 |
0.000996 |
0.003330 |
0.00724 |
| 0.2 |
0.9260 |
1.58 |
0.00518 |
0.000980 |
0.003260 |
0.00711 |
| 0.3 |
0.9210 |
2.00 |
0.00518 |
0.000984 |
0.003260 |
0.00711 |
| 0.4 |
0.9170 |
2.51 |
0.00518 |
0.000992 |
0.003240 |
0.00713 |
| 0.5 |
0.9100 |
3.16 |
0.00518 |
0.001010 |
0.003210 |
0.00715 |
| 0.6 |
0.8940 |
3.98 |
0.00510 |
0.000991 |
0.003160 |
0.00705 |
| 0.7 |
0.8780 |
5.01 |
0.00510 |
0.001010 |
0.003130 |
0.00707 |
| 0.8 |
0.8540 |
6.31 |
0.00510 |
0.001010 |
0.003120 |
0.00709 |
| 0.9 |
0.8320 |
7.94 |
0.00510 |
0.001020 |
0.003110 |
0.00710 |
| 1.0 |
0.8040 |
10.00 |
0.00510 |
0.001040 |
0.003070 |
0.00714 |
| 1.1 |
0.7570 |
12.60 |
0.00510 |
0.001090 |
0.002970 |
0.00724 |
| 1.2 |
0.7220 |
15.80 |
0.00510 |
0.001100 |
0.002960 |
0.00725 |
| 1.3 |
0.6570 |
20.00 |
0.00510 |
0.001210 |
0.002730 |
0.00748 |
| 1.4 |
0.6130 |
25.10 |
0.00503 |
0.001140 |
0.002790 |
0.00726 |
| 1.5 |
0.5470 |
31.60 |
0.00503 |
0.001290 |
0.002500 |
0.00755 |
| 1.6 |
0.4920 |
39.80 |
0.00503 |
0.001330 |
0.002410 |
0.00764 |
| 1.7 |
0.4430 |
50.10 |
0.00503 |
0.001380 |
0.002320 |
0.00774 |
| 1.8 |
0.3570 |
63.10 |
0.00503 |
0.001640 |
0.001810 |
0.00824 |
| 1.9 |
0.3040 |
79.40 |
0.00503 |
0.001540 |
0.002010 |
0.00804 |
| 2.0 |
0.2730 |
100.00 |
0.00503 |
0.001530 |
0.002030 |
0.00803 |
| 2.1 |
0.2150 |
126.00 |
0.00503 |
0.001880 |
0.001350 |
0.00871 |
| 2.2 |
0.1780 |
158.00 |
0.00503 |
0.002290 |
0.000544 |
0.00951 |
| 2.3 |
0.1270 |
200.00 |
0.00503 |
0.003730 |
-0.002290 |
0.01230 |
| 2.4 |
0.0928 |
251.00 |
0.00503 |
0.004480 |
-0.003750 |
0.01380 |
| 2.5 |
0.0546 |
316.00 |
0.00503 |
0.009350 |
-0.013300 |
0.02340 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9280 |
0.00529 |
0.000996 |
0.003330 |
0.00724 |
| 0.2 |
1.58 |
0.9260 |
0.00514 |
0.000980 |
0.003210 |
0.00706 |
| 0.3 |
2.00 |
0.9210 |
0.00515 |
0.000984 |
0.003220 |
0.00708 |
| 0.4 |
2.51 |
0.9170 |
0.00519 |
0.000992 |
0.003250 |
0.00714 |
| 0.5 |
3.16 |
0.9100 |
0.00526 |
0.001010 |
0.003290 |
0.00723 |
| 0.6 |
3.98 |
0.8940 |
0.00504 |
0.000991 |
0.003090 |
0.00698 |
| 0.7 |
5.01 |
0.8780 |
0.00510 |
0.001010 |
0.003130 |
0.00707 |
| 0.8 |
6.31 |
0.8540 |
0.00506 |
0.001010 |
0.003080 |
0.00704 |
| 0.9 |
7.94 |
0.8320 |
0.00501 |
0.001020 |
0.003010 |
0.00701 |
| 1.0 |
10.00 |
0.8040 |
0.00502 |
0.001040 |
0.002990 |
0.00706 |
| 1.1 |
12.60 |
0.7570 |
0.00515 |
0.001090 |
0.003020 |
0.00728 |
| 1.2 |
15.80 |
0.7220 |
0.00500 |
0.001100 |
0.002850 |
0.00714 |
| 1.3 |
20.00 |
0.6570 |
0.00549 |
0.001210 |
0.003110 |
0.00786 |
| 1.4 |
25.10 |
0.6130 |
0.00466 |
0.001140 |
0.002420 |
0.00689 |
| 1.5 |
31.60 |
0.5470 |
0.00518 |
0.001290 |
0.002650 |
0.00770 |
| 1.6 |
39.80 |
0.4920 |
0.00508 |
0.001330 |
0.002470 |
0.00770 |
| 1.7 |
50.10 |
0.4430 |
0.00496 |
0.001380 |
0.002250 |
0.00767 |
| 1.8 |
63.10 |
0.3570 |
0.00531 |
0.001640 |
0.002100 |
0.00853 |
| 1.9 |
79.40 |
0.3040 |
0.00419 |
0.001540 |
0.001180 |
0.00720 |
| 2.0 |
100.00 |
0.2730 |
0.00372 |
0.001530 |
0.000721 |
0.00672 |
| 2.1 |
126.00 |
0.2150 |
0.00425 |
0.001880 |
0.000565 |
0.00793 |
| 2.2 |
158.00 |
0.1780 |
0.00510 |
0.002290 |
0.000622 |
0.00958 |
| 2.3 |
200.00 |
0.1270 |
0.00798 |
0.003730 |
0.000665 |
0.01530 |
| 2.4 |
251.00 |
0.0928 |
0.00754 |
0.004480 |
-0.001240 |
0.01630 |
| 2.5 |
316.00 |
0.0546 |
0.01220 |
0.009350 |
-0.006170 |
0.03050 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.228 |
0.164 |
-0.09420 |
0.549 |
| 0.1 |
0.9280 |
1.26 |
0.314 |
0.163 |
-0.00556 |
0.633 |
| 0.2 |
0.9260 |
1.58 |
0.327 |
0.160 |
0.01300 |
0.641 |
| 0.3 |
0.9210 |
2.00 |
0.327 |
0.160 |
0.01230 |
0.641 |
| 0.4 |
0.9170 |
2.51 |
0.327 |
0.161 |
0.01070 |
0.643 |
| 0.5 |
0.9100 |
3.16 |
0.327 |
0.163 |
0.00802 |
0.646 |
| 0.6 |
0.8940 |
3.98 |
0.337 |
0.160 |
0.02310 |
0.651 |
| 0.7 |
0.8780 |
5.01 |
0.337 |
0.162 |
0.02010 |
0.654 |
| 0.8 |
0.8540 |
6.31 |
0.337 |
0.163 |
0.01860 |
0.656 |
| 0.9 |
0.8320 |
7.94 |
0.337 |
0.163 |
0.01720 |
0.657 |
| 1.0 |
0.8040 |
10.00 |
0.337 |
0.165 |
0.01290 |
0.662 |
| 1.1 |
0.7570 |
12.60 |
0.337 |
0.171 |
0.00278 |
0.672 |
| 1.2 |
0.7220 |
15.80 |
0.337 |
0.171 |
0.00135 |
0.673 |
| 1.3 |
0.6570 |
20.00 |
0.337 |
0.184 |
-0.02390 |
0.698 |
| 1.4 |
0.6130 |
25.10 |
0.347 |
0.176 |
0.00315 |
0.692 |
| 1.5 |
0.5470 |
31.60 |
0.347 |
0.192 |
-0.02850 |
0.723 |
| 1.6 |
0.4920 |
39.80 |
0.347 |
0.197 |
-0.03900 |
0.734 |
| 1.7 |
0.4430 |
50.10 |
0.347 |
0.203 |
-0.05000 |
0.745 |
| 1.8 |
0.3570 |
63.10 |
0.347 |
0.233 |
-0.10900 |
0.804 |
| 1.9 |
0.3040 |
79.40 |
0.347 |
0.221 |
-0.08490 |
0.780 |
| 2.0 |
0.2730 |
100.00 |
0.347 |
0.220 |
-0.08360 |
0.778 |
| 2.1 |
0.2150 |
126.00 |
0.347 |
0.261 |
-0.16500 |
0.860 |
| 2.2 |
0.1780 |
158.00 |
0.347 |
0.311 |
-0.26300 |
0.958 |
| 2.3 |
0.1270 |
200.00 |
0.347 |
0.493 |
-0.62000 |
1.310 |
| 2.4 |
0.0928 |
251.00 |
0.347 |
0.589 |
-0.80700 |
1.500 |
| 2.5 |
0.0546 |
316.00 |
0.347 |
1.220 |
-2.04000 |
2.730 |
IgG3_gp70.V1V2CaseA2
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| 0.1 |
0.9400 |
1.26 |
0.00571 |
0.001040 |
0.003680 |
0.00775 |
| 0.2 |
0.9400 |
1.58 |
0.00571 |
0.001040 |
0.003680 |
0.00775 |
| 0.3 |
0.9350 |
2.00 |
0.00558 |
0.001030 |
0.003570 |
0.00759 |
| 0.4 |
0.9220 |
2.51 |
0.00555 |
0.001020 |
0.003550 |
0.00756 |
| 0.5 |
0.9080 |
3.16 |
0.00555 |
0.001040 |
0.003520 |
0.00759 |
| 0.6 |
0.8880 |
3.98 |
0.00555 |
0.001050 |
0.003500 |
0.00760 |
| 0.7 |
0.8690 |
5.01 |
0.00555 |
0.001070 |
0.003460 |
0.00765 |
| 0.8 |
0.8530 |
6.31 |
0.00549 |
0.001050 |
0.003420 |
0.00755 |
| 0.9 |
0.8230 |
7.94 |
0.00549 |
0.001090 |
0.003350 |
0.00762 |
| 1.0 |
0.7850 |
10.00 |
0.00545 |
0.001100 |
0.003300 |
0.00761 |
| 1.1 |
0.7310 |
12.60 |
0.00468 |
0.001010 |
0.002690 |
0.00666 |
| 1.2 |
0.6730 |
15.80 |
0.00468 |
0.001080 |
0.002570 |
0.00679 |
| 1.3 |
0.6550 |
20.00 |
0.00468 |
0.001110 |
0.002510 |
0.00685 |
| 1.4 |
0.5890 |
25.10 |
0.00468 |
0.001210 |
0.002300 |
0.00705 |
| 1.5 |
0.4950 |
31.60 |
0.00468 |
0.001280 |
0.002170 |
0.00719 |
| 1.6 |
0.4320 |
39.80 |
0.00468 |
0.001400 |
0.001930 |
0.00742 |
| 1.7 |
0.3540 |
50.10 |
0.00403 |
0.001400 |
0.001280 |
0.00678 |
| 1.8 |
0.3130 |
63.10 |
0.00403 |
0.001420 |
0.001250 |
0.00681 |
| 1.9 |
0.2540 |
79.40 |
0.00403 |
0.001580 |
0.000937 |
0.00712 |
| 2.0 |
0.2240 |
100.00 |
0.00403 |
0.001820 |
0.000460 |
0.00759 |
| 2.1 |
0.1580 |
126.00 |
0.00403 |
0.002630 |
-0.001140 |
0.00919 |
| 2.2 |
0.1150 |
158.00 |
0.00403 |
0.004010 |
-0.003840 |
0.01190 |
| 2.3 |
0.0712 |
200.00 |
0.00403 |
0.006370 |
-0.008460 |
0.01650 |
| 2.4 |
0.0578 |
251.00 |
0.00403 |
0.011200 |
-0.017900 |
0.02590 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9400 |
0.00571 |
0.001040 |
0.003680 |
0.00775 |
| 0.2 |
1.58 |
0.9400 |
0.00571 |
0.001040 |
0.003680 |
0.00775 |
| 0.3 |
2.00 |
0.9350 |
0.00558 |
0.001030 |
0.003570 |
0.00759 |
| 0.4 |
2.51 |
0.9220 |
0.00548 |
0.001020 |
0.003480 |
0.00749 |
| 0.5 |
3.16 |
0.9080 |
0.00556 |
0.001040 |
0.003530 |
0.00759 |
| 0.6 |
3.98 |
0.8880 |
0.00553 |
0.001050 |
0.003480 |
0.00758 |
| 0.7 |
5.01 |
0.8690 |
0.00564 |
0.001070 |
0.003540 |
0.00774 |
| 0.8 |
6.31 |
0.8530 |
0.00541 |
0.001050 |
0.003340 |
0.00747 |
| 0.9 |
7.94 |
0.8230 |
0.00557 |
0.001090 |
0.003430 |
0.00771 |
| 1.0 |
10.00 |
0.7850 |
0.00545 |
0.001100 |
0.003300 |
0.00761 |
| 1.1 |
12.60 |
0.7310 |
0.00446 |
0.001010 |
0.002470 |
0.00645 |
| 1.2 |
15.80 |
0.6730 |
0.00453 |
0.001080 |
0.002420 |
0.00664 |
| 1.3 |
20.00 |
0.6550 |
0.00465 |
0.001110 |
0.002480 |
0.00682 |
| 1.4 |
25.10 |
0.5890 |
0.00494 |
0.001210 |
0.002560 |
0.00732 |
| 1.5 |
31.60 |
0.4950 |
0.00464 |
0.001280 |
0.002130 |
0.00715 |
| 1.6 |
39.80 |
0.4320 |
0.00491 |
0.001400 |
0.002160 |
0.00765 |
| 1.7 |
50.10 |
0.3540 |
0.00400 |
0.001400 |
0.001250 |
0.00675 |
| 1.8 |
63.10 |
0.3130 |
0.00386 |
0.001420 |
0.001080 |
0.00664 |
| 1.9 |
79.40 |
0.2540 |
0.00385 |
0.001580 |
0.000762 |
0.00694 |
| 2.0 |
100.00 |
0.2240 |
0.00436 |
0.001820 |
0.000797 |
0.00793 |
| 2.1 |
126.00 |
0.1580 |
0.00574 |
0.002630 |
0.000580 |
0.01090 |
| 2.2 |
158.00 |
0.1150 |
0.00837 |
0.004010 |
0.000499 |
0.01620 |
| 2.3 |
200.00 |
0.0712 |
0.00974 |
0.006370 |
-0.002740 |
0.02220 |
| 2.4 |
251.00 |
0.0578 |
0.01450 |
0.011200 |
-0.007390 |
0.03640 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.228 |
0.164 |
-0.09420 |
0.549 |
| 0.1 |
0.9400 |
1.26 |
0.258 |
0.172 |
-0.07900 |
0.596 |
| 0.2 |
0.9400 |
1.58 |
0.258 |
0.172 |
-0.07900 |
0.596 |
| 0.3 |
0.9350 |
2.00 |
0.276 |
0.169 |
-0.05600 |
0.608 |
| 0.4 |
0.9220 |
2.51 |
0.279 |
0.169 |
-0.05150 |
0.609 |
| 0.5 |
0.9080 |
3.16 |
0.279 |
0.170 |
-0.05460 |
0.612 |
| 0.6 |
0.8880 |
3.98 |
0.279 |
0.171 |
-0.05650 |
0.614 |
| 0.7 |
0.8690 |
5.01 |
0.279 |
0.174 |
-0.06130 |
0.619 |
| 0.8 |
0.8530 |
6.31 |
0.287 |
0.171 |
-0.04790 |
0.623 |
| 0.9 |
0.8230 |
7.94 |
0.287 |
0.175 |
-0.05540 |
0.630 |
| 1.0 |
0.7850 |
10.00 |
0.292 |
0.176 |
-0.05250 |
0.636 |
| 1.1 |
0.7310 |
12.60 |
0.393 |
0.158 |
0.08290 |
0.703 |
| 1.2 |
0.6730 |
15.80 |
0.393 |
0.165 |
0.06960 |
0.716 |
| 1.3 |
0.6550 |
20.00 |
0.393 |
0.168 |
0.06280 |
0.723 |
| 1.4 |
0.5890 |
25.10 |
0.393 |
0.180 |
0.03960 |
0.746 |
| 1.5 |
0.4950 |
31.60 |
0.393 |
0.188 |
0.02440 |
0.761 |
| 1.6 |
0.4320 |
39.80 |
0.393 |
0.202 |
-0.00308 |
0.789 |
| 1.7 |
0.3540 |
50.10 |
0.477 |
0.197 |
0.09080 |
0.863 |
| 1.8 |
0.3130 |
63.10 |
0.477 |
0.199 |
0.08690 |
0.867 |
| 1.9 |
0.2540 |
79.40 |
0.477 |
0.218 |
0.04940 |
0.905 |
| 2.0 |
0.2240 |
100.00 |
0.477 |
0.248 |
-0.00922 |
0.963 |
| 2.1 |
0.1580 |
126.00 |
0.477 |
0.350 |
-0.21000 |
1.160 |
| 2.2 |
0.1150 |
158.00 |
0.477 |
0.527 |
-0.55500 |
1.510 |
| 2.3 |
0.0712 |
200.00 |
0.477 |
0.830 |
-1.15000 |
2.100 |
| 2.4 |
0.0578 |
251.00 |
0.477 |
1.450 |
-2.37000 |
3.330 |
IgG3_gp70BCaseA2V1V2169K
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| 0.1 |
0.9690 |
1.26 |
0.00544 |
0.000984 |
0.003510 |
0.00737 |
| 0.2 |
0.9690 |
1.58 |
0.00544 |
0.000984 |
0.003510 |
0.00737 |
| 0.3 |
0.9690 |
2.00 |
0.00544 |
0.000984 |
0.003510 |
0.00737 |
| 0.4 |
0.9690 |
2.51 |
0.00544 |
0.000984 |
0.003510 |
0.00737 |
| 0.5 |
0.9680 |
3.16 |
0.00544 |
0.000985 |
0.003510 |
0.00737 |
| 0.6 |
0.9630 |
3.98 |
0.00544 |
0.000989 |
0.003500 |
0.00738 |
| 0.7 |
0.9570 |
5.01 |
0.00544 |
0.000995 |
0.003490 |
0.00739 |
| 0.8 |
0.9320 |
6.31 |
0.00544 |
0.001020 |
0.003430 |
0.00745 |
| 0.9 |
0.9090 |
7.94 |
0.00544 |
0.001030 |
0.003410 |
0.00747 |
| 1.0 |
0.9000 |
10.00 |
0.00544 |
0.001040 |
0.003390 |
0.00748 |
| 1.1 |
0.8910 |
12.60 |
0.00531 |
0.001020 |
0.003320 |
0.00731 |
| 1.2 |
0.8790 |
15.80 |
0.00526 |
0.001010 |
0.003280 |
0.00725 |
| 1.3 |
0.8530 |
20.00 |
0.00526 |
0.001020 |
0.003260 |
0.00727 |
| 1.4 |
0.8270 |
25.10 |
0.00526 |
0.001060 |
0.003190 |
0.00734 |
| 1.5 |
0.7790 |
31.60 |
0.00526 |
0.001090 |
0.003130 |
0.00740 |
| 1.6 |
0.7450 |
39.80 |
0.00497 |
0.001070 |
0.002870 |
0.00707 |
| 1.7 |
0.7010 |
50.10 |
0.00488 |
0.001080 |
0.002760 |
0.00701 |
| 1.8 |
0.6550 |
63.10 |
0.00488 |
0.001130 |
0.002670 |
0.00710 |
| 1.9 |
0.6150 |
79.40 |
0.00488 |
0.001160 |
0.002610 |
0.00715 |
| 2.0 |
0.5360 |
100.00 |
0.00488 |
0.001260 |
0.002400 |
0.00736 |
| 2.1 |
0.4630 |
126.00 |
0.00488 |
0.001400 |
0.002150 |
0.00762 |
| 2.2 |
0.3790 |
158.00 |
0.00488 |
0.001520 |
0.001910 |
0.00785 |
| 2.3 |
0.3270 |
200.00 |
0.00439 |
0.001510 |
0.001430 |
0.00735 |
| 2.4 |
0.2760 |
251.00 |
0.00439 |
0.001790 |
0.000871 |
0.00791 |
| 2.5 |
0.2130 |
316.00 |
0.00439 |
0.002160 |
0.000153 |
0.00862 |
| 2.6 |
0.1640 |
398.00 |
0.00439 |
0.002530 |
-0.000568 |
0.00935 |
| 2.7 |
0.1200 |
501.00 |
0.00439 |
0.003680 |
-0.002820 |
0.01160 |
| 2.8 |
0.1060 |
631.00 |
0.00439 |
0.002920 |
-0.001330 |
0.01010 |
| 2.9 |
0.0781 |
794.00 |
0.00439 |
0.004290 |
-0.004020 |
0.01280 |
| 3.0 |
0.0658 |
1000.00 |
0.00439 |
0.003860 |
-0.003180 |
0.01200 |
| 3.1 |
0.0512 |
1260.00 |
0.00439 |
0.005710 |
-0.006800 |
0.01560 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9690 |
0.00537 |
0.000984 |
0.003440 |
0.00730 |
| 0.2 |
1.58 |
0.9690 |
0.00537 |
0.000984 |
0.003440 |
0.00730 |
| 0.3 |
2.00 |
0.9690 |
0.00537 |
0.000984 |
0.003440 |
0.00730 |
| 0.4 |
2.51 |
0.9690 |
0.00537 |
0.000984 |
0.003440 |
0.00730 |
| 0.5 |
3.16 |
0.9680 |
0.00538 |
0.000985 |
0.003440 |
0.00731 |
| 0.6 |
3.98 |
0.9630 |
0.00540 |
0.000989 |
0.003460 |
0.00733 |
| 0.7 |
5.01 |
0.9570 |
0.00542 |
0.000995 |
0.003470 |
0.00737 |
| 0.8 |
6.31 |
0.9320 |
0.00558 |
0.001020 |
0.003570 |
0.00758 |
| 0.9 |
7.94 |
0.9090 |
0.00555 |
0.001030 |
0.003520 |
0.00758 |
| 1.0 |
10.00 |
0.9000 |
0.00560 |
0.001040 |
0.003550 |
0.00764 |
| 1.1 |
12.60 |
0.8910 |
0.00531 |
0.001020 |
0.003320 |
0.00731 |
| 1.2 |
15.80 |
0.8790 |
0.00521 |
0.001010 |
0.003230 |
0.00719 |
| 1.3 |
20.00 |
0.8530 |
0.00519 |
0.001020 |
0.003180 |
0.00720 |
| 1.4 |
25.10 |
0.8270 |
0.00535 |
0.001060 |
0.003280 |
0.00743 |
| 1.5 |
31.60 |
0.7790 |
0.00531 |
0.001090 |
0.003170 |
0.00744 |
| 1.6 |
39.80 |
0.7450 |
0.00497 |
0.001070 |
0.002870 |
0.00707 |
| 1.7 |
50.10 |
0.7010 |
0.00474 |
0.001080 |
0.002610 |
0.00686 |
| 1.8 |
63.10 |
0.6550 |
0.00484 |
0.001130 |
0.002620 |
0.00705 |
| 1.9 |
79.40 |
0.6150 |
0.00474 |
0.001160 |
0.002460 |
0.00701 |
| 2.0 |
100.00 |
0.5360 |
0.00488 |
0.001260 |
0.002410 |
0.00736 |
| 2.1 |
126.00 |
0.4630 |
0.00520 |
0.001400 |
0.002470 |
0.00794 |
| 2.2 |
158.00 |
0.3790 |
0.00496 |
0.001520 |
0.001990 |
0.00794 |
| 2.3 |
200.00 |
0.3270 |
0.00437 |
0.001510 |
0.001420 |
0.00733 |
| 2.4 |
251.00 |
0.2760 |
0.00481 |
0.001790 |
0.001290 |
0.00832 |
| 2.5 |
316.00 |
0.2130 |
0.00539 |
0.002160 |
0.001150 |
0.00962 |
| 2.6 |
398.00 |
0.1640 |
0.00597 |
0.002530 |
0.001010 |
0.01090 |
| 2.7 |
501.00 |
0.1200 |
0.00827 |
0.003680 |
0.001060 |
0.01550 |
| 2.8 |
631.00 |
0.1060 |
0.00518 |
0.002920 |
-0.000537 |
0.01090 |
| 2.9 |
794.00 |
0.0781 |
0.00653 |
0.004290 |
-0.001870 |
0.01490 |
| 3.0 |
1000.00 |
0.0658 |
0.00518 |
0.003860 |
-0.002380 |
0.01280 |
| 3.1 |
1260.00 |
0.0512 |
0.00655 |
0.005710 |
-0.004640 |
0.01770 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.228 |
0.164 |
-0.09420 |
0.549 |
| 0.1 |
0.9690 |
1.26 |
0.294 |
0.163 |
-0.02620 |
0.614 |
| 0.2 |
0.9690 |
1.58 |
0.294 |
0.163 |
-0.02620 |
0.614 |
| 0.3 |
0.9690 |
2.00 |
0.294 |
0.163 |
-0.02620 |
0.614 |
| 0.4 |
0.9690 |
2.51 |
0.294 |
0.163 |
-0.02620 |
0.614 |
| 0.5 |
0.9680 |
3.16 |
0.294 |
0.164 |
-0.02660 |
0.614 |
| 0.6 |
0.9630 |
3.98 |
0.294 |
0.164 |
-0.02740 |
0.615 |
| 0.7 |
0.9570 |
5.01 |
0.294 |
0.164 |
-0.02840 |
0.616 |
| 0.8 |
0.9320 |
6.31 |
0.294 |
0.168 |
-0.03460 |
0.622 |
| 0.9 |
0.9090 |
7.94 |
0.294 |
0.169 |
-0.03650 |
0.624 |
| 1.0 |
0.9000 |
10.00 |
0.294 |
0.170 |
-0.03840 |
0.626 |
| 1.1 |
0.8910 |
12.60 |
0.310 |
0.165 |
-0.01390 |
0.634 |
| 1.2 |
0.8790 |
15.80 |
0.316 |
0.164 |
-0.00540 |
0.638 |
| 1.3 |
0.8530 |
20.00 |
0.316 |
0.166 |
-0.00799 |
0.641 |
| 1.4 |
0.8270 |
25.10 |
0.316 |
0.169 |
-0.01510 |
0.648 |
| 1.5 |
0.7790 |
31.60 |
0.316 |
0.172 |
-0.02120 |
0.654 |
| 1.6 |
0.7450 |
39.80 |
0.355 |
0.167 |
0.02660 |
0.683 |
| 1.7 |
0.7010 |
50.10 |
0.366 |
0.168 |
0.03710 |
0.695 |
| 1.8 |
0.6550 |
63.10 |
0.366 |
0.173 |
0.02720 |
0.705 |
| 1.9 |
0.6150 |
79.40 |
0.366 |
0.176 |
0.02080 |
0.711 |
| 2.0 |
0.5360 |
100.00 |
0.366 |
0.188 |
-0.00210 |
0.734 |
| 2.1 |
0.4630 |
126.00 |
0.366 |
0.203 |
-0.03180 |
0.764 |
| 2.2 |
0.3790 |
158.00 |
0.366 |
0.217 |
-0.05930 |
0.791 |
| 2.3 |
0.3270 |
200.00 |
0.430 |
0.213 |
0.01360 |
0.847 |
| 2.4 |
0.2760 |
251.00 |
0.430 |
0.247 |
-0.05420 |
0.914 |
| 2.5 |
0.2130 |
316.00 |
0.430 |
0.292 |
-0.14300 |
1.000 |
| 2.6 |
0.1640 |
398.00 |
0.430 |
0.339 |
-0.23300 |
1.090 |
| 2.7 |
0.1200 |
501.00 |
0.430 |
0.485 |
-0.52000 |
1.380 |
| 2.8 |
0.1060 |
631.00 |
0.430 |
0.387 |
-0.32900 |
1.190 |
| 2.9 |
0.0781 |
794.00 |
0.430 |
0.563 |
-0.67300 |
1.530 |
| 3.0 |
0.0658 |
1000.00 |
0.430 |
0.508 |
-0.56600 |
1.430 |
| 3.1 |
0.0512 |
1260.00 |
0.430 |
0.746 |
-1.03000 |
1.890 |
IgG3_gp70BCaseA2V1V2mut3
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00595 |
0.000929 |
0.004130 |
0.00777 |
| 0.1 |
0.9830 |
1.26 |
0.00584 |
0.001010 |
0.003850 |
0.00783 |
| 0.2 |
0.9830 |
1.58 |
0.00584 |
0.001010 |
0.003850 |
0.00783 |
| 0.3 |
0.9830 |
2.00 |
0.00584 |
0.001010 |
0.003850 |
0.00783 |
| 0.4 |
0.9830 |
2.51 |
0.00584 |
0.001010 |
0.003850 |
0.00783 |
| 0.5 |
0.9820 |
3.16 |
0.00584 |
0.001020 |
0.003850 |
0.00783 |
| 0.6 |
0.9820 |
3.98 |
0.00584 |
0.001020 |
0.003850 |
0.00783 |
| 0.7 |
0.9770 |
5.01 |
0.00584 |
0.001020 |
0.003840 |
0.00784 |
| 0.8 |
0.9770 |
6.31 |
0.00584 |
0.001020 |
0.003840 |
0.00784 |
| 0.9 |
0.9730 |
7.94 |
0.00584 |
0.001030 |
0.003830 |
0.00785 |
| 1.0 |
0.9730 |
10.00 |
0.00584 |
0.001030 |
0.003830 |
0.00785 |
| 1.1 |
0.9660 |
12.60 |
0.00584 |
0.001030 |
0.003820 |
0.00786 |
| 1.2 |
0.9660 |
15.80 |
0.00584 |
0.001030 |
0.003820 |
0.00786 |
| 1.3 |
0.9660 |
20.00 |
0.00584 |
0.001030 |
0.003820 |
0.00786 |
| 1.4 |
0.9560 |
25.10 |
0.00584 |
0.001040 |
0.003800 |
0.00788 |
| 1.5 |
0.9510 |
31.60 |
0.00584 |
0.001050 |
0.003790 |
0.00789 |
| 1.6 |
0.9470 |
39.80 |
0.00584 |
0.001020 |
0.003840 |
0.00784 |
| 1.7 |
0.9470 |
50.10 |
0.00584 |
0.001020 |
0.003840 |
0.00784 |
| 1.8 |
0.9360 |
63.10 |
0.00584 |
0.001030 |
0.003810 |
0.00787 |
| 1.9 |
0.9240 |
79.40 |
0.00584 |
0.001030 |
0.003820 |
0.00786 |
| 2.0 |
0.9100 |
100.00 |
0.00584 |
0.001030 |
0.003830 |
0.00786 |
| 2.1 |
0.8860 |
126.00 |
0.00584 |
0.001060 |
0.003760 |
0.00792 |
| 2.2 |
0.8660 |
158.00 |
0.00584 |
0.001070 |
0.003750 |
0.00794 |
| 2.3 |
0.8400 |
200.00 |
0.00584 |
0.001080 |
0.003720 |
0.00796 |
| 2.4 |
0.8310 |
251.00 |
0.00584 |
0.001070 |
0.003740 |
0.00795 |
| 2.5 |
0.8130 |
316.00 |
0.00584 |
0.001060 |
0.003770 |
0.00792 |
| 2.6 |
0.7360 |
398.00 |
0.00584 |
0.001090 |
0.003710 |
0.00797 |
| 2.7 |
0.6780 |
501.00 |
0.00584 |
0.001190 |
0.003510 |
0.00817 |
| 2.8 |
0.6200 |
631.00 |
0.00584 |
0.001290 |
0.003320 |
0.00836 |
| 2.9 |
0.5480 |
794.00 |
0.00584 |
0.001470 |
0.002970 |
0.00872 |
| 3.0 |
0.4750 |
1000.00 |
0.00584 |
0.001580 |
0.002740 |
0.00894 |
| 3.1 |
0.4220 |
1260.00 |
0.00584 |
0.001710 |
0.002500 |
0.00918 |
| 3.2 |
0.3250 |
1580.00 |
0.00584 |
0.002010 |
0.001910 |
0.00977 |
| 3.3 |
0.2650 |
2000.00 |
0.00584 |
0.002200 |
0.001530 |
0.01020 |
| 3.4 |
0.2370 |
2510.00 |
0.00584 |
0.002530 |
0.000891 |
0.01080 |
| 3.5 |
0.1710 |
3160.00 |
0.00584 |
0.003350 |
-0.000720 |
0.01240 |
| 3.6 |
0.1350 |
3980.00 |
0.00584 |
0.003950 |
-0.001910 |
0.01360 |
| 3.7 |
0.0950 |
5010.00 |
0.00584 |
0.004830 |
-0.003620 |
0.01530 |
| 3.8 |
0.0745 |
6310.00 |
0.00584 |
0.005310 |
-0.004560 |
0.01620 |
| 3.9 |
0.0654 |
7940.00 |
0.00584 |
0.005130 |
-0.004210 |
0.01590 |
| 4.0 |
0.0451 |
10000.00 |
0.00584 |
0.007840 |
-0.009520 |
0.02120 |
| 4.1 |
0.0451 |
12600.00 |
0.00584 |
0.007840 |
-0.009520 |
0.02120 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00595 |
0.000929 |
0.003920 |
0.00797 |
| 0.1 |
1.26 |
0.9830 |
0.00573 |
0.001010 |
0.003740 |
0.00771 |
| 0.2 |
1.58 |
0.9830 |
0.00573 |
0.001010 |
0.003740 |
0.00771 |
| 0.3 |
2.00 |
0.9830 |
0.00573 |
0.001010 |
0.003740 |
0.00771 |
| 0.4 |
2.51 |
0.9830 |
0.00573 |
0.001010 |
0.003740 |
0.00771 |
| 0.5 |
3.16 |
0.9820 |
0.00573 |
0.001020 |
0.003740 |
0.00772 |
| 0.6 |
3.98 |
0.9820 |
0.00573 |
0.001020 |
0.003740 |
0.00772 |
| 0.7 |
5.01 |
0.9770 |
0.00576 |
0.001020 |
0.003760 |
0.00776 |
| 0.8 |
6.31 |
0.9770 |
0.00576 |
0.001020 |
0.003760 |
0.00776 |
| 0.9 |
7.94 |
0.9730 |
0.00578 |
0.001030 |
0.003770 |
0.00779 |
| 1.0 |
10.00 |
0.9730 |
0.00578 |
0.001030 |
0.003770 |
0.00779 |
| 1.1 |
12.60 |
0.9660 |
0.00581 |
0.001030 |
0.003790 |
0.00784 |
| 1.2 |
15.80 |
0.9660 |
0.00581 |
0.001030 |
0.003790 |
0.00784 |
| 1.3 |
20.00 |
0.9660 |
0.00581 |
0.001030 |
0.003790 |
0.00784 |
| 1.4 |
25.10 |
0.9560 |
0.00587 |
0.001040 |
0.003830 |
0.00791 |
| 1.5 |
31.60 |
0.9510 |
0.00590 |
0.001050 |
0.003840 |
0.00795 |
| 1.6 |
39.80 |
0.9470 |
0.00562 |
0.001020 |
0.003620 |
0.00762 |
| 1.7 |
50.10 |
0.9470 |
0.00562 |
0.001020 |
0.003620 |
0.00762 |
| 1.8 |
63.10 |
0.9360 |
0.00569 |
0.001030 |
0.003670 |
0.00772 |
| 1.9 |
79.40 |
0.9240 |
0.00560 |
0.001030 |
0.003580 |
0.00761 |
| 2.0 |
100.00 |
0.9100 |
0.00552 |
0.001030 |
0.003500 |
0.00754 |
| 2.1 |
126.00 |
0.8860 |
0.00568 |
0.001060 |
0.003600 |
0.00776 |
| 2.2 |
158.00 |
0.8660 |
0.00564 |
0.001070 |
0.003540 |
0.00773 |
| 2.3 |
200.00 |
0.8400 |
0.00563 |
0.001080 |
0.003500 |
0.00775 |
| 2.4 |
251.00 |
0.8310 |
0.00550 |
0.001070 |
0.003400 |
0.00761 |
| 2.5 |
316.00 |
0.8130 |
0.00527 |
0.001060 |
0.003190 |
0.00734 |
| 2.6 |
398.00 |
0.7360 |
0.00503 |
0.001090 |
0.002900 |
0.00716 |
| 2.7 |
501.00 |
0.6780 |
0.00548 |
0.001190 |
0.003150 |
0.00781 |
| 2.8 |
631.00 |
0.6200 |
0.00579 |
0.001290 |
0.003270 |
0.00831 |
| 2.9 |
794.00 |
0.5480 |
0.00655 |
0.001470 |
0.003670 |
0.00942 |
| 3.0 |
1000.00 |
0.4750 |
0.00648 |
0.001580 |
0.003380 |
0.00959 |
| 3.1 |
1260.00 |
0.4220 |
0.00648 |
0.001710 |
0.003140 |
0.00982 |
| 3.2 |
1580.00 |
0.3250 |
0.00669 |
0.002010 |
0.002750 |
0.01060 |
| 3.3 |
2000.00 |
0.2650 |
0.00673 |
0.002200 |
0.002420 |
0.01100 |
| 3.4 |
2510.00 |
0.2370 |
0.00727 |
0.002530 |
0.002320 |
0.01220 |
| 3.5 |
3160.00 |
0.1710 |
0.00913 |
0.003350 |
0.002570 |
0.01570 |
| 3.6 |
3980.00 |
0.1350 |
0.00953 |
0.003950 |
0.001780 |
0.01730 |
| 3.7 |
5010.00 |
0.0950 |
0.00992 |
0.004830 |
0.000462 |
0.01940 |
| 3.8 |
6310.00 |
0.0745 |
0.01000 |
0.005310 |
-0.000403 |
0.02040 |
| 3.9 |
7940.00 |
0.0654 |
0.00763 |
0.005130 |
-0.002420 |
0.01770 |
| 4.0 |
10000.00 |
0.0451 |
0.01110 |
0.007840 |
-0.004290 |
0.02640 |
| 4.1 |
12600.00 |
0.0451 |
0.01110 |
0.007840 |
-0.004290 |
0.02640 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.228 |
0.164 |
-0.0942 |
0.549 |
| 0.1 |
0.9830 |
1.26 |
0.241 |
0.171 |
-0.0941 |
0.577 |
| 0.2 |
0.9830 |
1.58 |
0.241 |
0.171 |
-0.0941 |
0.577 |
| 0.3 |
0.9830 |
2.00 |
0.241 |
0.171 |
-0.0941 |
0.577 |
| 0.4 |
0.9830 |
2.51 |
0.241 |
0.171 |
-0.0941 |
0.577 |
| 0.5 |
0.9820 |
3.16 |
0.241 |
0.171 |
-0.0943 |
0.577 |
| 0.6 |
0.9820 |
3.98 |
0.241 |
0.171 |
-0.0943 |
0.577 |
| 0.7 |
0.9770 |
5.01 |
0.241 |
0.172 |
-0.0953 |
0.578 |
| 0.8 |
0.9770 |
6.31 |
0.241 |
0.172 |
-0.0953 |
0.578 |
| 0.9 |
0.9730 |
7.94 |
0.241 |
0.172 |
-0.0963 |
0.579 |
| 1.0 |
0.9730 |
10.00 |
0.241 |
0.172 |
-0.0963 |
0.579 |
| 1.1 |
0.9660 |
12.60 |
0.241 |
0.173 |
-0.0976 |
0.580 |
| 1.2 |
0.9660 |
15.80 |
0.241 |
0.173 |
-0.0976 |
0.580 |
| 1.3 |
0.9660 |
20.00 |
0.241 |
0.173 |
-0.0976 |
0.580 |
| 1.4 |
0.9560 |
25.10 |
0.241 |
0.174 |
-0.0994 |
0.582 |
| 1.5 |
0.9510 |
31.60 |
0.241 |
0.174 |
-0.1000 |
0.583 |
| 1.6 |
0.9470 |
39.80 |
0.241 |
0.172 |
-0.0953 |
0.578 |
| 1.7 |
0.9470 |
50.10 |
0.241 |
0.172 |
-0.0953 |
0.578 |
| 1.8 |
0.9360 |
63.10 |
0.241 |
0.173 |
-0.0981 |
0.581 |
| 1.9 |
0.9240 |
79.40 |
0.241 |
0.173 |
-0.0970 |
0.580 |
| 2.0 |
0.9100 |
100.00 |
0.241 |
0.173 |
-0.0969 |
0.580 |
| 2.1 |
0.8860 |
126.00 |
0.241 |
0.176 |
-0.1030 |
0.586 |
| 2.2 |
0.8660 |
158.00 |
0.241 |
0.177 |
-0.1050 |
0.588 |
| 2.3 |
0.8400 |
200.00 |
0.241 |
0.178 |
-0.1080 |
0.591 |
| 2.4 |
0.8310 |
251.00 |
0.241 |
0.177 |
-0.1060 |
0.589 |
| 2.5 |
0.8130 |
316.00 |
0.241 |
0.176 |
-0.1030 |
0.586 |
| 2.6 |
0.7360 |
398.00 |
0.241 |
0.179 |
-0.1090 |
0.591 |
| 2.7 |
0.6780 |
501.00 |
0.241 |
0.189 |
-0.1290 |
0.612 |
| 2.8 |
0.6200 |
631.00 |
0.241 |
0.200 |
-0.1500 |
0.633 |
| 2.9 |
0.5480 |
794.00 |
0.241 |
0.220 |
-0.1890 |
0.672 |
| 3.0 |
0.4750 |
1000.00 |
0.241 |
0.233 |
-0.2150 |
0.698 |
| 3.1 |
0.4220 |
1260.00 |
0.241 |
0.247 |
-0.2430 |
0.725 |
| 3.2 |
0.3250 |
1580.00 |
0.241 |
0.283 |
-0.3120 |
0.795 |
| 3.3 |
0.2650 |
2000.00 |
0.241 |
0.306 |
-0.3580 |
0.841 |
| 3.4 |
0.2370 |
2510.00 |
0.241 |
0.346 |
-0.4360 |
0.919 |
| 3.5 |
0.1710 |
3160.00 |
0.241 |
0.448 |
-0.6370 |
1.120 |
| 3.6 |
0.1350 |
3980.00 |
0.241 |
0.525 |
-0.7870 |
1.270 |
| 3.7 |
0.0950 |
5010.00 |
0.241 |
0.636 |
-1.0100 |
1.490 |
| 3.8 |
0.0745 |
6310.00 |
0.241 |
0.698 |
-1.1300 |
1.610 |
| 3.9 |
0.0654 |
7940.00 |
0.241 |
0.675 |
-1.0800 |
1.560 |
| 4.0 |
0.0451 |
10000.00 |
0.241 |
1.020 |
-1.7600 |
2.250 |
| 4.1 |
0.0451 |
12600.00 |
0.241 |
1.020 |
-1.7600 |
2.250 |
Combined HVTN 705 + RV144 analyses (24 month)
- Adjustment covariates: Region (RV144, South Africa,
Outside South Africa), age above or below 26
- Event time variable: HIVwk26fu (RV144) and
Ttilde.D210 (HVTN 705)
- Event type variable: HIVwk26 (RV144) and Delta.D210
(HVTN 705)
- Weight variable: sample_weight (RV144) and wt.D210
(HVTN 705)
- Reference timepoint: 459 days (earliest between
RV144 and HVTN 705)
- Filter for HVTN 705: !is.na(Ttilde.D210)
- All learners: GLM
IgG V1V2 B.CaseA-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00871 |
0.00104 |
6.67e-03 |
0.01070 |
| 0.1 |
0.9830 |
1.26 |
0.00871 |
0.00122 |
6.32e-03 |
0.01110 |
| 0.2 |
0.9830 |
1.58 |
0.00871 |
0.00122 |
6.32e-03 |
0.01110 |
| 0.3 |
0.9830 |
2.00 |
0.00871 |
0.00122 |
6.32e-03 |
0.01110 |
| 0.4 |
0.9820 |
2.51 |
0.00871 |
0.00122 |
6.32e-03 |
0.01110 |
| 0.5 |
0.9820 |
3.16 |
0.00871 |
0.00122 |
6.32e-03 |
0.01110 |
| 0.6 |
0.9820 |
3.98 |
0.00871 |
0.00122 |
6.32e-03 |
0.01110 |
| 0.7 |
0.9820 |
5.01 |
0.00871 |
0.00122 |
6.32e-03 |
0.01110 |
| 0.8 |
0.9800 |
6.31 |
0.00871 |
0.00122 |
6.32e-03 |
0.01110 |
| 0.9 |
0.9800 |
7.94 |
0.00871 |
0.00122 |
6.32e-03 |
0.01110 |
| 1.0 |
0.9780 |
10.00 |
0.00871 |
0.00122 |
6.32e-03 |
0.01110 |
| 1.1 |
0.9760 |
12.60 |
0.00871 |
0.00122 |
6.31e-03 |
0.01110 |
| 1.2 |
0.9690 |
15.80 |
0.00871 |
0.00124 |
6.28e-03 |
0.01110 |
| 1.3 |
0.9620 |
20.00 |
0.00871 |
0.00124 |
6.27e-03 |
0.01110 |
| 1.4 |
0.9600 |
25.10 |
0.00871 |
0.00123 |
6.29e-03 |
0.01110 |
| 1.5 |
0.9540 |
31.60 |
0.00871 |
0.00125 |
6.26e-03 |
0.01120 |
| 1.6 |
0.9450 |
39.80 |
0.00871 |
0.00126 |
6.24e-03 |
0.01120 |
| 1.7 |
0.9380 |
50.10 |
0.00855 |
0.00125 |
6.09e-03 |
0.01100 |
| 1.8 |
0.9170 |
63.10 |
0.00831 |
0.00125 |
5.86e-03 |
0.01070 |
| 1.9 |
0.9150 |
79.40 |
0.00805 |
0.00122 |
5.65e-03 |
0.01050 |
| 2.0 |
0.9020 |
100.00 |
0.00805 |
0.00124 |
5.61e-03 |
0.01050 |
| 2.1 |
0.8880 |
126.00 |
0.00792 |
0.00123 |
5.51e-03 |
0.01030 |
| 2.2 |
0.8650 |
158.00 |
0.00792 |
0.00125 |
5.47e-03 |
0.01040 |
| 2.3 |
0.8160 |
200.00 |
0.00792 |
0.00125 |
5.47e-03 |
0.01040 |
| 2.4 |
0.7780 |
251.00 |
0.00792 |
0.00129 |
5.39e-03 |
0.01050 |
| 2.5 |
0.7250 |
316.00 |
0.00792 |
0.00131 |
5.35e-03 |
0.01050 |
| 2.6 |
0.6690 |
398.00 |
0.00792 |
0.00134 |
5.30e-03 |
0.01060 |
| 2.7 |
0.6130 |
501.00 |
0.00792 |
0.00145 |
5.08e-03 |
0.01080 |
| 2.8 |
0.5240 |
631.00 |
0.00792 |
0.00156 |
4.87e-03 |
0.01100 |
| 2.9 |
0.4900 |
794.00 |
0.00792 |
0.00157 |
4.84e-03 |
0.01100 |
| 3.0 |
0.4190 |
1000.00 |
0.00730 |
0.00155 |
4.26e-03 |
0.01030 |
| 3.1 |
0.3610 |
1260.00 |
0.00685 |
0.00160 |
3.72e-03 |
0.00999 |
| 3.2 |
0.2960 |
1580.00 |
0.00676 |
0.00168 |
3.47e-03 |
0.01000 |
| 3.3 |
0.2260 |
2000.00 |
0.00676 |
0.00198 |
2.88e-03 |
0.01060 |
| 3.4 |
0.1870 |
2510.00 |
0.00668 |
0.00217 |
2.42e-03 |
0.01090 |
| 3.5 |
0.1560 |
3160.00 |
0.00668 |
0.00209 |
2.57e-03 |
0.01080 |
| 3.6 |
0.1250 |
3980.00 |
0.00668 |
0.00298 |
8.43e-04 |
0.01250 |
| 3.7 |
0.0969 |
5010.00 |
0.00668 |
0.00325 |
3.00e-04 |
0.01310 |
| 3.8 |
0.0671 |
6310.00 |
0.00481 |
0.00180 |
1.29e-03 |
0.00833 |
| 3.9 |
0.0547 |
7940.00 |
0.00481 |
0.00184 |
1.20e-03 |
0.00842 |
| 4.0 |
0.0447 |
10000.00 |
0.00481 |
0.00247 |
-3.97e-05 |
0.00966 |
| 4.1 |
0.0379 |
12600.00 |
0.00481 |
0.00303 |
-1.13e-03 |
0.01080 |
| 4.2 |
0.0306 |
15800.00 |
0.00481 |
0.00323 |
-1.52e-03 |
0.01110 |
| 4.3 |
0.0225 |
20000.00 |
0.00409 |
0.00272 |
-1.25e-03 |
0.00943 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00870 |
0.00104 |
0.006720 |
0.01150 |
| 0.1 |
1.26 |
0.9830 |
0.00867 |
0.00122 |
0.006280 |
0.01110 |
| 0.2 |
1.58 |
0.9830 |
0.00867 |
0.00122 |
0.006280 |
0.01110 |
| 0.3 |
2.00 |
0.9830 |
0.00867 |
0.00122 |
0.006280 |
0.01110 |
| 0.4 |
2.51 |
0.9820 |
0.00868 |
0.00122 |
0.006290 |
0.01110 |
| 0.5 |
3.16 |
0.9820 |
0.00868 |
0.00122 |
0.006290 |
0.01110 |
| 0.6 |
3.98 |
0.9820 |
0.00868 |
0.00122 |
0.006290 |
0.01110 |
| 0.7 |
5.01 |
0.9820 |
0.00868 |
0.00122 |
0.006290 |
0.01110 |
| 0.8 |
6.31 |
0.9800 |
0.00868 |
0.00122 |
0.006290 |
0.01110 |
| 0.9 |
7.94 |
0.9800 |
0.00868 |
0.00122 |
0.006290 |
0.01110 |
| 1.0 |
10.00 |
0.9780 |
0.00869 |
0.00122 |
0.006300 |
0.01110 |
| 1.1 |
12.60 |
0.9760 |
0.00871 |
0.00122 |
0.006310 |
0.01110 |
| 1.2 |
15.80 |
0.9690 |
0.00881 |
0.00124 |
0.006380 |
0.01120 |
| 1.3 |
20.00 |
0.9620 |
0.00883 |
0.00124 |
0.006400 |
0.01130 |
| 1.4 |
25.10 |
0.9600 |
0.00871 |
0.00123 |
0.006290 |
0.01110 |
| 1.5 |
31.60 |
0.9540 |
0.00879 |
0.00125 |
0.006340 |
0.01120 |
| 1.6 |
39.80 |
0.9450 |
0.00877 |
0.00126 |
0.006300 |
0.01120 |
| 1.7 |
50.10 |
0.9380 |
0.00855 |
0.00125 |
0.006090 |
0.01100 |
| 1.8 |
63.10 |
0.9170 |
0.00831 |
0.00125 |
0.005860 |
0.01070 |
| 1.9 |
79.40 |
0.9150 |
0.00804 |
0.00122 |
0.005640 |
0.01040 |
| 2.0 |
100.00 |
0.9020 |
0.00806 |
0.00124 |
0.005620 |
0.01050 |
| 2.1 |
126.00 |
0.8880 |
0.00786 |
0.00123 |
0.005450 |
0.01030 |
| 2.2 |
158.00 |
0.8650 |
0.00790 |
0.00125 |
0.005450 |
0.01030 |
| 2.3 |
200.00 |
0.8160 |
0.00772 |
0.00125 |
0.005270 |
0.01020 |
| 2.4 |
251.00 |
0.7780 |
0.00779 |
0.00129 |
0.005260 |
0.01030 |
| 2.5 |
316.00 |
0.7250 |
0.00779 |
0.00131 |
0.005210 |
0.01040 |
| 2.6 |
398.00 |
0.6690 |
0.00759 |
0.00134 |
0.004970 |
0.01020 |
| 2.7 |
501.00 |
0.6130 |
0.00811 |
0.00145 |
0.005260 |
0.01100 |
| 2.8 |
631.00 |
0.5240 |
0.00845 |
0.00156 |
0.005400 |
0.01150 |
| 2.9 |
794.00 |
0.4900 |
0.00821 |
0.00157 |
0.005120 |
0.01130 |
| 3.0 |
1000.00 |
0.4190 |
0.00730 |
0.00155 |
0.004260 |
0.01030 |
| 3.1 |
1260.00 |
0.3610 |
0.00685 |
0.00160 |
0.003720 |
0.00999 |
| 3.2 |
1580.00 |
0.2960 |
0.00669 |
0.00168 |
0.003400 |
0.00998 |
| 3.3 |
2000.00 |
0.2260 |
0.00684 |
0.00198 |
0.002960 |
0.01070 |
| 3.4 |
2510.00 |
0.1870 |
0.00661 |
0.00217 |
0.002350 |
0.01090 |
| 3.5 |
3160.00 |
0.1560 |
0.00602 |
0.00209 |
0.001910 |
0.01010 |
| 3.6 |
3980.00 |
0.1250 |
0.00693 |
0.00298 |
0.001090 |
0.01280 |
| 3.7 |
5010.00 |
0.0969 |
0.00725 |
0.00325 |
0.000876 |
0.01360 |
| 3.8 |
6310.00 |
0.0671 |
0.00429 |
0.00180 |
0.000771 |
0.00781 |
| 3.9 |
7940.00 |
0.0547 |
0.00381 |
0.00184 |
0.000201 |
0.00742 |
| 4.0 |
10000.00 |
0.0447 |
0.00513 |
0.00247 |
0.000282 |
0.00998 |
| 4.1 |
12600.00 |
0.0379 |
0.00553 |
0.00303 |
-0.000410 |
0.01150 |
| 4.2 |
15800.00 |
0.0306 |
0.00528 |
0.00323 |
-0.001040 |
0.01160 |
| 4.3 |
20000.00 |
0.0225 |
0.00409 |
0.00272 |
-0.001250 |
0.00943 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.289 |
0.113 |
0.0671 |
0.510 |
| 0.1 |
0.9830 |
1.26 |
0.289 |
0.124 |
0.0447 |
0.532 |
| 0.2 |
0.9830 |
1.58 |
0.289 |
0.124 |
0.0447 |
0.532 |
| 0.3 |
0.9830 |
2.00 |
0.289 |
0.124 |
0.0447 |
0.532 |
| 0.4 |
0.9820 |
2.51 |
0.289 |
0.124 |
0.0446 |
0.533 |
| 0.5 |
0.9820 |
3.16 |
0.289 |
0.124 |
0.0446 |
0.533 |
| 0.6 |
0.9820 |
3.98 |
0.289 |
0.124 |
0.0446 |
0.533 |
| 0.7 |
0.9820 |
5.01 |
0.289 |
0.124 |
0.0446 |
0.533 |
| 0.8 |
0.9800 |
6.31 |
0.289 |
0.125 |
0.0445 |
0.533 |
| 0.9 |
0.9800 |
7.94 |
0.289 |
0.125 |
0.0445 |
0.533 |
| 1.0 |
0.9780 |
10.00 |
0.289 |
0.125 |
0.0444 |
0.533 |
| 1.1 |
0.9760 |
12.60 |
0.289 |
0.125 |
0.0440 |
0.533 |
| 1.2 |
0.9690 |
15.80 |
0.289 |
0.126 |
0.0420 |
0.535 |
| 1.3 |
0.9620 |
20.00 |
0.289 |
0.126 |
0.0415 |
0.536 |
| 1.4 |
0.9600 |
25.10 |
0.289 |
0.125 |
0.0427 |
0.535 |
| 1.5 |
0.9540 |
31.60 |
0.289 |
0.126 |
0.0407 |
0.536 |
| 1.6 |
0.9450 |
39.80 |
0.289 |
0.127 |
0.0397 |
0.538 |
| 1.7 |
0.9380 |
50.10 |
0.302 |
0.126 |
0.0553 |
0.549 |
| 1.8 |
0.9170 |
63.10 |
0.322 |
0.124 |
0.0782 |
0.565 |
| 1.9 |
0.9150 |
79.40 |
0.343 |
0.122 |
0.1040 |
0.581 |
| 2.0 |
0.9020 |
100.00 |
0.343 |
0.123 |
0.1020 |
0.583 |
| 2.1 |
0.8880 |
126.00 |
0.353 |
0.121 |
0.1150 |
0.591 |
| 2.2 |
0.8650 |
158.00 |
0.353 |
0.123 |
0.1130 |
0.593 |
| 2.3 |
0.8160 |
200.00 |
0.353 |
0.123 |
0.1120 |
0.594 |
| 2.4 |
0.7780 |
251.00 |
0.353 |
0.125 |
0.1070 |
0.599 |
| 2.5 |
0.7250 |
316.00 |
0.353 |
0.127 |
0.1040 |
0.602 |
| 2.6 |
0.6690 |
398.00 |
0.353 |
0.129 |
0.1000 |
0.605 |
| 2.7 |
0.6130 |
501.00 |
0.353 |
0.137 |
0.0849 |
0.621 |
| 2.8 |
0.5240 |
631.00 |
0.353 |
0.144 |
0.0698 |
0.636 |
| 2.9 |
0.4900 |
794.00 |
0.353 |
0.145 |
0.0679 |
0.638 |
| 3.0 |
0.4190 |
1000.00 |
0.404 |
0.141 |
0.1270 |
0.681 |
| 3.1 |
0.3610 |
1260.00 |
0.440 |
0.143 |
0.1590 |
0.721 |
| 3.2 |
0.2960 |
1580.00 |
0.448 |
0.149 |
0.1560 |
0.740 |
| 3.3 |
0.2260 |
2000.00 |
0.448 |
0.172 |
0.1110 |
0.784 |
| 3.4 |
0.1870 |
2510.00 |
0.455 |
0.187 |
0.0888 |
0.820 |
| 3.5 |
0.1560 |
3160.00 |
0.455 |
0.180 |
0.1010 |
0.808 |
| 3.6 |
0.1250 |
3980.00 |
0.455 |
0.250 |
-0.0352 |
0.944 |
| 3.7 |
0.0969 |
5010.00 |
0.455 |
0.272 |
-0.0784 |
0.987 |
| 3.8 |
0.0671 |
6310.00 |
0.607 |
0.152 |
0.3090 |
0.906 |
| 3.9 |
0.0547 |
7940.00 |
0.607 |
0.156 |
0.3020 |
0.913 |
| 4.0 |
0.0447 |
10000.00 |
0.607 |
0.206 |
0.2030 |
1.010 |
| 4.1 |
0.0379 |
12600.00 |
0.607 |
0.251 |
0.1150 |
1.100 |
| 4.2 |
0.0306 |
15800.00 |
0.607 |
0.267 |
0.0844 |
1.130 |
| 4.3 |
0.0225 |
20000.00 |
0.666 |
0.225 |
0.2250 |
1.110 |
IgG V1V2 C.1086-gp70
Monotone

| 0.0 |
1.000 |
1.00 |
0.00909 |
0.00104 |
0.00705 |
0.0111 |
| 0.1 |
0.993 |
1.26 |
0.00909 |
0.00123 |
0.00668 |
0.0115 |
| 0.2 |
0.993 |
1.58 |
0.00909 |
0.00123 |
0.00668 |
0.0115 |
| 0.3 |
0.993 |
2.00 |
0.00909 |
0.00123 |
0.00668 |
0.0115 |
| 0.4 |
0.991 |
2.51 |
0.00909 |
0.00123 |
0.00668 |
0.0115 |
| 0.5 |
0.990 |
3.16 |
0.00909 |
0.00123 |
0.00668 |
0.0115 |
| 0.6 |
0.990 |
3.98 |
0.00909 |
0.00123 |
0.00668 |
0.0115 |
| 0.7 |
0.990 |
5.01 |
0.00903 |
0.00122 |
0.00664 |
0.0114 |
| 0.8 |
0.990 |
6.31 |
0.00903 |
0.00122 |
0.00664 |
0.0114 |
| 0.9 |
0.990 |
7.94 |
0.00903 |
0.00122 |
0.00664 |
0.0114 |
| 1.0 |
0.990 |
10.00 |
0.00903 |
0.00122 |
0.00664 |
0.0114 |
| 1.1 |
0.988 |
12.60 |
0.00900 |
0.00121 |
0.00663 |
0.0114 |
| 1.2 |
0.988 |
15.80 |
0.00900 |
0.00121 |
0.00663 |
0.0114 |
| 1.3 |
0.988 |
20.00 |
0.00900 |
0.00121 |
0.00663 |
0.0114 |
| 1.4 |
0.988 |
25.10 |
0.00900 |
0.00121 |
0.00662 |
0.0114 |
| 1.5 |
0.988 |
31.60 |
0.00900 |
0.00121 |
0.00662 |
0.0114 |
| 1.6 |
0.988 |
39.80 |
0.00900 |
0.00121 |
0.00662 |
0.0114 |
| 1.7 |
0.987 |
50.10 |
0.00900 |
0.00120 |
0.00664 |
0.0114 |
| 1.8 |
0.987 |
63.10 |
0.00900 |
0.00121 |
0.00663 |
0.0114 |
| 1.9 |
0.985 |
79.40 |
0.00900 |
0.00121 |
0.00663 |
0.0114 |
| 2.0 |
0.984 |
100.00 |
0.00900 |
0.00121 |
0.00662 |
0.0114 |
| 2.1 |
0.982 |
126.00 |
0.00900 |
0.00122 |
0.00661 |
0.0114 |
| 2.2 |
0.981 |
158.00 |
0.00900 |
0.00122 |
0.00661 |
0.0114 |
| 2.3 |
0.980 |
200.00 |
0.00900 |
0.00123 |
0.00659 |
0.0114 |
| 2.4 |
0.980 |
251.00 |
0.00900 |
0.00123 |
0.00659 |
0.0114 |
| 2.5 |
0.973 |
316.00 |
0.00900 |
0.00124 |
0.00657 |
0.0114 |
| 2.6 |
0.971 |
398.00 |
0.00900 |
0.00125 |
0.00654 |
0.0115 |
| 2.7 |
0.969 |
501.00 |
0.00900 |
0.00125 |
0.00655 |
0.0114 |
| 2.8 |
0.961 |
631.00 |
0.00900 |
0.00130 |
0.00646 |
0.0115 |
| 2.9 |
0.941 |
794.00 |
0.00900 |
0.00131 |
0.00642 |
0.0116 |
| 3.0 |
0.937 |
1000.00 |
0.00900 |
0.00134 |
0.00638 |
0.0116 |
| 3.1 |
0.929 |
1260.00 |
0.00900 |
0.00136 |
0.00633 |
0.0117 |
| 3.2 |
0.916 |
1580.00 |
0.00900 |
0.00136 |
0.00634 |
0.0117 |
| 3.3 |
0.894 |
2000.00 |
0.00900 |
0.00139 |
0.00627 |
0.0117 |
| 3.4 |
0.870 |
2510.00 |
0.00900 |
0.00141 |
0.00624 |
0.0118 |
| 3.5 |
0.846 |
3160.00 |
0.00900 |
0.00149 |
0.00607 |
0.0119 |
| 3.6 |
0.806 |
3980.00 |
0.00900 |
0.00163 |
0.00581 |
0.0122 |
| 3.7 |
0.723 |
5010.00 |
0.00900 |
0.00170 |
0.00567 |
0.0123 |
| 3.8 |
0.645 |
6310.00 |
0.00900 |
0.00171 |
0.00565 |
0.0123 |
| 3.9 |
0.557 |
7940.00 |
0.00900 |
0.00186 |
0.00536 |
0.0126 |
| 4.0 |
0.470 |
10000.00 |
0.00900 |
0.00222 |
0.00466 |
0.0133 |
| 4.1 |
0.386 |
12600.00 |
0.00857 |
0.00212 |
0.00441 |
0.0127 |
| 4.2 |
0.308 |
15800.00 |
0.00857 |
0.00235 |
0.00396 |
0.0132 |
| 4.3 |
0.228 |
20000.00 |
0.00857 |
0.00277 |
0.00314 |
0.0140 |
Not Monotone

| 0.0 |
1.00 |
1.000 |
0.00870 |
0.00104 |
0.00672 |
0.0115 |
| 0.1 |
1.26 |
0.993 |
0.00915 |
0.00123 |
0.00674 |
0.0116 |
| 0.2 |
1.58 |
0.993 |
0.00915 |
0.00123 |
0.00674 |
0.0116 |
| 0.3 |
2.00 |
0.993 |
0.00915 |
0.00123 |
0.00674 |
0.0116 |
| 0.4 |
2.51 |
0.991 |
0.00915 |
0.00123 |
0.00675 |
0.0116 |
| 0.5 |
3.16 |
0.990 |
0.00916 |
0.00123 |
0.00675 |
0.0116 |
| 0.6 |
3.98 |
0.990 |
0.00916 |
0.00123 |
0.00675 |
0.0116 |
| 0.7 |
5.01 |
0.990 |
0.00903 |
0.00122 |
0.00664 |
0.0114 |
| 0.8 |
6.31 |
0.990 |
0.00903 |
0.00122 |
0.00664 |
0.0114 |
| 0.9 |
7.94 |
0.990 |
0.00903 |
0.00122 |
0.00664 |
0.0114 |
| 1.0 |
10.00 |
0.990 |
0.00903 |
0.00122 |
0.00664 |
0.0114 |
| 1.1 |
12.60 |
0.988 |
0.00890 |
0.00121 |
0.00653 |
0.0113 |
| 1.2 |
15.80 |
0.988 |
0.00890 |
0.00121 |
0.00653 |
0.0113 |
| 1.3 |
20.00 |
0.988 |
0.00890 |
0.00121 |
0.00653 |
0.0113 |
| 1.4 |
25.10 |
0.988 |
0.00892 |
0.00121 |
0.00655 |
0.0113 |
| 1.5 |
31.60 |
0.988 |
0.00892 |
0.00121 |
0.00655 |
0.0113 |
| 1.6 |
39.80 |
0.988 |
0.00892 |
0.00121 |
0.00655 |
0.0113 |
| 1.7 |
50.10 |
0.987 |
0.00881 |
0.00120 |
0.00645 |
0.0112 |
| 1.8 |
63.10 |
0.987 |
0.00883 |
0.00121 |
0.00647 |
0.0112 |
| 1.9 |
79.40 |
0.985 |
0.00884 |
0.00121 |
0.00647 |
0.0112 |
| 2.0 |
100.00 |
0.984 |
0.00886 |
0.00121 |
0.00649 |
0.0112 |
| 2.1 |
126.00 |
0.982 |
0.00891 |
0.00122 |
0.00652 |
0.0113 |
| 2.2 |
158.00 |
0.981 |
0.00893 |
0.00122 |
0.00654 |
0.0113 |
| 2.3 |
200.00 |
0.980 |
0.00897 |
0.00123 |
0.00657 |
0.0114 |
| 2.4 |
251.00 |
0.980 |
0.00899 |
0.00123 |
0.00658 |
0.0114 |
| 2.5 |
316.00 |
0.973 |
0.00900 |
0.00124 |
0.00657 |
0.0114 |
| 2.6 |
398.00 |
0.971 |
0.00909 |
0.00125 |
0.00663 |
0.0115 |
| 2.7 |
501.00 |
0.969 |
0.00894 |
0.00125 |
0.00649 |
0.0114 |
| 2.8 |
631.00 |
0.961 |
0.00924 |
0.00130 |
0.00670 |
0.0118 |
| 2.9 |
794.00 |
0.941 |
0.00923 |
0.00131 |
0.00665 |
0.0118 |
| 3.0 |
1000.00 |
0.937 |
0.00929 |
0.00134 |
0.00668 |
0.0119 |
| 3.1 |
1260.00 |
0.929 |
0.00938 |
0.00136 |
0.00671 |
0.0120 |
| 3.2 |
1580.00 |
0.916 |
0.00899 |
0.00136 |
0.00633 |
0.0116 |
| 3.3 |
2000.00 |
0.894 |
0.00884 |
0.00139 |
0.00612 |
0.0116 |
| 3.4 |
2510.00 |
0.870 |
0.00865 |
0.00141 |
0.00589 |
0.0114 |
| 3.5 |
3160.00 |
0.846 |
0.00903 |
0.00149 |
0.00610 |
0.0120 |
| 3.6 |
3980.00 |
0.806 |
0.00946 |
0.00163 |
0.00627 |
0.0126 |
| 3.7 |
5010.00 |
0.723 |
0.00911 |
0.00170 |
0.00577 |
0.0124 |
| 3.8 |
6310.00 |
0.645 |
0.00852 |
0.00171 |
0.00518 |
0.0119 |
| 3.9 |
7940.00 |
0.557 |
0.00876 |
0.00186 |
0.00512 |
0.0124 |
| 4.0 |
10000.00 |
0.470 |
0.01020 |
0.00222 |
0.00583 |
0.0145 |
| 4.1 |
12600.00 |
0.386 |
0.00813 |
0.00212 |
0.00397 |
0.0123 |
| 4.2 |
15800.00 |
0.308 |
0.00826 |
0.00235 |
0.00365 |
0.0129 |
| 4.3 |
20000.00 |
0.228 |
0.00946 |
0.00277 |
0.00404 |
0.0149 |
Vaccine efficacy (monotone)

| 0.0 |
1.000 |
1.00 |
0.258 |
0.115 |
0.032000 |
0.484 |
| 0.1 |
0.993 |
1.26 |
0.258 |
0.127 |
0.008860 |
0.507 |
| 0.2 |
0.993 |
1.58 |
0.258 |
0.127 |
0.008860 |
0.507 |
| 0.3 |
0.993 |
2.00 |
0.258 |
0.127 |
0.008860 |
0.507 |
| 0.4 |
0.991 |
2.51 |
0.258 |
0.127 |
0.008780 |
0.507 |
| 0.5 |
0.990 |
3.16 |
0.258 |
0.127 |
0.008710 |
0.507 |
| 0.6 |
0.990 |
3.98 |
0.258 |
0.127 |
0.008710 |
0.507 |
| 0.7 |
0.990 |
5.01 |
0.262 |
0.126 |
0.015200 |
0.510 |
| 0.8 |
0.990 |
6.31 |
0.262 |
0.126 |
0.015200 |
0.510 |
| 0.9 |
0.990 |
7.94 |
0.262 |
0.126 |
0.015200 |
0.510 |
| 1.0 |
0.990 |
10.00 |
0.262 |
0.126 |
0.015200 |
0.510 |
| 1.1 |
0.988 |
12.60 |
0.265 |
0.125 |
0.019400 |
0.511 |
| 1.2 |
0.988 |
15.80 |
0.265 |
0.125 |
0.019400 |
0.511 |
| 1.3 |
0.988 |
20.00 |
0.265 |
0.125 |
0.019400 |
0.511 |
| 1.4 |
0.988 |
25.10 |
0.265 |
0.125 |
0.019100 |
0.511 |
| 1.5 |
0.988 |
31.60 |
0.265 |
0.125 |
0.019100 |
0.511 |
| 1.6 |
0.988 |
39.80 |
0.265 |
0.125 |
0.019100 |
0.511 |
| 1.7 |
0.987 |
50.10 |
0.265 |
0.125 |
0.019900 |
0.510 |
| 1.8 |
0.987 |
63.10 |
0.265 |
0.125 |
0.019600 |
0.510 |
| 1.9 |
0.985 |
79.40 |
0.265 |
0.125 |
0.019500 |
0.510 |
| 2.0 |
0.984 |
100.00 |
0.265 |
0.125 |
0.019100 |
0.511 |
| 2.1 |
0.982 |
126.00 |
0.265 |
0.126 |
0.018200 |
0.512 |
| 2.2 |
0.981 |
158.00 |
0.265 |
0.126 |
0.017800 |
0.512 |
| 2.3 |
0.980 |
200.00 |
0.265 |
0.126 |
0.017100 |
0.513 |
| 2.4 |
0.980 |
251.00 |
0.265 |
0.127 |
0.016700 |
0.513 |
| 2.5 |
0.973 |
316.00 |
0.265 |
0.127 |
0.015400 |
0.515 |
| 2.6 |
0.971 |
398.00 |
0.265 |
0.128 |
0.013700 |
0.516 |
| 2.7 |
0.969 |
501.00 |
0.265 |
0.128 |
0.014200 |
0.516 |
| 2.8 |
0.961 |
631.00 |
0.265 |
0.131 |
0.008010 |
0.522 |
| 2.9 |
0.941 |
794.00 |
0.265 |
0.132 |
0.005880 |
0.524 |
| 3.0 |
0.937 |
1000.00 |
0.265 |
0.134 |
0.002980 |
0.527 |
| 3.1 |
0.929 |
1260.00 |
0.265 |
0.135 |
-0.000187 |
0.530 |
| 3.2 |
0.916 |
1580.00 |
0.265 |
0.135 |
0.000372 |
0.530 |
| 3.3 |
0.894 |
2000.00 |
0.265 |
0.137 |
-0.004330 |
0.534 |
| 3.4 |
0.870 |
2510.00 |
0.265 |
0.138 |
-0.006200 |
0.536 |
| 3.5 |
0.846 |
3160.00 |
0.265 |
0.144 |
-0.018000 |
0.548 |
| 3.6 |
0.806 |
3980.00 |
0.265 |
0.154 |
-0.036000 |
0.566 |
| 3.7 |
0.723 |
5010.00 |
0.265 |
0.159 |
-0.046400 |
0.576 |
| 3.8 |
0.645 |
6310.00 |
0.265 |
0.159 |
-0.047600 |
0.578 |
| 3.9 |
0.557 |
7940.00 |
0.265 |
0.170 |
-0.068500 |
0.598 |
| 4.0 |
0.470 |
10000.00 |
0.265 |
0.197 |
-0.121000 |
0.651 |
| 4.1 |
0.386 |
12600.00 |
0.300 |
0.188 |
-0.068800 |
0.669 |
| 4.2 |
0.308 |
15800.00 |
0.300 |
0.206 |
-0.103000 |
0.703 |
| 4.3 |
0.228 |
20000.00 |
0.300 |
0.238 |
-0.165000 |
0.766 |
IgG3 V1V2 B.CaseA-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00870 |
0.00104 |
0.006660 |
0.01070 |
| 0.1 |
0.9160 |
1.26 |
0.00851 |
0.00144 |
0.005680 |
0.01130 |
| 0.2 |
0.9110 |
1.58 |
0.00838 |
0.00144 |
0.005560 |
0.01120 |
| 0.3 |
0.9090 |
2.00 |
0.00838 |
0.00148 |
0.005490 |
0.01130 |
| 0.4 |
0.8870 |
2.51 |
0.00834 |
0.00147 |
0.005450 |
0.01120 |
| 0.5 |
0.8860 |
3.16 |
0.00826 |
0.00145 |
0.005420 |
0.01110 |
| 0.6 |
0.8690 |
3.98 |
0.00826 |
0.00151 |
0.005290 |
0.01120 |
| 0.7 |
0.8580 |
5.01 |
0.00799 |
0.00150 |
0.005040 |
0.01090 |
| 0.8 |
0.8570 |
6.31 |
0.00783 |
0.00150 |
0.004890 |
0.01080 |
| 0.9 |
0.8480 |
7.94 |
0.00782 |
0.00153 |
0.004820 |
0.01080 |
| 1.0 |
0.8200 |
10.00 |
0.00766 |
0.00148 |
0.004760 |
0.01050 |
| 1.1 |
0.7670 |
12.60 |
0.00766 |
0.00152 |
0.004670 |
0.01060 |
| 1.2 |
0.7380 |
15.80 |
0.00750 |
0.00150 |
0.004550 |
0.01040 |
| 1.3 |
0.7020 |
20.00 |
0.00735 |
0.00150 |
0.004400 |
0.01030 |
| 1.4 |
0.6650 |
25.10 |
0.00735 |
0.00160 |
0.004220 |
0.01050 |
| 1.5 |
0.6210 |
31.60 |
0.00713 |
0.00158 |
0.004040 |
0.01020 |
| 1.6 |
0.5750 |
39.80 |
0.00650 |
0.00152 |
0.003520 |
0.00949 |
| 1.7 |
0.4890 |
50.10 |
0.00650 |
0.00162 |
0.003320 |
0.00968 |
| 1.8 |
0.4480 |
63.10 |
0.00643 |
0.00167 |
0.003140 |
0.00971 |
| 1.9 |
0.3790 |
79.40 |
0.00607 |
0.00175 |
0.002640 |
0.00951 |
| 2.0 |
0.3170 |
100.00 |
0.00559 |
0.00177 |
0.002130 |
0.00905 |
| 2.1 |
0.2760 |
126.00 |
0.00559 |
0.00187 |
0.001940 |
0.00925 |
| 2.2 |
0.2270 |
158.00 |
0.00558 |
0.00205 |
0.001560 |
0.00959 |
| 2.3 |
0.2010 |
200.00 |
0.00558 |
0.00232 |
0.001030 |
0.01010 |
| 2.4 |
0.1610 |
251.00 |
0.00558 |
0.00236 |
0.000952 |
0.01020 |
| 2.5 |
0.1300 |
316.00 |
0.00558 |
0.00234 |
0.000992 |
0.01020 |
| 2.6 |
0.1020 |
398.00 |
0.00558 |
0.00247 |
0.000735 |
0.01040 |
| 2.7 |
0.0838 |
501.00 |
0.00558 |
0.00294 |
-0.000189 |
0.01130 |
| 2.8 |
0.0584 |
631.00 |
0.00558 |
0.00543 |
-0.005070 |
0.01620 |
| 2.9 |
0.0536 |
794.00 |
0.00558 |
0.00542 |
-0.005040 |
0.01620 |
| 3.0 |
0.0428 |
1000.00 |
0.00558 |
0.01250 |
-0.019000 |
0.03020 |
| 3.1 |
0.0327 |
1260.00 |
0.00558 |
0.01820 |
-0.030000 |
0.04120 |
| 3.2 |
0.0307 |
1580.00 |
0.00558 |
0.02400 |
-0.041500 |
0.05260 |
| 3.3 |
0.0304 |
2000.00 |
0.00558 |
0.02900 |
-0.051300 |
0.06250 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00870 |
0.00104 |
0.006720 |
0.01150 |
| 0.1 |
1.26 |
0.9160 |
0.00851 |
0.00144 |
0.005680 |
0.01130 |
| 0.2 |
1.58 |
0.9110 |
0.00830 |
0.00144 |
0.005480 |
0.01110 |
| 0.3 |
2.00 |
0.9090 |
0.00847 |
0.00148 |
0.005570 |
0.01140 |
| 0.4 |
2.51 |
0.8870 |
0.00834 |
0.00147 |
0.005450 |
0.01120 |
| 0.5 |
3.16 |
0.8860 |
0.00811 |
0.00145 |
0.005260 |
0.01090 |
| 0.6 |
3.98 |
0.8690 |
0.00842 |
0.00151 |
0.005450 |
0.01140 |
| 0.7 |
5.01 |
0.8580 |
0.00799 |
0.00150 |
0.005040 |
0.01090 |
| 0.8 |
6.31 |
0.8570 |
0.00783 |
0.00150 |
0.004890 |
0.01080 |
| 0.9 |
7.94 |
0.8480 |
0.00782 |
0.00153 |
0.004830 |
0.01080 |
| 1.0 |
10.00 |
0.8200 |
0.00764 |
0.00148 |
0.004750 |
0.01050 |
| 1.1 |
12.60 |
0.7670 |
0.00767 |
0.00152 |
0.004690 |
0.01070 |
| 1.2 |
15.80 |
0.7380 |
0.00750 |
0.00150 |
0.004550 |
0.01040 |
| 1.3 |
20.00 |
0.7020 |
0.00715 |
0.00150 |
0.004210 |
0.01010 |
| 1.4 |
25.10 |
0.6650 |
0.00755 |
0.00160 |
0.004420 |
0.01070 |
| 1.5 |
31.60 |
0.6210 |
0.00713 |
0.00158 |
0.004040 |
0.01020 |
| 1.6 |
39.80 |
0.5750 |
0.00637 |
0.00152 |
0.003390 |
0.00936 |
| 1.7 |
50.10 |
0.4890 |
0.00664 |
0.00162 |
0.003460 |
0.00982 |
| 1.8 |
63.10 |
0.4480 |
0.00643 |
0.00167 |
0.003140 |
0.00971 |
| 1.9 |
79.40 |
0.3790 |
0.00607 |
0.00175 |
0.002640 |
0.00951 |
| 2.0 |
100.00 |
0.3170 |
0.00557 |
0.00177 |
0.002110 |
0.00903 |
| 2.1 |
126.00 |
0.2760 |
0.00561 |
0.00187 |
0.001960 |
0.00927 |
| 2.2 |
158.00 |
0.2270 |
0.00551 |
0.00205 |
0.001490 |
0.00953 |
| 2.3 |
200.00 |
0.2010 |
0.00579 |
0.00232 |
0.001240 |
0.01030 |
| 2.4 |
251.00 |
0.1610 |
0.00552 |
0.00236 |
0.000900 |
0.01010 |
| 2.5 |
316.00 |
0.1300 |
0.00481 |
0.00234 |
0.000227 |
0.00940 |
| 2.6 |
398.00 |
0.1020 |
0.00454 |
0.00247 |
-0.000305 |
0.00938 |
| 2.7 |
501.00 |
0.0838 |
0.00529 |
0.00294 |
-0.000472 |
0.01110 |
| 2.8 |
631.00 |
0.0584 |
0.00809 |
0.00543 |
-0.002550 |
0.01870 |
| 2.9 |
794.00 |
0.0536 |
0.00744 |
0.00542 |
-0.003190 |
0.01810 |
| 3.0 |
1000.00 |
0.0428 |
0.01450 |
0.01250 |
-0.010100 |
0.03910 |
| 3.1 |
1260.00 |
0.0327 |
0.02130 |
0.01820 |
-0.014300 |
0.05690 |
| 3.2 |
1580.00 |
0.0307 |
0.02540 |
0.02400 |
-0.021600 |
0.07250 |
| 3.3 |
2000.00 |
0.0304 |
0.02970 |
0.02900 |
-0.027200 |
0.08660 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.290 |
0.113 |
0.0684 |
0.511 |
| 0.1 |
0.9160 |
1.26 |
0.305 |
0.139 |
0.0330 |
0.577 |
| 0.2 |
0.9110 |
1.58 |
0.315 |
0.138 |
0.0455 |
0.585 |
| 0.3 |
0.9090 |
2.00 |
0.315 |
0.140 |
0.0402 |
0.591 |
| 0.4 |
0.8870 |
2.51 |
0.319 |
0.140 |
0.0442 |
0.593 |
| 0.5 |
0.8860 |
3.16 |
0.325 |
0.138 |
0.0548 |
0.596 |
| 0.6 |
0.8690 |
3.98 |
0.325 |
0.143 |
0.0458 |
0.605 |
| 0.7 |
0.8580 |
5.01 |
0.347 |
0.141 |
0.0716 |
0.623 |
| 0.8 |
0.8570 |
6.31 |
0.360 |
0.140 |
0.0862 |
0.634 |
| 0.9 |
0.8480 |
7.94 |
0.361 |
0.142 |
0.0831 |
0.639 |
| 1.0 |
0.8200 |
10.00 |
0.375 |
0.137 |
0.1060 |
0.644 |
| 1.1 |
0.7670 |
12.60 |
0.375 |
0.141 |
0.0990 |
0.650 |
| 1.2 |
0.7380 |
15.80 |
0.388 |
0.139 |
0.1160 |
0.659 |
| 1.3 |
0.7020 |
20.00 |
0.400 |
0.138 |
0.1300 |
0.670 |
| 1.4 |
0.6650 |
25.10 |
0.400 |
0.145 |
0.1160 |
0.684 |
| 1.5 |
0.6210 |
31.60 |
0.418 |
0.143 |
0.1380 |
0.697 |
| 1.6 |
0.5750 |
39.80 |
0.469 |
0.136 |
0.2010 |
0.736 |
| 1.7 |
0.4890 |
50.10 |
0.469 |
0.144 |
0.1870 |
0.751 |
| 1.8 |
0.4480 |
63.10 |
0.475 |
0.147 |
0.1860 |
0.764 |
| 1.9 |
0.3790 |
79.40 |
0.504 |
0.152 |
0.2050 |
0.803 |
| 2.0 |
0.3170 |
100.00 |
0.543 |
0.152 |
0.2450 |
0.841 |
| 2.1 |
0.2760 |
126.00 |
0.543 |
0.160 |
0.2300 |
0.856 |
| 2.2 |
0.2270 |
158.00 |
0.545 |
0.174 |
0.2030 |
0.886 |
| 2.3 |
0.2010 |
200.00 |
0.545 |
0.196 |
0.1610 |
0.928 |
| 2.4 |
0.1610 |
251.00 |
0.545 |
0.199 |
0.1550 |
0.934 |
| 2.5 |
0.1300 |
316.00 |
0.545 |
0.197 |
0.1590 |
0.931 |
| 2.6 |
0.1020 |
398.00 |
0.545 |
0.207 |
0.1380 |
0.951 |
| 2.7 |
0.0838 |
501.00 |
0.545 |
0.245 |
0.0644 |
1.020 |
| 2.8 |
0.0584 |
631.00 |
0.545 |
0.446 |
-0.3300 |
1.420 |
| 2.9 |
0.0536 |
794.00 |
0.545 |
0.445 |
-0.3280 |
1.420 |
| 3.0 |
0.0428 |
1000.00 |
0.545 |
1.030 |
-1.4700 |
2.550 |
| 3.1 |
0.0327 |
1260.00 |
0.545 |
1.480 |
-2.3700 |
3.450 |
| 3.2 |
0.0307 |
1580.00 |
0.545 |
1.960 |
-3.3000 |
4.390 |
| 3.3 |
0.0304 |
2000.00 |
0.545 |
2.370 |
-4.1000 |
5.190 |
IgG3 V1V2 C.1086-gp70
Monotone

| 0.0 |
1.0000 |
1.00 |
0.00870 |
0.00104 |
0.006660 |
0.0107 |
| 0.1 |
0.9660 |
1.26 |
0.00861 |
0.00123 |
0.006190 |
0.0110 |
| 0.2 |
0.9650 |
1.58 |
0.00861 |
0.00124 |
0.006180 |
0.0110 |
| 0.3 |
0.9650 |
2.00 |
0.00861 |
0.00124 |
0.006180 |
0.0110 |
| 0.4 |
0.9600 |
2.51 |
0.00861 |
0.00125 |
0.006170 |
0.0110 |
| 0.5 |
0.9580 |
3.16 |
0.00861 |
0.00125 |
0.006160 |
0.0111 |
| 0.6 |
0.9570 |
3.98 |
0.00852 |
0.00123 |
0.006120 |
0.0109 |
| 0.7 |
0.9510 |
5.01 |
0.00852 |
0.00124 |
0.006100 |
0.0109 |
| 0.8 |
0.9430 |
6.31 |
0.00852 |
0.00124 |
0.006090 |
0.0110 |
| 0.9 |
0.9400 |
7.94 |
0.00852 |
0.00126 |
0.006050 |
0.0110 |
| 1.0 |
0.9340 |
10.00 |
0.00852 |
0.00128 |
0.006020 |
0.0110 |
| 1.1 |
0.9250 |
12.60 |
0.00852 |
0.00130 |
0.005980 |
0.0111 |
| 1.2 |
0.9200 |
15.80 |
0.00846 |
0.00128 |
0.005960 |
0.0110 |
| 1.3 |
0.9170 |
20.00 |
0.00846 |
0.00127 |
0.005960 |
0.0110 |
| 1.4 |
0.9090 |
25.10 |
0.00846 |
0.00131 |
0.005900 |
0.0110 |
| 1.5 |
0.8860 |
31.60 |
0.00846 |
0.00129 |
0.005940 |
0.0110 |
| 1.6 |
0.8750 |
39.80 |
0.00846 |
0.00129 |
0.005940 |
0.0110 |
| 1.7 |
0.8520 |
50.10 |
0.00846 |
0.00132 |
0.005870 |
0.0111 |
| 1.8 |
0.8350 |
63.10 |
0.00846 |
0.00133 |
0.005860 |
0.0111 |
| 1.9 |
0.8310 |
79.40 |
0.00846 |
0.00138 |
0.005760 |
0.0112 |
| 2.0 |
0.8020 |
100.00 |
0.00846 |
0.00135 |
0.005820 |
0.0111 |
| 2.1 |
0.7610 |
126.00 |
0.00846 |
0.00140 |
0.005710 |
0.0112 |
| 2.2 |
0.7050 |
158.00 |
0.00846 |
0.00147 |
0.005580 |
0.0113 |
| 2.3 |
0.6510 |
200.00 |
0.00846 |
0.00155 |
0.005420 |
0.0115 |
| 2.4 |
0.6130 |
251.00 |
0.00846 |
0.00166 |
0.005200 |
0.0117 |
| 2.5 |
0.5550 |
316.00 |
0.00846 |
0.00182 |
0.004900 |
0.0120 |
| 2.6 |
0.4990 |
398.00 |
0.00846 |
0.00184 |
0.004850 |
0.0121 |
| 2.7 |
0.4260 |
501.00 |
0.00846 |
0.00211 |
0.004320 |
0.0126 |
| 2.8 |
0.3480 |
631.00 |
0.00846 |
0.00261 |
0.003350 |
0.0136 |
| 2.9 |
0.2870 |
794.00 |
0.00846 |
0.00288 |
0.002810 |
0.0141 |
| 3.0 |
0.2430 |
1000.00 |
0.00846 |
0.00326 |
0.002070 |
0.0149 |
| 3.1 |
0.2000 |
1260.00 |
0.00846 |
0.00319 |
0.002210 |
0.0147 |
| 3.2 |
0.1500 |
1580.00 |
0.00703 |
0.00287 |
0.001400 |
0.0127 |
| 3.3 |
0.1230 |
2000.00 |
0.00703 |
0.00352 |
0.000127 |
0.0139 |
| 3.4 |
0.0939 |
2510.00 |
0.00703 |
0.00453 |
-0.001840 |
0.0159 |
| 3.5 |
0.0695 |
3160.00 |
0.00703 |
0.00525 |
-0.003260 |
0.0173 |
| 3.6 |
0.0583 |
3980.00 |
0.00703 |
0.00477 |
-0.002320 |
0.0164 |
| 3.7 |
0.0421 |
5010.00 |
0.00703 |
0.00565 |
-0.004060 |
0.0181 |
| 3.8 |
0.0253 |
6310.00 |
0.00703 |
0.00904 |
-0.010700 |
0.0247 |
Not Monotone

| 0.0 |
1.00 |
1.0000 |
0.00870 |
0.00104 |
6.72e-03 |
0.0115 |
| 0.1 |
1.26 |
0.9660 |
0.00858 |
0.00123 |
6.16e-03 |
0.0110 |
| 0.2 |
1.58 |
0.9650 |
0.00860 |
0.00124 |
6.17e-03 |
0.0110 |
| 0.3 |
2.00 |
0.9650 |
0.00860 |
0.00124 |
6.17e-03 |
0.0110 |
| 0.4 |
2.51 |
0.9600 |
0.00862 |
0.00125 |
6.18e-03 |
0.0111 |
| 0.5 |
3.16 |
0.9580 |
0.00865 |
0.00125 |
6.20e-03 |
0.0111 |
| 0.6 |
3.98 |
0.9570 |
0.00837 |
0.00123 |
5.97e-03 |
0.0108 |
| 0.7 |
5.01 |
0.9510 |
0.00844 |
0.00124 |
6.02e-03 |
0.0109 |
| 0.8 |
6.31 |
0.9430 |
0.00842 |
0.00124 |
5.98e-03 |
0.0108 |
| 0.9 |
7.94 |
0.9400 |
0.00855 |
0.00126 |
6.08e-03 |
0.0110 |
| 1.0 |
10.00 |
0.9340 |
0.00862 |
0.00128 |
6.12e-03 |
0.0111 |
| 1.1 |
12.60 |
0.9250 |
0.00875 |
0.00130 |
6.20e-03 |
0.0113 |
| 1.2 |
15.80 |
0.9200 |
0.00838 |
0.00128 |
5.88e-03 |
0.0109 |
| 1.3 |
20.00 |
0.9170 |
0.00821 |
0.00127 |
5.72e-03 |
0.0107 |
| 1.4 |
25.10 |
0.9090 |
0.00841 |
0.00131 |
5.85e-03 |
0.0110 |
| 1.5 |
31.60 |
0.8860 |
0.00811 |
0.00129 |
5.58e-03 |
0.0106 |
| 1.6 |
39.80 |
0.8750 |
0.00803 |
0.00129 |
5.51e-03 |
0.0106 |
| 1.7 |
50.10 |
0.8520 |
0.00816 |
0.00132 |
5.56e-03 |
0.0107 |
| 1.8 |
63.10 |
0.8350 |
0.00802 |
0.00133 |
5.42e-03 |
0.0106 |
| 1.9 |
79.40 |
0.8310 |
0.00829 |
0.00138 |
5.59e-03 |
0.0110 |
| 2.0 |
100.00 |
0.8020 |
0.00779 |
0.00135 |
5.15e-03 |
0.0104 |
| 2.1 |
126.00 |
0.7610 |
0.00799 |
0.00140 |
5.24e-03 |
0.0107 |
| 2.2 |
158.00 |
0.7050 |
0.00794 |
0.00147 |
5.05e-03 |
0.0108 |
| 2.3 |
200.00 |
0.6510 |
0.00809 |
0.00155 |
5.05e-03 |
0.0111 |
| 2.4 |
251.00 |
0.6130 |
0.00855 |
0.00166 |
5.29e-03 |
0.0118 |
| 2.5 |
316.00 |
0.5550 |
0.00909 |
0.00182 |
5.53e-03 |
0.0126 |
| 2.6 |
398.00 |
0.4990 |
0.00856 |
0.00184 |
4.95e-03 |
0.0122 |
| 2.7 |
501.00 |
0.4260 |
0.00870 |
0.00211 |
4.56e-03 |
0.0128 |
| 2.8 |
631.00 |
0.3480 |
0.01030 |
0.00261 |
5.15e-03 |
0.0154 |
| 2.9 |
794.00 |
0.2870 |
0.01020 |
0.00288 |
4.55e-03 |
0.0158 |
| 3.0 |
1000.00 |
0.2430 |
0.00943 |
0.00326 |
3.04e-03 |
0.0158 |
| 3.1 |
1260.00 |
0.2000 |
0.00933 |
0.00319 |
3.08e-03 |
0.0156 |
| 3.2 |
1580.00 |
0.1500 |
0.00647 |
0.00287 |
8.45e-04 |
0.0121 |
| 3.3 |
2000.00 |
0.1230 |
0.00758 |
0.00352 |
6.85e-04 |
0.0145 |
| 3.4 |
2510.00 |
0.0939 |
0.00890 |
0.00453 |
3.07e-05 |
0.0178 |
| 3.5 |
3160.00 |
0.0695 |
0.01130 |
0.00525 |
1.03e-03 |
0.0216 |
| 3.6 |
3980.00 |
0.0583 |
0.00945 |
0.00477 |
1.01e-04 |
0.0188 |
| 3.7 |
5010.00 |
0.0421 |
0.01020 |
0.00565 |
-8.55e-04 |
0.0213 |
| 3.8 |
6310.00 |
0.0253 |
0.01820 |
0.00904 |
4.83e-04 |
0.0359 |
Vaccine efficacy (monotone)

| 0.0 |
1.0000 |
1.00 |
0.290 |
0.113 |
0.06840 |
0.511 |
| 0.1 |
0.9660 |
1.26 |
0.297 |
0.125 |
0.05200 |
0.542 |
| 0.2 |
0.9650 |
1.58 |
0.297 |
0.125 |
0.05160 |
0.542 |
| 0.3 |
0.9650 |
2.00 |
0.297 |
0.125 |
0.05160 |
0.542 |
| 0.4 |
0.9600 |
2.51 |
0.297 |
0.126 |
0.05060 |
0.543 |
| 0.5 |
0.9580 |
3.16 |
0.297 |
0.126 |
0.05010 |
0.544 |
| 0.6 |
0.9570 |
3.98 |
0.304 |
0.124 |
0.06050 |
0.547 |
| 0.7 |
0.9510 |
5.01 |
0.304 |
0.125 |
0.05940 |
0.548 |
| 0.8 |
0.9430 |
6.31 |
0.304 |
0.125 |
0.05870 |
0.549 |
| 0.9 |
0.9400 |
7.94 |
0.304 |
0.127 |
0.05570 |
0.552 |
| 1.0 |
0.9340 |
10.00 |
0.304 |
0.127 |
0.05400 |
0.553 |
| 1.1 |
0.9250 |
12.60 |
0.304 |
0.129 |
0.05110 |
0.556 |
| 1.2 |
0.9200 |
15.80 |
0.309 |
0.127 |
0.05970 |
0.558 |
| 1.3 |
0.9170 |
20.00 |
0.309 |
0.127 |
0.06000 |
0.557 |
| 1.4 |
0.9090 |
25.10 |
0.309 |
0.129 |
0.05590 |
0.562 |
| 1.5 |
0.8860 |
31.60 |
0.309 |
0.128 |
0.05810 |
0.559 |
| 1.6 |
0.8750 |
39.80 |
0.309 |
0.128 |
0.05840 |
0.559 |
| 1.7 |
0.8520 |
50.10 |
0.309 |
0.130 |
0.05360 |
0.564 |
| 1.8 |
0.8350 |
63.10 |
0.309 |
0.130 |
0.05320 |
0.564 |
| 1.9 |
0.8310 |
79.40 |
0.309 |
0.134 |
0.04630 |
0.571 |
| 2.0 |
0.8020 |
100.00 |
0.309 |
0.132 |
0.05000 |
0.568 |
| 2.1 |
0.7610 |
126.00 |
0.309 |
0.136 |
0.04290 |
0.575 |
| 2.2 |
0.7050 |
158.00 |
0.309 |
0.140 |
0.03350 |
0.584 |
| 2.3 |
0.6510 |
200.00 |
0.309 |
0.146 |
0.02220 |
0.595 |
| 2.4 |
0.6130 |
251.00 |
0.309 |
0.154 |
0.00689 |
0.611 |
| 2.5 |
0.5550 |
316.00 |
0.309 |
0.165 |
-0.01480 |
0.632 |
| 2.6 |
0.4990 |
398.00 |
0.309 |
0.167 |
-0.01850 |
0.636 |
| 2.7 |
0.4260 |
501.00 |
0.309 |
0.187 |
-0.05810 |
0.676 |
| 2.8 |
0.3480 |
631.00 |
0.309 |
0.225 |
-0.13200 |
0.750 |
| 2.9 |
0.2870 |
794.00 |
0.309 |
0.246 |
-0.17400 |
0.792 |
| 3.0 |
0.2430 |
1000.00 |
0.309 |
0.276 |
-0.23300 |
0.850 |
| 3.1 |
0.2000 |
1260.00 |
0.309 |
0.270 |
-0.22100 |
0.839 |
| 3.2 |
0.1500 |
1580.00 |
0.426 |
0.242 |
-0.04820 |
0.901 |
| 3.3 |
0.1230 |
2000.00 |
0.426 |
0.294 |
-0.15000 |
1.000 |
| 3.4 |
0.0939 |
2510.00 |
0.426 |
0.375 |
-0.30800 |
1.160 |
| 3.5 |
0.0695 |
3160.00 |
0.426 |
0.433 |
-0.42300 |
1.270 |
| 3.6 |
0.0583 |
3980.00 |
0.426 |
0.394 |
-0.34700 |
1.200 |
| 3.7 |
0.0421 |
5010.00 |
0.426 |
0.466 |
-0.48700 |
1.340 |
| 3.8 |
0.0253 |
6310.00 |
0.426 |
0.741 |
-1.03000 |
1.880 |